Patents by Inventor Elsebet Ostergaard Nielsen

Elsebet Ostergaard Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-Aryloxy-8-aza-bicyclo[3.2.1]]oct-6-ene derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20090030035
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]oct-6-ene derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 7, 2006
    Publication date: January 29, 2009
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, David Tristram Brown, John Paul Redrobe, Elsebet Ostergaard Nielsen
  • Benzimidazole derivatives and their use for modulating the gabaalpha receptor complex
    Publication number: 20090030018
    Abstract: This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: April 18, 2006
    Publication date: January 29, 2009
    Inventors: Lene Teuber, Janus S. Larsen, Philip K. Ahring, Elsebet Ostergaard Nielsen, Naheed Mirza
  • Novel substituted heteroaryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20090023772
    Abstract: This invention relates to novel substituted heteroaryloxy alkylamines useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: August 24, 2005
    Publication date: January 22, 2009
    Inventors: Birgitte L. Eriksen, Dan Peters, Elsebet Ostergaard Nielsen, Jorgen Scheel-Kruger, Gunnar M. Olsen
  • NOVEL QUINUCLIDINE DERIVATIVES AND THEIR USE
    Publication number: 20090005390
    Abstract: This invention relates to novel quinuclidine derivatives and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: September 8, 2008
    Publication date: January 1, 2009
    Inventors: Dan PETERS, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Phillip K. Ahring, Tino Dyhring Jorgensen
  • 3-Heteroaryl-3,9-Diazabicyclo[3.3.1]Nonane Derivatives as Nicotinic Acetylcholine Receptor Agonists
    Publication number: 20090005388
    Abstract: This invention relates to novel 3,9-diazabicyclo[3.3.1]nonane derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: February 9, 2007
    Publication date: January 1, 2009
    Inventors: Dan Peters, Daniel B. Timmermann, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Jeppe Kejser Christensen
  • Imidazole Derivatives and Their Use for Modulating the Gabaa Receptor Complex
    Publication number: 20080312303
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: October 12, 2006
    Publication date: December 18, 2008
    Applicant: NeuroSearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Ostergaard Nielsen
  • 3,9-Diazabicyclo [3.3.1] Nonane Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080306078
    Abstract: This invention relates to novel 3,9-diazabicyclo[3.3.1]nonane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: February 9, 2007
    Publication date: December 11, 2008
    Inventors: Dan Peters, John Paul Redrobe, Elsebet Ostergaard Nielsen
  • Novel Diazabicycylic Aryl Derivatives and Their Medical Use
    Publication number: 20080280912
    Abstract: This invention relates to novel diazabicyclic aryl derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: December 5, 2006
    Publication date: November 13, 2008
    Inventors: Dan Peters, Daniel B. Timmermann, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring
  • Novel Substituted Diazabicyclo Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080280882
    Abstract: This invention relates to novel substituted diazabicyclo derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: April 3, 2006
    Publication date: November 13, 2008
    Applicant: NEUROSEARCH A/S
    Inventors: Dan Peters, Elsebet Ostergaard Nielsen, John Paul Redrobe
  • Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20080269229
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: July 1, 2008
    Publication date: October 30, 2008
    Inventors: Dan Peters, Birgitte L. Eriksen, Elsebet Ostergaard Nielsen, Jergen Scheel-Kruger, Gunnar M. Olsen
  • Dimeric Azacyclic Compounds and Their Use
    Publication number: 20080242668
    Abstract: This invention relates to azacyclic derivatives according of formula (I) and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or. disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the? termination of abuse of chemical substances.
    Type: Application
    Filed: February 1, 2005
    Publication date: October 2, 2008
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring Jorgensen, Daniel B. Timmermann
  • Diazabicyclic Aryl Derivatives as Cholinergic Receptor Modulators
    Publication number: 20080227773
    Abstract: This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemicals substances.
    Type: Application
    Filed: February 1, 2005
    Publication date: September 18, 2008
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring Jorgensen, Daniel B Timmermann
  • Diazabicyclic Aryl Derivatives as Nicotinic Acetylcholine Receptor Ligands
    Publication number: 20080227772
    Abstract: This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: February 1, 2005
    Publication date: September 18, 2008
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring Jorgensen, Philip K. Ahring, Daniel B. Timmermann
  • Enantiomers of 3-Heteroaryl-8H-8-Azabicyclo (3.2.1) Oct-2-Ene and their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080214820
    Abstract: This invention relates to novel enantiomers useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: December 15, 2005
    Publication date: September 4, 2008
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, David Tristram Brown, Borje Egestad, Eva Dam, David Spencer Jones, Brian Frostrup, Elsebet Ostergaard Nielsen, Gunnar M. Olsen, John Paul Redrobe
  • Novel azacyclic ethynyl derivatives
    Publication number: 20080188519
    Abstract: Azacyclic ethynyl derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: March 25, 2008
    Publication date: August 7, 2008
    Inventors: Dan Peters, Gurmar M. Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring Jorgensen, Philip K. Ahring
  • 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7407970
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 5, 2008
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Birgitte L. Eriksen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Gunnar M. Olsen
  • Novel Alkyl Substituted Piperidine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080176856
    Abstract: This invention relates to novel alkyl substituted piperazine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 14, 2005
    Publication date: July 24, 2008
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Jorgen Scheel-Kruger
  • Novel Diazabicyclic Aryl Derivatives and Their Medical Use
    Publication number: 20080161314
    Abstract: This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: February 13, 2006
    Publication date: July 3, 2008
    Applicant: NeuroSearch A/S
    Inventors: Dan Peters, Daniel B. Timmermann, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring
  • Novel Diazabicyclic Aryl Derivatives And Their Medical Use
    Publication number: 20080153806
    Abstract: This invention relates to novel diazabicyclic aryl derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: October 18, 2005
    Publication date: June 26, 2008
    Inventors: Dan Peters, Daniel B. Timmermann, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring Jorgensen
  • Diazabicyclic Aryl Derivatives and Their Use as Chinolinergic Ligands at the Nicotinic Acetylcholine Receptors
    Publication number: 20080146582
    Abstract: This invention relates to novel diazabicyclic aryl derivatives which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
    Type: Application
    Filed: February 13, 2006
    Publication date: June 19, 2008
    Inventors: Dan Peters, Daniel B Timmermann, Gunnar Olsen, Elsebet Ostergaard Nielsen, Tino Dyhring