Abstract: A novel gRNA-ligand binding complex is provided. This complex may be used to bring Type V Cas proteins and additional effectors to DNA for base editing. The design of the systems allows for the production of efficient modular components that provide flexibility when editing DNA.

Abstract: Methods and systems are disclosed herein for authenticating a user. A security device may use an object associated with a user and a device of the user to authenticate the user, for example, if the user has forgotten a password. A user may insert the object (e.g., a card, or other object) into the security device and may select an option to authenticate via a device that is trusted by both the security device and the user, rather than authenticating by entering a password at the security device.

Abstract: A blotter assembly for use in electrophoresis comprising a block and a closed cell silicone blotter pad adhesively attached thereto and restricted against accidental movement relative thereto.

Abstract: Methods and systems are disclosed herein for authenticating a user. A security device may use an object associated with a user and a device of the user to authenticate the user, for example, if the user has forgotten a password. A user may insert the object (e.g., a card, or other object) into the security device and may select an option to authenticate via a device that is trusted by both the security device and the user, rather than authenticating by entering a password at the security device.

Abstract: The present invention relates in general to a hand-held hair removal article. More specifically, the invention relates to a shaped flexible article adapted to scoop a hair removal compound, apply the hair removal compound to a hair removal area, and remove the hair removal compound and hair from the hair removal area.

Abstract: Methods and systems are disclosed herein for authenticating a user. A security device may use an object associated with a user and a device of the user to authenticate the user, for example, if the user has forgotten a password. A user may insert the object (e.g., a card, or other object) into the security device and may select an option to authenticate via a device that is trusted by both the security device and the user, rather than authenticating by entering a password at the security device.

Abstract: Provided herein are methods, compositions, and devices relating to administration of UV-B to a plant seed, plant seedling, or plant material to reduce disease and induce disease resistance.

Abstract: The present invention provides methods and compositions for immunizing a subject against malaria.

Abstract: A bale spreader including one or more rotors rotatably attached to a first and second support member is provided. The bale spreader includes an apron that extends below the rotor(s), and may be configured to operatively feed a particulate material into the rotor(s). The rotor(s) may include a plurality of flail knives or hammers configured to chop and/or shred a particulate material as the rotor(s) is/are rotated. The rotor(s) may be rotated by an optimized hydraulic system connected to the auxiliary hydraulic system of an agricultural implement or vehicle. Furthermore, the bale spreader may include a plurality of tines, screen members, and a flop bar configured to secure particulate material within the bale spreader.

Abstract: A storage solution for children's toys is described. A storage and transportation device for children's items (e.g., toys, puzzles, craft supplies, etc.) is specially designed to be used by children, including children under three years old. The storage solution may also include an improved zipper pull for opening and closing the storage and transportation device.

Abstract: A storage solution for children's toys is described. A storage and transportation device for children's items (e.g., toys, puzzles, craft supplies, etc.) is specially designed to be used by children, including children under three years old. The storage solution may also include an improved zipper pull for opening and closing the storage and transportation device.

Abstract: Disclosed is a device for the transport of temperature sensitive products including an insulated container, an insulated lid, a fastener to secure the lid to the container, an active heat exchanger, a thermal circuit to circulate heat exchange, a temperature sensor read by a temperature regulating circuit that maintains a temperature range, a power source, and a support frame that arranges the elements of the device with the overall center of mass at a location adapted for transport and storage of the device. Disclosed is also a method of transport for temperature sensitive products including securing the temperature sensitive product within an insulated container with a lid, removing heat from the container to maintain a temperature range, strapping the device onto the user's back and adjusting to the shape of the user, freeing both hands during transport of the device, and minimizing hindrances to user mobility caused by the device.

Abstract: Disclosed is a device for the transport of temperature sensitive products including an insulated container, an insulated lid, a fastener to secure the lid to the container, an active heat exchanger, a thermal circuit to circulate heat exchange, a temperature sensor read by a temperature regulating circuit that maintains a temperature range, a power source, and a support frame that arranges the elements of the device with the overall center of mass at a location adapted for transport and storage of the device. Disclosed is also a method of transport for temperature sensitive products including securing the temperature sensitive product within an insulated container with a lid, removing heat from the container to maintain a temperature range, strapping the device onto the user's back and adjusting to the shape of the user, freeing both hands during transport of the device, and minimizing hindrances to user mobility caused by the device.

Abstract: A timepiece apparatus is described that includes a display area that is able to present different colors, a timing mechanism that is able to track the passage of time, a display mechanism that is able to change the color of the display area, wherein the color corresponds to a time period, and an interface for associating the color displayed with the time period, wherein the association is customizable by a user.

Abstract: A temperature regulating device capable for environmentally adaptable transport of transporting temperature sensitive products is provided including an insulated casing having an interior portion and a temperature regulating device for maintaining the interior portion at a temperature range lower than ambient temperature exterior to the interior portion, wherein the temperature regulating device maintains the lower temperature without external power sources. The temperature device is personally portable and includes a backpack attachment for transporting by a single individual.