Patents by Inventor Eoin Brodie

Eoin Brodie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180223339
    Abstract: The present invention discloses methods and systems for designing and using organism-specific and/or operational taxon unit (OTU)-specific probes. The methods and systems allow for detecting, identifying and quantitating a plurality of biomolecules or microorganisms in a sample based on the hybridization or binding of target molecules in the sample with the probes. Some embodiments provide methods of selecting an oligonucleotide probe specific for a node on a clustering tree. Other embodiments provide methods of selecting organism-specific or OTU-specific oligonucleotide probes for use in accurately detecting a plurality of organisms in a sample with high confidence. Some embodiments provide methods and systems to detect the presence of a rare OTU in a sample.
    Type: Application
    Filed: March 2, 2018
    Publication date: August 9, 2018
    Inventors: Gary L. Andersen, Todd Z. DeSantis, Eoin Brodie
  • Publication number: 20150224152
    Abstract: The present invention relates to methods for treating or reducing the risk of or preventing diseases caused by or associated with pathogenic bacteria. More particularly, the present invention relates to methods for treating or reducing the risk of or preventing diseases caused by or associated with pathogenic bacteria of the gastrointestinal (GI) tract. The present invention further relates to methods for promoting pathways induced by commensal bacteria of the GI tract that lead to Th17 differentiation, which in turn leads to localized and systemic accumulation of Th17 cells. Compositions and medicaments are also described herein that are used alleviate and/or prevent symptoms associated with diseases caused by or associated with pathogenic bacteria. Accordingly, the compositions, medicaments and methods described herein may be used to address the needs of patients or subjects that would benefit from increased Th17 cell differentiation.
    Type: Application
    Filed: October 29, 2014
    Publication date: August 13, 2015
    Inventors: Dan Littman, Ivaylo Ivanov, Eoin Brodie, Yoshinori Umesaki, Kenya Honda
  • Publication number: 20120276149
    Abstract: The present invention relates to methods for treating or reducing the risk of or preventing diseases caused by or associated with pathogenic bacteria. More particularly, the present invention relates to methods for treating or reducing the risk of or preventing diseases caused by or associated with pathogenic bacteria of the gastrointestinal (GI) tract. The present invention further relates to methods for promoting pathways induced by commensal bacteria of the GI tract that lead to Th17 differentiation, which in turn leads to localized and systemic accumulation of Th17 cells. Compositions and medicaments are also described herein that are used alleviate and/or prevent symptoms associated with diseases caused by or associated with pathogenic bacteria. Accordingly, the compositions, medicaments and methods described herein may be used to address the needs of patients or subjects that would benefit from increased Th17 cell differentiation.
    Type: Application
    Filed: October 15, 2010
    Publication date: November 1, 2012
    Inventors: Dan Littman, Ivaylo Ivanov, Eoin Brodie, Yoshinori Umesaki, Kenya Honda
  • Publication number: 20120264637
    Abstract: Methods and systems for designing and using organism specific and/or operational taxon unit (OTU)-specific probes. The methods and systems allow for detecting, identifying and quantitating a plurality of biomolecules or microorganisms in a sample based on the hybridization or binding of target molecules in the sample with the probes, including the detection of rare OTU's in a sample. In some cases, methods are provided for selecting an oligonucleotide probe specific for a node on a clustering tree.
    Type: Application
    Filed: October 15, 2010
    Publication date: October 18, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jeanine Wiener-Kronish, Susan Lynch, Eoin Brodie
  • Publication number: 20120165215
    Abstract: The present invention discloses methods and systems for designing and using organism-specific and/or operational taxon unit (OTU)-specific probes. The methods and systems allow for detecting, identifying and quantitating a plurality of biomolecules or microrganisms in a sample based on the hybridization or binding of target molecules in the sample with the probes. Some embodiments provide methods of selecting an oligonucleotide probe specific for a node on a clustering tree. Other embodiments provide methods of selecting organism-specific or OTU-specific oligonucleotide probes for use in accurately detecting a plurality of organisms in a sample with high confidence. Some embodiments provide methods and systems to detect the presence of a rare OTU in a sample.
    Type: Application
    Filed: June 25, 2010
    Publication date: June 28, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Gary L. Andersen, Todd Z. Desantis, Eoin Brodie
  • Publication number: 20110195862
    Abstract: Polymer arrays suitable to perform quantitative and qualitative detection as well as sorting of a target molecules and related devices methods and systems.
    Type: Application
    Filed: February 8, 2011
    Publication date: August 11, 2011
    Inventors: Jennifer PETT-RIDGE, Paul D. Hoeprich, Eoin Brodie, Peter K. Weber