Abstract: An half shoe includes an upper part, a lower part, an insole part, a bag main part, a first annular elastic part, a covering part, and a second annular elastic part. The insole part, which is attached an upper side surface of the lower part, has elasticity and deodorant effect. The bag main part is constituted by sewing up edges of the upper and lower parts to provide an opening in end part sides of the upper and lower parts. The first annular elastic part is sewn on the opening by the upper part of the bag main part. The covering part is sewn by gathering on the upper part to cover a whole part located in the opening of the first annular elastic part. The second annular elastic part is sewn on the opening by the lower part of the bag main part by gathering.

Abstract: Reagents which regulate human B7-H2 and reagents which bind to human B7-H2 gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, allergic diseases, such as respiratory allergies, food allergies, asthma, and atopic dermatitis, as well as in the treatment of intracellular bacterial infections, such as tuberculosis, leprosy, listeriosis, and salmonellosis; and autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis, and type I diabetes, as well as in the treatment of helminth and extracellular microbial infections.