Patents by Inventor Eric A. Hoffman

Eric A. Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7984453
    Abstract: An availability system is provided that includes a hierarchy of controllers for providing event notifications relating to availability of components of a scalable MPP system. A controller receives a subscription from a child controller that identifies an event type and a generator. The controller stores in a subscription store an indication that the subscription has been received from the child controller. When a parent controller has not yet been notified of a subscription with a matching event type and generator as indicated by the subscription store, the controller sends the subscription to the parent controller. When the parent controller has already been notified of a subscription with a matching event type and generator as indicated by the subscription store, the controller suppresses the sending of the subscription to the parent controller.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: July 19, 2011
    Assignee: Cray Inc.
    Inventors: Gail A. Alverson, Robert L. Alverson, Daniel C. Duval, Eric A. Hoffman, Laurence S. Kaplan, Matthew Kelly, Kazuya Okubo, Mark Swan, Asaph Zemach
  • Publication number: 20110093243
    Abstract: A structural and functional model for a lung or similar organ is virtually defined by encoding aspects of branching passageways. Larger passageways that are visible in medical images are surface mesh fitted to the anatomical surface geometry. Smaller distal passageways, beyond a given number of branch generations, are modeled by inference as linear passages with nominal diameters and branching characteristics, virtually filling the space within the outer envelope of the organ. The model encodes finite volumetric elements for elasticity and compliance in passageway walls, and for local pressure and flow conditions in passageway lumens during respiration. The modeling can assess organ performance, help to plan surgery or therapy, determine likely particle deposition, assess respiratory pharmaceutical dosing, and otherwise represent structural and functional organ parameters.
    Type: Application
    Filed: November 11, 2008
    Publication date: April 21, 2011
    Inventors: Merryn H. Tawhai, Eric A. Hoffman, Ching-Long Lin
  • Patent number: 7885438
    Abstract: A method for automated analysis of textural differences present on an image volume. The image volume includes a plurality of volume elements, and each volume element has a gray level. The method includes defining a volume of interest (VOI); performing texture measures within the VOI; and classifying the VOI as belonging to a tissue pathology class based upon the texture measures. Computer readable media encoded with computer readable instructions for carrying out these functions. An apparatus that includes an image input adapted to receive a diagnostic medical image. The image includes a plurality of pixels, and each pixel has a particular gray level. The apparatus also includes a display for displaying a graphical user interface and the received image; and a processor adapted to perform texture measures on one or more groups of pixels within the image and classify each group of pixels to a tissue pathology class based upon the textures measures.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: February 8, 2011
    Assignee: The University of Iowa Research Foundation
    Inventors: Renuka Uppaluri, Theophano Mitsa, Eric A. Hoffman, Geoffrey McLennan, Milan Sonka
  • Publication number: 20100252627
    Abstract: The present invention is a method for real-time location monitoring of a sterilizable object. The method includes tracking a location of a sterilizable object bearing a tag. The tag includes a sealed housing, means for detecting a sterilization event and means for transmitting data concerning the sterilization event. The method also includes detecting a sterilization event. The method also includes transmitting a signal that the sterilization event has been detected by the tag.
    Type: Application
    Filed: June 14, 2009
    Publication date: October 7, 2010
    Applicant: AWAREPOINT CORPORATION
    Inventors: Matthew R. Perkins, Eric Hoffman, Robert Shein
  • Patent number: 7785568
    Abstract: Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided. Example pharmaceutical compositions of such liposomes, when administered to a subject, provide for increased contrast of extended duration, as measured by computed tomography, in the bloodstream and other tissues of the subject. Also provided are example methods for making the liposomes containing high concentrations of contrast-enhancing agents, and example methods for using the compositions.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: August 31, 2010
    Assignee: Marval Biosciences, Inc.
    Inventors: Ananth Annapragada, Ravi V. Bellamkonda, Eric Hoffman, Chandra Vijayalakshmi
  • Publication number: 20100156921
    Abstract: In one embodiment, a method that includes comparing a subject color medical image to normal color medical image data; and identifying abnormal pixels from the subject color medical image. Another embodiment includes a computer readable medium comprising machine readable instructions for implementing one or more steps of that method. Another embodiment includes a device that has a field programmable gate array configured to perform one or more of the steps of that method. Another embodiment includes a device that has an application specific integrated circuit configured to perform one or more of the steps of that method.
    Type: Application
    Filed: November 3, 2009
    Publication date: June 24, 2010
    Inventors: Geoffrey McLennan, Martin Donnelley, Deepa Gopalakrishnan, Eric Hoffman, Joseph Reinhardt, Melissa Suter
  • Patent number: 7713517
    Abstract: Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided. Example pharmaceutical compositions of such liposomes, when administered to a subject, provide for increased contrast of extended duration, as measured by computed tomography, in the bloodstream and other tissues of the subject. Also provided are example methods for making the liposomes containing high concentrations of contrast-enhancing agents, and example methods for using the compositions.
    Type: Grant
    Filed: April 21, 2004
    Date of Patent: May 11, 2010
    Assignee: Marval Biosciences, Inc.
    Inventors: Ananth Annapragada, Ravi V. Bellamkonda, Eric Hoffman, Chandra Vijayalakshmi
  • Patent number: 7701334
    Abstract: The present invention is a method for real-time location monitoring of a sterilizable object. The method includes tracking a location of a sterilizable object bearing a tag using a mesh network. The tag preferably includes a sealed housing, means for detecting a sterilization event and means for transmitting data concerning the sterilization event. The method also includes detecting a sterilization event. The method also includes transmitting a signal that the sterilization event has been detected by the tag.
    Type: Grant
    Filed: December 20, 2009
    Date of Patent: April 20, 2010
    Assignee: Awarepoint Corporation
    Inventors: Matthew R. Perkins, Eric Hoffman, Robert Shein
  • Publication number: 20100087408
    Abstract: The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-?B for the treatment or prevention of muscular wasting disease, including muscular dystrophy.
    Type: Application
    Filed: May 28, 2009
    Publication date: April 8, 2010
    Applicant: VALIDUS GENETICS
    Inventors: John M. McCall, Eric Hoffman, Kanneboyina Nagaraju
  • Patent number: 7613335
    Abstract: In one embodiment, a method that includes comparing a subject color medical image to normal color medical image data; and identifying abnormal pixels from the subject color medical image. Another embodiment includes a computer readable medium comprising machine readable instructions for implementing one or more steps of that method. Another embodiment includes a device that has a field programmable gate array configured to perform one or more of the steps of that method. Another embodiment includes a device that has an application specific integrated circuit configured to perform one or more of the steps of that method.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: November 3, 2009
    Assignee: The University of Iowa Research Foundation
    Inventors: Geoffrey McLennan, Martin Donnelley, Deepa Gopalakrishnan, Eric Hoffman, Joseph Reinhardt, Melissa Suter
  • Publication number: 20090034040
    Abstract: A directing apparatus having a mechanism for producing steerable energy and a scanning mechanism for scanning the energy.
    Type: Application
    Filed: April 24, 2008
    Publication date: February 5, 2009
    Inventors: Ryan M. Sullivan, Eric Hoffman, William Darin Ingimarson
  • Publication number: 20080131369
    Abstract: Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided. Example pharmaceutical compositions of such liposomes, when administered to a subject, provide for increased contrast of extended duration, as measured by computed tomography, in the bloodstream and other tissues of the subject. Also provided are example methods for making the liposomes containing high concentrations of contrast-enhancing agents, and example methods for using the compositions.
    Type: Application
    Filed: January 12, 2005
    Publication date: June 5, 2008
    Applicant: MARVEL THERAPEUTICS
    Inventors: Ananth Annapragada, Ravi V. Bellamkonda, Eric Hoffman, Chandra Vijayalakshmi, Chen-Yu Kao, Ketan Ghaghada
  • Publication number: 20080134213
    Abstract: An availability system is provided that includes a hierarchy of controllers for providing event notifications relating to availability of components of a scalable MPP system. A controller receives a subscription from a child controller that identifies an event type and a generator. The controller stores in a subscription store an indication that the subscription has been received from the child controller. When a parent controller has not yet been notified of a subscription with a matching event type and generator as indicated by the subscription store, the controller sends the subscription to the parent controller. When the parent controller has already been notified of a subscription with a matching event type and generator as indicated by the subscription store, the controller suppresses the sending of the subscription to the parent controller.
    Type: Application
    Filed: September 18, 2007
    Publication date: June 5, 2008
    Inventors: Gail A. Alverson, Robert L. Alverson, Daniel C. Duval, Eric A. Hoffman, Laurence S. Kaplan, Matthew Kelly, Kazuya Okubo, Mark Swan, Asaph Zemach
  • Patent number: 7365891
    Abstract: A directing apparatus includes a mechanism for producing steerable energy. The apparatus includes a mechanism for steering energy from the producing mechanism while the producing mechanism is stationary. The steering mechanism is in communication with the producing mechanism. The steering mechanism includes a scanning mechanism which continuously in a first direction scans the volume of a surrounding vertically and horizontally. A directing method.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: April 29, 2008
    Assignee: Quantapoint, Inc.
    Inventors: Eric Hoffman, William Darin Ingimarson, Ryan M. Sullivan
  • Publication number: 20070212303
    Abstract: Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided. Example pharmaceutical compositions of such liposomes, when administered to a subject, provide for increased contrast of extended duration, as measured by computed tomography, in the bloodstream and other tissues of the subject. Also provided are example methods for making the liposomes containing high concentrations of contrast-enhancing agents, and example methods for using the compositions.
    Type: Application
    Filed: November 10, 2006
    Publication date: September 13, 2007
    Inventors: Ananth Annapragada, Ravi Bellamkonda, Eric Hoffman, Chandra Vijayalakshmi
  • Publication number: 20070185673
    Abstract: An apparatus and method for calibrating a sensor signal conditioner coupled to a bridge sensor disclosed. The signal conditioner sensor preferably includes a CMOS integrated circuit, which enables relatively easy and precise calibration of resistive bridge sensors via an EEPROM without the use of a microprocessor. When mated to a resistive bridge sensor, the sensor interface can digitally calibrate offset and gain with the option to calibrate offset and gain coefficients and linearity over temperature. A second order compensation can be enabled for temperature coefficients of gain or offset or bridge linearity.
    Type: Application
    Filed: January 9, 2007
    Publication date: August 9, 2007
    Inventors: David Hubanks, Eric Hoffman, Frank Cooper
  • Publication number: 20070111217
    Abstract: Caucasian males, but not females, presenting with statistically significant increases of L162V allelic SNP of the PPAR? gene, relative to that of wild-type homozygotes, have an increased likelihood of increased regional adiposity (subcutaneous fat) and BMI, and are more likely to develop diseases associated with such changes, such as type 2 diabetes and metabolic syndrome.
    Type: Application
    Filed: November 14, 2005
    Publication date: May 17, 2007
    Inventors: Julieta Uthurralt, Heather Gordish-Dressman, Eric Hoffman, Joseph Devaney
  • Publication number: 20070092864
    Abstract: Treatment planning methods, devices and systems. One of the treatment planning methods includes displaying at least a portion of a set of lungs and one or more potential treatment regions; receiving a selection of a target treatment region from among the one or more potential treatment regions; and displaying one or more locations within the portion that are therapeutically linked to the target treatment region. Other treatment planning methods, devices and systems are included.
    Type: Application
    Filed: October 2, 2006
    Publication date: April 26, 2007
    Inventors: Joseph Reinhardt, John Garber, Juerg Tschirren, Milan Sonka, Geoffrey McLennan, Eric Hoffman
  • Publication number: 20070053562
    Abstract: Automated methods for segmenting and smoothing volumes of interest, such as the mediastinal boundary of a lung. Devices and systems configured to perform the automated methods.
    Type: Application
    Filed: February 14, 2006
    Publication date: March 8, 2007
    Inventors: Joseph Reinhardt, Milan Sonka, Geoffrey McLennan, Eric Hoffman, Soumik Ukil
  • Patent number: 7180072
    Abstract: An apparatus for creating a registration network of a scene includes a laser scanner for scanning the scene and obtaining data of the scene. The apparatus includes a plurality of targets placed in the scene. The apparatus includes a mechanism for forming a registration network using only the laser scanner data. A method for creating a registration network of the scene.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: February 20, 2007
    Assignee: Quantapoint, Inc.
    Inventors: Fred M. Persi, Eric Hoffman