Patents by Inventor Eric Altermann

Eric Altermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CELL SURFACE PROTEIN HOMOLOGUES AND USES THEREFORE
    Publication number: 20120149590
    Abstract: Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: November 19, 2007
    Publication date: June 14, 2012
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, B. Logan Buck, W. Michael Russell
  • nucleic acids and uses thereof
    Patent number: 7981651
    Abstract: Lactobacillus acidophilus NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: July 19, 2011
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, Andrea Azcarate-Peril
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE
    Publication number: 20110151053
    Abstract: Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: January 20, 2011
    Publication date: June 23, 2011
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, W. Michael Russell
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR
    Publication number: 20110081707
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 7, 2011
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, Rodolphe Barrangou, W. Michael Russell, Tri Duong
  • nucleic acid sequences encoding protease homologues and uses therefore
    Patent number: 7897367
    Abstract: Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: October 15, 2008
    Date of Patent: March 1, 2011
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, W. Michael Russell
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE
    Publication number: 20110020900
    Abstract: Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: October 15, 2008
    Publication date: January 27, 2011
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, W. Michael Russell
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF
    Publication number: 20110008292
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: September 23, 2010
    Publication date: January 13, 2011
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann
  • NUCLEIC ACIDS ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR
    Publication number: 20100279349
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: April 30, 2010
    Publication date: November 4, 2010
    Applicant: NORTH CAROLINA STATE UNIVERSITY
    Inventors: TODD R. KLAENHAMMER, WILLIAM M. RUSSELL, ERIC ALTERMANN, ANDREA AZCARATE-PERIL
  • Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof
    Patent number: 7824894
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: November 2, 2010
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann
  • Nucleic acid encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
    Patent number: 7754868
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: March 11, 2008
    Date of Patent: July 13, 2010
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, William M. Russell, Eric Altermann, Andrea Azcarate-Peril
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING STRESS-RELATED PROTEINS AND USES THEREFOR
    Publication number: 20100028945
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: August 19, 2009
    Publication date: February 4, 2010
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, M. Andrea Azcarate-Peril, Olivia McAuliffe, W. Michael Russell
  • nucleic acid sequences encoding stress-related proteins and uses therefor
    Patent number: 7608700
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: October 27, 2009
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, M. Andrea Azcarate-Peril, Olivia McAuliffe, W. Michael Russell
  • Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
    Patent number: 7550576
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: June 23, 2009
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, William M. Russell, Eric Altermann, Andrea Azcarate-Peril
  • COMPOSITIONS COMPRISING PROMOTER SEQUENCES AND METHODS OF USE
    Publication number: 20090155913
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Application
    Filed: October 29, 2008
    Publication date: June 18, 2009
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd R. Klaenhammer
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20090155213
    Abstract: Lactobacillus acidophilus NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.
    Type: Application
    Filed: October 17, 2008
    Publication date: June 18, 2009
    Applicant: North Carolina State University
    Inventors: Andrea Azcarate-Peril, Eric Altermann, Todd Klaenhammer
  • nucleic acid sequences encoding cell surface protein homologues and uses therefore
    Patent number: 7538209
    Abstract: Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Grant
    Filed: February 1, 2007
    Date of Patent: May 26, 2009
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, W. Michael Russell, Eric Altermann, B. Logan Buck
  • nucleic acid sequences encoding cell surface protein homologues and uses therefore
    Patent number: 7534876
    Abstract: Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Grant
    Filed: February 1, 2007
    Date of Patent: May 19, 2009
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, W. Michael Russell, Eric Altermann, B. Logan Buck
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CARBOHYDRATE UTILIZATION-RELATED PROTEINS AND USES THEREFOR
    Publication number: 20090093021
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: October 22, 2008
    Publication date: April 9, 2009
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, Rodolphe Barrangou, W. Michael Russell, Tri Duong
  • Compositions comprising promoter sequences and methods of use
    Patent number: 7495092
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: February 24, 2009
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd R. Klaenhammer
  • LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF
    Publication number: 20090005311
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: July 2, 2008
    Publication date: January 1, 2009
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann