Patents by Inventor Eric Altermann

Eric Altermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • nucleic acids and uses thereof
    Patent number: 7468182
    Abstract: Lactobacillus acidophilus NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: December 23, 2008
    Assignee: North Carolina State University
    Inventors: Todd Klaenhammer, Andrea Azcarate-Peril, Eric Altermann
  • nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor
    Patent number: 7459289
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: December 2, 2008
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, Rodolphe Barrangou, W. Michael Russell, Tri Duong
  • nucleic acid sequences encoding protease homologues and uses therefore
    Patent number: 7455992
    Abstract: Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Grant
    Filed: February 22, 2005
    Date of Patent: November 25, 2008
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, W. Michael Russell
  • NUCLEIC ACID ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR
    Publication number: 20080233615
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: March 11, 2008
    Publication date: September 25, 2008
    Applicant: North Carolina State University
    Inventors: Todd R. Klaenhammer, William M. Russell, Eric Altermann
  • nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof
    Patent number: 7407787
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Grant
    Filed: June 22, 2004
    Date of Patent: August 5, 2008
    Assignee: North Carolina State University
    Inventors: Rodolphe Barrangou, Todd R. Klaenhammer, Eric Altermann
  • nucleic acid sequences encoding cell surface protein homologues and uses therefore
    Patent number: 7348420
    Abstract: Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: March 25, 2008
    Assignee: North Carolina State University
    Inventors: Todd R. Klaenhammer, Eric Altermann, B. Logan Buck, W. Michael Russell
  • Lactobacillus acidophillus nucleic acid sequences encoding cell surface protein homologues and uses therefore
    Publication number: 20070258955
    Abstract: Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: February 1, 2007
    Publication date: November 8, 2007
    Applicant: North Carolina State University
    Inventors: Todd Klaenhammer, Eric Altermann, B. Buck, W. Russell
  • Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore
    Publication number: 20070172495
    Abstract: Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: February 1, 2007
    Publication date: July 26, 2007
    Applicant: North Carolina State University
    Inventors: Todd Klaenhammer, Eric Altermann, B. Buck, W. Michael Russell
  • Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore
    Publication number: 20070003667
    Abstract: Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and anti-protease-like antibodies are encompassed. The invention also provides vectors containing a nucleic acid molecule of the invention and cells into which the vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: February 22, 2005
    Publication date: January 4, 2007
    Inventors: Todd Klaenhammer, Eric Altermann, W. Russell
  • Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor
    Publication number: 20070003668
    Abstract: Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate utilization-related and multidrug transporter fusion proteins, antigenic peptides, and anti-carbohydrate utilization-related and anti-multidrug transporter antibodies are encompassed. The invention also provides vectors containing a nucleic acid of the invention and cells into which the vector has been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: March 7, 2005
    Publication date: January 4, 2007
    Inventors: Todd Klaenhammer, Eric Altermann, Rodolphe Barrangou, W. Russell, Tri Duong
  • Methods and compositions to modulate adhesion and stress tolerance in bacteria
    Publication number: 20060269998
    Abstract: Methods and compositions are provided which improve the adhesion of a bacteria to target substrates and/or improve the stress tolerance of a bacteria. Methods comprise exposing bacteria to adhesion adaptive conditions and thereby increasing the adhesion activity and/or stress tolerance of the bacteria. Further provided are bacteria having a modulated production of autoinducer-2. Compositions include recombinant bacteria expressing nucleic acid molecules involved in the pathway of autoinducer-2 production. Further provided are autoinducer-2-related fusion proteins, antigenic peptides, antibodies, and vectors. Methods of screening compounds or environmental conditions which will stimulate the production of autoinducer-2 and/or produce an adhesion adaptive response are further provided, as are various methods of use for the bacteria having increased adhesion and/or stress tolerance.
    Type: Application
    Filed: April 14, 2006
    Publication date: November 30, 2006
    Applicant: North Carolina State University
    Inventors: B. Logan Buck, M. Andrea Azcarate-Peril, Eric Altermann, Todd Klaenhammer
  • Compositions comprising promoter sequences and methods of use
    Publication number: 20060166323
    Abstract: Nucleic acid molecules, fragments and variants thereof having promoter activity are provided in the current invention. The invention also provides vectors containing a nucleic acid molecule of the invention and cells comprising the vectors. Methods for making and using the nucleic acid molecules of the invention are further provided.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 27, 2006
    Applicant: North Carolina State University
    Inventors: Rodolphe Barrangou, Andrea Azcarate-Peril, Eric Altermann, Tri Duong, Todd Klaenhammer
  • Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
    Publication number: 20060134745
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: August 8, 2005
    Publication date: June 22, 2006
    Applicant: North Carolina State University
    Inventors: Todd Klaenhammer, William Russell, Eric Altermann
  • Lactobacillus acidophilus nucleic acids and uses thereof
    Publication number: 20060121571
    Abstract: Lactobacillus acidophilus NCFM nucleic acid molecules, polypeptides, fragments and variants thereof are provided in the current invention. In addition, fusion proteins, antigenic peptides, and antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells comprising the expression vectors. Methods for producing the polypeptides of the invention and methods for their use are further provided.
    Type: Application
    Filed: October 27, 2005
    Publication date: June 8, 2006
    Applicant: North Carolina State University
    Inventors: Todd Klaenhammer, William Russell, Eric Altermann
  • Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
    Publication number: 20050250135
    Abstract: Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed.
    Type: Application
    Filed: March 7, 2005
    Publication date: November 10, 2005
    Inventors: Todd Klaenhammer, Eric Altermann, M. Azcarate-Peril, Olivia McAuliffe, W. Russell
  • Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof
    Publication number: 20050123941
    Abstract: Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion proteins, antigenic peptides, and anti-FOS-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed.
    Type: Application
    Filed: June 22, 2004
    Publication date: June 9, 2005
    Inventors: Rodolphe Barrangou, Todd Klaenhammer, Eric Altermann