Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

Abstract: In non-limiting examples of the present disclosure, systems, methods and devices for generating searchable data structures using observational context data are provided. An indication to process observational context data surfaced by a local computing device may be received. The observational context data may comprise display data or audio data. The observational context data may be processed by a context analysis engine. A determination may be made of a current context type occurring on the local computing device. The current context type may be determined from a plurality of context types, each having a semantic data structure comprising a unique set of entity types. A canvas comprising a searchable data structure of the current context type may be generated and populated with objects having entity types corresponding to the current context type. A displayable representation of the canvas may be displayed.

Abstract: Described systems and techniques determine a password change trigger for a password for an account, and access a connection store storing a plurality of password models. Each password model may include at least one password requirement and at least one password change procedure. Based on the password change trigger and from the plurality of password models, a selected password model for the password and the account may be selected. The account may be accessed using at least one selected password change procedure of the selected password model, and the password may be updated in accordance with at least one selected password requirement of the selected password model.

Abstract: An event deduplication system may efficiently perform event deduplication (identifying “new” or “unique” events that might be an anomaly) by using a first stage that has multiple first stage processes running in parallel (e.g., at different data centers) and a single second stage that has a second stage process that receives and processes events from the different first stage processes. The second stage process updates a global state (e.g., lookup table) and periodically publishes the global state to the first stage processes to update their local state. When the second stage process receives a possible new event from a first stage process, it may more accurately determine whether the event is actually a new event based on the global state.

Abstract: The present disclosure is directed to a polymeric layer comprising a catechol containing a monomer, polymer, or oligomer, wherein said catechol presents as a catechol and/or as a semi-quinone and/or as a quinone without the presence of a primary amine or a secondary amine; and wherein the polymeric layer optionally comprises a reactive material that is not reactive with catechol or quinone. The present disclosure is also directed to a polymeric layer comprising a catechol containing monomer, polymer, or oligomer disposed adjacent to and in contact with a bulk adhesive layer. The present disclosure is also directed to methods of coating a substrate using the layers described herein.

Abstract: A device for generating archival notes for a user based on content a user has located electronically and viewed on a display device includes: a display for presenting information to a user, a user interface for receiving user input from the user; a processor; and a memory storing executable instructions which, when executed by the processor, cause the processor, alone or in combination with other processors, to perform the following: capturing information on the display; operating a prompt generator to structure a prompt for a generative Artificial Intelligence (AI) model, the prompt based on the information captured from the display and causing the AI model to generate a note based on the information captured; and storing the note in a user data structure for future reference by the user.

Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.

Abstract: An event deduplication system may efficiently perform event deduplication (identifying “new” or “unique” events that might be an anomaly) by using a first stage that has multiple first stage processes running in parallel (e.g., at different data centers) and a single second stage that has a second stage process that receives and processes events from the different first stage processes. The second stage process updates a global state (e.g., lookup table) and periodically publishes the global state to the first stage processes to update their local state. When the second stage process receives a possible new event from a first stage process, it may more accurately determine whether the event is actually a new event based on the global state.

Abstract: Devices, systems, and their methods of use for droplet generation are provided. The devices, systems, and their methods have a droplet source region that is coated with a fluoropolymer silane coating agent that provides a surface coating having a total fluorine weight percent of at least 57%.

Abstract: Conventional dental cements lack certain properties such as the facilitation of optimal re-mineral-ization. The novel bioactive glass-ionomer dental and bone cement formulations disclosed herein induces mineralization at the in vivo interface and exhibits superior handling properties (shorter setting time) and mechanical properties (improved bond strength to dentin and flexural strength). The present invention presents the first bioactive glass-ionomer dental cement with mineralization power, exhibiting improved bond strength to tooth structure, sharp setting time and superior me-chanical strength.

Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

Abstract: An exterior wall panel assembly may include a metal stud wall panel frame including a bottom track, a top plate, vertically extending studs between the bottom track and the top plate, and a window opening. An assembly may include an exterior sheathing formed from panels of sheathing. An assembly may include a window assembly, the window assembly installed within the window opening. An assembly may include a sealant applied between the panels of sheathing, between the exterior sheathing and the window assembly, and along the side edges and the top edge of the exterior sheathing. An assembly may include a support ledge positioned at the top of the wall panel and connected to a pour stop. An assembly may include a lintel positioned above the window opening, the lintel connected to the frame.

Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.

Abstract: Crosslinked fluorocarbon surface coating, kits therefor, microfluidic devices having crosslinked fluoropolymer surface coatings, and methods of use for droplet generation are provided. The kits, devices, and their methods have a droplet source region that is coated with a crosslinked fluoropolymer surface coating produced by the reaction of a fluorocarbon silane and a fluorocarbon polyol.

Abstract: Devices and methods are provided for reducing or removing condensation from compressed air.

Abstract: Disclosed herein are solvent reservoir systems for steady flow delivery and simultaneous monitoring of solvent level and solvent density within the solvent reservoir systems and methods for monitoring the solvent reservoir systems and providing feedback to a user or adjusting the systems in response to the monitored characteristics.

Abstract: Disclosed is a gradient proportioning valve for liquid chromatography that includes a plurality of inlet ports configured to receive a plurality of fluids, a manifold connected to each of the plurality of inlet ports configured to mix the plurality of fluids in a controlled manner to provide a fluid composition, the manifold including a plurality of conduits internal to the manifold, each of the plurality of conduits receiving fluid through a respective one of the plurality of inlet ports, an actuation mechanism having a piston located within a bored structure surrounding the piston, the actuation mechanism configured to open and close at least one of the plurality of conduits in a controlled manner where the piston and the bored structure have a tight tolerance configured to create a fluid tight seal, and a common outlet port configured to receive the fluid composition.