Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, are disclosed. A system performs operations including receiving sensor data from a sensor of a property monitored by a monitoring system, and based on the sensor data, determining a first event and a second event that have occurred at the property. The operations include determining that the monitoring system is not able to communicate with an outside network, and classifying the first event as a high priority event and the second event as a low priority event. The operations include determining that a mobile device is able to receive data from the monitoring system; and providing, to the mobile device, data indicating the first event and an instruction to transmit the data indicating the first event to a server upon the mobile device being able to communicate with the outside network.

Abstract: A pipe cutter comprises a main body, a clamping assembly and a cutting blade. The main body has a first gripping member and a second gripping member. The clamping assembly has a first clamping arm and a second clamping arm pivotally disposed side by side in the guide groove of the first gripping member, the first clamping arm and the second clamping arm being rotatable relative to each other under external force so as to vary a clamping angle therebetween. The cutting blade is fixed to the main body. A cutting space is defined between the cutting blade and the clamping assembly for receiving a pipe. Wherein when the cutting blade applies a force to the pipe located in the cutting space, the first clamping arm and the second clamping arm of the clamping assembly rotate toward each other so as to cooperatively clamp an outer surface of the pipe.

Abstract: The present disclosure provides anti-albumin constructs each comprising an antialbumin single-domain antibody (sdAb) moiety. The anti-albumin constructs can further comprise a therapeutic agent, such as an antigen binding moiety or a cytokine. The present disclosure also provides methods of making and using the anti-albumin constructs.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage mediums, for a smartlock device that can be integrated in a door at a property. The smartlock device includes a locking mechanism configured to lock the door and to unlock the door. The device includes a radio device and a sensor that determines a first temperature of the smartlock device and a second temperature of a room that is accessible via the door. The radio device is operable to: i) receive parameter signals from the sensor indicating each of the first and second temperatures; ii) transmit data that includes the first and second temperatures to a monitoring system; and iii) receive a command to cause the locking mechanism to unlock the door based on information from the monitoring system. The information includes a determined routing of occupants at the property and is presented on a display of the device.

Abstract: The present application provides fusion proteins that comprise a cytokine fused to an albumin binding moiety. The fusion proteins may further comprise an antigen binding moiety such as a therapeutic antibody. The present application also provides methods of making and using the fusion proteins. The present application also provides methods of treatment comprises administering a fusion protein comprising a cytokine fused to a half-life extending domain and a second agent.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for adjusting an adjustable textile based on sensor data. The methods, systems, and apparatus include actions of receiving sensor data from one or more sensors installed at a property, generating an analysis result by analyzing the sensor data, and determining, based on the analysis result, an action that adjusts an inflation level of an adjustable textile at the property.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, are disclosed. A system performs operations including receiving sensor data from a sensor of a property monitored by a monitoring system, and based on the sensor data, determining a first event and a second event that have occurred at the property. The operations include determining that the monitoring system is not able to communicate with an outside network, and classifying the first event as a high priority event and the second event as a low priority event. The operations include determining that a mobile device is able to receive data from the monitoring system; and providing, to the mobile device, data indicating the first event and an instruction to transmit the data indicating the first event to a server upon the mobile device being able to communicate with the outside network.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, are disclosed. A system performs operations including receiving sensor data from a sensor of a property monitored by a monitoring system, and based on the sensor data, determining a first event and a second event that have occurred at the property. The operations include determining that the monitoring system is not able to communicate with an outside network, and classifying the first event as a high priority event and the second event as a low priority event. The operations include determining that a mobile device is able to receive data from the monitoring system; and providing, to the mobile device, data indicating the first event and an instruction to transmit the data indicating the first event to a server upon the mobile device being able to communicate with the outside network.

Abstract: A chamfer tool includes a main body, a driving shaft and a plurality of milling members. The main body, which rotates along an axis, has an inner surface and an outer surface located on opposite sides thereof; wherein the main body further has a plurality of mounting portions, each of which is connected to the inner surface and outer surface. The driving shaft is fixed to the main body to drive the main body to rotate. Each of the milling members has a first blade and a second blade, wherein the milling members are mounted on the mounting portions of the main body with the first blades protruding from the outer surface of the main body and the second blades protruding from the inner surface of the main body.

Abstract: Provided herein are an interleukin-2 polypeptide and a fusion protein thereof. Also provided herein are their pharmaceutical compositions and methods of use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage mediums, for a smartlock device that can be integrated in a door at a property. The smartlock device includes a locking mechanism configured to lock the door and to unlock the door. The device includes a radio device and a sensor that determines a first temperature of the smartlock device and a second temperature of a room that is accessible via the door. The radio device is operable to: i) receive parameter signals from the sensor indicating each of the first and second temperatures; ii) transmit data that includes the first and second temperatures to a monitoring system; and iii) receive a command to cause the locking mechanism to unlock the door based on information from the monitoring system. The information includes a determined routing of occupants at the property and is presented on a display of the device.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage mediums, for a smartlock device that can be integrated in a door at a property. The smartlock device includes a locking mechanism configured to lock the door and to unlock the door. The device includes a radio device and a sensor that determines a first temperature of the smartlock device and a second temperature of a room that is accessible via the door. The radio device is operable to: i) receive parameter signals from the sensor indicating each of the first and second temperatures; ii) transmit data that includes the first and second temperatures to a monitoring system; and iii) receive a command to cause the locking mechanism to unlock the door based on information from the monitoring system. The information includes a determined routing of occupants at the property and is presented on a display of the device.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, are disclosed. A system performs operations including receiving sensor data from a sensor of a property monitored by a monitoring system, and based on the sensor data, determining a first event and a second event that have occurred at the property. The operations include determining that the monitoring system is not able to communicate with an outside network, and classifying the first event as a high priority event and the second event as a low priority event. The operations include determining that a mobile device is able to receive data from the monitoring system; and providing, to the mobile device, data indicating the first event and an instruction to transmit the data indicating the first event to a server upon the mobile device being able to communicate with the outside network.

Abstract: The present disclosure provides anti-albumin constructs each comprising an antialbumin single-domain antibody (sdAb) moiety. The anti-albumin constructs can further comprise a therapeutic agent, such as an antigen binding moiety or a cytokine. The present disclosure also provides methods of making and using the anti-albumin constructs.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, are disclosed. A system performs operations including receiving sensor data from a sensor of a property monitored by a monitoring system, and based on the sensor data, determining a first event and a second event that have occurred at the property. The operations include determining that the monitoring system is not able to communicate with an outside network, and classifying the first event as a high priority event and the second event as a low priority event. The operations include determining that a mobile device is able to receive data from the monitoring system; and providing, to the mobile device, data indicating the first event and an instruction to transmit the data indicating the first event to a server upon the mobile device being able to communicate with the outside network.

Abstract: Provided herein are an interleukin-2 polypeptide and a fusion protein thereof. Also provided herein are their pharmaceutical compositions and methods of use for treating, preventing, or ameliorating one or more symptoms of a proliferative disease.

Abstract: The present application provides fusion proteins that comprise a cytokine fused to an albumin binding moiety. The fusion proteins may further comprise an antigen binding moiety such as a therapeutic antibody. The present application also provides methods of making and using the fusion proteins. The present application also provides methods of treatment comprises administering a fusion protein comprising a cytokine fused to a half-life extending domain and a second agent.