Abstract: The present invention relates to immunogenic compositions comprising recombinantly constructed polypeptides useful for preparing vaccines, in particular for reducing one or more clinical signs caused by a rotavirus infection. More particular, the present invention is directed to an immunogenic composition containing (i) a fusion protein comprising in N- to C-terminal direction (A) an immunogenic fragment of a rotavirus VP8 protein and (B) an immunoglobulin Fc fragment such as, for example, an IgG Fc fragment, and (ii) an immunogenic substance, different from said fusion protein, wherein said immunogenic composition is usable in a method of reducing one or more clinical signs, mortality or fecal shedding caused by a rotavirus infection in swine.

Abstract: Various embodiments provide apparatuses, systems, and methods related to a dual-sided optical package. The package may include a base plate with a first side and a second side opposite the first side. The base plate may have a coolant channel positioned between the first side and the second side. A first set of optics may be coupled with the first side of the base plate, and a second set of optics may be coupled with the second side of the base plate. Other embodiments may be described and/or claimed.

Abstract: A modular material tracking system is provided for tracking material stored on and drawn from a reel using a modular system. The modular material tracking system may include a detection element, digital logic components, location receiver, enclosure, analytic components, interface component, sensor module, and plate module. One or more sensors relative to the reel may detect a position indicative of forward or reverse reel rotation. A processor may analyze signals to count rotations of the reel, which is savable in memory. A battery may provide power. The system may also record the time and location associated with rotations. A method for tracking material stored on and drawn from a reel using a modular material tracking system is also provided.

Abstract: The present invention relates to recombinantly constructed proteins useful for analytical assays, in particular for determining in a biological sample obtained from an individual the presence of antibodies specific for a rhabdovirus. More particular, the present invention relates to a polypeptide comprising an ectodomain of a rhabdovirus glycoprotein and a heterologous multimerization domain linked to said ectodomain. In one example, a fusion protein of the formula x-y-z is provided, wherein x consists of or comprises such an ectodomain being optionally free of a furin cleavage site, y is a linker moiety, and z is a heterologous multimerization domain optionally selected from the group consisting of immunoglobulin sequence, coiled coil sequence, streptavidin sequence, fibritin sequence, and avidin sequence.

Abstract: Vaccination methods to control PCV2 infection with different PCV2 subtypes are disclosed. Specifically, a PCV2 subtype b (PCV2b) ORF2 proteins or immunogenic compositions comprising a PCV2b ORF2 protein are used in a method for the treatment or prevention of an infection with PCV2 of the same PCV2b and/or different subtype; the reduction, prevention or treatment of clinical signs caused by an infection with PCV2 of the same PCV2b or a different subtype; and/or the prevention or treatment of a disease caused by an infection with PCV2 of the same PCV2b and/or a different subtype. The present invention in particular relates to PCV2 subtype b (PCV2b) ORF2 proteins characterized in that they contain at least one mutation in the BC loop that such that the expressed protein is preferably expressed in a higher amount compared to a PCV2 ORF2 protein that does not contain such mutation.

Abstract: Examples include a fluidic die. The fluidic die comprises an array of field effect transistors including field effect transistors of a first size and field effect transistors of a second size. At least one connecting member interconnects at least some of the field effect transistors of the array of field effect transistors. The fluidic die further comprises a first fluid actuator connected to a first set of field effect transistors having at least one field effect transistor of the first size. The die includes a second fluid actuator connected to a second respective set of field effect transistors having a first respective field effect transistor of the second size interconnected to at least one other field effect transistor of the array.

Abstract: A glass hollow container including a finish intended to cooperate with a cap with notches to close the container, wherein the finish has a locking ring whose cross section has a profile substantially in the shape of an ogive.

Abstract: Various embodiments provide apparatuses, systems, and methods related to a heat sink with one or more removable inserts. Respective inserts may include one or more fins that define one or more channels for flow of cooling fluid. The fins may be formed of a composite material that is different than a material of the heat sink body. Other embodiments may be described and/or claimed.

Abstract: An optical component has a bottom part located in an opening defined by a surface, wherein a distance between a sidewall of the bottom part of the optical component and a sidewall of the opening is non-uniform in which a width of a first section of the opening or a first section of the bottom part of the optical component is narrower than a width of a second lower section of the opening or a width of a second lower section of the bottom part of the optical component; and an adhesive is located in the opening between sidewalls.

Abstract: Provided herein are compositions and methods for the treatment of a cancer. Said compositions comprise a RAF inhibitor. Some embodiments comprise combination therapy featuring the RAF inhibitor with at least one oncology therapeutic agent.

Abstract: A method for transferring a spacecraft (10), such as an artificial satellite, from an initial elliptical orbit (30) to a final geostationary orbit (50), the spacecraft taking at least one intermediate elliptical orbit (40) propelled by electric propulsion means (12, 13), the method includes: when the spacecraft is in an intermediate orbit, a nominal thrust step (410) in which the propulsion means generate nominal thrust while the spacecraft is on at least part of a first orbital arc (41) passing through the apogee A of the intermediate orbit, and a minimum thrust step (420), in which the propulsion means are partly stopped or slowed while the spacecraft is on at least part (43) of a second orbital arc (42) passing through the perigee P of the intermediate orbit, the two orbital arcs being complementary.

Abstract: A fluidic die includes fluid chambers, each including an electrode exposed to an interior of the fluid chamber and each having a corresponding fluid actuator operating at a high voltage. The fluidic die further includes monitoring circuitry, operating at a low voltage relative to the fluid actuator, to monitor a condition of each fluid chamber, for each chamber the monitoring circuitry including a connection structure and a select transistor and a pulldown transistor connected to the electrode via the connection structure. The connection structure and select and pulldown transistors together structured to form electrically conductive paths with electrical resistances to protect at least the select transistor from fault damage if the high voltage fluid actuator short-circuits to the electrode.

Abstract: System for tracking and assessing the condition of replaceable refractory elements in a metallurgic facility comprising: a) a plurality of identifiable metallurgical vessels, such as ladles, wherein each one of said identifiable metallurgical vessels comprises removable refractory elements, such as slide gate valve plates; b) a plurality of replacement refractory elements, wherein each replacement refractory element comprises a machine-readable identification tag comprising refractory element identification data; c) a reading station, such as an RFID workbench, for reading the machine-readable identification tags of a replacement refractory element positioned in a reading zone of the reading station; d) a refractory condition tool for assessing the condition of refractory elements coupled to anyone of said metallurgical vessels; e) a monitoring unit connectable to the reading station and the refractory condition tool.

Abstract: Examples include a fluidic die. The fluidic die comprises an array of field effect transistors. Connecting members electrically connect at least some of the field effect transistors of the array of field effect transistors, and the field effect transistors of the array are arranged into respective sets of field effect transistors. The fluidic die further comprises a first fluid actuator connected to a first set of field effect transistors having a first number of field effect transistors. The die includes a second fluid actuator connected to a second respective set of field effect transistors having a second number of field effect transistors that is different than the first number of field effect transistors.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for processing cell images using neural networks. One of the methods includes obtaining data comprising an input image of one or more biological cells illuminated with an optical microscopy technique; processing the data using a stained cell neural network; and processing the one or more stained cell images using a cell characteristic neural network, wherein the cell characteristic neural network has been configured through training to receive the one or more stained cell images and to process the one or more stained cell images to generate a cell characteristic output that characterizes features of the biological cells that are stained in the one or more stained cell images.

Abstract: A cleaning article includes: a first panel having: a first fiber layer; and a first substrate attached to the first fiber layer by a first connection type; and a second panel having: a second fiber layer; and a second substrate attached to the second fiber layer by the first connection type. The first connection type includes a first connection line in parallel with a second connection line, the first and second connection lines together straddling a center line of a respective panel that extends in an axial direction. The first panel is attached to the second panel by a plurality of spot connections so as to create a pocket between the first panel and the second panel.

Abstract: A chair add-on, a chair, a chair modification, a chair hinge, and/or a hinge system that may be used to provide enhanced seating comfort to users. It is preferred, but not necessary, that the chair add-on, the chair, the chair modification, the chair hinge, and/or the hinge system is easy to use by users of all ages.

Abstract: A die for a printhead is provided in examples. The die includes a number of fluidic actuator arrays, proximate to a number of fluid feed holes. A number of address lines are disposed proximate to a number of logic circuits on a low-voltage side of the fluid feed holes. An address decoder circuit is coupled to at least a portion of the address lines to select a fluidic actuator in a fluidic actuator array for firing. The address decoder circuit is customized to select a different address for each fluidic actuator in the fluidic actuator array. A logic circuit triggers a driver circuit located in a high-voltage side of the plurality of fluid feed holes opposite the low-voltage side, based, at least in part, on a bit value for the fluidic actuator array, the fluidic actuator selected by the address decoder circuit, and a firing signal.

Abstract: In one example in accordance with the present disclosure, a fluidic die is described. The fluidic die includes a number of zones. Each zone includes a number of sets of fluidic devices. Each fluidic device includes a fluid chamber and a fluid actuator disposed in the chamber. Each fluidic device also includes a sensor to sense a characteristic of the zone and an adjustment device. The adjustment device 1) delays a firing signal received from a previous zone as it passes by each set of fluidic devices and 2) adjusts the firing signal as it enters the zone based on a sensed characteristic.

Abstract: Provided herein are compositions and methods for the treatment of a triple-negative breast cancer, ovarian cancer and castration-resistant prostate cancer. Said compositions comprise CDK12/13 inhibitors.