Abstract: A pre-filled syringe assembly having a tamper evident tip cap is provided for indicating if the contents of the syringe assembly have been compromised. The syringe barrel has an interior chamber which defines a pressure therein and is sealed at the proximal and distal ends by a first and second seal, respectively, to maintain this pressure. The second seal is formed of a deformable material and a tip cap is located about the second seal and distal end of the syringe barrel. This tip cap includes a viewable indicator representing a change in state of the syringe contents. The indicator has a portion positioned in contact with the second seal such that the first distinguishing feature is viewable through a portion of the cap. Tampering of the contents within the interior chamber causes a change in pressure and movement of the indicator indicating tampering of the syringe assembly.

Abstract: A syringe assembly having a collapsible or pivotable plunger rod with magnification properties is provided. In a pre-use or packaged state, the plunger rod is positioned substantially parallel to the barrel of the syringe resulting in a syringe assembly having a reduced length and a smaller packaging footprint. The smaller packaging footprint allows for reduced storage space of the syringe assembly. Upon removal from the packaging and/or storage space, the plunger rod can be slid or pivoted toward the proximal end of the syringe barrel and locked into place such that the syringe is ready for use. The plunger rod can be shaped to provide magnification to the syringe barrel indicia and/or contents. Alternatively, a separate magnification member can be associated with the plunger rod and/or secured about the syringe barrel.

Abstract: A syringe assembly includes a syringe barrel having an exterior surface, an inside surface defining a chamber, an open proximal end, a distal end, and an outlet disposed adjacent the distal end in fluid communication with the chamber; and a plunger assembly disposed at least partially within the syringe barrel. The plunger assembly includes an elongated plunger rod and a plunger head. The elongated plunger rod is associated with the plunger head to move the plunger head within the chamber of the syringe barrel through an injection cycle. The plunger rod is adapted to move from a collapsed position extending alongside the exterior surface of the syringe barrel to an extended position engaging the plunger head to move the plunger head through the injection cycle.

Abstract: A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to the profile of the syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of the contents of the syringe barrel.

Abstract: The invention provides a syringe assembly comprising a syringe barrel having an inside surface defining a chamber, an open proximal end, and a distal end having an opening therethrough. An elongated plunger rod extends between a first end and a second end, with a cap or guard disposed on the first end of the plunger rod. A plunger head extends within the chamber of the syringe barrel, and is adapted for slidable movement within the syringe barrel between the proximal end and the distal end, with the second end of the plunger rod connected with the plunger head through a pivotable connection. The plunger rod is adapted to pivot with respect to the plunger head between a first position in which the guard is adjacent the distal end of the syringe barrel and a second position in which the plunger rod is in general axial alignment with the syringe barrel, and is further adapted for axial movement so as to cause sliding movement of the plunger head through the syringe barrel to expel the contents thereof.

Abstract: A syringe assembly having a flexible and/or slidable flange is provided, wherein in a pre-use or packaged state, the flange is positioned substantially parallel to the barrel of the syringe resulting in a syringe assembly having a smaller packaging footprint. The smaller packaging footprint allows for reduced storage space of the syringe assembly. Upon removal from the packaging and/or storage space, the flange can be slid and locked into place such that it extends in a perpendicular direction with respect to a longitudinal axis of the syringe barrel to allow for traditional operation of the syringe.

Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.

Abstract: A syringe and detachable needle assembly having binary attachment features include an elongate syringe barrel having a longitudinal axis, an open proximal end and an open distal end including a collar. The collar includes the cylindrically shaped sidewall having an inside surface and an outside surface. A needle assembly includes the hub having a body portion including a proximal end, a distal end and a conduit therethrough. A cannula having a distal end, a proximal end and a lumen therethrough is attached to the distal end of the hub so that the lumen is in fluid communication with the chamber. A lug is provided on one of the collar and the hub and a ramp and a rest surface is provided on the other of the collar and the hub. The ramp is oriented at an acute angle with respect to longitudinal axis for guiding the lug during needle assembly attachment, to the rest surface forcing the hub to contact the barrel to form a seal the hub and the barrel.

Abstract: A syringe and detachable needle assembly having binary attachment features include an elongate syringe barrel having a longitudinal axis, an open proximal end and an open distal end including a collar. The collar includes the cylindrically shaped sidewall having an inside surface and an outside surface. A needle assembly includes the hub having a body portion including a proximal end, a distal end and a conduit therethrough. A cannula having a distal end, a proximal end and a lumen therethrough is attached to the distal end of the hub so that the lumen is in fluid communication with the chamber. A lug is provided on one of the collar and the hub and a ramp and a rest surface is provided on the other of the collar and the hub. The ramp is oriented at an acute angle with respect to longitudinal axis for guiding the lug during needle assembly attachment, to the rest surface forcing the hub to contact the barrel to form a seal the hub and the barrel.

Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end including a distal wall with an elongate tip extending distally therefrom having a passageway therethrough in fluid communication with the chamber. A plunger having an elongate body portion and a stopper slidably positioned in fluid-tight engagement with the inside surface of the barrel is provided. Anti-reflux structure in said barrel is provided for controlling stopper deflection when fluid has been delivered from the chamber and the stopper is in contact with structure on the distal wall.

Abstract: A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.

Abstract: A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.

Abstract: A medical device for delivering a medicament to a patient. The device includes a syringe barrel assembly having a syringe barrel with a plunger movably insertable therein to expel medicament in the barrel. A needle cannula is connected to a needle cannula hub which is slidably arranged in the barrel for moving between an initial position in which the forward tip is exposed and a retracted position in which the forward tip is contained within the barrel. A retainer engages an annular groove defined in an inner surface of the barrel and secures the needle cannula hub at the initial position proximate the front end of the barrel. An urging member is arranged between the front end of the barrel and the needle cannula hub for urging the needle cannula hub toward the retracted position. The retainer is released in response to the application of medicament delivery force when the stopper is in a fully inserted position.

Abstract: A syringe and detachable needle assembly having reduced dead space features includes an elongate syringe barrel having open distal end including a collar and a distally facing annular surface projecting inwardly from the collar. A needle assembly includes a hub having a proximally facing annular surface and an outwardly projecting annular sealing ring positioned distally from the surface. The needle assembly also includes a cannula having a lumen therethrough connected to the distal end of the hub. Structure is provided for engaging the hub to the barrel resulting in the annular surface of the barrel contacting the annular surface of the hub to form a primary seal between said barrel and said hub and the annular sealing ring contacting the collar to form a secondary seal between the barrel and the hub.

Abstract: A syringe and detachable needle assembly having binary attachment features include an elongate syringe barrel having a longitudinal axis, an open proximal end and an open distal end including a collar. The collar includes the cylindrically shaped sidewall having an inside surface and an outside surface. A needle assembly includes the hub having a body portion including a proximal end, a distal end and a conduit therethrough. A cannula having a distal end, a proximal end and a lumen therethrough is attached to the distal end of the hub so that the lumen is in fluid communication with the chamber. A lug is provided on one of the collar and the hub and a ramp and a rest surface is provided on the other of the collar and the hub. The ramp is oriented at an acute angle with respect to longitudinal axis for guiding the lug during needle assembly attachment, to the rest surface forcing the hub to contact the barrel to form a seal the hub and the barrel.

Abstract: A medical device for delivering a medicament to a patient. The device includes a syringe barrel assembly having a syringe barrel with a plunger movably insertable therein to expel medicament in the barrel. A needle cannula is connected to a needle cannula hub which is slidably arranged in the barrel for moving between an initial position in which the forward tip is exposed and a retracted position in which the forward tip is contained within the barrel. A retainer engages an annular groove defined in an inner surface of the barrel and secures the needle cannula hub at the initial position proximate the front end of the barrel. An urging member is arranged between the front end of the barrel and the needle cannula hub for urging the needle cannula hub toward the retracted position. The retainer is released in response to the application of medicament delivery force when the stopper is in a fully inserted position.

Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end including a distal wall with an elongate tip extending distally therefrom having a passageway therethrough in fluid communication with the chamber. A plunger having an elongate body portion and a stopper slidably positioned in fluid-tight engagement with the inside surface of the barrel is provided. Anti-reflux structure in said barrel is provided for controlling stopper deflection when fluid has been delivered from the chamber and the stopper is in contact with structure on the distal wall.