Abstract: The invention provides a medical device comprising a fluoropolymer surface comprising at least one hyaluronic acid species.

Abstract: The invention provides a medical device comprising a fluoropolymer surface comprising at least one species independently chosen from: a carboxybetaine, a sulfobetaine, and combinations and/or polymers thereof.

Abstract: Machine learning systems and methods for multiscale Alzheimer's dementia recognition through spontaneous speech are provided. The system retrieves one or more audio samples and processes the one or more audio samples to extract acoustic features from audio samples. The system further processes the one or more audio samples to extract linguistic features from the audio samples. Machine learning is performed on the extracted acoustic and linguistic features, and the system indicates a likelihood of Alzheimer's disease based on output of machine learning performed on the extracted acoustic and linguistic features.

Abstract: Systems and methods for machine learning of voice and other attributes are provided. The system receives input data, isolates predetermined sounds from isolated speech of a speaker of interest, summarizes the features to generate variables that describe the speaker, and generates a predictive model for detecting a desired feature of a person Also provided are systems and methods for detecting one or more attributes of a speaker based on analysis of audio samples or other types of digitally-stored information (e.g, videos, photos, etc.).

Abstract: Systems and methods for machine learning of voice and other attributes are provided. The system receives input data, isolates predetermined sounds from isolated speech of a speaker of interest, summarizes the features to generate variables that describe the speaker, and generates a predictive model for detecting a desired feature of a person Also provided are systems and methods for detecting one or more attributes of a speaker based on analysis of audio samples or other types of digitally-stored information (e.g, videos, photos, etc.).

Abstract: Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

Abstract: Systems, methods, and computer-readable non-transitory storage medium for communicating medical information based at least in part on an oral communication between a doctor and a patient is disclosed. In this method and system, doctor and patient's respective contexts is inferred from the oral communication. It is also preferred that diagnostic information and respective contexts of the communications can be also inferred. Then, a desired impact of a recipient to a written communication related to the oral communication is inferred. Once the desired impact is inferred, the system generates output text using an artificial intelligence system, or by accessing a database of a plurality of stock phrases, to have appropriate surface text, and subtext, and optionally appropriate tone. The output text can be selected as a function of inferred diagnostic information, the inferred doctor and recipient's respective contexts, the desired impact, and the stock phrases.

Abstract: Systems, methods, and computer-readable non-transitory storage medium in which a statistical machine translation model for formatting medical reports is trained in a learning phase using bitexts and in a tuning phase using manually transcribed dictations. Bitexts are generated from automated speech recognition dictations and corresponding formatted reports, using a series of steps including identifying matches and edits between the dictations and their corresponding reports using dynamic programming, merging matches with adjacent edits, calculating a confidence score, identifying acceptable matches, edits, and merged edits, grouping adjacent acceptable matches, edits, and merged edits, and generating a plurality of bitexts each having a predetermined maximum word count (e.g., 100 words), preferably with a predetermined overlap (e.g., two thirds) with another bitext.

Abstract: A method for assisting the transformation of a dictated, into a structured and written, report within a specialized field. The method starts with using automated speed recognition to produce a preliminary textual representation, which it then transforms into a simplified and normalized input sequence, which it copies and then transforms the copy by replacing words with tokens appropriate to the class of word as known, rare, or reducible, thereby creating a tokenized input sequence. The method then identifies and removes any preamble from the narrative text and restores punctuation, before restoring for each token within the tokenized input sequence its separable individual and original word and thus producing punctuated narrative text for processing into the written and structured report.

Abstract: Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

Abstract: Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

Abstract: Disclosed is a microwavable heating element and thermal storage composition for the controlled storage and release of thermal energy to a thermal mass. The microwavable heating element can be used in conjunction with a warming trivet. One disclosed warming trivet includes a housing, a heating element arranged within the housing and made of a matrix material and a microwave susceptor suspended within the matrix material, and an insulation layer disposed between the heating element and the housing, the insulation layer being configured to insulate the housing from thermal energy emitted by the heating element.

Abstract: The present invention provides patterned features of dimensions of less than 50 nm on a substrate. According to various embodiments, the features may be “Manhattan” style structures, have high aspect ratios, and/or have atomically smooth surfaces. The patterned features are made from polymer brushes grafted to a substrate. In some embodiments, the dimensions of the features may be determined by adjusting the grafting density and/or the molecular weight of the brushes. Once the brushes are patterned, the features can be shaped and reshaped with thermal or solvent treatments to achieve the desired profiles. The chemical nature of the polymer brush is thus independent of the patterning process, which allows for optimization of the polymer brush used for specific applications. Applications include masks for pattern transfer techniques such as reactive ion etching.

Abstract: The present invention provides improved and compositions methods for replicating substrate patterns including patterns containing irregular features. The methods of the invention involve depositing block copolymer materials on a patterned substrate and ordering components in the material to replicate the pattern. In some embodiments, ordering is facilitated through the use of blends of the copolymer material and/or configuring substrate patterns so that regions of the substrate pattern interact in a highly preferential manner with at least one of the components in the copolymer material. The invention also provides compositions containing a substrate pattern with irregular features replicated in a block copolymer material.