Abstract: According to various embodiments, a cover is sealed over a metasurface on a substrate to create a sealed chamber. Liquid crystal, or another tunable refractive index dielectric material, is positioned within the sealed chamber around optical structures of the metasurface before or after the cover is sealed. For example, the liquid crystal may be injected through small vias or holes to fill a sealed chamber. In some embodiments, a glass cover is shaped or patterned with photoresist to protrude into the sealed chamber to reduce the thickness of the liquid crystal used to fill the sealed chamber. A driver to control the metasurface may be, for example, integrated within the substrate, be attached to exposed bond pads of the metasurface, and/or be embodied as a control layer connected to the metasurface through the substrate by through-substrate vias (TSVs).

Abstract: According to various embodiments, a tunable optical device comprises a tunable optical metasurface on a substrate with an integrated driver circuit. In some embodiments, the tunable optical device includes a photon shield layer to prevent optical radiation from disrupting operation of the driver circuit. In some embodiments, the tunable optical device includes a diagnostic circuit to detect and disable defective optical structures of the metasurface. In some embodiments, the tunable optical device includes an integrated heater circuit that maintains a liquid crystal of the metasurface above a minimum operating temperature. In some embodiments, the tunable optical device includes an integrated lidar sequencing controller, a steering pattern subcircuit, and a photodetector circuit.

Abstract: According to various embodiments, a tunable optical metasurface includes an array of elongated resonator rails arranged parallel to one another. Liquid crystal is positioned within an optical field region between adjacent resonator rails. A controller can selectively apply a voltage differential pattern to the elongated resonator rails to adjust a phase response thereof. According to various embodiments, a cross-backplane reflector is utilized that allows for mid-array routing or edge-array routing of electrical connections between the controller and the resonator rails. The cross-backplane reflector comprises a plurality of elongated optical reflectors extending parallel to one another and perpendicular to the array of resonator rails. An optically transmissive (e.g., transparent) dielectric may electrically separate the resonator rails from the optical reflectors. A pattern of vias formed therein facilitates electrical connections between the optical reflectors and the resonator rails.

Abstract: Subwavelength conducting particles can be arranged on conducting surfaces to provide arbitrary thermal emissivity spectra. For example, a thermal emissivity spectrum can be tailored to suppress a thermal signature of an object without sacrificing radiative cooling efficiency.

Abstract: A mobile cleaning robot can include a body, a pad assembly, and a pad drive system. The pad assembly can be connected to the body and can be movable relative thereto. The pad drive system can be connected to the body and can be operable to move the pad assembly relative to the body between a stored position and a cleaning position.

Abstract: Subwavelength conducting particles can be arranged on conducting surfaces to provide arbitrary thermal emissivity spectra. For example, a thermal emissivity spectrum can be tailored to suppress a thermal signature of an object without sacrificing radiative cooling efficiency.

Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human CD200R1 receptor protein (hu-CD200R1) and are capable of decreasing, inhibiting, and/or fully-blocking immune regulatory effects mediated by hu-CD200R1. The present disclosure also provides methods of using the antibodies (and compositions thereof) to treat diseases and conditions responsive to decreasing, inhibiting and/or blocking immune regulatory function or activity mediated by CD200 binding to CD200R1.

Abstract: Machine learning systems and methods for multiscale Alzheimer's dementia recognition through spontaneous speech are provided. The system retrieves one or more audio samples and processes the one or more audio samples to extract acoustic features from audio samples. The system further processes the one or more audio samples to extract linguistic features from the audio samples. Machine learning is performed on the extracted acoustic and linguistic features, and the system indicates a likelihood of Alzheimer's disease based on output of machine learning performed on the extracted acoustic and linguistic features.

Abstract: The disclosure provides a method for fabricating a metallic optical metasurface having an array of hologram elements. The method includes forming a first copper layer protected with a conducting or dielectric barrier layer over a backplane structure by a damascene process. The first copper layer comprises a plurality of nano-gaps vertically extending from the backplane structure. The plurality of nano-gaps is filled with a dielectric material. The method also includes removing the dielectric material and a portion of the conducting or dielectric barrier layer to expose the portions in the nano-gaps of the first copper layer. The method may further include depositing a dielectric coating layer over the top portion and exposed side portions of the first copper layer to form a protected first copper layer, and filling the gaps with an electrically-tunable dielectric material that has an electrically-tunable refractive index.

Abstract: Systems and methods for machine learning of voice and other attributes are provided. The system receives input data, isolates predetermined sounds from isolated speech of a speaker of interest, summarizes the features to generate variables that describe the speaker, and generates a predictive model for detecting a desired feature of a person Also provided are systems and methods for detecting one or more attributes of a speaker based on analysis of audio samples or other types of digitally-stored information (e.g, videos, photos, etc.).

Abstract: Systems and methods for machine learning of voice and other attributes are provided. The system receives input data, isolates predetermined sounds from isolated speech of a speaker of interest, summarizes the features to generate variables that describe the speaker, and generates a predictive model for detecting a desired feature of a person Also provided are systems and methods for detecting one or more attributes of a speaker based on analysis of audio samples or other types of digitally-stored information (e.g, videos, photos, etc.).

Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36?, IL-36?, and/or IL-36?, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.

Abstract: The disclosure provides a method for fabricating a metallic optical metasurface having an array of hologram elements. The method includes forming a first copper layer protected with a conducting or dielectric barrier layer over a backplane structure by a damascene process. The first copper layer comprises a plurality of nano-gaps vertically extending from the backplane structure. The plurality of nano-gaps is filled with a dielectric material. The method also includes removing the dielectric material and a portion of the conducting or dielectric barrier layer to expose the portions in the nano-gaps of the first copper layer. The method may further include depositing a dielectric coating layer over the top portion and exposed side portions of the first copper layer to form a protected first copper layer, and filling the gaps with an electrically-tunable dielectric material that has an electrically-tunable refractive index.

Abstract: Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

Abstract: Systems, methods, and computer-readable non-transitory storage medium for communicating medical information based at least in part on an oral communication between a doctor and a patient is disclosed. In this method and system, doctor and patient's respective contexts is inferred from the oral communication. It is also preferred that diagnostic information and respective contexts of the communications can be also inferred. Then, a desired impact of a recipient to a written communication related to the oral communication is inferred. Once the desired impact is inferred, the system generates output text using an artificial intelligence system, or by accessing a database of a plurality of stock phrases, to have appropriate surface text, and subtext, and optionally appropriate tone. The output text can be selected as a function of inferred diagnostic information, the inferred doctor and recipient's respective contexts, the desired impact, and the stock phrases.

Abstract: Systems, methods, and computer-readable non-transitory storage medium in which a statistical machine translation model for formatting medical reports is trained in a learning phase using bitexts and in a tuning phase using manually transcribed dictations. Bitexts are generated from automated speech recognition dictations and corresponding formatted reports, using a series of steps including identifying matches and edits between the dictations and their corresponding reports using dynamic programming, merging matches with adjacent edits, calculating a confidence score, identifying acceptable matches, edits, and merged edits, grouping adjacent acceptable matches, edits, and merged edits, and generating a plurality of bitexts each having a predetermined maximum word count (e.g., 100 words), preferably with a predetermined overlap (e.g., two thirds) with another bitext.

Abstract: A method for assisting the transformation of a dictated, into a structured and written, report within a specialized field. The method starts with using automated speed recognition to produce a preliminary textual representation, which it then transforms into a simplified and normalized input sequence, which it copies and then transforms the copy by replacing words with tokens appropriate to the class of word as known, rare, or reducible, thereby creating a tokenized input sequence. The method then identifies and removes any preamble from the narrative text and restores punctuation, before restoring for each token within the tokenized input sequence its separable individual and original word and thus producing punctuated narrative text for processing into the written and structured report.

Abstract: A method for determining the risk of a person falling is provided. The method includes acquiring depth image data that comprises a plurality of frames that depict a person walking through a home, and extracting a foreground object from the depth image data. The method additionally includes generating a three-dimensional data object based on the foreground object, and identifying a walking sequence from the three-dimensional data object. The method further includes generating one or more gait parameters from the identified walking sequence, and comparing the one or more gait parameters against a standard clinical measure of the one or more gait parameters to determine a level of risk at which the person is of falling.

Abstract: Subwavelength conducting particles can be arranged on conducting surfaces to provide arbitrary thermal emissivity spectra. For example, a thermal emissivity spectrum can be tailored to suppress a thermal signature of an object without sacrificing radiative cooling efficiency.

Abstract: A method for determining the risk of a person falling is provided. The method includes acquiring depth image data that comprises a plurality of frames that depict a person walking through a home, and extracting a foreground object from the depth image data. The method additionally includes generating a three-dimensional data object based on the foreground object, and identifying a walking sequence from the three-dimensional data object. The method further includes generating one or more gait parameters from the identified walking sequence, and comparing the one or more gait parameters against a standard clinical measure of the one or more gait parameters to determine a level of risk at which the person is of falling.