Abstract: Various embodiments of the present invention provide methods, apparatus, systems, computing devices, computing entities, and/or the like for generating a model deficiency data object for a tensor-based graph processing machine learning model. Certain embodiments of the present invention utilize systems, methods, and computer program products that generate a model deficiency data object for a tensor-based graph processing machine learning model using holistic graph links generated by utilizing a graph representation machine learning model.

Abstract: The technology disclosed relates to hosting a virtual conference with a plurality of attendees, such that attendees in a first category have an interactive broadcast access to the virtual conference, and attendees in a second category have a view-only broadcast access to the virtual conference. The interactive broadcast access allows the attendees in the first category to share their audio and/or video with the plurality of attendees. The view-only broadcast access allows the attendees in the second category to receive audio and/or video from at least one attendee in the first category, and prevents the attendees in the second category from sharing their audio and/or video with the plurality of attendees. In response to a transition request received from a given attendee in the second category, the given attendee is transitioned from the view-only broadcast access to the interactive broadcast access.

Abstract: In some embodiments, a video (e.g. MPEG-2, H.264) transcoder channel pool is used to transcode multiple independent videos (programs) per channel substantially concurrently. A syntactically-unified combined input video stream is assembled by interleaving segments of different input video streams. The combined stream may be a container stream or elementary stream. Each segment includes one or more groups of pictures (GOP). The combined stream includes the payload video data of the input streams in unmodified form, and modified header data characterizing the combined stream as a single video stream. The combined input stream is transcoded using a single transcoder channel/input port to generate a combined output video stream. Multiple independent output video streams are assembled by de-interleaving segments of the combined output video stream according to stored interleaving break identifiers.

Abstract: In some embodiments, a video (e.g. MPEG-2, H.264) transcoder channel pool is used to transcode multiple independent videos (programs) per channel substantially concurrently. A syntactically-unified combined input video stream is assembled by interleaving segments of different input video streams. The combined stream may be a container stream or elementary stream. Each segment includes one or more groups of pictures (GOP). The combined stream includes the payload video data of the input streams in unmodified form, and modified header data characterizing the combined stream as a single video stream. The combined input stream is transcoded using a single transcoder channel/input port to generate a combined output video stream. Multiple independent output video streams are assembled by de-interleaving segments of the combined output video stream according to stored interleaving break identifiers.

Abstract: This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

Abstract: There is provided compounds of formula I, R1O(O)C—CH2—(R)Cgl-Aze-Pab-R2I wherein R1 and R2 have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.

Abstract: There is provided compounds of formula I wherein R1, Rx, Y, Ry, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided compounds of formula I wherein R1, Rx, Y, Ry, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided amino acid derivatives of formula I, wherein p, q, R1, R2, R3, R4, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided compounds of formula I, wherein R1, R2, R3, Rx, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided compounds of formula I 1

Abstract: There is provided compounds of formula I,

Abstract: There is provided compounds of formula I wherein R1, Rx, Y, Ry, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided amino acid derivatives of formula I, 1

Abstract: There is provided compounds of formulae I and IA wherein Y, R1, R2, R3, D1 and D2 have meanings given in the description which are useful as, or as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided amino acid derivatives of formula I, wherein p, q, R1, R2, R3, R4, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as hirombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided compounds of formula I wherein R1, R2, Y, R3 and R4 have meanings given in the description which are useful as, or as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided compounds of formula I, wherein R1, Rx, Y, Ry, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.

Abstract: There is provided compounds of formula I,

Abstract: There is provided amino acid derivatives of formula I, 1