Patents by Inventor Erik Regel
Erik Regel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4728356Abstract: A substituted azolylvinyl ketone or carbinol of the formula ##STR1## in which R.sup.1 represents optionally substituted cycloalkyl with 3 to 5 carbon atoms, substituted cyclohexyl or the grouping ##STR2## wherein R.sup.3 represents optionally substituted phenyl, alkenyl, alkinyl, cyano or the grouping --Z--R.sup.4,whereinR.sup.4 represents alkyl, halogenoalkyl, optionally substituted phenyl or optionally substituted phenylalkyl andZ represents O, S, SO or SO.sub.2,n represents a number from 0 to 2,R.sup.2 represents alkyl, alkenyl, alkinyl, in each case optionally substituted phenyl or phenylalkyl, or in each case optionally substituted cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, bicycloalkyl or bicycloalkenyl, but R.sup.2 does not represent optionally substituted phenyl at the same time as R.sup.1 represents optionally substituted cycloalkyl with 3 to 5 carbon atoms or substituted cyclohexyl or R.sup.Type: GrantFiled: July 12, 1985Date of Patent: March 1, 1988Assignee: Bayer AktiengesellschaftInventors: Hans-Ludwig Elbe, Wolf Reiser, Erik Regel, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes, Klaus Lurssen, Paul-Ernst Frohberger
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Patent number: 4720549Abstract: Imidazolyl-methane derivatives of the formula ##STR1## where Ar is an optionally substituted phenyl and R.sup.1 is alkyl or optionally substituted phenyl is prepared by reaction of a ketone of the formulaAr--CO--R.sup.1in which Ar and R.sup.1 have the abovementioned meanings is reacted with imidazole in the presence of formic acid.Type: GrantFiled: October 27, 1986Date of Patent: January 19, 1988Assignee: Bayer AktiengesellschaftInventors: Rudolf Zerbes, Erik Regel
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Patent number: 4699645Abstract: Compound which are azolyl-thioether derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents a CO or CH(OH) group,m is 0 or 2,R.sup.1 represents an optionally substituted phenyl radical andR.sup.2 represents an optionally substituted cycloalkyl radical or a grouping of the general formula ##STR2## wherein X and Y are identical or different and represent a hydrogen or halogen atom,Z represent an alkyl, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylthio, optionally substituted benzyloxy, optionally substituted benzylthio, alkoxy, alkylthio, halogenoalkoxy, halogenoalkylthio, alkoxycar-onyl or cyano radical, andn is 0 or 1,and the acid addition salts and metal salt complexes thereof, are novel and prepared by several processes described and find use as fungicides and as agents for regulating plant growth.Type: GrantFiled: September 5, 1985Date of Patent: October 13, 1987Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Paul-Ernst Frohberger, Klaus Lurssen
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Patent number: 4668660Abstract: The invention relates to hydroxyethylazolyl derivatives, defined herein by formula (I) and particularly to the use of said derivatives for the treatment of viral infections.Type: GrantFiled: April 10, 1984Date of Patent: May 26, 1987Assignee: Bayer AktiengesellschaftInventors: Arnold Paessens, Gert Streissle, Manfred Plempel, Karl H. B/u/ chel, Hans-Ludwig Elbe, Graham Holmwood, Udo Kraatz, Erik Regel
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Patent number: 4657920Abstract: 1,2,4-Triazol-1-yl-methyl-carbinols of the formula ##STR1## in which Ar is optionally substituted aryl, andHet is optionally substituted heteroaryl with at least 2 different hetero-atoms,or addition products thereof with plant-tolerated acids or metal salts, which possess fungicidal activity.Type: GrantFiled: March 22, 1985Date of Patent: April 14, 1987Assignee: Bayer AktiengesellschaftInventors: Jan Gajowski, Erik Regel, Karl H. Buchel, Wilhelm Brandes, Paul Reinecke
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Patent number: 4639462Abstract: Heterocyclyl-hydroxyalkyl-azolyl derivatives of the formula ##STR1## in which Az represents 1,2,4-triazol-1-yl, 1,2,4-triazol-4-yl or imidazol-1-yl,Het represents optionally substituted dioxolanyl or 1,3-dioxanyl,R represents alkyl, optionally substituted phenyl, optionally substituted phenylalkyl, optionally substituted phenoxyalky, optionally substituted phenylthioalkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, alkenyl, optionally substituted phenylalkenyl, optionally substituted cyclohexylalkenyl, furyl, naphthyloxymethyl or azolylalkyl,R' represents hydrogen, optionally substituted alkyl or alkenyl andn represents the number 0 or 1,or addition products thereof with acids or metal salts, which possess fungicidal activity.Type: GrantFiled: November 1, 1983Date of Patent: January 27, 1987Assignee: Bayer AktiengesellschaftInventors: Wolfgang Kramer, Karl H. Buchel, Graham Holmwood, Erik Regel, Paul Reinecke, Wilhelm Brandes
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Patent number: 4632932Abstract: The invention concerns the provision of compound of Formula I as defined herein as well as compositions containing compound of Formula I. Said compounds and compositions are used as antimycotic agents and the invention includes such use.Type: GrantFiled: November 8, 1983Date of Patent: December 30, 1986Assignee: Bayer AktiengesellschaftInventors: Wolfgang Kramer, Karl H. Buchel, Graham Holmwood, Erik Regel, Manfred Plempel
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Patent number: 4621095Abstract: The invention relates to bis-azolyl-substituted t-butanol derivatives defined herein under formula (I) and their use as antimycotic agents. Included in the invention are compositions containing said t-butanol derivatives and methods for using said derivatives and compositions containing them for their antimycotic activity.Type: GrantFiled: August 11, 1983Date of Patent: November 4, 1986Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Manfred Plempel
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Patent number: 4618619Abstract: A method of combating plant pathogenic fungi which comprises administering to such fungi or to a habitat thereof a plant pathogenic fungicidally effective amount of a substituted tert.-butanol derivative of the formula ##STR1## in which R.sup.1, R.sup.2 and R.sup.3 are identical or different and represent azolyl, optionally substituted phenoxy, optionally substituted phenylthio, alkylthio, alkenyl, alkinyl, optionally substituted phenylacetylenyl, alkylamino, dialkylamino, optionally substituted phenylamino, optionally substituted phenyl-N-alkyl-amino, optionally substituted cycloalkylamino, optionally substituted cycloalkyl-N-alkyl-amino, aminoethoxy, alkylaminoethoxy or dialkylaminoethyoxy,or an acid addition salt or metal salt complex thereof.Type: GrantFiled: March 14, 1984Date of Patent: October 21, 1986Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes
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Patent number: 4587239Abstract: 1-Azolyl-3-pyrazolyl-2-propanol derivatives of the general formula ##STR1## in which Az represents 1,2,4-triazol-1-yl, imidazol-1-yl or pyrazol-1-yl andR represents alkyl, alkenyl, alkinyl, optionally substituted phenyl, optionally substituted phenylalkyl, optionally substituted phenylalkenyl, optionally substituted phenylalkinyl, naphthyl or optionally substituted cycloalkyl,and acid addition salts and metal salt complexes thereof, which possess fungicidal activity. Oxirane intermediates lacking Az are also new.Type: GrantFiled: March 22, 1984Date of Patent: May 6, 1986Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Paul Reinecke, Wilhelm Brandes
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Patent number: 4585782Abstract: The invention relates to antimycotic compositions comprising (1) an antimycotic effective amount of an azole derivative having antimycotic activity, said azole derivative being in the form of particles less than 4.mu. in size, (2) an acid and/or a buffer system consisting of an organic acid and a salt thereof to provide a pH of 3 to 4 or less in aqueous solution and (3) an inert pharmaceutical carrier. Also included in the invention are methods for the short term treatment of vaginal infections utilizing the compositions of the invention.Type: GrantFiled: February 21, 1984Date of Patent: April 29, 1986Assignee: Bayer AktiengesellschaftInventors: Manfred Plempel, Manfred Bucheler, Wolfgang Gau, Erik Regel, Karl H. Buchel, Hans-Jurgen Ploschke
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Patent number: 4582717Abstract: The invention relates to a process for production of tampons containing novel formulations of antimycotic azole derivatives which provide a higher release of active compounds and make short-term therapy possible. The tampon formulations of the invention contain active antimycotic azole derivatives in impregnated form, only melting at body temperature, or dissolved form, such as, for example, in suppository bases or their combinations with emulsifiers and/or spreading agents and/or solubilisers.Type: GrantFiled: July 27, 1984Date of Patent: April 15, 1986Assignee: Bayer AktiengesellschaftInventors: Miklos von Bittera, Karl H. Buchel, Manfred Plempel, Erik Regel
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Patent number: 4559077Abstract: Compounds which are azolyl-thioether derivatives of the general formula ##STR1## in which A represents a nitrogen atom or a CH group,B represents a CO or CH(OH) group,m is 0 or 2,R.sup.1 represents an optionally substituted phenyl radical andR.sup.2 represents an optionally substituted cycloalkyl radical or a grouping of the general formula ##STR2## wherein X and Y are identical or different and represent a hydrogen or halogen atom,Z represents an alkyl, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylthio, optionally substituted benzyloxy, optionally substituted benzylthio, alkoxy, alkylthio, halogenoalkoxy, halogenoalkylthio, alkoxycar-onyl or cyano radical, andn is 0 or 1,and the acid addition salts and metal salt complexes thereof, are novel and prepared by several processes described and find use as fungicides and as agents for regulating plant growth.Type: GrantFiled: December 29, 1982Date of Patent: December 17, 1985Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Paul-Ernst Frohberger, Klaus Lurssen
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Patent number: 4549900Abstract: Substituted 1-azolyl-but-2-ones and -2-ols of the formula ##STR1## in which B is --CO-- or --CH(OH)--Az represents a 1,2,4-triazol-1-yl or -4-yl or imidazol-1-yl radical,R.sup.1 represents a hydrogen atom, an alkyl, alkenyl, alkinyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted phenoxyalkyl or optionally substituted aralkyl radical,n is 0 or 1,R.sup.2 represents a cyano radical or a grouping of the general formula --X--R.sup.3 or --CO--NR.sup.4 R.sup.5, or, if n does not represent O at the same time as R.sup.1 represents a hydrogen atom and Az represents a 1,2,4-triazolyl radical,R.sup.2 also additionally represents an optionally substituted aryl or alkoxycarbonyl radical,and whereinX represents an oxygen or sulphur atom or an SO or SO.sub.2 group,R.sup.3 represents an alkyl, halogenoalkyl, optionally substituted aryl or optionally substituted aralkyl radical,R.sup.4 represents a hydrogen atom or an alkyl or optionally substituted aryl radical, andR.sup.Type: GrantFiled: April 4, 1983Date of Patent: October 29, 1985Assignee: Bayer AktiengesellschaftInventors: Wolfgang Kramer, Karl H. Buchel, Hans-Ludwig Elbe, Udo Kraatz, Erik Regel, Paul-Ernst Frohberger, Wilhelm Brandes, Klaus Lurssen
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Patent number: 4530715Abstract: Cycloalkyl (.alpha.-triazolyl-.beta.-hydroxy)-ketones of the general formula ##STR1## in which R.sup.1 represents an optionally substituted cycloalkyl group, andR.sup.2 represents a halogenoalkyl, halogenoalkenyl or alkoxycarbonyl group,and their physiologically acceptable acid addition salts and metal salt complexes are new, are prepared as described and find use as fungicides and plant growth regulators.Type: GrantFiled: November 2, 1982Date of Patent: July 23, 1985Assignee: Bayer AktiengesellschaftInventors: Eckart Kranz, Karl H. Buchel, Udo Kraatz, Erik Regel, Wilhelm Brandes, Paul-Ernst Frohberger, Klaus Lurssen
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Patent number: 4507141Abstract: Triazolylalkyl-thioether plant growth regulators and fungicides of the formula ##STR1## in which A represents the keto group or the CH(OH) group,R.sup.1 represents alkyl, alkenyl, alkynyl, optionally substituted cycloalkyl, alkylaminoalkyl, alkoxycarbonylalkyl, optionally substituted phenyl or optionally substituted phenylalkyl,R.sup.2 represents alkyl,R.sup.3 represents alkyl or halogenoalkyl,R.sup.4 represents alkyl, halogenoalkyl, alkoxy, alkoxymethyl, alkylthio, alkylthiomethyl, optionally substituted phenyl, optionally substituted benzyl, optionally substituted phenoxy, optionally substituted phenoxymethyl, optionally substituted phenylthio, optionally substituted phenylthiomethyl, alkenyl, alkoxycarbonyl or cyano, orR.sup.3 and R.sup.4, conjointly with the carbon atom to which they are bonded, represent optionally substituted cycloalkyl andX.sup.1, X.sup.2, X.sup.3, X.sup.4 and X.sup.Type: GrantFiled: March 2, 1982Date of Patent: March 26, 1985Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Klaus Lurssen, Paul-Ernst Frohberger
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Patent number: 4499281Abstract: A substituted triazolylmethyl-oxirane of the formula ##STR1## in which R is optionally substituted alkyl, aryl or cycloalkyl is prepared by reacting a triazolyl-ketone of the formula ##STR2## with (a) dimethyloxosulphonium methylide of the formula ##STR3## or (b) trimethylsulphonium methylsulphate of the formula[(CH.sub.3).sub.3 S].sup..sym. CH.sub.3 SO.sub.4.sup..crclbar.in the presence of a diluent.The end product can then be reacted with a phenol of the formulaR"--OHto produce known fungicidally active compounds of the formula ##STR4## in which R" is optionally substituted phenyl.Type: GrantFiled: February 26, 1982Date of Patent: February 12, 1985Assignee: Bayer AktiengesellschaftInventors: Graham Holmwood, Erik Regel
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Patent number: 4480114Abstract: The invention relates to a process for the production of certain hydroxyethylazoles having antimycotic activity which comprises reacting selected phenyl-substituted oxiranes with azoles, preferably imidazoles or triazoles in the presence of an alkali metal alcoholate and a diluent. Also included in the invention are selected phenyl-substituted oxiranes as novel compounds.Type: GrantFiled: March 5, 1982Date of Patent: October 30, 1984Assignee: Bayer AktiengesellschaftInventor: Erik Regel
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Patent number: 4472395Abstract: A 2-azolylmethyl-1,3-dioxolane or -dioxane derivative of the formula ##STR1## in which Az is imidazol-1-yl or 1,2,4-triazol-1-yl,R.sup.1, R.sup.2, R.sup.3 and R.sup.5 each independently is hydrogen or alkyl, orR.sup.1 and R.sup.3 together are an optionally substituted multi-membered methylene bridge,R.sup.4 is hydrogen, optionally substituted alkyl, optionally substituted aryl or optionally substituted aralykyl,m is 0 or 1,R.sup.6 is hydrogen, halogen, cyano, alkyl, optionally substituted aryl, --X--R.sup.7, --COOR.sup.8 or --CONHR.sup.9,X is oxygen, sulphur, SO, or SO.sub.2,R.sup.7 is alkyl, halogenoalkyl, cyano, optionally substituted aralkyl or optionally substituted aryl,R.sup.8 is alkyl,R.sup.9 is alkyl or optionally substituted aryl, andn is 0 or 1, or a plant-tolerated acid addition salt or metal salt complex thereof which possesses fungicidal activity.Type: GrantFiled: January 27, 1982Date of Patent: September 18, 1984Assignee: Bayer AktiengesellschaftInventors: Wolfgang Kramer, Karl H. Buchel, Hans-Ludwig Elbe, Udo Kraatz, Wolf Reiser, Andreas Schulze, Erik Regel, Wilhelm Brandes, Paul-Ernest Frohberger
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Patent number: 4470994Abstract: The invention relates to pharmaceutical compositions containing an active antimicrobial compound of Formula (I). Also included in the invention are methods for combatting mycoses utilizing the above-identified pharmaceutical composition.Type: GrantFiled: January 27, 1982Date of Patent: September 11, 1984Assignee: Bayer AktiengesellschaftInventors: Wolfgang Kr/a/ mer, Karl H. B/u/ chel, Hans-Ludwig Elbe, Udo Kraatz, Wolf Reiser, Erik Regel, Andreas Schulze, Manfred Plempel