Patents by Inventor Erik Regel
Erik Regel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 4457938Abstract: The invention relates to stick formulations of antimycotic azole derivatives containing, in addition to the antimycotic azole derivatives, 3 to 5% by weight relative to the formulation, of benzyl alcohol, 2.5 to 10% by weight, relative to the formulation of spreading agent and one or more auxiliaries.Type: GrantFiled: February 5, 1982Date of Patent: July 3, 1984Assignee: Bayer AktiengesellschaftInventors: Miklos von Bittera, Karl H. Buchel, Manfred Plempel, Erik Regel
-
Patent number: 4452625Abstract: A plant growth-inhibiting composition comprising ##STR1## wherein the various radicals are as defined.Type: GrantFiled: January 7, 1982Date of Patent: June 5, 1984Assignee: Bayer AktiengesellschaftInventors: Klaus Lurssen, Graham Holmwood, Wolfgang Kramer, Erik Regel, Wolf Reiser, Rolf Schroder
-
Patent number: 4381306Abstract: The invention relates to hydroxypropyl-triazole compounds and methods for their preparation. Also included are compositions containing said hydroxypropyl-triazoles and methods for the use of the said active compounds and compositions, as antimycotic agents.Type: GrantFiled: November 9, 1979Date of Patent: April 26, 1983Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
-
Patent number: 4331675Abstract: A triazolyl-alkene of the formula ##STR1## in which R is an alkyl radical or an optionally substituted phenyl radical,R.sup.1 is a cycloalkyl radical, andR.sup.2 is a hydrogen atom, orR.sup.1 and R.sup.2 together, in the o-position relative to each other, are an optionally substituted polymethylene bridge, or, together with the phenyl ring, are naphthyl,R.sup.3 is a halogen atom or an alkyl, alkoxy or halogenoalkyl radical,n is 0, 1, 2 or 3, andX is a keto radical or a --CH(OH)-radical,or an acid addition salt or metal salt complex thereof, which possesses fungicidal activity.Type: GrantFiled: July 2, 1980Date of Patent: May 25, 1982Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Paul-Ernst Frohberger, Wilhelm Brandes, Volker Paul
-
Patent number: 4301166Abstract: The invention relates to hydroxyethyl-azole compounds and methods for their preparation. Also included in the invention are compositions containing said hydroxyethyl-azole compounds and methods for the use of said compounds and compositions as antimycotic agents.Type: GrantFiled: November 9, 1979Date of Patent: November 17, 1981Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
-
Patent number: 4251540Abstract: .alpha.-(4-Biphenylyl)-benzyl-azolium salts of the formula ##STR1## in which A is CH or N,R.sup.1 and R.sup.2 each independently is hydrogen, alkyl or optionally substituted phenyl,R.sup.3 is hydrogen, alkyl or optionally substituted phenyl, phenylalkyl, phenylcarbonyl or phenylcarbonylalkyl,m is 0, 1, 2, 3, 4 or 5,X each independently is halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro or cyano,n is 0, 1, 2, 3, 4 or 5,Y each independently is halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro, cyano or phenyl which is optionally substituted by halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro or cyano, andZ is the anion of an inorganic or organic acid,are used to combat fungi.Type: GrantFiled: September 6, 1979Date of Patent: February 17, 1981Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Peter Kraus, Wilhelm Brandes
-
Patent number: 4246274Abstract: The invention includes as a series of 2-(substituted-phenyl)-1-aryl-3-(imidazol-1-yl)-propan-2-ols useful as antimicrobial agents. Also included in the invention are methods for the manufacture of the above-identified imidazol-1-yl-propan-2-ols, compositions containing said compounds and the use of said compounds and compositions for antimicrobial use.Type: GrantFiled: April 17, 1979Date of Patent: January 20, 1981Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
-
Patent number: 4243670Abstract: The present invention relates to novel .alpha.-(4-biphenylyl)-benzyl-azolium salts of the general formula ##STR1## in which A represents the CH group or a N atomR.sup.1 and R.sup.2 are identical or different and each represents hydrogen, alkyl or optionally substituted phenyl,R.sup.3 represents hydrogen, alkyl, or an optionally substituted phenyl, phenylalkyl, phenylcarbonyl or phenylcarbonylalkyl group,X represents halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro or cyano,Y represents X or optionally substituted phenyl,m and n each represents 0 or an integer from1 to 5 andZ represents the anion of an inorganic or organic acid.The invention also includes processes for the preparation of the compounds and, in addition includes compositions containing the compounds and methods for their use. The compounds of the invention exhibit antimicrobial activity and sporicidal activity.Type: GrantFiled: February 23, 1979Date of Patent: January 6, 1981Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Manfred Plempel
-
Patent number: 4239765Abstract: The invention relates to fluorenylazolylmethylcarbinols and methods for their preparation. Also included are compositions containing said fluorenylazolylmethyl-carbinols and methods for the use of said carbinols and compositions containing them as antimycotic agents.Type: GrantFiled: November 9, 1979Date of Patent: December 16, 1980Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl Buchel, Ingo Haller, Manfred Plempel
-
Patent number: 4238498Abstract: The invention provides a series of substituted diphenyl-imidazolyl-methanes useful as antimycotic agents. Also included in the invention are pharmaceutical compositions containing said diphenyl-imidazolyl-methanes and methods for the use of said compounds and compositions. The invention additionally includes methods for the manufacture of the diphenyl-imidazolyl-methanes.Type: GrantFiled: February 1, 1979Date of Patent: December 9, 1980Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl H. Buchel, Wilfried Draber, Manfred Plempel, Ingo Haller
-
Patent number: 4174398Abstract: 1-Alkyl-1-(1,3,4-thiadiazol-2-yl)-3-phenyl-ureas of the formula ##STR1## in which R.sup.1 is alkyl,R.sup.2 is phenyl or substituted phenyl, andX is hydrogen or halogen,which possess fungicidal properties.Type: GrantFiled: March 2, 1978Date of Patent: November 13, 1979Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Paul-Ernst Frohberger, Volker Paul
-
Patent number: 4141981Abstract: Antimycotic compositions in topical or vaginal administration form are prepared wherein the active agent is imidazol-1-yl-(4-phenoxyphenyl)-(pyridin-2-yl)phenylmethane in combination with a pharmaceutically acceptable carrier suitable for topical application to the skin of a human or suitable for vaginal administration to humans. Such compositions are useful for treating mycoses in humans.Type: GrantFiled: July 5, 1977Date of Patent: February 27, 1979Assignee: Bayer AktiengesellschaftInventors: Wilfried Draber, Manfred Plempel, Karl H. Buchel, Erik Regel
-
Patent number: 4118487Abstract: Azol-1-ylmethanes substituted on the methane carbon atom by (a) phenyl or lower alkyl and (b) by a biphenyl-4-yl, 4-phenoxyphenyl, 4-phenylthiophenyl, 4-phenylsulfinylphenyl or 4-phenylsulfonylphenyl group are antimycotic and antibacterial agents. The compounds, of which (biphenyl-4-yl)phenyl-imidazol-1-ylmethane is a typical example, are prepared from the correspondingly substituted carbinol through treatment with thionyl-bis-azole or from the correspondingly substituted methyl halide with the azole or a derivative thereof.Type: GrantFiled: December 5, 1975Date of Patent: October 3, 1978Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Wilfried Draber, Karl Heinz Buchel, Manfred Plempel
-
Patent number: 4117142Abstract: Imidazoles of the formula ##STR1## and pharmaceutically acceptable nontoxic salts thereof, wherein X is methyl or chloro,Y is methyl or chloro, or, when Z is methyl or chloro, Y is hydrogen, andZ is methyl or chloro, or, when Y is methyl or chloro, Z is hydrogen,Are useful as antimycotics for the treatment of mycotic infections in humans and animals. The imidazoles may be produced by reacting the corresponding triphenylmethylcarbinol with a brominating or chlorinating agent and thereafter reacting the resultant triphenylmethyl halide, either with or without isolation, with imidazole in the presence or absence of an acid-binding agent, or they may be prepared by reacting a triphenylmethyl halide with imidazole, either in the presence or absence of an acid-binding agent.Type: GrantFiled: September 27, 1976Date of Patent: September 26, 1978Assignee: Bayer AktiengesellschaftInventors: Karl Heinz Buchel, Erik Regel, Manfred Plempel
-
Patent number: 4073636Abstract: New azolylamidines of the formula ##STR1## WHEREIN N IS AN INTEGER FROM 0 TO 5,R.sup.1 is halogen, alkyl, alkoxy, alkylthio, haloalkoxy, haloalkylthio, halophenoxy or haloalkyl;R.sup.2 and R.sup.3, independently of one another, are each hydrogen, alkyl, alkoxyalkyl, cycloalkyl, alkoxy or alkoxycarbonylalkyl, of, preferably not more than 7 carbon atoms; or taken together, represent a lower alkylene bridge which can be interrupted by one or more hetero-atoms; andAz represents an azolyl radical selected from imidazol-1-yl, pyrrol-1-yl, pyrazol-1-yl,1,2,4-triazol-1-yl, 1,2,4-triazol-4-yl or 1,2,3-triazol-1-yl,And their salts are outstandingly effective herbicides showing particularly selective action.Type: GrantFiled: August 26, 1975Date of Patent: February 14, 1978Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Ludwig Eue, Robert R. Schmidt
-
Patent number: 4062959Abstract: N-methyl-imidazole derivatives of the formula: ##STR1## or a pharmaceutically acceptable non-toxic salt thereof, wherein X is an unsubstituted or substituted 6-membered heteroaromatic moiety having two nitro heteroatoms,Y is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety or an unsubstituted or substituted aryl moiety, andZ is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety, an unsubstituted or substituted aryl moiety, an unsubstituted or substituted pyridyl moiety or an alkoxycarbonyl moiety,Are useful as antimycotic agents.Type: GrantFiled: February 28, 1975Date of Patent: December 13, 1977Assignee: Bayer AktiengesellschaftInventors: Wilfried Draber, Karl Heinz Buchel, Erik Regel, Manfred Plempel
-
Patent number: 4052409Abstract: Imidazoles of the formula ##STR1## and pharmaceutically acceptable nontoxic salts thereof, wherein X is methyl or chloro,Y is methyl or chloro, or, when Z is methyl or chloro, Y is hydrogen, andZ is methyl or chloro, or, when Y is methyl or chloro, Z is hydrogen,Are useful as antimycotics for the treatment of mycotic infections in humans and animals. The imidazoles may be produced by reacting the corresponding triphenylmethylcarbinol with a brominating or chlorinating agent and thereafter reacting the resultant triphenylmethyl halide, either with or without isolation, with imidazole in the presence or absence of an acid-binding agent, or they may be prepared by reacting a triphenylmethyl halide with imidazole, either in the presence or absence of an acid-binding agent.Type: GrantFiled: March 8, 1973Date of Patent: October 4, 1977Assignee: Bayer AktiengesellschaftInventors: Karl Heinz Buchel, Erik Regel, Manfred Plempel
-
Patent number: 3993469Abstract: New azolylamidines of the formula ##SPC1##Whereinn is an integer from 0 to 5,R.sup.1 is halogen, alkyl, alkoxy, alkylthio, haloalkoxy, haloalkylthio, halophenoxy or haloalkyl;R.sup.2 and R.sup.3, independently of one another, are each hydrogen, alkyl, alkoxyalkyl, cycloalkyl, alkoxy or alkoxycarbonylalkyl, of, preferably not more than 7 carbon atoms; or taken together, represent a lower alkylene bridge which can be interrupted by one or more hetero-atoms; andAz represents an azolyl radical selected from imidazol-1-yl, pyrrol-1-yl, pyrazol-1-yl, 1,2,4-triazol-1-yl, 1,2,4-triazol-4-yl or 1,2,3-triazol-1-yl,And their salts are outstandingly effective herbicides showing particularly selective action.Type: GrantFiled: April 8, 1974Date of Patent: November 23, 1976Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Ludwig Eue, Robert R. Schmidt
-
Patent number: 3985766Abstract: Bis-imidazolyl-bisphenylmethane derivatives and pharmaceutically acceptable non-toxic salts thereof are useful as antimycotics especially against dermatomycosis caused by Trichophyton and Microsporium species and also against yeast infections of the skin and internal organs.Type: GrantFiled: October 31, 1969Date of Patent: October 12, 1976Assignee: Bayer AktiengesellschaftInventors: Erik Regel, Karl Heinz Buchel, Manfred Plempel
-
Patent number: 3980780Abstract: N-methyl-imidazole derivatives of the formula: ##EQU1## or a pharmaceutically acceptable non-toxic salt thereof, wherein X is an unsubstituted or substituted 6-membered heteroaromatic moiety having two nitro heteroatoms,Y is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety or an unsubstituted or substituted aryl moiety, andZ is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety, an unsubstituted or substituted aryl moiety, an unsubstituted or substituted pyridyl moiety or an alkoxycarbonyl moiety,Are useful as antimycotic agents.Type: GrantFiled: February 28, 1975Date of Patent: September 14, 1976Assignee: Bayer AktiengesellschaftInventors: Wilfried Draber, Karl Heinz Buchel, Erik Regel, Manfred Plempel