Patents by Inventor Erik Regel

Erik Regel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4457938
    Abstract: The invention relates to stick formulations of antimycotic azole derivatives containing, in addition to the antimycotic azole derivatives, 3 to 5% by weight relative to the formulation, of benzyl alcohol, 2.5 to 10% by weight, relative to the formulation of spreading agent and one or more auxiliaries.
    Type: Grant
    Filed: February 5, 1982
    Date of Patent: July 3, 1984
    Assignee: Bayer Aktiengesellschaft
    Inventors: Miklos von Bittera, Karl H. Buchel, Manfred Plempel, Erik Regel
  • Patent number: 4452625
    Abstract: A plant growth-inhibiting composition comprising ##STR1## wherein the various radicals are as defined.
    Type: Grant
    Filed: January 7, 1982
    Date of Patent: June 5, 1984
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Lurssen, Graham Holmwood, Wolfgang Kramer, Erik Regel, Wolf Reiser, Rolf Schroder
  • Patent number: 4381306
    Abstract: The invention relates to hydroxypropyl-triazole compounds and methods for their preparation. Also included are compositions containing said hydroxypropyl-triazoles and methods for the use of the said active compounds and compositions, as antimycotic agents.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: April 26, 1983
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
  • Patent number: 4331675
    Abstract: A triazolyl-alkene of the formula ##STR1## in which R is an alkyl radical or an optionally substituted phenyl radical,R.sup.1 is a cycloalkyl radical, andR.sup.2 is a hydrogen atom, orR.sup.1 and R.sup.2 together, in the o-position relative to each other, are an optionally substituted polymethylene bridge, or, together with the phenyl ring, are naphthyl,R.sup.3 is a halogen atom or an alkyl, alkoxy or halogenoalkyl radical,n is 0, 1, 2 or 3, andX is a keto radical or a --CH(OH)-radical,or an acid addition salt or metal salt complex thereof, which possesses fungicidal activity.
    Type: Grant
    Filed: July 2, 1980
    Date of Patent: May 25, 1982
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Paul-Ernst Frohberger, Wilhelm Brandes, Volker Paul
  • Patent number: 4301166
    Abstract: The invention relates to hydroxyethyl-azole compounds and methods for their preparation. Also included in the invention are compositions containing said hydroxyethyl-azole compounds and methods for the use of said compounds and compositions as antimycotic agents.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: November 17, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
  • Patent number: 4251540
    Abstract: .alpha.-(4-Biphenylyl)-benzyl-azolium salts of the formula ##STR1## in which A is CH or N,R.sup.1 and R.sup.2 each independently is hydrogen, alkyl or optionally substituted phenyl,R.sup.3 is hydrogen, alkyl or optionally substituted phenyl, phenylalkyl, phenylcarbonyl or phenylcarbonylalkyl,m is 0, 1, 2, 3, 4 or 5,X each independently is halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro or cyano,n is 0, 1, 2, 3, 4 or 5,Y each independently is halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro, cyano or phenyl which is optionally substituted by halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro or cyano, andZ is the anion of an inorganic or organic acid,are used to combat fungi.
    Type: Grant
    Filed: September 6, 1979
    Date of Patent: February 17, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Peter Kraus, Wilhelm Brandes
  • Patent number: 4246274
    Abstract: The invention includes as a series of 2-(substituted-phenyl)-1-aryl-3-(imidazol-1-yl)-propan-2-ols useful as antimicrobial agents. Also included in the invention are methods for the manufacture of the above-identified imidazol-1-yl-propan-2-ols, compositions containing said compounds and the use of said compounds and compositions for antimicrobial use.
    Type: Grant
    Filed: April 17, 1979
    Date of Patent: January 20, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Karl H. Buchel, Ingo Haller, Manfred Plempel
  • Patent number: 4243670
    Abstract: The present invention relates to novel .alpha.-(4-biphenylyl)-benzyl-azolium salts of the general formula ##STR1## in which A represents the CH group or a N atomR.sup.1 and R.sup.2 are identical or different and each represents hydrogen, alkyl or optionally substituted phenyl,R.sup.3 represents hydrogen, alkyl, or an optionally substituted phenyl, phenylalkyl, phenylcarbonyl or phenylcarbonylalkyl group,X represents halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, nitro or cyano,Y represents X or optionally substituted phenyl,m and n each represents 0 or an integer from1 to 5 andZ represents the anion of an inorganic or organic acid.The invention also includes processes for the preparation of the compounds and, in addition includes compositions containing the compounds and methods for their use. The compounds of the invention exhibit antimicrobial activity and sporicidal activity.
    Type: Grant
    Filed: February 23, 1979
    Date of Patent: January 6, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Wilfried Draber, Karl H. Buchel, Manfred Plempel
  • Patent number: 4239765
    Abstract: The invention relates to fluorenylazolylmethylcarbinols and methods for their preparation. Also included are compositions containing said fluorenylazolylmethyl-carbinols and methods for the use of said carbinols and compositions containing them as antimycotic agents.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: December 16, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Karl Buchel, Ingo Haller, Manfred Plempel
  • Patent number: 4238498
    Abstract: The invention provides a series of substituted diphenyl-imidazolyl-methanes useful as antimycotic agents. Also included in the invention are pharmaceutical compositions containing said diphenyl-imidazolyl-methanes and methods for the use of said compounds and compositions. The invention additionally includes methods for the manufacture of the diphenyl-imidazolyl-methanes.
    Type: Grant
    Filed: February 1, 1979
    Date of Patent: December 9, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Karl H. Buchel, Wilfried Draber, Manfred Plempel, Ingo Haller
  • Patent number: 4174398
    Abstract: 1-Alkyl-1-(1,3,4-thiadiazol-2-yl)-3-phenyl-ureas of the formula ##STR1## in which R.sup.1 is alkyl,R.sup.2 is phenyl or substituted phenyl, andX is hydrogen or halogen,which possess fungicidal properties.
    Type: Grant
    Filed: March 2, 1978
    Date of Patent: November 13, 1979
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Paul-Ernst Frohberger, Volker Paul
  • Patent number: 4141981
    Abstract: Antimycotic compositions in topical or vaginal administration form are prepared wherein the active agent is imidazol-1-yl-(4-phenoxyphenyl)-(pyridin-2-yl)phenylmethane in combination with a pharmaceutically acceptable carrier suitable for topical application to the skin of a human or suitable for vaginal administration to humans. Such compositions are useful for treating mycoses in humans.
    Type: Grant
    Filed: July 5, 1977
    Date of Patent: February 27, 1979
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilfried Draber, Manfred Plempel, Karl H. Buchel, Erik Regel
  • Patent number: 4118487
    Abstract: Azol-1-ylmethanes substituted on the methane carbon atom by (a) phenyl or lower alkyl and (b) by a biphenyl-4-yl, 4-phenoxyphenyl, 4-phenylthiophenyl, 4-phenylsulfinylphenyl or 4-phenylsulfonylphenyl group are antimycotic and antibacterial agents. The compounds, of which (biphenyl-4-yl)phenyl-imidazol-1-ylmethane is a typical example, are prepared from the correspondingly substituted carbinol through treatment with thionyl-bis-azole or from the correspondingly substituted methyl halide with the azole or a derivative thereof.
    Type: Grant
    Filed: December 5, 1975
    Date of Patent: October 3, 1978
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Wilfried Draber, Karl Heinz Buchel, Manfred Plempel
  • Patent number: 4117142
    Abstract: Imidazoles of the formula ##STR1## and pharmaceutically acceptable nontoxic salts thereof, wherein X is methyl or chloro,Y is methyl or chloro, or, when Z is methyl or chloro, Y is hydrogen, andZ is methyl or chloro, or, when Y is methyl or chloro, Z is hydrogen,Are useful as antimycotics for the treatment of mycotic infections in humans and animals. The imidazoles may be produced by reacting the corresponding triphenylmethylcarbinol with a brominating or chlorinating agent and thereafter reacting the resultant triphenylmethyl halide, either with or without isolation, with imidazole in the presence or absence of an acid-binding agent, or they may be prepared by reacting a triphenylmethyl halide with imidazole, either in the presence or absence of an acid-binding agent.
    Type: Grant
    Filed: September 27, 1976
    Date of Patent: September 26, 1978
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl Heinz Buchel, Erik Regel, Manfred Plempel
  • Patent number: 4073636
    Abstract: New azolylamidines of the formula ##STR1## WHEREIN N IS AN INTEGER FROM 0 TO 5,R.sup.1 is halogen, alkyl, alkoxy, alkylthio, haloalkoxy, haloalkylthio, halophenoxy or haloalkyl;R.sup.2 and R.sup.3, independently of one another, are each hydrogen, alkyl, alkoxyalkyl, cycloalkyl, alkoxy or alkoxycarbonylalkyl, of, preferably not more than 7 carbon atoms; or taken together, represent a lower alkylene bridge which can be interrupted by one or more hetero-atoms; andAz represents an azolyl radical selected from imidazol-1-yl, pyrrol-1-yl, pyrazol-1-yl,1,2,4-triazol-1-yl, 1,2,4-triazol-4-yl or 1,2,3-triazol-1-yl,And their salts are outstandingly effective herbicides showing particularly selective action.
    Type: Grant
    Filed: August 26, 1975
    Date of Patent: February 14, 1978
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Ludwig Eue, Robert R. Schmidt
  • Patent number: 4062959
    Abstract: N-methyl-imidazole derivatives of the formula: ##STR1## or a pharmaceutically acceptable non-toxic salt thereof, wherein X is an unsubstituted or substituted 6-membered heteroaromatic moiety having two nitro heteroatoms,Y is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety or an unsubstituted or substituted aryl moiety, andZ is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety, an unsubstituted or substituted aryl moiety, an unsubstituted or substituted pyridyl moiety or an alkoxycarbonyl moiety,Are useful as antimycotic agents.
    Type: Grant
    Filed: February 28, 1975
    Date of Patent: December 13, 1977
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilfried Draber, Karl Heinz Buchel, Erik Regel, Manfred Plempel
  • Patent number: 4052409
    Abstract: Imidazoles of the formula ##STR1## and pharmaceutically acceptable nontoxic salts thereof, wherein X is methyl or chloro,Y is methyl or chloro, or, when Z is methyl or chloro, Y is hydrogen, andZ is methyl or chloro, or, when Y is methyl or chloro, Z is hydrogen,Are useful as antimycotics for the treatment of mycotic infections in humans and animals. The imidazoles may be produced by reacting the corresponding triphenylmethylcarbinol with a brominating or chlorinating agent and thereafter reacting the resultant triphenylmethyl halide, either with or without isolation, with imidazole in the presence or absence of an acid-binding agent, or they may be prepared by reacting a triphenylmethyl halide with imidazole, either in the presence or absence of an acid-binding agent.
    Type: Grant
    Filed: March 8, 1973
    Date of Patent: October 4, 1977
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl Heinz Buchel, Erik Regel, Manfred Plempel
  • Patent number: 3993469
    Abstract: New azolylamidines of the formula ##SPC1##Whereinn is an integer from 0 to 5,R.sup.1 is halogen, alkyl, alkoxy, alkylthio, haloalkoxy, haloalkylthio, halophenoxy or haloalkyl;R.sup.2 and R.sup.3, independently of one another, are each hydrogen, alkyl, alkoxyalkyl, cycloalkyl, alkoxy or alkoxycarbonylalkyl, of, preferably not more than 7 carbon atoms; or taken together, represent a lower alkylene bridge which can be interrupted by one or more hetero-atoms; andAz represents an azolyl radical selected from imidazol-1-yl, pyrrol-1-yl, pyrazol-1-yl, 1,2,4-triazol-1-yl, 1,2,4-triazol-4-yl or 1,2,3-triazol-1-yl,And their salts are outstandingly effective herbicides showing particularly selective action.
    Type: Grant
    Filed: April 8, 1974
    Date of Patent: November 23, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Ludwig Eue, Robert R. Schmidt
  • Patent number: 3985766
    Abstract: Bis-imidazolyl-bisphenylmethane derivatives and pharmaceutically acceptable non-toxic salts thereof are useful as antimycotics especially against dermatomycosis caused by Trichophyton and Microsporium species and also against yeast infections of the skin and internal organs.
    Type: Grant
    Filed: October 31, 1969
    Date of Patent: October 12, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Erik Regel, Karl Heinz Buchel, Manfred Plempel
  • Patent number: 3980780
    Abstract: N-methyl-imidazole derivatives of the formula: ##EQU1## or a pharmaceutically acceptable non-toxic salt thereof, wherein X is an unsubstituted or substituted 6-membered heteroaromatic moiety having two nitro heteroatoms,Y is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety or an unsubstituted or substituted aryl moiety, andZ is an unsubstituted or substituted aliphatic moiety, an unsubstituted or substituted cycloaliphatic moiety, an unsubstituted or substituted aralkyl moiety, an unsubstituted or substituted aryl moiety, an unsubstituted or substituted pyridyl moiety or an alkoxycarbonyl moiety,Are useful as antimycotic agents.
    Type: Grant
    Filed: February 28, 1975
    Date of Patent: September 14, 1976
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilfried Draber, Karl Heinz Buchel, Erik Regel, Manfred Plempel