Abstract: A biocompatible hydrogel comprises a specified content of polyacrylamide and pyrogen-free water. Also disclosed is a method of making the hydrogel and an injectable or implantable endoprosthesis. The hydrogel may also be used to treat a cosmetic or functional defect. Hydrogels specified according to their polyacrylamide content may be used for medical indications, such as an implantable or injectable endoprostheses for mammoplastic reconstruction, implantable or injectable endoprostheses for treating (reflux) oesophagitis, and for body contouring of various body parts.

Abstract: A system for remotely logging into a personal computer includes a controller coupled to the personal computer and a remote control device. The controller memorizes a login password for the personal computer. The remote control device transmits a login signal to which the controller responds by sending the memorized login password to the personal computer. When the personal computer is located in an automobile that includes apparatus for adjusting at least one component of the automobile to provide a plurality of arrangements of the at least one component, the controller controls the adjusting apparatus and memorizes at least a first component arrangement associated with the personal computer; and the controller responds to a first component arrangement signal received from a location remote from the controller by controlling the adjusting apparatus to provide the memorized first component arrangement.

Abstract: Management in a database of inventions, ideas, and rights related to inventions including publication of ideas for inventions accumulated in a computer database. A computerized method includes establishing a contractual obligation by a prospective contributor of an idea contribution for the database to transfer property rights of a prospectively patentable invention. The contributor is enabled to view at least some other idea contributions accumulated in the database. The idea contribution is received for the database from the contributor. Ownership of a contractual benefit is provided to the contributor, wherein the contractual benefit is transferred from the owner of the contractual benefit to a new owner of the contractual benefit. The idea contribution from the database is published. Some of the property rights are transferred to a customer to allow the customer to file a patent application and/or remuneration is distributed to the new owner in exchange for the contractual benefit.

Abstract: The present invention relates to a set of coupling parts, such as parts for coupling an ostomy bag to a base plate, said base plate being adhered around a stoma. The set of coupling parts provides a set of coupling parts wherein a connection part may be interposed between a first coupling part and a second coupling part and where the coupling parts may be connected and disconnected from each other by the same movement of the connection part.

Abstract: The present invention relates to a process for forming stabilized metal salt particles.

Abstract: A method of managing ideas includes the following steps: (a) maintaining a computer database for accumulating ideas for prospectively patentable inventions; (b) systematically establishing contractual obligations by contributors of said ideas to said database to transfer property rights to inventions respectively derived at least in part from said contributed ideas to a proprietor of said database or to a party in concert with said proprietor; and (c) prior to filing any patent applications for inventions respectively derived at least in part from said accumulated ideas, systematically publishing said accumulated ideas.

Abstract: A method of managing ideas includes the following steps: (a) maintaining a computer database for accumulating ideas for prospectively patentable inventions; (b) systematically establishing contractual obligations by contributors of said ideas to said database to transfer property rights to inventions respectively derived at least in part from said contributed ideas to a proprietor of said database or to a party in concert with said proprietor; and (c) prior to filing any patent applications for inventions respectively derived at least in part from said accumulated ideas, systematically publishing said accumulated ideas.

Abstract: A system for remotely logging into a personal computer includes a controller coupled to the personal computer and a remote control device. The controller memorizes a login password for the personal computer. The remote control device transmits a login signal to which the controller responds by causing the personal computer to be turned on and by sending the memorized login password to the personal computer. When the personal computer is located in an automobile that includes apparatus for adjusting at least one component of the automobile to provide a plurality of arrangements of the at least one component, the controller controls the adjusting apparatus and memorizes at least a first component arrangement associated with the personal computer; and the controller responds to a first component arrangement signal received from a location remote from the controller by controlling the adjusting apparatus to provide the memorized first component arrangement.

Abstract: A computer-implemented method for deriving prospectively patentable inventions including accumulating a plurality of the idea contributions for prospectively patentable inventions in a database, where at least one of the idea contributions comprises at least one parent idea contribution, at least one idea contribution from which the parent idea contribution was previously derived and at least one child idea contribution. The child idea contribution was derived from the parent idea contribution by editing of the parent idea contribution, and the child idea is a prospective improvement of the parent idea. The child idea contribution is displayed so as to include indicia of differences between the child idea contribution and the parent idea contribution, and so as to not include indicia of differences between the parent idea contribution and the idea contribution from which the parent idea contribution was previously derived.

Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000, preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.

Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.

Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000 , preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.

Abstract: A control system causes arrangements of automobile components, such as the driver's seat, the steering wheel and one or more mirrors, to be adjusted to a plurality of different memorized preferred component arrangements in response to unique component-arrangement signals respectively received from a plurality of remote control devices. The unique component-arrangement signals are transmitted by the remote control devices together with an unlock-request signal that causes a keyless-entry system to unlock one or more doors of the automobile. The control system responds to a lock-request signal that causes the keyless-entry system to lock the doors by causing the driver's seat to be adjusted to a locked position that cannot be utilized for driving the automobile. A distance measuring system separately measures the distance over which the automobile is driven while respectively in at least some of the plurality of preferred component arrangements.

Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000, preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.

Abstract: The present invention provides methods for analyzing proteomes, as cells or lysates. The analysis is based on the use of probes that have specificity to the active form of proteins, particularly enzymes and receptors. The probes can be identified in different ways. In accordance with the present invention, a method is provided for generating and screening compound libraries that are used for the identification of lead molecules, and for the parallel identification of their biological targets. By appending specific functionalities and/or groups to one or more binding moieties, the reactive functionalities gain binding affinity and specificity for particular proteins and classes of proteins. Such libraries of candidate compounds, referred to herein as activity-based probes, or ABPs, are used to screen for one or more desired biological activities or target proteins.

Abstract: The present invention provides methods for analyzing proteomes, as cells or lysates. The analysis is based on the use of probes that have specificity to the active form of proteins, particularly enzymes and receptors. The probes can be identified in different ways. In accordance with the present invention, a method is provided for generating and screening compound libraries that are used for the identification of lead molecules, and for the parallel identification of their biological targets. By appending specific functionalities and/or groups to one or more binding moieties, the reactive functionalities gain binding affinity and specificity for particular proteins and classes of proteins. Such libraries of candidate compounds, referred to herein as activity-based probes, or ABPs, are used to screen for one or more desired biological activities or target proteins.

Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.

Abstract: The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.

Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000, preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.

Abstract: The present invention relates to compositions comprising poly-HEMA having a peak molecular weight between about 25,000 and about 100,000, preferably between 25,000 and 80,000 and a polydispersity of less than about 2 to less than about 3.8 respectively and covalently bonded thereon, at least one cross-linkable functional group. The present invention further relates to low polydispersity poly-HEMA suitable for making the crosslinkable prepolymers, processes for functionalizing and purifying said poly-HEMA to form said crosslinkable prepolymers, viscous solutions made from said crosslinkable prepolymers, hydrogels made from said viscous solutions and articles made from said crosslinkable polymers, hydrogels and viscous solutions.