Patents by Inventor Ernest G. Schutt

Ernest G. Schutt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240108799
    Abstract: A system for flushing a lumen of a medical device to remove air, comprising: a first fluid delivery device adapted to provide a pulsatile flow of a flushing gas from a pressurised source of the flushing gas; a second fluid delivery device adapted to provide a pulsatile flow of a flushing liquid from a source of the flushing liquid; and, at least one fluid coupling for connecting the first fluid delivery device and the second fluid delivery device to the lumen of the medical device.
    Type: Application
    Filed: December 15, 2021
    Publication date: April 4, 2024
    Applicant: Mokita Medical GmbH
    Inventors: Richard Gerard Vecchiotti, Ernest G. Schutt, Joshua Bough, Rosemary Burnell, Tilo Kölbel, Andrew Macleod
  • Publication number: 20230414525
    Abstract: The present invention provides novel compositions and methods for targeted delivery of therapeutics. In particular, the invention provides compositions comprising a plurality of carriers, such as microbubbles, wherein at least one active agent is associated or co-administered with the plurality of carriers for delivery to a target site, e.g., an organ, a tissue, or a tumor site, in a subject. The present invention also provides methods for treating a disease or condition, methods of targeted delivery of an active agent, e.g., to a target site, in a subject, using the carriers based compositions of the invention. The present invention further provides apparatus, devices and methods for preparing the compositions of the present invention.
    Type: Application
    Filed: August 29, 2023
    Publication date: December 28, 2023
    Applicant: VESSELON, INC.
    Inventors: Rhodemann Li, Clayton Larsen, Ernest G. Schutt, Llew Keltner
  • Publication number: 20230058977
    Abstract: The present invention provides novel compositions and methods for targeted delivery of therapeutics. In particular, the invention provides compositions comprising a plurality of carriers, such as microbubbles, wherein at least one active agent is associated or co-administered with the plurality of carriers for delivery to a target site, e.g., an organ, a tissue, or a tumor site, in a subject. The present invention also provides methods for treating a disease or condition, methods of targeted delivery of an active agent, e.g., to a target site, in a subject, using the carriers based compositions of the invention. The present invention further provides apparatus, devices and methods for preparing the compositions of the present invention.
    Type: Application
    Filed: May 12, 2022
    Publication date: February 23, 2023
    Applicant: VESSELON, INC.
    Inventors: Rhodemann Li, Clayton Larsen, Ernest G. Schutt, Llew Keltner
  • Publication number: 20220296336
    Abstract: The present invention relates to a system for flushing a medical device, comprising a multi-port valve for controlling the delivery of flushing fluids, the multi-port valve connected to a source of pressurised flushing gas; a fluid outlet for coupling flushing fluids to the medical device; and, a gas-driven pump connected to the fluid outlet, wherein, in a first configuration, the multi-port valve couples a flow of gas from the source of pressurised flushing gas to the fluid outlet, and wherein, in a second configuration, the multi-port valve couples a flow of gas from the source of pressurised flushing gas to the gas-driven pump to drive the gas-driven pump thereby to provide a flow of flushing liquid to the fluid outlet.
    Type: Application
    Filed: August 26, 2020
    Publication date: September 22, 2022
    Applicant: MOKITA MEDICAL GMBH
    Inventors: RICHARD GERARD VECCHIOTTI, TILO KÖLBEL, ERNEST G SCHUTT
  • Publication number: 20210299047
    Abstract: Embodiments of the present disclosure are related to multivesicular liposome formulations encapsulating zinc meloxicam complex microparticles. Methods of making the zinc meloxicam complex microparticles and administering the zinc meloxicam complex microparticles encapsulated in multivesicular liposome formulations and their use as medicaments are also provided.
    Type: Application
    Filed: June 10, 2021
    Publication date: September 30, 2021
    Inventors: Louie Daniel Garcia, Stephanie Kurz, Soroush Ardekani, Kathleen Dunne Albright Los, Katherine Stone, Ernest G. Schutt, Vladimir Kharitonov
  • Patent number: 11040011
    Abstract: Embodiments of the present disclosure are related to multivesicular liposome formulations encapsulating zinc meloxicam complex microparticles. Methods of making the zinc meloxicam complex microparticles and administering the zinc meloxicam complex microparticles encapsulated in multivesicular liposome formulations and their use as medicaments are also provided.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: June 22, 2021
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Louie Daniel Garcia, Stephanie Kurz, Soroush Ardekani, Kathleen Dunne Albright Los, Katherine Stone, Ernest G. Schutt, Vladimir Kharitonov
  • Publication number: 20200397699
    Abstract: Embodiments of the present disclosure are related to multivesicular liposome formulations encapsulating zinc meloxicam complex microparticles. Methods of making the zinc meloxicam complex microparticles and administering the zinc meloxicam complex microparticles encapsulated in multivesicular liposome formulations and their use as medicaments are also provided.
    Type: Application
    Filed: July 2, 2020
    Publication date: December 24, 2020
    Inventors: Louie Daniel Garcia, Stephanie Kurz, Soroush Ardekani, Kathleen Dunne Albright Los, Katherine Stone, Ernest G. Schutt, Vladimir Kharitonov
  • Patent number: 10709665
    Abstract: Embodiments of the present disclosure are related to multivesicular liposome formulations encapsulating zinc meloxicam complex microparticles. Methods of making the zinc meloxicam complex microparticles and administering the zinc meloxicam complex microparticles encapsulated in multivesicular liposome formulations and their use as medicaments are also provided.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: July 14, 2020
    Assignee: Pacira Pharmaceuticals, Inc.
    Inventors: Louie Daniel Garcia, Stephanie Kurz, Soroush Ardekani, Kathleen Dunne Albright Los, Katherine Stone, Ernest G. Schutt, Vladimir Kharitonov
  • Patent number: 10383510
    Abstract: An implant delivery system can be configured to deliver an inflatable implant into a bladder via a urethra. The delivery system can comprise an elongate tubular body, an inflation tube and an implant decoupler. The tubular body can comprise a central lumen configured to hold an inflatable implant in an initial un-inflated state for delivery of the implant into the bladder. A method of use can include passing a distal tip of the elongate tubular body into the bladder. The implant can be inflated and released into the bladder.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: August 20, 2019
    Assignee: SOLACE THERAPEUTICS, INC.
    Inventors: Ernest G. Schutt, Kevin G. Connors, John Gillespie, Jr., Peter Dayton
  • Publication number: 20180161275
    Abstract: Embodiments of the present disclosure are related to multivesicular liposome formulations encapsulating zinc meloxicam complex microparticles. Methods of making the zinc meloxicam complex microparticles and administering the zinc meloxicam complex microparticles encapsulated in multivesicular liposome formulations and their use as medicaments are also provided.
    Type: Application
    Filed: November 17, 2017
    Publication date: June 14, 2018
    Inventors: Kathleen Dunne Albright Los, Louie Daniel Garcia, Stephanie Kurz, Katherine Stone, Ernest G. Schutt, Vladimir Kharitonov
  • Publication number: 20170127929
    Abstract: An implant delivery system can be configured to deliver an inflatable implant into a bladder via a urethra. The delivery system can comprise an elongate tubular body, an inflation tube and an implant decoupler. The tubular body can comprise a central lumen configured to hold an inflatable implant in an initial un-inflated state for delivery of the implant into the bladder. A method of use can include passing a distal tip of the elongate tubular body into the bladder. The implant can be inflated and released into the bladder.
    Type: Application
    Filed: October 14, 2016
    Publication date: May 11, 2017
    Inventors: Ernest G. Schutt, Kevin G. Connors, John Gillespie, Peter Dayton
  • Patent number: 9554993
    Abstract: A pulmonary delivery medicament comprises a plurality of particulates, the particulates comprising a structural matrix and a water insoluble and/or crystalline active agent. The particulates have a geometric diameter of 0.5 to 50 ?m. The water insoluble active agent can be a fungicide, antibiotic, budesonide. A method of making the medicament comprises forming a liquid feedstock, and forming a feedstock suspension by suspending in the liquid feedstock, the active agent and an excipient capable of forming a structural matrix, such as a phospholipid. The feedstock suspension is spray dried to produce the particulates.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: January 31, 2017
    Assignee: Novartis AG
    Inventors: Thomas E. Tarara, Jeffrey G. Weers, Alexey Kabalnov, Ernest G. Schutt, Luis A. Dellamary
  • Patent number: 9498195
    Abstract: An implant for use in a human or animal body can include a flexible housing with an outer wall and having a chamber therein. The implant can have at least one high vapor pressure medium within the chamber. The at least one high vapor pressure medium can have a combined vapor pressure equal to or greater than about the average value of the hydrostatic pressure of the implantation site plus the skin tension of the housing minus the gas tension of the dissolved gasses present at the implantation site.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: November 22, 2016
    Assignee: AttenueX Technologies, Inc.
    Inventors: Ernest G. Schutt, Kevin G. Connors, John Gillespie, Jr., Peter Dayton
  • Patent number: 9439862
    Abstract: Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation. The powders are hollow and porous and are preferably administered via inhalation.
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: September 13, 2016
    Assignee: Novartis AG
    Inventors: Jeffry G Weers, Thomas E Tarara, Luis A Dellamary, Ernest G Schutt
  • Publication number: 20140377361
    Abstract: A microparticle for drug delivery comprises an active agent and an excipient, the excipient comprising a metal ion-lipid complex. The metal ion is chosen from the group consisting of lanthanide metals, actinide metals, group IIa and IIIb metals, transition metals or mixtures thereof. The lipid comprises a phospholipid. The complex results in a glass transition temperature increase of the microparticle.
    Type: Application
    Filed: September 5, 2014
    Publication date: December 25, 2014
    Applicant: NOVARTIS AG
    Inventors: Luis A. DELLAMARY, Jean RIESS, Ernest G. SCHUTT, Jeffry G. WEERS, Thomas E. TARARA
  • Patent number: 8877162
    Abstract: A microparticle for drug delivery comprises an active agent and an excipient, the excipient comprising a metal ion-lipid complex. The metal ion is chosen from the group consisting of lanthanide metals, actinide metals, group IIa and IIIb metals, transition metals or mixtures thereof. The lipid comprises a phospholipid. The complex results in a glass transition temperature increase of the microparticle.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: November 4, 2014
    Assignee: Novartis AG
    Inventors: Luis A. Dellamary, Jean Reiss, Ernest G. Schutt, Jeffry G. Weers, Thomas E. Tarara
  • Publication number: 20140212504
    Abstract: Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation. The powders are hollow and porous and are preferably administered via inhalation.
    Type: Application
    Filed: April 2, 2014
    Publication date: July 31, 2014
    Inventors: Jeffry G. WEERS, Thomas E. TARARA, Luis A. DELLAMARY, Jean G. RIESS, Ernest G. SCHUTT
  • Patent number: 8709484
    Abstract: Phospholipid based powders for drug delivery applications are disclosed. The powders may include a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation. The powders are hollow and porous and are preferably administered via inhalation.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: April 29, 2014
    Assignee: Novartis AG
    Inventors: Jeffry G. Weers, Thomas E. Tarara, Luis A. Dellamary, Jean G. Riess, Ernest G. Schutt
  • Publication number: 20140081076
    Abstract: An implant delivery system can be configured to deliver an inflatable implant into a bladder via a urethra. The delivery system can comprise an elongate tubular body, an inflation tube and an implant decoupler. The tubular body can comprise a central lumen configured to hold an inflatable implant in an initial un-inflated state for delivery of the implant into the bladder. A method of use can include passing a distal tip of the elongate tubular body into the bladder. The implant can be inflated and released into the bladder.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: ATTENUEX TECHNOLOGIES, INC.
    Inventors: Ernest G. Schutt, Kevin G. Connors, John Gillespie, JR., Peter Dayton
  • Patent number: 8574146
    Abstract: An implant for use in a human or animal body can include a flexible housing with an outer wall and having a chamber therein. The implant can have at least one high vapor pressure medium within the chamber. The at one high vapor pressure medium can have a combined vapor pressure equal to or greater than about the average value of the hydrostatic pressure of the implantation site plus the skin tension of the housing minus the gas tension of the dissolved gasses present at the implantation site.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: November 5, 2013
    Assignee: AttenueX Technologies, Inc.
    Inventors: John Gillespie, Jr., Kevin G. Connors, Ernest G. Schutt, Peter Dayton