Patents by Inventor Erning Xia

Erning Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reversible gelling system for ocular drug delivery
    Publication number: 20020114778
    Abstract: The invention provides an ophthalmic aqueous composition for topical administration, comprising:
    Type: Application
    Filed: December 6, 2000
    Publication date: August 22, 2002
    Inventors: Erning Xia, Richard V. Smerbeck
  • Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by tyloxapol
    Patent number: 6369112
    Abstract: The present invention is directed to a biguanide-containing disinfecting solution containing tyloxapol in combination with a poloxamine for stabilizing the biguanide, which is especially useful for contact-lens solutions that provide enhanced disinfecting and enhanced cleaning efficacy. The method of the present invention comprises cleaning and disinfecting a contact lens with the above-described solution.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: April 9, 2002
    Assignee: Bausch & Lomb Incorporated
    Inventor: Erning Xia
  • High osmolyte cleaning and disinfection method and solution for contact lenses
    Publication number: 20020004466
    Abstract: Contact lens cleaning compositions comprising preserved surfactant-containing solutions of a poly(oxypropylene)-poly(oxyethylene) adduct of ethylene diamine having a molecular weight from about 7500 to as high as 27,000 wherein at least 40 weight percent of the adduct is poly(oxyethylene) hydrophilic units. The solutions are effective in removing protein/lipid tear film deposits on both hard and soft contact lenses while providing a prophylactic-like action in retarding the formation of subsequent tear film deposits. The compositions provide effective cleaning and conditioning action using both ambient and high temperature disinfection methods.
    Type: Application
    Filed: February 13, 2001
    Publication date: January 10, 2002
    Inventors: Erning Xia, Christine E. Soltys-Robitaille, Lisa C. Simpson
  • Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant stabilized by a poloxamine
    Patent number: 6309596
    Abstract: The present invention is directed to a biguanide-containing disinfecting solution containing a particular type of poloxamine for stabilizing a polymeric biguanide. The poloxamine surfactant comprises at least about 90 weight percent of poly(oxyethylene) and poly(oxypropylene) segments, in one or more copolymer chains, wherein the weight average molecular weight of said surfactant is from about 10,000 to about 30,000 and wherein at least about 70 weight percent of said poly(oxyethylene) and poly(oxypropylene) segments are poly(oxyethylene) segments, and wherein the HLB value is at least 27. The method of the present invention comprises cleaning and disinfecting a contact lens with the above-described solution. Products according to the present invention provide enhanced cleaning while maintaining biocidal efficacy.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: October 30, 2001
    Assignee: Bausch & Lomb Incorporated
    Inventors: Erning Xia, David J. Heiler
  • Treatment of contact lenses with aqueous solution comprising a carbonate salt for enhanced cleaning
    Patent number: 6309658
    Abstract: The present invention provides methods and compositions for cleaning and disinfecting contact lenses, which compositions comprise a carbonate or bicarbonate salt, a non-carbonate buffer system, an antimicrobial agent, and a non-ionic surfactant. Products according to the present invention, especially multi-purpose solutions, provide simultaneous disinfection and cleaning of contact lenses including the prevention or removal of protein and lipid deposits and other debris.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: October 30, 2001
    Assignee: Bausch & Lomb Incorporated
    Inventors: Erning Xia, Lisa C. Simpson, John Denick, Jr.
  • Compositions comprising polyquaterniums in combination with polymeric biguanides for disinfecting contact lenses
    Patent number: 6153568
    Abstract: The present invention is directed to an ophthalmically safe disinfecting solution for contact lenses comprising the combination of a polymeric biguanide and a polyquaternium polymer of a substituted or unsubstituted vinylimidazole or its vinylimidazoliuum salt, which copolymer has a weight average molecular weight of 5,000 to 5,000,000. The invention is also directed to an improved method of disinfecting a contact lens.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: November 28, 2000
    Inventors: David J. McCanna, Stephen E. Maier, David J. Heiler, Susan P. Spooner, Erning Xia
  • Treatment of contact lenses with aqueous solution comprising a biguanide disinfectant and a complementary phosphate-borate buffer system
    Patent number: 6143244
    Abstract: The present invention is directed to aqueous biguanide-containing disinfecting solutions containing an improved buffer system including both a phosphate and borate buffer. Preferred embodiments of the invention include methods and compositions for simultaneously cleaning and disinfecting contact lenses.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: November 7, 2000
    Assignee: Bausch & Lomb Incorporated
    Inventors: Erning Xia, Jill Short Rogalskyj, Lisa C. Simpson