Patents by Inventor Eswaraiah Sajja

Eswaraiah Sajja has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABLE N-((1R,2R)-1-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)-1-HYDROXY-3-(PYRROLIDIN-1-YL)PROPAN-2-YL) OCTANAMIDE (2R,3R)-2,3-DIHYDROXYSUCCINATE PREMIX AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20200306225
    Abstract: The present invention related to stable N-((1R,2R)-1-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl) -1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl) octanamide (2R,3R)-2,3-dihydroxysuccinate premix of formula (Ia) and its process for preparation thereof.
    Type: Application
    Filed: October 26, 2018
    Publication date: October 1, 2020
    Inventors: Thirumalai Rajan SRINIVASAN, Eswaraiah SAJJA, Venkat Redby GHOJALA, Rajeshwar Reddy SAGYAM, Venkat Reddy MALLEPALLY, Ravinder reddy KOPPERA, Adilakshmi SINGAVARAPU, Srinivasulu RANGINENI
  • SOLID STATE FORMS OF 5-CHLORO-6-[(2-IMINOPYRROLIDIN-1-YL)METHYL]PYRIMIDINE-2,4-(1H,3H)-DIONE HYDROCHLORIDE AND THEIR PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20200283413
    Abstract: The present invention relates to solid state forms of 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione hydrochloride compound of formula-1a and their processes for the preparation thereof and an improved process for the preparation of 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione hydrochloride. The present inventors also provides an amorphous polymorph of the combination drug consisting of 2?-deoxy-5-(trifluoromethyl) uridine and 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4-(1H,3H)-dione monohydrochloride and its process for the preparation.
    Type: Application
    Filed: September 7, 2018
    Publication date: September 10, 2020
    Applicant: MSN LABORATORIES PRIVATE LIMITED, R&D CENTER
    Inventors: Thirumalai Rajan SRINIVASAN, Eswaraiah SAJJA, Venkat Reddy GHOJALA, Rajeshwar Reddy SAGYAM, Srinivasulu RANGINENI, Rajashekar KOMMERA, Markandeya BEKKAM
  • Process for the preparation of Trisodium (4- {[1S,3R)-1-([1,1?-biphenyl]-4-ylmethyl)-4-ethoxy-3-methyl-4-oxobutyl]amino}-4-oxobutanoate)-(N-petanoyl-N-{[2?-(1H-tetrazol-1-1D-5-yl)[1,1?-biphenyl]-4-yl]methyl}- L-valinate) and its polymorphs thereof
    Patent number: 10703731
    Abstract: The present invention relates to a process for the preparation of Trisodium (4-{[(1S.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: July 7, 2020
    Assignee: MSN LABORATORIES PRIVATE LIMITED
    Inventors: Thirumalai Rajan Srinivasan, Eswaraiah Sajja, Rajeshwar Reddy Sagyam, Rajesham Boge, Chkradhar Nandigama, Srinivasa Rao Ambati
  • PROCESS FOR THE PREPARATION OF 5-(4-CYANOPHENOXY)-1,3-DIHYDRO-1-HYDROXY-[2,1]-BENZOXABOROLE AND POLYMORPHS THEREOF
    Publication number: 20200190120
    Abstract: The present invention relates to process for the preparation of 5-(4-cyano phenoxy)- 1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole represented by the following structural formula-1 and polymorphs thereof. The present invention also relates to salts of 5-(4-cyano phenoxy)-1,3-dihydro-1-hydroxy-[2,1]-benzoxaborole and process for their preparation and their use in the preparation of pure compound of the formula-1.
    Type: Application
    Filed: May 23, 2018
    Publication date: June 18, 2020
    Applicant: MSN LABORATORIES PRIVATE LIMITED, R&D CENTER
    Inventors: Thirumalai Rajan SRINIVASAN, Eswaraiah SAJJA, Venkat Reddy GHOJALA, Markandeya BEKKAM
  • SOLID STATE FORMS OF N-[2-[(I S)-1 -(3-ETHOXY-4-METHOXYPHENYL)-2-(METHYL SULFONYL)ETHYL]-2,3-DIHYDRO-1,3-DIOXO-L H-ISOINDOL-4-YL]ACETAMIDE AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20200109114
    Abstract: The present invention, relates to solid state forms of N-[2-[(1 S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide represented by the following structural formula-1 and process for their preparation. The present invention also relates to an improved process for the preparation of N-[2-[(1 S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide compound of formula-1 and intermediates thereof.
    Type: Application
    Filed: December 7, 2019
    Publication date: April 9, 2020
    Applicant: MSN LABORATORIES PRIVATE LIMITED, R&D CENTER
    Inventors: Thirumalai Rajan Srinivasan, Eswaraiah Sajja, Venkat Reddy Ghojala, Pradeep Rebelli
  • Process for the preparation of N-[4-[(3-chloro-4-fluoro phenyl) amino]-7-[[(3s-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyl amino)-(2E)-2-butenamide (2Z)-2-butenedioate (1:2) and its polymorphs thereof
    Patent number: 10550107
    Abstract: The present invention relates to an improved process for the preparation of N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethyl amino)-(2E)-2-butenamide (2Z)-2-butenedioate (1:2) represented by the following structural formula:
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: February 4, 2020
    Assignee: MSN LABORATORIES PRIVATE LIMITED
    Inventors: Thirumalai Rajan Srinivasan, Eswaraiah Sajja, Venkata Panakala Rao Gogulapati, Rajesham Boge
  • Solid state forms of N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide and process for preparation thereof
    Patent number: 10544097
    Abstract: The present invention, relates to solid state forms of N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide represented by the following structural formula-1 and process for their preparation. The present invention also relates to an improved process for the preparation of N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide compound of formula-1 and intermediates thereof.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: January 28, 2020
    Assignee: MSN LABORATORIES PRIVATE LIMITED
    Inventors: Thirumalai Rajan Srinivasan, Eswaraiah Sajja, Venkat Reddy Ghojala, Pradeep Rebelli
  • A PROCESS FOR THE PREPARATION OF D-GLUCITOL, 1,5-ANHYDRO-1-C-[4-CHLORO-3-[[4- [[(3S)-TETRAHYDRO-3-FURANYL]OXY]PHENYL]METHYL]PHENYL]-, ( 1 S)
    Publication number: 20200017483
    Abstract: The present invention relates to a process for the preparation of D-glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl)oxy)phenyl] methyl]phenyl]-, (IS) formula-1.
    Type: Application
    Filed: March 12, 2018
    Publication date: January 16, 2020
    Applicant: MSN LABORATORIES PRIVATE LIMITED, R&D CENTER
    Inventors: Thirumalai Rajan SRINIVASAN, Eswaraiah SAJJA, Venkata Panakala Rao GOGULAPATI, Rajeshwar Reddy SAGYAM, Mohammad Rafee SHAIK, Srinivasuslu RANGINENI
  • PROCESSES FOR THE PREPARATION OF 7-{4-[4-(1-BENZOTHIOPHEN-4-YL) PIPERAZIN-1-YL]BUTOXY}QUINOLIN-2(1H)-ONE
    Publication number: 20190359606
    Abstract: The Present Invention of relates to process for the preparation of 7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy}quinolin-2(1H)-one represented by the following structural formula-1.
    Type: Application
    Filed: November 7, 2017
    Publication date: November 28, 2019
    Applicant: MSN LABORATORIES PRIVATE LIMITED
    Inventors: Thirumalai Rajan SRINIVASAN, Eswaraiah SAJJA, Venkat Reddy GHOJALA, Rajashekar KOMMERA
  • PROCESS FOR THE PREPARATION OF 5-[[[(2S)-2-AMINO-3-[4-(AMINOCARBONYL)-2,6-DIMETHYLPHENYL]-1-OXOPROPYL] [(1S)-1-(4-PHENYL-1H-IMIDAZOL-2-YL)ETHYL]AMINO] METHYL-2-METHOXYBENZOIC ACID AND ITS POLYMORPHS THEREOF
    Publication number: 20190177281
    Abstract: The present invention relates to an improved process for the preparation of 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid compound of formula-1, and polymorphs thereof, the compound of formula-1 is further represented by the following structural formula:
    Type: Application
    Filed: May 2, 2017
    Publication date: June 13, 2019
    Inventors: Srinivasan Thirumalai RAJAN, Eswaraiah SAJJA, Rajeshwar Reddy SAGYAM, Prabhakar MACHARLA, Rajesham BOGE
  • PROCESS FOR THE PREPARATION OF TRISODIUM (4-{[1S,3R)-1-([1,1'-BIPHENYL]-4-YLMETHYL)-4-ETHOXY-3-METHYL-4-OXOBUTYL]AMINO}-4-OXOBUTANOATE)-(N-PETANOYL-N-{[2'-(1H-TETRAZOL-1-1D-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL}- L-VALINATE) AND ITS POLYMORPHS THEREOF
    Publication number: 20190077775
    Abstract: The present invention relates to a process for the preparation of Trisodium (4-{[(1S.
    Type: Application
    Filed: March 6, 2017
    Publication date: March 14, 2019
    Inventors: Thirumalai Rajan SRINIVASAN, Eswaraiah SAJJA, Rajeshwar Reddy SAGYAM, Rajesham BOGE, Chkradhar NANDIGAMA, Srinivasa Rao AMBATI
  • Polymorphic forms of tadalafil
    Patent number: 8063214
    Abstract: A process for preparing crystalline Form A of tadalafil (I), comprising crystallization from a solution of tadalafil in a solvent comprising a C3-C7 ester, a ketone, dimethylformamide, dimethylsulfoxide, ethanol, acetonitrile, a chlorinated hydrocarbon, t-butanol, N,N-dimethylacetamide, dioxane, N-methyl pyrrolidone, or a mixture of any two or more thereof.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: November 22, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Eswaraiah Sajja, Venkata Naga Kali Vara Prasada Raju Vetukuri, Srinivas Reddy Ningam, Ravindra Vedantham, Rajyalakshmi Bodepudi
  • Polymorphic forms of vardenafil
    Patent number: 7977478
    Abstract: Crystalline polymorphic forms of vardenafil and vardenafil hydrochloride, and processes for preparing them.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: July 12, 2011
    Assignees: Dr. Reddy's Laboratories Limited, Dr. Reddy's Laboratories, Inc.
    Inventors: Eswaraiah Sajja, Ravindar Reddy Koppera, Satyanarayana Revu, Venkata Reddy Vajrala, Vijayapal Reddy Kanumathi
  • Process for making crystalline form I of clopidogrel hydrogen sulphate
    Patent number: 7772398
    Abstract: A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: August 10, 2010
    Assignees: Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Limited
    Inventors: Eswaraiah Sajja, Raghupathi Reddy Anumula, Bhaskara rao Venkata Uppala
  • POLYMORPHIC FORMS OF TADALAFIL
    Publication number: 20090131667
    Abstract: Polymorphic forms of tadalafil, and processes for their preparation.
    Type: Application
    Filed: October 26, 2005
    Publication date: May 21, 2009
    Inventors: Eswaraiah Sajja, Venkata Naga Kali Vara Prasada Raju Vetukuri, Srinivas Reddy Ningam, Ravindra Vedantham, Rajyalakshmi Bodepudi
  • PROCESS FOR PREPARING CLOPIDOGREL
    Publication number: 20070225320
    Abstract: A process for preparing clopidogrel or a salt thereof.
    Type: Application
    Filed: March 26, 2007
    Publication date: September 27, 2007
    Inventors: Eswaraiah Sajja, Raghupathi Reddy Anumula, Goverdhan Gilla, Lokeswara Rao Madivada
  • POLYMORPHIC FORMS OF VARDENAFIL
    Publication number: 20070197535
    Abstract: Crystalline polymorphic forms of vardenafil and vardenafil hydrochloride, and processes for preparing them.
    Type: Application
    Filed: September 27, 2006
    Publication date: August 23, 2007
    Inventors: Eswaraiah Sajja, Ravindar Koppera, Satyanarayana Revu, Venkata Vajrala, Vijayapal Kanumathi
  • PRIMIDONE PROCESS AND COMPOSITIONS
    Publication number: 20070149779
    Abstract: The present invention relates to a process for the preparation of primidone. It also relates to compositions comprising primidone of desired particle size distribution, processes for the preparation of such particles and processes for the preparation of the compositions.
    Type: Application
    Filed: December 19, 2006
    Publication date: June 28, 2007
    Inventors: Eswaraiah Sajja, Sudeep Agrawal, Alagumurugan Alagarsamy, Ravindar Koppera, Madhusudhan Ganta, Ramesh Konda, Ganesh Varanasi, Indu Bhushan, Mailatur Mohan, Asif Anwar
  • NON-BENZODIAZEPINE HYPNOTIC COMPOSITIONS
    Publication number: 20070098788
    Abstract: Pharmaceutical compositions comprising non-benzodiazepine hypnotic drugs or their pharmaceutically acceptable salts, solvates, enantiomers or mixtures and processes for preparing the same. The invention also includes immediate release and extended release pharmaceutical compositions comprising non-benzodiazepine hypnotic drugs, useful for sleep induction and sleep maintenance.
    Type: Application
    Filed: October 26, 2006
    Publication date: May 3, 2007
    Inventors: Subhash Gore, Sudeep Agrawal, Abhijeet Upadhye, Srinivasulu Rangineni, Sivakumar Bommareddy, Srinivas Gade, Basappa Nagaraj, Gautam Bakshi, Surjit Das, Satish Jain, Surya Devarakonda, Bharath Deevireddy, Eswaraiah Sajja, Venkata Naga Kali Veturi, Sreenadhacharyulu Kandala, Gurvinder Singh, Indu Bhushan, Mailatur Mohan
  • PROCESS FOR PREPARING LACIDIPINE
    Publication number: 20070043088
    Abstract: A process for preparing lacidipine, comprising reacting a t-butoxy carbonyl methyl aryl phosphonium halide with o-phthalaldehyde, and further reacting a product comprising (E)-3-(2-formylphenyl)-2-propenoic acid, 1,1-dimethyl ethyl ester, without isolation, with ethyl-3-amino crotonate.
    Type: Application
    Filed: August 15, 2006
    Publication date: February 22, 2007
    Inventors: Eswaraiah Sajja, Venkata Naga Kali Vara Prasada Vetukuri, Srinivas Ningam, Ravindra Vedantham