Patents by Inventor Eugene D. Kwon

Eugene D. Kwon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • B7-H1 AND B7-H4 IN CANCER
    Publication number: 20160153996
    Abstract: Methods of determining prognosis of a subject with cancer or determining risk of cancer progression by assessing expression of B7-H4, or B7-H1 and B7-H4 in combination.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 2, 2016
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan M. Harrington, Robert H. Thompson, Lieping Chen, Haidong Dong, Christine M. Lohse
  • Methods and materials for treating cancer
    Patent number: 9302005
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: April 5, 2016
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • B7-H4 EXPRESSION ON TUMOR VASCULATURE
    Publication number: 20160051675
    Abstract: Methods of evaluating patients by assessing expression of B7-H4 in the vasculature are described.
    Type: Application
    Filed: August 31, 2015
    Publication date: February 25, 2016
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Eugene D. Kwon, John C. Cheville
  • B7-H4 expression on tumor vasculature
    Patent number: 9121853
    Abstract: Methods of evaluating patients by assessing expression of B7-H4 in the vasculature are described.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: September 1, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Eugene D. Kwon, John Cheville
  • Soluble B7-H1
    Publication number: 20150111232
    Abstract: This document features methods of evaluating mammals by assessing expression of B7-H1 in a body fluid.
    Type: Application
    Filed: November 25, 2014
    Publication date: April 23, 2015
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Eugene D. Kwon, Haidong Dong, Xavier Frigola Baro, Brant A. Inman
  • COSTIMULATORY B7-H1 IN RENAL CELL CARCINOMA PATIENTS: INDICATOR OF TUMOR AGGRESSIVENESS AND POTENTIAL THERAPEUTIC TARGET
    Publication number: 20150044165
    Abstract: The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with B7-H1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of B7-H1.
    Type: Application
    Filed: April 29, 2014
    Publication date: February 12, 2015
    Inventors: Lieping CHEN, Scott E. STROME, Eugene D. KWON
  • B7-H1 AND B7-H4 IN CANCER
    Publication number: 20140335541
    Abstract: Methods of determining prognosis of a subject with cancer or determining risk of cancer progression by assessing expression of B7-H4, or B7-H1 and B7-H4 in combination.
    Type: Application
    Filed: July 10, 2014
    Publication date: November 13, 2014
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan M. Harrington, Robert H. Thompson, Lieping Chen, Haidong Dong, Christine M. Lohse
  • B7-H1 AND SURVIVIN IN CANCER
    Publication number: 20140329248
    Abstract: Methods of determining prognosis of a subject with cancer by assessing expression of B7-H1 and survivin in combination.
    Type: Application
    Filed: July 10, 2014
    Publication date: November 6, 2014
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan M. Harrington, Robert H. Thompson, Haidong Dong, Christine M. Lohse, Alexander S. Parker
  • METHODS AND MATERIALS FOR TREATING CANCER
    Publication number: 20140271674
    Abstract: This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1+/CD11ahigh CD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.
    Type: Application
    Filed: February 27, 2014
    Publication date: September 18, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Haidong Dong, Eugene D. Kwon, Svetomir N. Markovic, Christopher J. Krco
  • B7-H1 and methods of diagnosis, prognosis, and treatment of cancer
    Patent number: 8747833
    Abstract: The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with B7-H1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of B7-H1.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: June 10, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Lieping Chen, Scott E. Strome, Eugene D. Kwon
  • METHODS FOR REDUCING GRANULOMATOUS INFLAMMATION
    Publication number: 20130251736
    Abstract: This document provides methods and materials for reducing bacterial induced granulomatous inflammation in a mammal using agents that reduce B7-H1 expression or activity.
    Type: Application
    Filed: May 15, 2013
    Publication date: September 26, 2013
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Eugene D. Kwon, John C. Cheville, Thomas J. Sebo, Brant A. Inman
  • B7-H1 AND METHODS OF DIAGNOSIS, PROGNOSIS, AND TREATMENT OF CANCER
    Publication number: 20110200620
    Abstract: The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with B7-H1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of B7-H1.
    Type: Application
    Filed: January 24, 2011
    Publication date: August 18, 2011
    Inventors: Lieping CHEN, Scott E. STROME, Eugene D. KWON
  • B7-H1 and methods of diagnosis, prognosis, and treatment of cancer
    Patent number: 7892540
    Abstract: The invention features methods of diagnosis by assessing B7-H1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with B7-H1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of B7-H1.
    Type: Grant
    Filed: October 6, 2005
    Date of Patent: February 22, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Lieping Chen, Scott E. Strome, Eugene D. Kwon
  • METHODS FOR REDUCING GRANULOMATOUS INFLAMMATION
    Publication number: 20110020325
    Abstract: This document provides methods and materials for reducing bacterial induced granulomatous inflammation in a mammal using agents that reduce B7-H1 expression or activity.
    Type: Application
    Filed: February 27, 2009
    Publication date: January 27, 2011
    Inventors: Eugene D. Kwon, John C. Cheville, Thomas J. Sebo, Brant A. Inman
  • B7-H3 IN CANCER
    Publication number: 20100203035
    Abstract: Methods of determining the prognosis of a subject with cancer and determining risk of cancer progression by assessing expression of B7-H3. Methods of reducing B7-H3 levels and/or activity.
    Type: Application
    Filed: February 12, 2008
    Publication date: August 12, 2010
    Inventors: Eugene D. Kwon, Christine M. Lohse, Yuri Sheinin, Timothy H. Roth, Susan Kuntz
  • B7-H1 AND SURVIVIN IN CANCER
    Publication number: 20100015642
    Abstract: Methods of determining prognosis of a subject with cancer by assessing expression of B7-H1 and survivin in combination.
    Type: Application
    Filed: January 5, 2007
    Publication date: January 21, 2010
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan Kuntz, Robert H. Thompson, Haidong Dong, Christine M. Lohse, Alexander S. Parker
  • B7-H1 AND B7-H4 IN CANCER
    Publication number: 20090215084
    Abstract: Methods of determining prognosis of a subject with cancer or determining risk of cancer progression by assessing expression of B7-H4, or B7-H1 and B7-H4 in combination.
    Type: Application
    Filed: January 5, 2007
    Publication date: August 27, 2009
    Inventors: Eugene D. Kwon, John C. Cheville, Amy Krambeck, Susan Kuntz, Robert H. Thompson, Lieping Chen, Haidong Dong, Christine M. Lohse
  • Soluble B7-H1
    Publication number: 20090176317
    Abstract: This document features methods of evaluating mammals by assessing expression of B7-H4 in the vasculature.
    Type: Application
    Filed: October 20, 2008
    Publication date: July 9, 2009
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Eugene D. Kwon, Haidong Dong, Xavier Frigola Baro, Brant A. Inman
  • B7-H4 EXPRESSION ON TUMOR VASCULATURE
    Publication number: 20070218032
    Abstract: Methods of evaluating patients by assessing expression of B7-H4 in the vasculature are described.
    Type: Application
    Filed: March 20, 2007
    Publication date: September 20, 2007
    Inventors: Eugene D. Kwon, John Cheville