Abstract: The present disclosure relates to SH3YL1 monoclonal antibodies and compositions comprising the SH3YL1 monoclonal antibodies. The disclosure also relates to isolated nucleic acid molecules encoding the SH3YL1 antibodies, vectors comprising the nucleic acid molecules, and host cells comprising the vectors. Also disclosed are methods of modulating an immune response, methods of treating diabetic nephropathy, and methods of treating non-alcoholic steatosis hepatitis comprising administering the SH3YL1 antibodies. Also disclosed are methods of treating acute kidney injury and methods of treating inflammatory bowel disease comprising administering the SH3YL1 antibodies.

Abstract: The electrochemical energy conversion system of the present disclosure includes an anode, a cathode, and an ion exchange membrane including a polymer having an aromatic polymer chain and an alkylated substrate including an alkyl chain, and at least one ionic group. The alkylated substrate is bound to at least one aromatic group in the polymer chain via Friedel-Crafts alkylation of the at least one aromatic group. The alkylation reaction utilizes a haloalkylated tertiary alcohol or a haloalkylated alkene as a precursor. In the presence of an acid catalyst, a carbocation is generated in the precursor which reacts with the aromatic rings of the polymer chain. The at least one ionic group is then replaced with a desired cationic or anionic group using a substitution reaction. The membranes exhibit advantageous stability achieved through a simplified and scalable reaction scheme.

Abstract: A positive electrode active material for a secondary battery includes a lithium composite transition metal oxide including nickel (Ni), cobalt (Co), and manganese (Mn), wherein the lithium composite transition metal oxide has a layered crystal structure of space group R3m, includes the nickel (Ni) in an amount of 60 mol % or less based on a total amount of transition metals, includes the cobalt (Co) in an amount greater than an amount of the manganese (Mn), and is composed of single particles.

Abstract: A positive electrode active material precursor having a uniform particle size distribution and represented by Formula 1, wherein a percentage of fine powder with an average particle diameter (D50) of 1 ?m or less is generated when the positive electrode active material precursor is rolled at 2.5 kgf/cm2 is less than 1%, and an aspect ratio is 0.93 or more, and a method of preparing the positive electrode active material precursor [NixCoyM1zM2w](OH)2 ??[Formula 1] in Formula 1, 0.5?x<1, 0<y?0.5, 0<z?0.5, and 0?w?0.1, M1 includes at least one selected from the group consisting of Mn and Al, and M2 includes at least one selected from the group consisting of Zr, B, W, Mo, Cr, Nb, Mg, Hf, Ta, La, Ti, Sr, Ba, Ce, F, P, S, and Y. A method of preparing the positive electrode active material precursor is also provided.

Abstract: The present invention relates to a novel chimeric antigen receptor comprising a CD99 region which participates in immune synapse stabilization as a backbone of the chimeric antigen receptor, an immune cell comprising the same, and the uses thereof. CD99-based CAR-T cells are capable of forming very stable immune synapses with tumor cells compared to conventional backbone-based CAR-T cells and can exhibit improved tumor therapeutic efficiency, so they can be useful for immune cell therapy for the treatment of cancer.

Abstract: Disclosed is an interface system including a first neuron cluster that outputs a first neuron signal including a first neuron request and first neuron data by performing a first arithmetic operation, and a first interface circuit that stores the first neuron data and outputs a first response, in response to the first neuron request. The first neuron cluster outputs a second neuron signal including a second neuron request and second neuron data by performing a second arithmetic operation, in response to the first response. Before the first data is transmitted to a second neuron cluster different from the first neuron cluster, the first interface circuit outputs the first response in response to a fact that the first neuron data is stored.

Abstract: Provided is a method for recovering and reusing an active material from a positive electrode scrap.

Abstract: The present disclosure relates to a device and a method for adjusting a pulse width of a laser beam by using the plasma generated by being induced from laser as a shutter, and more particularly, to a device and a method for adjusting a laser pulse width, which can precisely and quickly adjust the laser pulse width by dividing the laser generated from a laser light source into a target pulse and a shutter pulse; converting the optical path of the divided laser; and chopping the target pulse by using the plasma induced from the shutter pulse as an optical shutter in a cell having adjustable internal pressure.

Abstract: A shift-by-wire system physically prevents shifting to the R/N/D gear position and shifting to the P gear position from being simultaneously performed. The shift-by-wire system includes a body configured to have a Hall sensor provided therein, a knob installed so as to be rotatable around an axis of the body, a button assembly moving in an axial direction of the body and having a magnet provided to sense rotated and moved states thereof using the Hall sensor and rotate together with the knob, and a concurrent operation limiting unit to mechanically limit movement of the button assembly in a state in which the knob is manipulated so as to be rotated, and to mechanically limit rotation of the knob in a state in which the button assembly is manipulated so as to be moved.

Abstract: A shift-by-wire system physically prevents shifting to the R/N/D gear position and shifting to the P gear position from being simultaneously performed. The shift-by-wire system includes a body configured to have a Hall sensor provided therein, a knob installed so as to be rotatable around an axis of the body, a button assembly moving in an axial direction of the body and having a magnet provided to sense rotated and moved states thereof using the Hall sensor and rotate together with the knob, and a concurrent operation limiting unit to mechanically limit movement of the button assembly in a state in which the knob is manipulated so as to be rotated, and to mechanically limit rotation of the knob in a state in which the button assembly is manipulated so as to be moved.

Abstract: The present invention relates to a radioactive chemical waste treatment apparatus including an adsorption unit including an radioactive chemical waste adsorption member for adsorbing and separating radioactive chemical wastes from radioactive chemical waste-containing fluid, and a regeneration unit which is in fluidic communication with the adsorption unit and is for regenerating the radioactive chemical waste adsorption member by desorbing the radioactive chemical wastes from the adsorption member with the radioactive chemical wastes adsorbed thereonto, and to a radioactive chemical waste treatment method including (A) adsorbing radioactive chemical wastes onto a radioactive chemical waste adsorption member and separating the radioactive chemical wastes from a radioactive chemical waste-containing fluid, and (B) desorbing the radioactive chemical wastes from the radioactive chemical waste adsorption member with the radioactive chemical wastes adsorbed thereonto, and regenerating the radioactive chemical wast

Abstract: An image sensor package is provided. The image sensor package includes an image sensor, a substrate on which the image sensor is disposed on a first surface of the substrate and a receiving groove is disposed in a second surface of the surface, and a heat dissipation element including a heat absorption portion configured to absorb heat from a contact surface and a heat emission portion configured to emit heat absorbed by the heat absorption portion, and coupled to the second surface of the substrate, wherein, in the heat dissipation element, at least a portion of the heat absorption portion is accommodated in the receiving groove and coupled to the substrate.

Abstract: The present invention relates to a method for measuring radioactivity of radioactive waste, the method comprising an adsorption step (A) of selectively adsorbing a radioactive substance comprising at least one from among radioactive iodine and radioactive cesium from radioactive waste containing radioactive substances on an adsorption member for adsorbing a radioactive substance, and a measurement step (B) of measuring radioactivity of the radioactive substance.

Abstract: Disclosed herein is a composition for enhancing skin elasticity or improving skin wrinkles. In one aspect, 2-isopropylmalic acid or a salt, hydrate or solvate thereof, which is an active ingredient of the present disclosure, activates skin primary cilia and inhibits the expression of MMP-1 to enhance skin elasticity and improve skin wrinkles. In addition, in one aspect, 2-isopropylmalic acid or a salt, hydrate or solvate thereof, which is an active ingredient of the present disclosure, is a safe material and has the advantage that it can be treated in the living body in various forms such as cosmetics and food.

Abstract: A regenerative braking system and method include: a regenerative braking determination unit configured to determine whether or not a vehicle satisfies an entry condition for regenerative braking based on information collected by the vehicle; a calculation unit configured to calculate a hydraulic braking torque according to a pressure of a master cylinder and a target amount of a regenerative braking torque varied according to the pressure of the master cylinder, if the vehicle satisfies the entry condition; and a controller configured to perform braking of the vehicle based on the target amount of the regenerative braking torque and the hydraulic braking torque.

Abstract: The present invention relates to a microparticle-structured thickener having improved sensation of use. Even when swelling in an aqueous phase, the thickener according to the present invention shows the advantage of retaining the form of particles as well as appearing transparent and being high in stability because the particles disperse homogeneously.

Abstract: A camera module includes a substrate, an image sensor disposed on the substrate, a housing to accommodate the image sensor, a filter configured to block an infrared wavelength of light incident on the image sensor and disposed on the housing, a gap maintaining member to maintain a gap between the substrate and the bottom housing, and a sealing member to connect the substrate to the housing and to surround the image sensor.

Abstract: A shift-by-wire system physically prevents shifting to the R/N/D gear position and shifting to the P gear position from being simultaneously performed. The shift-by-wire system includes a body configured to have a Hall sensor provided therein, a knob installed so as to be rotatable around an axis of the body, a button assembly moving in an axial direction of the body and having a magnet provided to sense rotated and moved states thereof using the Hall sensor and rotate together with the knob, and a concurrent operation limiting unit to mechanically limit movement of the button assembly in a state in which the knob is manipulated so as to be rotated, and to mechanically limit rotation of the knob in a state in which the button assembly is manipulated so as to be moved.

Abstract: A system for and a method of controlling driving of a continuously-operable electronic vacuum pump includes determining conditions for allowing and disallowing first and second electronic vacuum pumps to operate for each braking situation according to vehicle state information associated with braking. The first and second electronic vacuum pumps are driven individually or concurrently according to the determined braking situation. Thus, an optimal negative pressure optimal suitable for the vehicle state information is easily supplied to a booster.

Abstract: The present application relates to a frozen product for microwave cooking.