Abstract: The present invention relates to a method for producing fluorine-containing dialkyl carbonate compounds, which are suitable as non-aqueous solvents for non-aqueous electrolytes used in secondary batteries. When an alkyl chloroformate and an alcohol are reacted in the presence of an ether-containing imidazole derivative base, the reaction can be carried out at room temperature as compared with the prior art, and the products can be separated within a short time from the reactants. This is an economical process, and according to the present invention, it is possible to obtain alkyl carbonates containing fluorine atoms simply and without difficulty in the removal of solvents, salts formed during the reaction, and by-products.

Abstract: The present invention relates to a transformed human cell and a use thereof and, more particularly, to a cell transformed with a gene for coding an MHC I cell membrane receptor and an MHC II cell membrane receptor by using a gene expression suppressing system using a guide RNA, and a use thereof. Such a transformed cell can effectively exhibit the therapeutic effect of cells even in vivo, and cannot be removed by an in vivo immune response. Therefore, it is expected that a composition comprising the immunocyte as an active ingredient can be usefully used for the treatment of cancer, infectious diseases, degenerative diseases or immunological diseases.

Abstract: The disclosure is related to monitoring a legacy device using at least one smart device. A gateway of an automation system may monitor an operation status of a target legacy device located in a service area of an automation system using at least one of smart devices participating in the automation system. In order to monitor, a monitoring request may be received for monitoring the target legacy device from user equipment associated with a user. At least one of monitoring smart devices may be controlled for monitoring the target legacy device. Monitoring results may be received from the at least one of monitoring smart devices. The received monitoring results may be provided to the user through the user equipment using at least one of outputting monitoring smart devices.

Abstract: A pixel circuit includes a sensing block, a stimulation block, a first line control circuit, and a second line control circuit. The sensing block outputs biometric data of a biosignal in response to a first selection signal. The stimulation block radiates a stimulation signal in response to a second selection signal. The first line control circuit outputs the first selection signal for selecting the sensing block as a target sensing block, and outputs the second selection signal for selecting the stimulation block as a target stimulation block. The second line control circuit processes characteristic data associated with the biometric data and the stimulation signal.

Abstract: The present invention relates to a method for producing fluorine-containing dialkyl carbonate compounds, which are suitable as non-aqueous solvents for non-aqueous electrolytes used in secondary batteries. When an alkyl chloroformate and an alcohol are reacted in the presence of an ether-containing imidazole derivative base, the reaction can be carried out at room temperature as compared with the prior art, and the products can be separated within a short time from the reactants. This is an economical process, and according to the present invention, it is possible to obtain alkyl carbonates containing fluorine atoms simply and without difficulty in the removal of solvents, salts formed during the reaction, and by-products.

Abstract: The present disclosure relates to a shoelace adjusting device and a shoe including the same. The shoelace adjusting device and the shoe including the same based on an embodiment of the present disclosure include a motor configured to operate to adjust at least one part of the shoelace, a sensor including a motion sensor, and a processor configured to determine whether the shoe is being used in a running state, a walking state, or a sitting state based on sensing information from the motion sensor and to change a level for tightening the shoelace based on the respective states. Accordingly, the tightness of the shoelace may be automatically adjusted based on the state of the user wearing the shoes.

Abstract: Provided is an inhibitor of an indoleamine 2,3-dioxygenase (IDO) and/or tryptophan 2,3-dioxygenase (TDO) of formula (I) or a pharmaceutically acceptable salt thereof: in which W1, W2, W3, and W4, X, Y, Z1, Z2, and R1-7 are described herein. Further provided is a method of treating or preventing a IDO and/or TDO-mediated disease using an effective amount of the compound of formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: A method of preparing a difluorinated alcohol compound is provided. The difluorinated alcohol compound can be easily synthesized when an aldehyde and N-fluorobenzenesulfonimide are reacted in the presence of L-proline, and thus the method has advantage in that preparation processes are simple and reagents are economical and safe, compared to the related-art methods. Therefore, the preparation method can be effectively applied to prepare a difluorinated alcohol used in various applications for raw materials such as functional medicines, agricultural chemicals, polymerizable compounds, etc.

Abstract: The present invention relates to a method for preparing a spiro quaternary ammonium salt comprising reacting a cyclic secondary amine with a dihaloalkane in the presence of a basic resin. According to the preparation method of the present invention, a metal salt and halide ion are removed by filtration without any additional purification process, the spiro ammonium derivative compound can be obtained with high yield, and the resin can be reused through a simple treatment process.

Abstract: The present invention relates to a method for preparing a spiro quaternary ammonium salt comprising reacting a cyclic secondary amine with a dihaloalkane in the presence of a basic resin. According to the preparation method of the present invention, a metal salt and halide ion are removed by filtration without any additional purification process, the spiro ammonium derivative compound can be obtained with high yield, and the resin can be reused through a simple treatment process.

Abstract: The present disclosure may provide a mobile terminal including a body having a front surface, a rear surface and a lateral surface thereof, a display unit disposed on the front surface to display first screen information, a lateral touch sensing unit formed on the lateral surface adjacent to both edges of the display unit to receive a user's consecutive touch input, and a controller configured to control the display unit to display second screen information in one region on the display unit corresponding to a touch range of the consecutive touch input.

Abstract: Described embodiments provide managing data collected from machine 2 machine (M2M) devices. A plurality of M2M devices may be grouped based on a common interest and the same group authorization key may be assigned to M2M devices in the same device group. A data collecting terminal having a group authorization key may be allowed to collect data in M2M devices when the M2M devices have the same group authorization key.

Abstract: A method of preparing a difluorinated alcohol compound is provided. The difluorinated alcohol compound can be easily synthesized when an aldehyde and N-fluorobenzenesulfonimide are reacted in the presence of L-proline, and thus the method has advantage in that preparation processes are simple and reagents are economical and safe, compared to the related-art methods. Therefore, the preparation method can be effectively applied to prepare a difluorinated alcohol used in various applications for raw materials such as functional medicines, agricultural chemicals, polymerizable compounds, etc.

Abstract: A mobile terminal and a method for controlling the same are disclosed. The mobile terminal includes: a case having a plurality of faces; a sensing unit provided inside the case; a display unit seamlessly provided to at least two of the plurality of faces; and a controller configured to display a first display unit and a second display unit of the display unit such that the first display unit and the second display unit respectively correspond to a first face and a second face of an entity and to change an image displayed on at least one of the first and second display units to correspond to a position change of the case upon sensing of the position change of the case through the sensing unit, the first and second display units having different directions.

Abstract: The present invention discloses a mobile terminal capable of controlling a main display area via an auxiliary display area implemented by a flexible display. In particular, according to the present invention, the mobile terminal includes a sensing unit configured to detect a movement of the mobile terminal, a display unit configured to contain a main display area exposed to the front side and an auxiliary display area exposed to the side and a controller, if the detected movement satisfies a prescribed condition, configured to control the display unit to switch to an image sharing mode, the controller, if the mobile terminal enters the image sharing mode, configured to control the display unit to output image data on the main display area and output a thumbnail list for a plurality of images on the auxiliary display area.

Abstract: The present disclosure may provide a mobile terminal including a body having a front surface, a rear surface and a lateral surface thereof, a display unit disposed on the front surface to display first screen information, a lateral touch sensing unit formed on the lateral surface adjacent to both edges of the display unit to receive a user's consecutive touch input, and a controller configured to control the display unit to display second screen information in one region on the display unit corresponding to a touch range of the consecutive touch input.

Abstract: The disclosure is related to monitoring a legacy device using at least one smart device. A gateway of an automation system may monitor an operation status of a target legacy device located in a service area of an automation system using at least one of smart devices participating in the automation system. In order to monitor, a monitoring request may be received for monitoring the target legacy device from user equipment associated with a user. At least one of monitoring smart devices may be controlled for monitoring the target legacy device. Monitoring results may be received from the at least one of monitoring smart devices. The received monitoring results may be provided to the user through the user equipment using at least one of outputting monitoring smart devices.

Abstract: A mobile terminal and a method of controlling the operation of the mobile terminal are provided. The method includes displaying a first list including one or more items on a display module provided in a main body of the mobile terminal; determining whether the main body has been rotated so as to turn the display module upside down; and if it is determined that the mobile terminal has been rotated so as to turn the display module upside down, displaying a second list, instead of the first list, on the display module. Therefore, it is possible to control various operations performed by the mobile terminal in accordance with the movement of the main body of the mobile terminal.

Abstract: Described embodiments provide managing data collected from machine 2 machine (M2M) devices. A plurality of M2M devices may be grouped based on a common interest and the same group authorization key may be assigned to M2M devices in the same device group. A data collecting terminal having a group authorization key may be allowed to collect data in M2M devices when the M2M devices have the same group authorization key.

Abstract: A mobile terminal and a method of controlling the operation of the mobile terminal are provided. The method includes operating a camera provided in a main body of the mobile terminal in a first camera mode, and displaying a screen corresponding to an operation selected during the first camera mode on a display module; and if a 360-degree rotation of the main body about a predetermined axial direction is detected, operating the camera in a second camera mode and displaying a screen corresponding to an operation selected during the second camera mode on the display module. Therefore, it is possible to easily switch the mobile terminal from one camera mode to another camera mode in accordance with the movement of the main body of the mobile terminal.