Abstract: The present disclosure relates to a temperature-sensitive nanoparticle/hydrogel complex, and more particularly, the temperature-sensitive nanoparticle/hydrogel complex for sustained-release drug release that can delay the drug release rate at the administration site, thereby maximizing the drug treatment efficacy at the local site by the interaction between the drug and the nanoparticles as well as the interaction between the drug and the hydrogel when mixing a drug-free nanoparticle/hydrogel complex and a predetermined drug.

Abstract: Disclosed is a method of preparing a knitting yarn having a water-repellent function, including providing a knitting yarn in the form of a skein or a cone, washing the provided yarn to remove impurities and oil therefrom, coating the washed yarn with a water-repellent agent by spraying a water repellent solution containing the water-repellent agent at a predetermined pressure, dehydrating and drying the coated yarn, and fixing the water-repellent agent to the yarn by applying heat to the dried yarn.

Abstract: Disclosed is a method of preparing a knitting yarn having a water-repellent function, including providing a knitting yarn in the form of a skein or a cone, washing the provided yarn to remove impurities and oil therefrom, coating the washed yarn with a water-repellent agent by spraying a water repellent solution containing the water-repellent agent at a predetermined pressure, dehydrating and drying the coated yarn, and fixing the water-repellent agent to the yarn by applying heat to the dried yarn.

Abstract: The present disclosure relates to a novel strain capable of saccharifying and fermenting biomass-derived cellulose and a recombinant strain thereof with improved biomass saccharification capability. The present disclosure also relates to a method for producing a material useful as a bioenergy source material such as ethanol, acetic acid, formic acid, etc. using the strain or the recombinant strain. The strain or the recombinant strain may be usefully used in bioenergy industry.

Abstract: The present disclosure relates to a novel strain capable of saccharifying and fermenting biomass-derived cellulose and a recombinant strain thereof with improved biomass saccharification capability. The present disclosure also relates to a method for producing a material useful as a bioenergy source material such as ethanol, acetic acid, formic acid, etc. using the strain or the recombinant strain. The strain or the recombinant strain may be usefully used in bioenergy industry.

Abstract: Provided are a method of enhancing radiation sensitivity by using miR-499b-5p and a method of treating a radiation resistant cancer including administering miR-499b-5p.

Abstract: Provided are a method of enhancing radiation sensitivity by using miR-499b-5p and a method of treating a radiation resistant cancer including administering miR-499b-5p.

Abstract: Provided is a method of providing a favorite shop management service in electronic commerce using the Internet for inducing continuous and repeated purchases rather than a one-time purchase by classifying an interest shop, a purchased shop, or an impressive shop as a favorite shop based on the repeated number of purchases or a purchase amount of selling products pre-registered by a seller, and differentially managing the classified favorite shop.

Abstract: The present disclosure provides a composition for radiation exposure diagnosis including an agent for measuring an expression level of an insulin-like growth factor-binding protein-5 (IGFBP-5) gene at an mRNA or the protein and a kit for radiation exposure diagnosis. Methods of diagnosing radiation exposure as well as methods for screening an agent for enhancing radiation sensitivity or for radiation protection are disclosed. Also provided are compositions for enhancing radiation sensitivity and/or radiation protection.

Abstract: A method for avoiding side collision of vehicles at cross roads (where two or more roads meet) by utilizing a side collision prediction algorithm. The method for avoiding side collision of vehicles includes the steps of controlling the movement of the vehicle that is compliant with the traffic light and has started moving, by either rapid acceleration or deceleration when the driver of a first vehicle is unable to promptly respond to a second vehicle approaching from the side (left to right or right to left) in violation of the traffic light signal, or in cases where a collision is unavoidable, by causing the collision to occur as far away from the occupant compartment of the first vehicle as possible to minimize any injuries of the passengers in the first vehicle.

Abstract: A method for avoiding side collision of vehicles at cross roads (where two or more roads meet) by utilizing a side collision prediction algorithm. The method for avoiding side collision of vehicles includes the steps of controlling the movement of the vehicle that is compliant with the traffic light and has started moving, by either rapid acceleration or deceleration when the driver of a first vehicle is unable to promptly respond to a second vehicle approaching from the side (left to right or right to left) in violation of the traffic light signal, or in cases where a collision is unavoidable, by causing the collision to occur as far away from the occupant compartment of the first vehicle as possible to minimize any injuries of the passengers in the first vehicle.

Abstract: Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.

Abstract: This invention provides atorvastatin strontium salt or its hydrates or polymorphs having improved water solubility, which is useful for the prevention or treatment of hyperlipidemia and hypercholesterolemia, and a pharmaceutical composition comprising same.

Abstract: Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.

Abstract: This invention provides a crystalline azithromycin L-malate monohydrate for treating various microbial infections, which has high thermostability, solubility and non-hygroscopicity, a method for preparing same, and a pharmaceutical composition containing same.

Abstract: Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.

Abstract: The present invention relates to a method for preparing clopidogrel 1,5-naphthalenedisulfonate or a hydrate thereof, which comprises reacting a clopidogrel-acid addition salt with disodium 1,5-naphthalenedisulfonate or its hydrate in water, or a mixture of water and an organic solvent. High quality clopidogrel 1,5-naphthalenedisulfonate can be prepared by the inventive method by way of using non-corrosive disodium 1,5-naphthalenedisulfonate.

Abstract: The present invention relates to a method for preparing clopidogrel 1,5-naphthalenedisulfonate or a hydrate thereof, which comprises reacting a clopidogrel-acid addition salt with disodium 1,5-naphthalenedisulfonate or its hydrate in water, or a mixture of water and an organic solvent. High quality clopidogrel 1,5-naphthalenedisulfonate can be prepared by the inventive method by way of using non-corrosive disodium 1,5-naphthalenedisulfonate.

Abstract: A crystalline clopidogrel naphthalenesulfonate or a hydrate thereof, a method for preparing same, and a pharmaceutical composition containing same are provided.

Abstract: Ticlopidine and clopidogrel having high blood platelet aggregation inhibitory and anti-thrombotic activities are simply prepared by reacting a substituted thiophene derivative with a 2-chlorobenzylamine derivative.