Abstract: Provided is a novel JAK-specific inhibitor compound and a method for preparing the same. The compound of the provided can exhibit therapeutic effects on a variety of diseases, for example, inflammatory diseases, autoimmune diseases, myeloproliferative diseases, and human cancers due to its ability to regulate signal transduction at the level of JAK kinases. In particular, due to its high selectivity for JAK1, the compound of the provided can exhibit better therapeutic effects on inflammatory diseases and autoimmune diseases at a low dose and with fewer side effects and can be expected to be effective in preventing and treating liver fibrosis.

Abstract: The present invention relates to a composition for preventing hair loss or promoting hair growth containing a milk thistle flower extract as an active ingredient. More specifically, the present invention relates to a cosmetic composition, pharmaceutical composition and food composition containing a milk thistle flower extract as an active ingredient, which are able to promote hair growth by inducing the proliferation of dermal papilla cells reduced due to senescence, and activate dermal papilla cells by inhibiting the senescence of dermal papilla cells through inhibition of the activity of senescence-associated ?-galactosidase (SA-?-Gal) and the production of senescence-associated secretory phenotypes, thereby preventing hair loss or promoting hair.

Abstract: The present disclosure relates to an isolated anti-FcRN antibody, which is an antibody binding to FcRN (stands for neonatal Fc receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmunre diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases.

Abstract: The present invention relates to a composition for an organic optoelectronic device, the composition comprising: a first host compound represented by Chemical Formula 1 below; and a second host compound represented by Chemical Formula 2 below, to an organic optoelectronic device using the composition and a display device. The details of Chemical Formulas 1 and 2 above are as defined in the specification.

Abstract: The present invention relates to a composition for an organic optoelectronic device, the composition comprising: a first host compound represented by Chemical Formula 1 below; and a second host compound represented by Chemical Formula 2 below, to an organic optoelectronic device using the composition and a display device. The details of Chemical Formulas 1 and 2 above are as defined in the specification.

Abstract: Disclosed are a compound represented by Chemical Formula 1, a composition comprising the same, an organic optoelectronic diode, and a display device. Chemical formula 1 is as defined in the specification.

Abstract: The present invention relates to a pidolate salt and malate salt of a compound represented by a formula 1 with an excellent liquid-phase stability, solid-phase stability, water solubility, precipitation stability and hygroscopicity all together as a compound for preventing and treating diseases mediated by an acid pump antagonistic activity, as well as a method for preparing the same.

Abstract: A secondary battery including an electrode assembly and a pouch configured to accommodate the electrode assembly. The pouch includes two first covers provided on both surfaces of the electrode assembly in a thickness direction and two second covers provided on both surfaces of the electrode assembly in a full-width direction. The edge surfaces of the first covers and the second covers are sealed by a first sealing part, and the end surfaces of the first covers and the second covers are sealed by a second sealing part. The two second covers are in close contact with both the surfaces of the electrode assembly in the full-width direction.

Abstract: Disclosed are an ink composition, a layer manufactured using the ink composition, an electrophoresis device including the layer, and a display device, the ink composition including (A) a semiconductor nanorod including: a functional group represented by Chemical Formula 1; and (B) a solvent. In Chemical Formula 1, each substituent is as defined in the specification.

Abstract: Disclosed are an ink composition, a layer manufactured using the ink composition, and an electrophoresis device and a display device including the same. The ink composition includes (A) a semiconductor nanorod; and (B) a mixed solvent including a first solvent, a second solvent, and a third solvent, wherein the first solvent has a viscosity of less than or equal to 70 cps at 25° C. and includes a compound having a dielectric constant of greater than or equal to 5, the second solvent includes a compound having a viscosity of greater than or equal to 80 cps at 25° C. or being a solid or having a dielectric constant of greater than or equal to 5, and the third solvent includes a compound having a dielectric constant of less than 5.

Abstract: Disclosed are a method and system for managing pressure ulcers and computing device for executing the same. The computing device according to a disclosed embodiment is a computing device provided with one or more processors and a memory storing one or more programs executed by the one or more processors, the computing device including a pressure ulcer risk level evaluation module configured to acquire pressure ulcer risk factor information of a patient admitted to a hospital and calculate a pressure ulcer risk level of the corresponding patient based on the acquired pressure ulcer risk factor information, and a pressure ulcer prevention management module configured to schedule a pressure ulcer prevention activity for a patient whose pressure ulcer risk level is equal to or higher than a predetermined threshold level.

Abstract: A printed circuit board includes: a first insulating layer; a via pad including a first layer embedded in the first insulating layer and a second layer disposed on the first layer; and a first via layer disposed on the via pad, wherein the second layer has a width decreasing in a direction away from the first layer in a stacking direction of the first and second layers.

Abstract: Disclosed is a negative electrode including: a current collector; a negative electrode active material layer disposed on at least one surface of the current collector, including a silicon-based active material and a conductive material, and containing no binder polymer; and a coating layer disposed on the surface of the negative electrode active material layer and in at least a part of the inside of the pores of the negative electrode active material layer, and containing a coating layer polymer forming a chemical bond with silicon (Si) of the silicon-based active material, wherein the content of the coating layer polymer is 0.3-2 parts by weight based on 100 parts by weight of the negative electrode active material layer, and the coating layer polymer is a mixture of polyacrylic acid with polyvinyl alcohol.

Abstract: An eco-friendly biodegradable polyester resin composition includes a polyester resin that includes a diol, an aromatic dicarboxylic acid and an aliphatic dicarboxylic acid, wherein a biodegradability per aliphatic carboxylic acid is 1.7 or more, the biodegradability per aliphatic carboxylic acid being a value obtained by dividing a biodegradability after 9 weeks by a ratio of the aliphatic dicarboxylic acid to the total dicarboxylic acid, and the biodegradability after 9 weeks being 85% or more.

Abstract: Embodiments provide an ink composition, a layer manufactured using the ink composition, and an electrophoresis apparatus and a display device including the same. The ink composition includes a semiconductor nanorod including at least one functional group each independently represented by one of Chemical Formula 1-1 to Chemical Formula 1-3, and a solvent.

Abstract: Disclosed are an ink composition, a layer manufactured using the ink composition, an electrophoresis apparatus including the layer, and a display device, the ink composition including (A) a semiconductor nanorod, and (B) a solvent including a compound having a set or specific structure, wherein the solvent has an electrical conductivity of less than 2.0 ?S/m at 25° C.

Abstract: An eco-friendly biodegradable polyester resin composition, including: a polyester resin including a diol, an aromatic dicarboxylic acid and an aliphatic dicarboxylic acid, wherein a soft segment ratio of the polyester resin is 0.21 to 0.29, and wherein the soft segment ratio is a ratio of a diol, bonded between the aliphatic dicarboxylic acid and the aliphatic dicarboxylic acid, among the diols.

Abstract: The present invention relates to a compound for an organic photoelectronic element, to a composition for an organic photoelectronic element, the composition including the compound for an organic photoelectronic element, to an organic photoelectronic element employing the same, and to a display device.

Abstract: Disclosed are an organic optoelectronic device includes an anode and a cathode facing each other and an organic layer disposed between the anode and the cathode, wherein the organic layer includes at least one of a hole injection layer, a hole transport layer, a light emitting layer, and an electron transport layer, and the light emitting layer includes a first host, a second host, and a phosphorescent dopant represented by Chemical Formula 4, and a display device including the same.