Abstract: A device for intravascular intervention can comprise an intervention element and an elongate manipulation member. The elongate member can comprise a hooked portion extending about a proximal portion of the intervention element. The hooked portion can have a first segment, a second segment, and a bend between the first and second segments, with the first segment and the second segment located on different sides of the intervention element. At least one of the first segment or the second segment can have an extending portion that extends into a region that is (i) between a top side and a bottom side of the intervention element, and (ii) distal to a proximal part of the intervention element. The extending portion and the proximal part can be aligned such that a line extending in a proximal-distal direction intersects the extending portion and the proximal part.

Abstract: Disclosed are methods for detecting, diagnosing or monitoring a renal cancer in a subject. The methods include detecting quantity of one or more polypeptides or fragments thereof comprised by body fluid such as urine, wherein the one or more polypeptides or fragments thereof, can be present at elevated levels in a subject with, a kidney cancer, as compared to a subject without a kidney cancer. Non-limiting examples of such polypeptides include aquaporin-1, adipose differentiation-related protein, and paired box protein-2. Antibody probes can be used to detect or quantify the polypeptides. In some embodiments, mass spectroscopy can be used to detect or quantify the polypeptides, or to identify a polypeptide in a body fluid sample from a subject with a kidney cancer.

Abstract: The present disclosure relates to a medication adherence administration and monitoring system. An apparatus for managing medication adherence by a patient is provided, the apparatus comprising: a dispensing device configured for communication with a medication administration system, the dispensing device designed for dispensing medication stored within the dispensing device to the patient; a control system for controlling the dispensing device based, at least in part, on command instructions provided by the medication administration system, and issuing commands to dispense medication based on the satisfaction of one or more pre-determined conditions provided by the medication administration system; and an alert system configured for alerting the patient when medication should be dispensed and configured to receive an indication from the patient verifying the consumption of medication, the alert system communicating to the control system that the medication has been dispensed and consumed.

Abstract: A pre-knotted necktie system is described. Embodiments of the pre-knotted necktie system can include a body, a pre-knotted necktie coupled to the body, and an attachment mechanism. The attachment mechanism can be implemented to secure the pre-knotted necktie and body to a neck of a wearer. Typically, the attachment mechanism can be a strap having releasably coupled ends. The strap can be passed through one or more apertures of the body, thus enabling the body to be secured to a neck of the wearer.

Abstract: A device for intravascular intervention can comprise an intervention element, an elongate manipulation member, and a joining element. The elongate member can comprise a hooked portion extending about a proximal portion of the intervention element. The joining element can substantially permanently attach the hooked portion to the intervention element.

Abstract: Disclosed are methods for detecting, diagnosing or monitoring a renal cancer in a subject. The methods include detecting quantity of one or more polypeptides or fragments thereof comprised by body fluid such as urine, wherein the one or more polypeptides or fragments thereof, can be present at elevated levels in a subject with, a kidney cancer, as compared to a subject without a kidney cancer. Non-limiting examples of such polypeptides include aquaporin-1, adipose differentiation-related protein, and paired box protein-2. Antibody probes can be used to detect or quantify the polypeptides. In some embodiments, mass spectroscopy can be used to detect or quantify the polypeptides, or to identify a polypeptide in a body fluid sample from a subject with a kidney cancer.

Abstract: A loop-powered transmitter includes a data isolation transformer including primary and secondary windings and an analog-to-digital converter (ADC) to convert a sensor signal to a digital value. The transmitter also includes a first microcontroller coupled between a multi-signal interface of the ADC and only one tap of the primary winding of the data isolation transformer, and a second microcontroller coupled to the secondary winding of the data isolation transformer. The first microcontroller is configured to receive the digital value from the ADC over the multi-signal interface and to provide data indicative of the digital value via a single output data line through the tap of the primary winding of the data isolation transformer to the second microcontroller. Unipolar voltage converters may also be included in the transmitter along with a current limiting resistor for the data isolation transformer to reduce the risk of saturating the data isolation transformer.

Abstract: A new cultivar of Daphne plant named ‘Sweet Amethyst’ that is characterized by a large number of light purple flowers that have a strong jasmine scent, a long flowering season and elliptic to obovate shaped green leaves.

Abstract: Disclosed are methods for detecting, diagnosing or monitoring a renal cancer in a subject. The methods include detecting quantity of one or more polypeptides or fragments thereof comprised by body fluid such as urine, wherein the one or more polypeptides or fragments thereof, can be present at elevated levels in a subject with a kidney cancer, as compared to a subject without a kidney cancer. Non-limiting examples of such polypeptides include aquaporin-1, adipose differentiation-related protein and paired box protein-2. Antibody probes can be used to detect or quantify the polypeptides. In some embodiments, mass spectroscopy can be used to detect or quantify the polypeptides, or to identify a polypeptide in a body fluid sample from a subject with a kidney cancer.

Abstract: A vascular remodeling device is provided. The device has an anchor portion, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. The device also includes a distal portion sized for deployment in a blood vessel. The distal portion is radially expandable from a collapsed state to an expanded state and has a distal face that is sufficiently occlusive in the distal-to-proximal direction to perform a therapeutic blocking function in an aneurysm neck. The device also has an intermediate portion that interconnects a distal end of the anchor portion and a proximal end of the distal portion. In some embodiments, the anchor portion and/or distal portion has a plurality of interconnected struts.

Abstract: A stent delivery system can include a core member, first and second restraints, and a stent engagement component. The core member can have a distal segment. The first and second restraints can be coupled to the core member distal segment and axially spaced apart from each other to provide an axial gap. The first and second restraints can each have an outer profile that tapers radially inwardly in directions away from the gap. The stent engagement component can be at least partially disposed in the axial gap between the first and second restraints such that the component is slidably and rotatably coupled to the core member distal segment.

Abstract: A vascular remodeling device has a plurality of sections, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. Each section has a plurality of interconnected struts that define a waist, a proximal face, and a distal face. Each face comprises (i) a plurality of distal strut portions extending proximally from a distal side of the face, (ii) a plurality of proximal strut portions extending distally from a proximal side of the face, and (iii) a plurality of sub-struts, wherein, from each proximal strut portion, two of the sub-struts each extend to a different one of the distal strut portions.

Abstract: The medical device can comprise a manipulation member, a mechanical thrombectomy apparatus attached to a distal end of the manipulation member, and flow-restricting apparatus attached to the manipulation member to a location proximal to the mechanical thrombectomy apparatus. A method, for retrieving thrombus from a blood vessel, can comprise advancing a single elongate delivery member carrying a mechanical thrombectomy apparatus and a flow-restricting apparatus through a catheter to the blood vessel, expanding the thrombectomy apparatus and capturing the thrombus with the thrombectomy device, expanding the flow-restricting apparatus to at least partially occlude blood flow toward the thrombus, retracting at least a portion of the thrombectomy apparatus into the flow-restricting apparatus, and retracting the flow-restricting apparatus and the thrombectomy apparatus into the retrieval catheter.

Abstract: A method for preparing an antimicrobial alcoholic foam composition by combining two or more pre-mix compositions. A first pre-mix composition is primarily alcoholic comprises an alcohol, an acidic component, and a waxy component. A second pre-mix composition is primarily aqueous comprises water and a carbonate. An antimicrobial alcoholic foam composition that does not require added air or aerosol propellant is also provided.

Abstract: A stent delivery system can include a core member, first and second restraints, and a stent engagement component. The core member can have a distal segment. The first and second restraints can be coupled to the core member distal segment and axially spaced apart from each other to provide an axial gap. The first and second restraints can each have an outer profile that tapers radially inwardly in directions away from the gap. The stent engagement component can be at least partially disposed in the axial gap between the first and second restraints such that the component is slidably and rotatably coupled to the core member distal segment.

Abstract: A vascular remodeling device has a plurality of sections, sized for deployment in a blood vessel, that is radially expandable from a collapsed state to an expanded state. Each section has a plurality of interconnected struts that define a waist, a proximal face, and a distal face. Each face comprises (i) a plurality of distal strut portions extending proximally from a distal side of the face, (ii) a plurality of proximal strut portions extending distally from a proximal side of the face, and (iii) a plurality of sub-struts, wherein, from each proximal strut portion, two of the sub-struts each extend to a different one of the distal strut portions.

Abstract: A new cultivar of Daphne plant named ‘Sweet Amethyst’ that is characterized by a large number of light purple flowers that have a strong jasmine scent, a long flowering season and elliptic to obovate shaped green leaves.