Patents by Inventor Evelyn Auyeung

Evelyn Auyeung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210002393
    Abstract: A solution polymerization process for producing ethylene-based polymer includes introducing ethylene monomer, hydrocarbon solvent, and Ziegler-Natta catalyst into an entrance of a solution polymerization reactor. An ethylene-based polymer is produced by solution polymerizing the ethylene monomer in hydrocarbon solvent. Subsequently, a catalyst deactivator is introduced into the exit of the solution polymerization reactor, thereby producing hydrochloric acid byproduct. The catalyst deactivator includes long chain carboxylate and at least one cation selected from Groups 1, 2, and 12 of the IUPAC periodic table, with the exception of calcium. The catalyst deactivator reduces the effectiveness of the Ziegler-Natta catalyst and neutralizes the hydrochloric acid by forming a chloride salt other than calcium chloride.
    Type: Application
    Filed: March 25, 2019
    Publication date: January 7, 2021
    Applicant: Dow Global Technologies LLC
    Inventors: Evelyn Auyeung, Sean W. Ewart, Daniela Ferrari, Thomas Davidian, Rony Vanspeybroeck
  • Publication number: 20180344873
    Abstract: Spherical nucleic acids (SNAs), consisting of densely packed, highly oriented polynucleotide strands attached to the surface of nanoparticles, are able to overcome the typical challenges of nucleic acid delivery. The present disclosure demonstrates that G-rich SNAs exhibit several-fold higher uptake into cells relative to SNAs rich in other nucleotides. This disclosure provides an effective strategy to maximize the intracellular delivery of SNAs, which is applicable to other nanoparticle systems, thus establishing an important design consideration for nanoparticle-based intracellular delivery of therapeutics.
    Type: Application
    Filed: November 20, 2015
    Publication date: December 6, 2018
    Inventors: Chad A. Mirkin, Chung Hang J. Choi, Sunguna P. Narayan, Liangliang Hao, Evelyn Auyeung
  • Publication number: 20160159834
    Abstract: The present disclosure is directed to compositions comprising alkyne oligonucleotides, nanoconjugates prepared from the same, and methods of their use.
    Type: Application
    Filed: April 22, 2014
    Publication date: June 9, 2016
    Inventors: Andrew Lee, Chad A. Mirkin, Colin Michael Calabrese, Natalia Chernyak, Evelyn Auyeung