Patents by Inventor Ewald Rieger

Ewald Rieger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11221324
    Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: January 11, 2022
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Heino Eikmeier, Hans-Peter Haar, Joachim Hoenes, Carina Horn, Ewald Rieger
  • Patent number: 10422765
    Abstract: Electrode systems are disclosed for measuring the concentration of an analyte under in vivo conditions, where the systems includes an electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. Methods of making and using the system also are disclosed.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: September 24, 2019
    Assignee: ROCHE DIABETES CARE, INC.
    Inventors: Arnulf Staib, Marcel Thiele, Karl-Heinz Koelker, Ewald Rieger
  • Patent number: 10390743
    Abstract: Electrode systems are disclosed for measuring the concentration of an analyte under in-vivo conditions, where such systems include a counter electrode having an electrical conductor, a working electrode having an electrical conductor on which an enzyme layer containing immobilized enzyme molecules for catalytic conversion of the analyte is arranged, and a diffusion barrier that slows the diffusion of the analyte from body fluid surrounding the electrode system to enzyme molecules. The enzyme layer is in the form of multiple fields that are arranged on the conductor of the working electrode at a distance from each other.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: August 27, 2019
    Assignee: ROCHE DIABETES CARE, INC.
    Inventors: Ewald Rieger, Reinhold Mischler, Ortrud Quarder, Arnulf Staib, Ulrike Kamecke, Ralph Gillen
  • Publication number: 20190254574
    Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
    Type: Application
    Filed: May 3, 2019
    Publication date: August 22, 2019
    Inventors: Harvey Buck, Georgeta Lica, Karl-Heinz Koelker, Ewald Rieger
  • Patent number: 10349878
    Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: July 16, 2019
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Harvey Buck, Georgeta Lica, Karl-Heinz Koelker, Ewald Rieger
  • Publication number: 20190049427
    Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Inventors: Heino Eikmeier, Hans-Peter Haar, Joachim Hoenes, Carina Horn, Ewald Rieger
  • Patent number: 10150114
    Abstract: Methods are disclosed for manufacture of test elements for detecting at least one analyte in a body fluid, where the test elements include a housing having at least one base element and at least one cover element. The methods include providing the base element, and mounting the cover element to the base element with an adhesive, wherein the adhesive contacts at least one test field of the cover element such that the adhesive is interposed between the test field and the base element and at least partially covers the test field. The test elements also include at least one fluid channel formed within the housing, where the the fluid channel includes a capillary region and a measurement region. The capillary region and the measurement region have differing aspect ratios. The at least one test field has at least one test chemical, where the test chemical is adapted to change at least one optically measurable property in the presence of the analyte.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: December 11, 2018
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Bernd Hiller, Rudolf Pachl, Daniela Pfiffi, Ewald Rieger, Christa Sternberger
  • Patent number: 10132792
    Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: November 20, 2018
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Heino Eikmeier, Hans-Peter Haar, Joachim Hoenes, Carina Horn, Ewald Rieger
  • Publication number: 20180297030
    Abstract: Methods are disclosed for manufacture of test elements for detecting at least one analyte in a body fluid, where the test elements include a housing having at least one base element and at least one cover element. The methods include providing the base element, and mounting the cover element to the base element with an adhesive, wherein the adhesive contacts at least one test field of the cover element such that the adhesive is interposed between the test field and the base element and at least partially covers the test field. The test elements also include at least one fluid channel formed within the housing, where the the fluid channel includes a capillary region and a measurement region. The capillary region and the measurement region have differing aspect ratios. The at least one test field has at least one test chemical, where the test chemical is adapted to change at least one optically measurable property in the presence of the analyte.
    Type: Application
    Filed: June 21, 2018
    Publication date: October 18, 2018
    Inventors: Bernd Hiller, Rudolf Pachl, Daniela Pfiffi, Ewald Rieger, Christa Sternberger
  • Patent number: 10029252
    Abstract: Test elements are disclosed for detecting at least one analyte in a body fluid, where the test elements include a housing having at least one base element and at least one cover element. The test elements also include at least one fluid channel formed within the housing, where the fluid channel includes a capillary region and a measurement region. The capillary region and the measurement region have differing aspect ratios. The cover element includes at least one test field having at least one test chemical, where the test chemical is adapted to change at least one optically measurable property in the presence of the analyte. In addition, the cover element is mounted to the base element via at least one adhesive that contacts the test field.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: July 24, 2018
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Bernd Hiller, Rudolf Pachl, Daniela Pfiffi, Ewald Rieger, Christa Sternberger
  • Publication number: 20170367628
    Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Inventors: Harvey Buck, Georgeta Lica, Karl-Heinz Koelker, Ewald Rieger
  • Patent number: 9757060
    Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: September 12, 2017
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Harvey Buck, Georgeta Lica, Karl-Heinz Koelker, Ewald Rieger
  • Publication number: 20160296151
    Abstract: Electrode systems are disclosed for measuring the concentration of an analyte under in-vivo conditions, where such systems include a counter electrode having an electrical conductor, a working electrode having an electrical conductor on which an enzyme layer containing immobilized enzyme molecules for catalytic conversion of the analyte is arranged, and a diffusion barrier that slows the diffusion of the analyte from body fluid surrounding the electrode system to enzyme molecules. The enzyme layer is in the form of multiple fields that are arranged on the conductor of the working electrode at a distance from each other.
    Type: Application
    Filed: June 17, 2016
    Publication date: October 13, 2016
    Inventors: Ewald Rieger, Reinhold Mischler, Ortrud Quarder, Arnulf Staib, Ulrike Kamacke, Ralph Dillen
  • Patent number: 9394563
    Abstract: An electrode system for measuring the concentration of an analyte under in-vivo conditions comprises a counter-electrode having an electrical conductor, a working electrode having an electrical conductor on which an enzyme layer containing immobilized enzyme molecules for catalytic conversion of the analyte is arranged, and a diffusion barrier that slows the diffusion of the analyte from body fluid surrounding the electrode system to enzyme molecules. The enzyme layer is in the form of multiple fields that are arranged on the conductor of the working electrode at a distance from each other.
    Type: Grant
    Filed: March 8, 2011
    Date of Patent: July 19, 2016
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Ortrud Quarder, Arnulf Staib, Reinhold Mischler, Ewald Rieger, Ralph Gillen, Ulrike Kamecke
  • Publication number: 20160082434
    Abstract: Test elements are disclosed for detecting at least one analyte in a body fluid, where the test elements include a housing having at least one base element and at least one cover element. The test elements also include at least one fluid channel formed within the housing, where the fluid channel includes a capillary region and a measurement region. The capillary region and the measurement region have differing aspect ratios. The cover element includes at least one test field having at least one test chemical, where the test chemical is adapted to change at least one optically measurable property in the presence of the analyte. In addition, the cover element is mounted to the base element via at least one adhesive that contacts the test field.
    Type: Application
    Filed: December 7, 2015
    Publication date: March 24, 2016
    Inventors: Bernd Hiller, Rudolf Pachl, Daniela Pfiffi, Ewald Rieger, Christa Sternberger
  • Publication number: 20150320345
    Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
    Type: Application
    Filed: July 20, 2015
    Publication date: November 12, 2015
    Inventors: Harvey Buck, Georgeta Lica, Karl-Heinz Koelker, Ewald Rieger
  • Patent number: 9084570
    Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: July 21, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Harvey Buck, Georgeta Lica, Karl-Heinz Koelker, Ewald Rieger
  • Publication number: 20150005605
    Abstract: An electrode system is disclosed for measuring a concentration or presence of an analyte under in-vivo conditions, where the electrode system includes at least one electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. The diffusion barrier includes a hydrophilic polyurethane or a block copolymer having at least one hydrophilic block and at least one hydrophobic block. The electrode system also can include a spacer membrane that includes a hydrophilic copolymer of acrylic and/or methacrylic monomers.
    Type: Application
    Filed: September 15, 2014
    Publication date: January 1, 2015
    Inventors: Arnulf Staib, Marcel Thiele, Karl-Heinz Koelker, Ewald Rieger
  • Publication number: 20140238118
    Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.
    Type: Application
    Filed: September 27, 2013
    Publication date: August 28, 2014
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Heino Eikmeier, Hans-Peter Haar, Joachim Hoenes, Carina Horn, Ewald Rieger
  • Publication number: 20140041443
    Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.
    Type: Application
    Filed: September 27, 2013
    Publication date: February 13, 2014
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Heino Eikmeier, Hans-Peter Haar, Joachim Hoenes, Carina Horn, Ewald Rieger