Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.

Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.

Abstract: Electrode systems are disclosed for measuring the concentration of an analyte under in vivo conditions, where the systems includes an electrode with immobilized enzyme molecules and an improved diffusion barrier that controls diffusion of the analyte from body fluid surrounding the electrode system to the enzyme molecules. Methods of making and using the system also are disclosed.

Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.

Abstract: An electrode system for measuring the concentration of an analyte under in-vivo conditions comprises a counter-electrode having an electrical conductor, a working electrode having an electrical conductor on which an enzyme layer containing immobilized enzyme molecules for catalytic conversion of the analyte is arranged, and a diffusion barrier that slows the diffusion of the analyte from body fluid surrounding the electrode system to enzyme molecules. The enzyme layer is in the form of multiple fields that are arranged on the conductor of the working electrode at a distance from each other.

Abstract: System and method for the determination of a coagulation parameter comprising a disposable test element and an instrument for evaluation thereof. The coagulation time is determined at a non-standard temperature different from a standard temperature for the respective coagulation parameter, the non-standard temperature being measured by a temperature measurement device of the instrument, the instrument has a non-volatile memory containing data which define a mathematical relationship of coagulation time versus temperature which relationship is independent of the individual patient whose blood is examined, and the coagulation parameter for the standard temperature is calculated from the coagulation time measured at the non-standard temperature, using the mathematical relationship.

Abstract: New N-heteroarylalkylenediamine ##STR1## wherein R.sub.1 and R.sub.2 each independently is hydrogen, an alkyl radical containing up to 6 carbon atoms, or a benzyl radical,X is an alkylene radical containing 2 to 6 carbon atoms,A is a mono- or bicyclic heteroaromatic radical, which can be partly hydrogenated, with the proviso that it contains 2 or 3 adjacent ring heteroatoms, whereby the bound ring heteroatoms can be an oxygen atom and a nitrogen atom or 2 or 3 nitrogen atoms, andR.sub.3, R.sub.4, R.sub.5, R.sub.6 and R.sub.7 each independently is hydrogen, or an alkyl radical containing up to 6 carbon atoms, which can be substituted by hydroxyl, carbamyl, nitrile or carboxyl, an alkenyl radical containing 2 to 6 carbon atoms, a phenyl or carbamyl radical or one of the divalent substituents oxygen or sulphur,or a salt thereof. The compounds are intermediates in the synthesis of cardioactive compounds.