Abstract: In variants, the method for change analysis can include detecting a rare change in a geographic region by comparing a first and second representation, extracted from a first and second geographic region measurement sampled at a first and second time, respectively, using a common-change-agnostic model.

Abstract: A sanitary device has a programmable electronic control unit that acts on a metering and mixer valve unit. The electronic control unit has a program memory suitable for the retrievable storage of multiple different water dispensing programs and a central data processing unit that acts on at least one actuator that actuates the metering and mixer valve unit. A user interface has a display that has a central display region and a peripheral display region annularly surrounding the central display region, a rotatable setting ring around the display and at least three buttons around the setting ring. The buttons of the user interface comprise a program selection button, an output button and a temperature button. Actuating a button results in the present setting value of the button function in question being displayed in the central display region of the display.

Abstract: A sanitary room of a building has an access point for persons and a sanitary station, which has a sanitary apparatus having a metering and mixing valve unit, a lighting apparatus, and a sound apparatus. A programmable electronic controller influences the metering and mixing valve unit, the lighting apparatus, and the sound apparatus. The electronic controller has a memory for storing water discharge programs, a memory for storing lighting programs, a memory for storing sound programs, and a data-processing unit, which operates an actuator of the metering and mixing valve unit, an illuminant controller, and a sound generator. The sanitary station includes a device user interface associated with the sanitary apparatus which allows one of the water discharge programs to be selected and manually modified. Adjacent the access point, a room user interface is provided, which allows lighting programs and sound programs to be selected and manually modified.

Abstract: The present invention relates to a modular multivalent antigen-binding protein complex, use of the antigen-binding protein complex in medicine and use of the antigen-binding protein complex in the prophylaxis, treatment or diagnosis of a disorder or disease.

Abstract: The present invention provides a protein complex comprising heterodimerizing regions HRI and HRII, each comprised of antiparallel ?-strands and intervening regions wherein HRI and HRII are each interspersed fusion proteins of two human constant regions of an immunoglobulin or immunoglobulin-like proteins. The present invention also provides nucleic acid molecules comprising a sequence encoding said protein complexes and vectors comprising the nucleic acid. The present invention also provides the protein complex, the nucleic acid and the vector for use as a medicament. The present invention further provides a method of determining the amino acid sequence of HRI and/or of the amino acid sequence of HRII. The present invention also provides a method of producing amino acid chains of HRI and/or amino acid chains of HRII. The present invention further provides the protein complex for use in the N prophylaxis, treatment or diagnosis of a disorder or a disease.

Abstract: The present invention relates to a modular multivalent antigen-binding protein complex, use of the antigen-binding protein complex in medicine and use of the antigen-binding protein complex in the prophylaxis, treatment or diagnosis of a disorder or disease.

Abstract: In variants, the method for change analysis can include detecting a rare change in a geographic region by comparing a first and second representation, extracted from a first and second geographic region measurement sampled at a first and second time, respectively, using a common-change-agnostic model.

Abstract: In variants, the method for change analysis can include detecting a rare change in a geographic region by comparing a first and second representation, extracted from a first and second geographic region measurement sampled at a first and second time, respectively, using a common-change-agnostic model.

Abstract: A decay station includes a housing comprising a radiation shielding. The housing delimits a decay conduit intended for containing the irradiation targets in the predetermined linear order. The decay conduit includes a decay conduit inlet, intended to be connected to the structure of the core of the nuclear reactor for receiving the irradiation targets therefrom; and a decay conduit outlet, intended to be connected to an irradiation target discharge system for discharging the irradiation targets from the decay station. The decay station further includes an inlet distributor, located at the decay conduit inlet, and configured for releasing only a predetermined amount of irradiation targets at a time from the decay station towards the structure of the core of the nuclear reactor. The inlet distributor is configured for releasing the irradiation targets closest to the decay conduit inlet, while retaining the remaining irradiation targets in the decay conduit.

Abstract: In variants, the method for change analysis can include detecting a rare change in a geographic region by comparing a first and second representation, extracted from a first and second geographic region measurement sampled at a first and second time, respectively, using a common-change-agnostic model.

Abstract: The method for determining property feature segmentation includes: receiving a region image for a region; determining parcel data for the region; determining a final segmentation output based on the region image and parcel data using a trained segmentation module; optionally generating training data; and training a segmentation module using the training data S500.

Abstract: A radionuclide generation system including a tube system configured to permit insertion and removal of irradiation targets into an instrumentation finger of a nuclear reactor, and an irradiation target drive system configured to insert the irradiation targets into the instrumentation finger and to remove the irradiation targets from the instrumentation finger. The radionuclide generation system further includes an instrumentation and control unit which is linked to an online core monitoring system and being configured to calculate optimal irradiation locations for the irradiation targets based on the actual state of the reactor as provided by the online core monitoring system.

Abstract: The method for determining property feature segmentation includes: receiving a region image for a region; determining parcel data for the region; determining a final segmentation output based on the region image and parcel data using a trained segmentation module; optionally generating training data; and training a segmentation module using the training data S500.

Abstract: The method for determining property feature segmentation includes: receiving a region image for a region; determining parcel data for the region; determining a final segmentation output based on the region image and parcel data using a trained segmentation module; optionally generating training data; and training a segmentation module using the training data S500.

Abstract: The method for determining property feature segmentation includes: receiving a region image for a region; determining parcel data for the region; determining a final segmentation output based on the region image and parcel data using a trained segmentation module; optionally generating training data; and training a segmentation module using the training data S500.

Abstract: The present invention relates to a modular multivalent antigen-binding protein complex, use of the antigen-binding protein complex in medicine and use of the antigen-binding protein complex in the prophylaxis, treatment or diagnosis of a disorder or disease.

Abstract: A method for harvesting activated irradiation targets from an instrumentation tube system of a nuclear reactor comprises: Coupling the instrumentation tube system to a discharge tube having an apex, exit port and lock element between the apex and exit port; Passing the activated irradiation targets from the instrumentation tube system into the discharge tube and blocking movement of said targets out of the discharge tube using the lock element; Separating a predefined quantity of the targets from another quantity of targets in the discharge tube by passing the predefined quantity of targets over the apex, retaining the remainder in the discharge tube by means of the apex; Coupling the exit port to a storage container and releasing the lock element to pass via gravity the predefined quantity of targets into the storage container. Systems for generating radionuclides and harvesting activated irradiation targets adapted to the above method are also provided.

Abstract: A method of producing radionuclides from irradiation targets in a nuclear reactor uses at least one instrumentation tube system of a commercial nuclear reactor. Irradiation targets and dummy targets are inserted into an instrumentation finger and the irradiation targets are activated by exposing them to neutron flux in the nuclear reactor core to form a radionuclide. The dummy targets hold the irradiation targets at a predetermined axial position in the reactor core corresponding to a pre-calculated neutron flux density sufficient for converting the irradiation targets to the radionuclide. Separating the dummy targets from the activated irradiation targets includes exposure to a magnetic field to retain either the dummy targets or the activated irradiation targets in the instrumentation tube system and release the other one of the activated irradiation target or the dummy target from the instrumentation tube system. An apparatus adapted to the above method is also provided.

Abstract: The invention provides for an inhibitor of the huTNFRI receptor which is a human or humanized antibody construct that monovalently recognizes huTNFRI through an antigen-binding moiety, which is characterized by specific CDR sequences, a pharmaceutical preparation thereof, method of producing the inhibitor and the medical use of the inhibitor.

Abstract: The present invention provides a protein complex comprising heterodimerizing regions HRI and HRII, each comprised of antiparallel ?-strands and intervening regions wherein HRI and HRII are each interspersed fusion proteins of two human constant regions of an immunoglobulin or immunoglobulin-like proteins. The present invention also provides nucleic acid molecules comprising a sequence encoding said protein complexes and vectors comprising the nucleic acid. The present invention also provides the protein complex, the nucleic acid and the vector for use as a medicament. The present invention further provides a method of determining the amino acid sequence of HRI and/or of the amino acid sequence of HRII. The present invention also provides a method of producing amino acid chains of HRI and/or amino acid chains of HRII. The present invention further provides the protein complex for use in the N prophylaxis, treatment or diagnosis of a disorder or a disease.