Abstract: The present invention provides compositions and methods for transforming primary mammalian cells using an oncogenic form of ALK wherein the transformed cells display features of that of a corresponding tumor cell isolated from a cancer subject. The invention also provides a method for immortalizing normal CD4+ T lymphocytes with a lymphoma-characteristic form of ALK such as NPM-ALK.

Abstract: A control circuit of a flyback power converter according to the present invention comprises a low-side transistor, an active-clamper, a high-side drive circuit, and a controller. The low-side transistor is coupled to switch a transformer. The active-clamper is coupled in parallel with the transformer. The high-side drive circuit is coupled to drive the active-clamper. The controller generates a switching signal and an active-clamp signal. The switching signal is coupled to drive the low-side transistor. The switching signal is generated in accordance with a feedback signal for regulating an output of the flyback power converter. The active-clamp signal is coupled to control the high-side drive circuit and the active-clamper. The active-clamp signal is generated in response to a demagnetizing time of the transformer. The pulse number of the active-clamp signal is less than the pulse number of the switching signal in a light load condition.

Abstract: The present invention relates to a rapid and accurate polymer-based electrochemical point-of-care (POC) single platform assay for a multi-biomarker detection from whole blood to monitor renal function, including the identification of allograft dysfunction.

Abstract: A power conversion system of a multi-phase generator used to provide a power factor correction for a multi-phase generator. The power conversion system of the multi-phase generator includes a multi-phase power conversion unit and a control unit. The multi-phase power conversion unit receives a plurality of generator voltages and a plurality of generator currents generated from the multi-phase generator, and converts the generator voltages into a DC voltage and a DC current. The control unit controls the generator currents to linearly follow the generator voltages, therefore the power factor correction for the multi-phase generator is achieved.

Abstract: Disclosed are a method and device for valuating quality of a video in a time domain on a terminal side. The method comprises that: a significant movement area proportion of each video frame is calculated, video frames are divided into absolute regular frames and suspected distorted frames according to the significant movement area proportion of each video frame; a frozen frame detection, a scenario-conversion frame detection, a jitter frame detection, and a ghosting frame detection are performed on the suspected distorted frames; the video is split into scenarios according to the result of the scenario-conversion frame detection, scenario information weight of each scenario is calculated, and the quality of the video in time domain on the terminal side is determined. The disclosure increases the closeness of the evaluation result to subjective perception, expands an evaluation system of time domain distortions of the video, and reduces the probability of misjudgments.

Abstract: Methods and materials for the detection of melamine in test samples such as foodstuffs are described. Embodiments of the invention comprise combining a test sample suspected of containing melamine with a particle that produces a colorimetric and/or turbidimetric signal that is dependent upon the concentration of melamine in the test sample. In certain embodiments of the invention, the particles and test sample are combined together with a chemical compound selected to induce the aggregation melamine in a manner that amplifies the colorimetric and/or turbidimetric signal of the assay. In some embodiments of the invention, the aggregation inducing agent is not physically coupled to the particles used in the assays. In other embodiments of the invention, the aggregation inducing agent is physically coupled to the particles used in these assays.

Abstract: A controlling device for indoor apparatus includes a detection module, a human machine interface (HMI) and a wireless transmission module. The controlling device accepts supervisor's setting for an indoor electronic apparatus via the HMI, detects the environment around the controlling device for generating a plurality of detection value via the detective module, and receives another detection value from a plurality of slave detection devices in same controlling system. The controlling device generates a control command based on setting parameter of the supervisor and the plurality of detection value, and transmits the generated control command to the indoor electronic apparatus via the wireless transmission module. The indoor electronic apparatus works based on the received control command, so the environment around the controlling system can satisfy supervisor's demand.

Abstract: The present invention provides a generator brake system for providing a brake control of a generator. The generator brake system includes a power conversion unit, a sensing unit, and a control unit. The power conversion unit receives an output voltage and an output current, generated from the generator, and the power conversion unit has at least one switch unit. The sensing unit receives the output voltage and the output current to generate a voltage signal and a current signal. The control unit receives the voltage signal and the current signal. When receiving a braking signal, the control unit generates at least one control signal for correspondingly turning on the at least one switch unit, thus braking the generator in a short circuit manner.

Abstract: The present invention provides methods of making polymer-based biosensors and the biosensors made by said methods, wherein the biosensors comprise conducting polymers and negatively charged nanoparticles comprising a capture moiety. The present invention also provides methods of detecting analytes in a solution by contacting the solution with said polymer-based biosensors.

Abstract: A power control system provides an output power control for a generator. The power control system includes a power conversion unit, a sensing unit, a load-dumping unit, and a control unit. The power conversion unit receives and converts a current and a voltage, generated from the generator, to supply a load. The sensing unit receives the current and the voltage to produce a current signal and a voltage signal. The load-dumping unit is connected to the generator and the power conversion unit. The control units receives the current signal and the voltage signal, produces a current control signal to control the power conversion unit, and generates a voltage control signal to control the load-dumping so as to control the output power of the generator.

Abstract: A parallel-connected power conversion system of a multi-phase generator configured to provide a power factor correction for a multi-phase generator. The parallel-connected power conversion system includes a parallel-connected power conversion apparatus and a control unit. The parallel-connected power conversion apparatus has a plurality of power conversion units connected in parallel to each other. The parallel-connected power conversion apparatus receives a plurality of generator currents and a plurality of generator voltages generated from the multi-phase generator, and outputs a DC voltage. The control unit generates a plurality of control signals to correspondingly control the power conversion units so that the generator currents linearly follow the generator voltages, therefore the power factor correction of the multi-phase generator is achieved.

Abstract: A power control system for a generator includes a control unit, an input sensing unit, an output sensing unit, and a power conversion unit. The input sensing unit senses a voltage and a current, generated from the generator. The output sensing unit senses a load voltage and a load current, received by the load. The power conversion unit receives the voltage and the current, and converts the voltage and the current into the load voltage and the load current. The control unit judges and predicts the mechanical behavior of the generator to control the generator according to the received voltage, the current, the load voltage, and the load current.

Abstract: The present invention provides a generator brake system for providing a brake control of a generator. The generator brake system includes a power conversion unit, a sensing unit, and a control unit. The power conversion unit receives an output voltage and an output current, generated from the generator, and the power conversion unit has at least one switch unit. The sensing unit receives the output voltage and the output current to generate a voltage signal and a current signal. The control unit receives the voltage signal and the current signal. When receiving a braking signal, the control unit generates at least one control signal for correspondingly turning on the at least one switch unit, thus braking the generator in a short circuit manner.

Abstract: The present invention provides compositions and methods for transforming primary mammalian cells using an oncogenic form of ALK wherein the transformed cells display features of that of a corresponding tumor cell isolated from a cancer subject. The invention also provides a method for immortalizing normal CD4+ T lymphocytes with a lymphoma-characteristic form of ALK such as NPM-ALK.

Abstract: Methods and materials for the detection of melamine in test samples such as foodstuffs are described. Embodiments of the invention comprise combining a test sample suspected of containing melamine with a particle that produces a colorimetric and/or turbidimetric signal that is dependent upon the concentration of melamine in the test sample. In certain embodiments of the invention, the particles and test sample are combined together with a chemical compound selected to induce the aggregation melamine in a manner that amplifies the colorimetric and/or turbidimetric signal of the assay. In some embodiments of the invention, the aggregation inducing agent is not physically coupled to the particles used in the assays. In other embodiments of the invention, the aggregation inducing agent is physically coupled to the particles used in these assays.

Abstract: A method of layout pattern modification includes the following steps: step 1: performing an OPC process on a layout containing a plurality of square patterns to obtain a plurality of post-OPC patterns in correspondence with the plurality of square patterns; step 2: performing a manufacturing rule check on each of the plurality of post-OPC patterns to identify, from the plurality of post-OPC patterns, one or more post-OPC patterns violating the manufacturing rule; and step 3: rotating at least one of the one or more post-OPC patterns violating the manufacturing rule; and step 4: performing a manufacturing rule check on each of the rotated and non-rotated post-OPC patterns, if no post-OPC pattern violating the manufacturing rule is identified, finishing the process; otherwise, if one or more post-OPC patterns violating the manufacturing rule are identified, continuing to perform step 3 and step 4.

Abstract: The molecules harbored in exosomes play important roles in biological science. A highly desirable goal for exosome research is the rapid, simple, simultaneous tracking and quantification of exosome harbored molecules. Disclosed herein are methods and devices for inducing the release and measurement of biomolecules harbored in exosomes. The disclosed method, Electric Field Induced Release and Measurement (EFIRM) technique, uses an electrical field to simultaneously disrupt exosomes to release the contents and measure the harbored exosomal RNA/proteins. The exosome vesicle contents can be released within minutes. This provides a potential on-site method for the detection of exosome-harbored biomolecules.

Abstract: A control circuit of a power converter according to the present invention comprises a switching circuit, a sample-and-hold circuit and a current source. The switching circuit generates a switching signal in response to a feedback signal. The sample-and-hold circuit samples the feedback signal. The current source is coupled to a feedback terminal for generating a programming voltage. A programmable signal is generated in accordance with the programming voltage and the feedback signal, and the programmable signal is coupled to set a parameter.

Abstract: An optical proximity correction (OPC) method is disclosed, in which original design patterns are first grouped into a first group and a second group, wherein each pattern of the first group has a size greater than a size of any pattern of the second group. Next, a simple OPC model and a complex OPC model are individually established for the two groups using different numbers of convolution kernels. After that, the simple OPC model and the complex OPC model are combined together to generate a hybrid OPC model which is thereafter used to perform an OPC treatment on the original design patterns. This method is capable of shortening the OPC processing time and increasing the flexibility in utilizing OPC software and hardware resources.

Abstract: A method of manufacturing solar cell includes providing a semiconductor substrate. A coating layer is then formed on a plurality of sides. Subsequently, an anti-reflective layer is formed on the layer. Finally at least one first electrode and at least one second electrode are formed. The first and second electrodes respectively and electrically connect to the second conductive amorphous substrate and the semiconductor substrate. The potential induced degradation is greatly reduced.