Patents by Inventor Fatima Buevich

Fatima Buevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10933174
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a substrate having a hemostatic agent and an active pharmaceutical ingredient selectively positioned on the substrate. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: March 2, 2021
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie S. Soskin, Franklin R. Mansfield, Kai R. Worrell, Charlie Wood, Jorge Alberto Trevino Blanco
  • Publication number: 20200354514
    Abstract: A method for preparing tyrosine derived polyarylates includes combining a desaminotyrosyl-tyrosine ethyl ester, a desaminotyrosyl-tyrosine benzylester, succinic acid and a catalyst in a flask to produce a first mixture. Methylene chloride is added to the first mixture to produce a first suspension. Diisopropylcarbodiimide (DIPC) is added to the first mixture to produce a first solution. The first solution is added to a non-solvent to produce a precipitate. The precipitate is dissolved in methylene chloride to form a polymer solution. The polymer solution is blended with a slurry to produce polymer shreds. The polymer shreds are blended with a second slurry to produce a tyrosine derived polyarylate.
    Type: Application
    Filed: July 23, 2020
    Publication date: November 12, 2020
    Applicant: MEDTRONIC, INC.
    Inventors: SATISH PULAPURA, FATIMA BUEVICH, XIANGJI CHEN, SUPING LYU
  • Publication number: 20200330656
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a substrate and a hemostatic agent. The substrate includes a first piece and a second piece that is joined with the first piece. The first piece includes the hemostatic agent and the second piece includes an active pharmaceutical ingredient. Kits, systems and methods are disclosed.
    Type: Application
    Filed: July 7, 2020
    Publication date: October 22, 2020
    Applicant: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie S. Soskin, Franklin R. Mansfield, Kai R. Worrell, Charlie Wood, Jorge Alberto Trevino Blanco
  • Patent number: 10793670
    Abstract: A method for preparing tyrosine derived polyarylates includes combining a desaminotyrosyl-tyrosine ethyl ester, a desaminotyrosyl-tyrosine benzylester, succinic acid and a catalyst in a flask to produce a first mixture. Methylene chloride is added to the first mixture to produce a first suspension. Diisopropylcarbodiimide (DIPC) is added to the first mixture to produce a first solution. The first solution is added to a non-solvent to produce a precipitate. The precipitate is dissolved in methylene chloride to form a polymer solution. The polymer solution is blended with a slurry to produce polymer shreds. The polymer shreds are blended with a second slurry to produce a tyrosine derived polyarylate.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: October 6, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Xiangji Chen, Suping Lyu
  • Patent number: 10765782
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a substrate and a hemostatic agent. The substrate includes a first piece and a second piece that is joined with the first piece. The first piece includes the hemostatic agent and the second piece includes an active pharmaceutical ingredient. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: September 8, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie S. Soskin, Franklin R. Mansfield, Kai R. Worrell, Charlie Wood, Jorge Alberto Trevino Blanco
  • Patent number: 10767006
    Abstract: A method for hydrogenating tyrosine derived polyarylates includes dissolving a second polyarylate with DMF in a flask to produce a first solution. A catalyst is added to the first solution to produce a polymer solution. The polymer solution is filtered through a Celite bed to produce a filtrate. The filtrate is added to water and stirred to precipitate the polyarylate.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: September 8, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Dan Thanh Le, Xiangji Chen, Suping Lyu, Fatima Buevich
  • Patent number: 10765500
    Abstract: The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: September 8, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Patent number: 10737004
    Abstract: A medical prosthesis includes a tube having a length between a first end and a second end. The tube includes a polymer and at least one drug. The tube is configured to be manipulated to selectively increase and decrease the length of the tube. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: December 26, 2017
    Date of Patent: August 11, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie Soskin, Jonathan Sturtevant
  • Patent number: 10442757
    Abstract: A method for preparing diphenol compounds includes adding a hydroxyphenyl carboxylic acid, a tyrosine ethyl ester, hydroxybenzotriazole hydrate and a solvent and stirring to produce a first solution. EDCI HCl is added to the first solution to produce a first mixture. Ethyl acetate is added to the first mixture to produce a second mixture. The second mixture is added to sodium chloride to produce a third mixture having layer separation. An aqueous layer is removed from the third mixture. The third mixture is extracted with reagents after the aqueous layer has been removed from the third mixture to produce a fourth mixture. Magnesium sulfate is added to the fourth mixture to produce a fifth mixture. The fifth mixture is filtered to produce filtrate. The filtrate is concentrated. Crystallization of the concentrated filtrate is induced. Methylene chloride is added to the crystallized filtrate to produce a solid product.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: October 15, 2019
    Assignee: Medtronic, Inc.
    Inventors: Satish Pulapura, Fatima Buevich, Xiangji Chen, Suping Lyu
  • Patent number: 10420864
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a first component having a first substrate and a second component having a second substrate. The second component is positioned within the first component. One of the first and second substrates includes a hemostatic agent and the other of the first and second substrates includes an active pharmaceutical ingredient. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: September 24, 2019
    Assignee: MEDTRONIC, INC.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie S. Soskin, Franklin R. Mansfield, Kai R. Worrell, Charlie Wood
  • Patent number: 10314951
    Abstract: A kit includes a mesh substrate and a polymer that is fixed to the mesh substrate. The polymer includes an active agent that is configured to elute over time. The kit further includes a hemostatic agent. The hemostatic agent is separate from the mesh substrate and the polymer. Systems and methods are disclosed.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: June 11, 2019
    Assignee: Medtronic, Inc.
    Inventors: Xiangji Chen, Satish Pulapura, Fatima Buevich
  • Publication number: 20190125938
    Abstract: A kit includes a mesh substrate and a polymer that is fixed to the mesh substrate. The polymer includes an active agent that is configured to elute over time. The kit further includes a hemostatic agent. The hemostatic agent is separate from the mesh substrate and the polymer. Systems and methods are disclosed.
    Type: Application
    Filed: April 26, 2018
    Publication date: May 2, 2019
    Applicant: TYRX, Inc.
    Inventors: Xiangji Chen, Satish Pulapura, Fatima Buevich
  • Publication number: 20190030218
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a substrate and a hemostatic agent. The substrate includes a first piece and a second piece that is joined with the first piece. The first piece includes the hemostatic agent and the second piece includes an active pharmaceutical ingredient. Kits, systems and methods are disclosed.
    Type: Application
    Filed: May 1, 2017
    Publication date: January 31, 2019
    Applicant: TYRX, Inc.
    Inventors: SATISH PULAPURA, FATIMA BUEVICH, JORIE S. SOSKIN, FRANKLIN R. MANSFIELD, KAI R. WORRELL, CHARLIE WOOD, JORGE ALBERTO TREVINO BLANCO
  • Publication number: 20180354892
    Abstract: A method for preparing diphenol compounds includes adding a hydroxyphenyl carboxylic acid, a tyrosine ethyl ester, hydroxybenzotriazole hydrate and a solvent and stirring to produce a first solution. EDCl HCl is added to the first solution to produce a first mixture. Ethyl acetate is added to the first mixture to produce a second mixture. The second mixture is added to sodium chloride to produce a third mixture having layer separation. An aqueous layer is removed from the third mixture. The third mixture is extracted with reagents after the aqueous layer has been removed from the third mixture to produce a fourth mixture. Magnesium sulfate is added to the fourth mixture to produce a fifth mixture. The fifth mixture is filtered to produce filtrate. The filtrate is concentrated. Crystallization of the concentrated filtrate is induced. Methylene chloride is added to the crystallized filtrate to produce a solid product.
    Type: Application
    Filed: May 7, 2018
    Publication date: December 13, 2018
    Applicant: TYRX, Inc.
    Inventors: Satish Pulapura, Fatima Buevich, Xiangji Chen, Suping Lyu
  • Publication number: 20180355103
    Abstract: A method for preparing tyrosine derived polyarylates includes combining a desaminotyrosyl-tyrosine ethyl ester, a desaminotyrosyl-tyrosine benzylester, succinic acid and a catalyst in a flask to produce a first mixture. Methylene chloride is added to the first mixture to produce a first suspension. Diisopropylcarbodiimide (DIPC) is added to the first mixture to produce a first solution. The first solution is added to a non-solvent to produce a precipitate. The precipitate is dissolved in methylene chloride to form a polymer solution. The polymer solution is blended with a slurry to produce polymer shreds. The polymer shreds are blended with a second slurry to produce a tyrosine derived polyarylate.
    Type: Application
    Filed: May 7, 2018
    Publication date: December 13, 2018
    Applicant: TYRX, Inc.
    Inventors: SATISH PULAPURA, FATIMA BUEVICH, XIANGJI CHEN, SUPING LYU
  • Publication number: 20180355104
    Abstract: A method for hydrogenating tyrosine derived polyarylates includes dissolving a second polyarylate with DMF in a flask to produce a first solution. A catalyst is added to the first solution to produce a polymer solution. The polymer solution is filtered through a Celite bed to produce a filtrate. The filtrate is added to water and stirred to precipitate the polyarylate.
    Type: Application
    Filed: May 7, 2018
    Publication date: December 13, 2018
    Applicant: Tyrx, Inc.
    Inventors: SATISH PULAPURA, DAN THANH LE, XIANGJI CHEN, SUPING LYU, FATIMA BUEVICH
  • Publication number: 20180256306
    Abstract: The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use.
    Type: Application
    Filed: May 9, 2018
    Publication date: September 13, 2018
    Applicant: Tyrx, Inc.
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Patent number: 10034969
    Abstract: A kit includes a mesh substrate and a polymer that is fixed to the mesh substrate. The polymer includes an active agent that is configured to elute over time. The kit further includes a hemostatic agent. The hemostatic agent is separate from the mesh substrate and the polymer. Systems and methods are disclosed.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: July 31, 2018
    Assignee: TYRX, Inc.
    Inventors: Xiangji Chen, Satish Pulapura, Fatima Buevich
  • Publication number: 20180193540
    Abstract: A medical prosthesis includes a tube having a length between a first end and a second end. The tube includes a polymer and at least one drug. The tube is configured to be manipulated to selectively increase and decrease the length of the tube. Kits, systems and methods are disclosed.
    Type: Application
    Filed: December 26, 2017
    Publication date: July 12, 2018
    Applicant: TYRX, Inc.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie Soskin, Jonathan Sturtevant
  • Patent number: 9987400
    Abstract: A kit includes a mesh substrate and a polymer that is fixed to the mesh substrate. The polymer includes an active agent that is configured to elute over time. The kit further includes a hemostatic agent. The hemostatic agent is separate from the mesh substrate and the polymer. Systems and methods are disclosed.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: June 5, 2018
    Assignee: TYRX, Inc.
    Inventors: Xiangji Chen, Satish Pulapura, Fatima Buevich