Patents by Inventor Fatima Buevich

Fatima Buevich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9987400
    Abstract: A kit includes a mesh substrate and a polymer that is fixed to the mesh substrate. The polymer includes an active agent that is configured to elute over time. The kit further includes a hemostatic agent. The hemostatic agent is separate from the mesh substrate and the polymer. Systems and methods are disclosed.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: June 5, 2018
    Assignee: TYRX, Inc.
    Inventors: Xiangji Chen, Satish Pulapura, Fatima Buevich
  • Patent number: 9987116
    Abstract: The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: June 5, 2018
    Assignee: TYRX, Inc.
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Patent number: 9919080
    Abstract: A kit includes a mesh substrate and a polymer that is fixed to the mesh substrate. The polymer includes an active agent that is configured to elute over time. The kit further includes a hemostatic agent. The hemostatic agent is separate from the mesh substrate and the polymer. Systems and methods are disclosed.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: March 20, 2018
    Assignee: TYRX, INC.
    Inventors: Xiangji Chen, Satish Pulapura, Fatima Buevich
  • Patent number: 9848955
    Abstract: Biodegradable and resorbable polymer pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices (IMDs), i.e., a pouch, covering, or other receptacle capable of encasing, surrounding and/or holding the CRM or other IMD for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other IMD. Optionally, the biodegradable and resorbable pouches of the invention include one or more drugs in the polymer matrix to provide prophylactic effects and alleviate side effects or complications associated with the surgery or implantation of the CRM or other IMD.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: December 26, 2017
    Assignee: TYRX, Inc.
    Inventors: Fatima Buevich, Arikha Moses, Frank Do, William McJames, William Edelman, Mason Diamond
  • Patent number: 9839628
    Abstract: The invention generally relates to compositions and methods for preventing sternal wound infections, such as mediastinitis. In certain embodiments, the invention provides an antimicrobial composition including at least one bioresorbable polymer, such as a tyrosine-derived polyesteramide, and at least one antimicrobial agent, in which the composition is adapted to be topically applied to an esophageal perforation in a subject or a median sternotomy incision site in the subject, and in which the at least one antimicrobial agent is present in an amount effective to inhibit development of mediastinitis in the subject.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: December 12, 2017
    Assignee: TYRX, Inc.
    Inventors: Raman Bahulekar, Arikha Moses, Satish Pulapura, William C. McJames, II, Fatima Buevich
  • Publication number: 20170319755
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a substrate formed from a first material and a second material. At least one of the first and second materials includes a hemostatic agent. Kits, systems and methods are disclosed.
    Type: Application
    Filed: May 1, 2017
    Publication date: November 9, 2017
    Applicant: TYRX, Inc.
    Inventors: SATISH PULAPURA, Fatima Buevich, Jorie S. Soskin, Franklin R. Mansfield, Kai R. Worrell, Charlie Wood, Jorge Alberto Trevino Blanco
  • Publication number: 20170319754
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a first component having a first substrate and a second component having a second substrate. The second component is positioned within the first component. One of the first and second substrates includes a hemostatic agent and the other of the first and second substrates includes an active pharmaceutical ingredient. Kits, systems and methods are disclosed.
    Type: Application
    Filed: May 1, 2017
    Publication date: November 9, 2017
    Applicant: TYRX, Inc.
    Inventors: SATISH PULAPURA, FATIMA BUEVICH, JORIE S. SOSKIN, FRANKLIN R. MANSFIELD, KAI R. WORRELL, CHARLIE WOOD
  • Publication number: 20170319756
    Abstract: An anchorage device is provided that is configured to surround an implantable medical device. The anchorage device includes a substrate having a hemostatic agent and an active pharmaceutical ingredient selectively positioned on the substrate. Kits, systems and methods are disclosed.
    Type: Application
    Filed: May 1, 2017
    Publication date: November 9, 2017
    Applicant: TYRX, Inc.
    Inventors: Satish Pulapura, Fatima Buevich, Jorie S. Soskin, Franklin R. Mansfield, Kal R. Worrell, Charlie Wood, Jorge Alberto Trevino Blanco
  • Publication number: 20170319193
    Abstract: An anchorage device includes a substrate extending along a longitudinal axis between a first end having a first bonding area and an opposite second end having a second bonding area. The substrate has a third bonding area between the first and second bonding areas. Kits, systems and methods are disclosed.
    Type: Application
    Filed: May 1, 2017
    Publication date: November 9, 2017
    Applicant: TYRX, Inc
    Inventors: Satish PULAPURA, Fatima BUEVICH, Archana RAJARAM, Jonathan M. MAHONEY, Dan Thanh Le .
  • Publication number: 20160331505
    Abstract: The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use.
    Type: Application
    Filed: July 26, 2016
    Publication date: November 17, 2016
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Patent number: 9486560
    Abstract: Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: November 8, 2016
    Assignee: TYRX, Inc.
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Patent number: 9457129
    Abstract: The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: October 4, 2016
    Assignee: TYRX, INC.
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Publication number: 20150273118
    Abstract: Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness.
    Type: Application
    Filed: September 23, 2013
    Publication date: October 1, 2015
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Publication number: 20150238262
    Abstract: Biodegradable and resorbable polymer pouches are described for use with cardiac rhythm mamagent devices (CRMs) and other implantable medical devices (IMDs), i.e., a pouch, covering, or other receptacle capable of encasing, surrounding and/or holding the CRM or other IMD for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other IMD. Optionally, the biodegradable and resorbable pouches of the invention include one or more drugs in the polymer matrix to provide prophylactic effects and alleviate side effects or complications associated with the surgery or implantation of the CRM or other IMD.
    Type: Application
    Filed: March 10, 2015
    Publication date: August 27, 2015
    Inventors: Dr. Fatima Buevich, Arikha Moses, Frank Do, William McJames, William Edelman, Mason Diamond
  • Publication number: 20150150789
    Abstract: An antimicrobial composition and methods of making the same are disclosed herein. In one aspect of the invention, an antimicrobial composition comprising one or more bioresorbable polymer drug particles and at least one polymer, the polymer drug particle including at least one bioresorbable polymer and at least one antimicrobial agent, wherein the composition is formulated for topical application to a surgical incision site in the subject.
    Type: Application
    Filed: November 10, 2014
    Publication date: June 4, 2015
    Inventors: Raman Bahulekar, William McJames, Fatima Buevich, Satish Pulapura
  • Publication number: 20150150986
    Abstract: A composition comprising a polymer and at least one active agent, wherein the composition is formulated for topical application and shows thermally reversible behavior or inverse thermally reversible behavior. The active agent of the composition is an antimicrobial, an anti-inflammatory agent, anesthetic or mixtures thereof. A method of preparing the composition is also provided.
    Type: Application
    Filed: November 10, 2014
    Publication date: June 4, 2015
    Inventors: Raman Bahulekar, William McJames, Fatima Buevich, Satish Pulapura
  • Patent number: 9023114
    Abstract: Biodegradable and resorbable polymer pouches are described for use with cardiac rhythm mamagent devices (CRMs) and other implantable medical devices (IMDs), i.e., a pouch, covering, or other receptacle capable of encasing, surrounding and/or holding the CRM or other IMD for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other IMD. Optionally, the biodegradable and resorbable pouches of the invention include one or more drugs in the polymer matrix to provide prophylactic effects and alleviate side effects or complications associated with the surgery or implantation of the CRM or other IMD.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: May 5, 2015
    Assignee: Tyrx, Inc.
    Inventors: Fatima Buevich, Frank Do, William McJames, William Edelman, Arikha Moses, Mason Diamond
  • Publication number: 20150086604
    Abstract: Biodegradable polymer-coated surgical meshes formed into pouches are described for use with cardiac rhythm management devices (CRMs) and other implantable medical devices. Such meshes are formed into a receptacle, e.g., a pouch or other covering, capable of encasing, surrounding and/or holding the cardiac rhythm management device or other implantable medical device for the purpose of securing it in position, inhibiting or reducing bacterial growth, providing pain relief and/or inhibiting scarring or fibrosis on or around the CRM or other implantable medical device. Preferred embodiments include surgical mesh pouches coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness.
    Type: Application
    Filed: September 23, 2013
    Publication date: March 26, 2015
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy
  • Patent number: 8652525
    Abstract: This invention provides biodegradable, sustained-release pharmaceutical compositions of non-steroidal, anti-inflammatory drugs (NSAIDs) formulated with biocompatible, biodegradable tyrosine-derived polyarylates. The compositions are particularly suitable for localized delivery of NSAIDs for various disease states. For example, implantation of the compositions at the site of surgery leads to relatively high local concentrations of the NSAID to reduce or alleviate post-surgical pain. Long term zero order release of certain NSAIDs can also be provided by with certain polymer formulations.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: February 18, 2014
    Assignee: TYRX, Inc.
    Inventors: Arikha Moses, Fatima Buevich, Satish Pulapura, Arvind Viswanathan
  • Publication number: 20140046350
    Abstract: The present invention relates to medical prostheses and methods of manufacturing those devices. In particular, the prostheses are temporarily stiffened meshes with particular coatings to provide initial stiffness and thereby permit easier surgical handling for treatment or reconstruction of soft tissue defects. Preferred embodiments include surgical meshes coated with one or more biodegradable polymers that can act as a stiffening agent by coating the filaments or fibers of the mesh to temporarily immobilize the contact points of those filaments or fibers and/or by increasing the stiffness of the mesh by at least 1.1 times its original stiffness. The devices of the invention can also provide relief from various post-operative complications associated with their implantation, insertion or surgical use.
    Type: Application
    Filed: September 23, 2013
    Publication date: February 13, 2014
    Applicants: TYRX, INC., TYRX PHARMA, INC.
    Inventors: Fatima Buevich, Frank Do, William McJames, Satish Pulapura, William Edelman, Arikha Moses, Mason Diamond, Shari Timothy