Patents by Inventor Fei Han
Fei Han has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12716382Abstract: A combustor for a turbine engine. The combustor includes a combustion chamber and a damper. The combustion chamber is configured to combust a mixture of a fuel flow and a compressed air flow to generate combustion products. The damper is in fluid communication with the combustion chamber to damp an instability generated in the combustion chamber by the combustion products. The damper includes a damper cavity and one or more damper necks. The damper necks provide fluid communication between the damper cavity and the combustion chamber. The damper necks extend along a damper neck longitudinal centerline axis and include a tapered portion that extends at a damper neck taper angle ? with respect to the damper neck longitudinal centerline axis.Type: GrantFiled: October 15, 2025Date of Patent: August 25, 2026Assignee: GENERAL ELECTRIC COMPANYInventors: Fei Han, Nicholas Arthur Magina
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Publication number: 20260201044Abstract: Disclosed are antibodies and fragments thereof that target the A-domain of Neuropilin-1 (Nrp1A). Also disclosed are methods of using the anti-Nrp1A antibodies for the treatment of various diseases or disorders.Type: ApplicationFiled: January 5, 2026Publication date: July 16, 2026Inventors: Nina ZIPPEL, Pankaj GUPTA, Fei HAN, Yining HUANG, Sarah LOW, Juergen PRESTLE, Leo THOMAS
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Patent number: 12681279Abstract: An optical device and the prism module thereof are provided. The prism module includes a first prism, a second prism, a third prism and a fourth prism. The second prism is disposed beside the first prism. The second prism is attached to the third prism and the fourth prism. In operation, first visible light enters the first prism, is reflected plural times in the first prism, enters the second prism and then the fourth prism, is reflected at least one time in the fourth prism, returns to the second prism, is reflected at least one time in the second prism, enters the third prism and exits from the third prism. Also, second visible light enters the third prism, is reflected plural times in the third prism and exits from the third prism.Type: GrantFiled: June 27, 2023Date of Patent: July 14, 2026Assignees: SINTAI OPTICAL (SHENZHEN) CO., LTD., ASIA OPTICAL CO., INC.Inventors: Hua-Tang Liu, Sheng Luo, Yue-Ye Chen, Lian Zhao, Fei Han
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Publication number: 20260078185Abstract: The present application provides anti-VISTA constructs that bind to VISTA (e.g., anti-VISTA antibodies), nucleic acid molecules encoding an amino acid sequence of the anti-VISTA, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of preparing the anti-VISTA construct, pharmaceutical compositions containing the anti-VISTA construct, and methods of using the anti-VIS-TA construct or compositions.Type: ApplicationFiled: September 7, 2023Publication date: March 19, 2026Inventors: Zirong CHEN, Fei HAN, Jian LI, Angela NORTON, Zhinan XIA
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Publication number: 20260070984Abstract: The present invention relates to new anti-PD-1 (Programmed cell death 1) antibodies and antigen-binding fragments thereof for therapeutic and diagnostic methods and compositions using them.Type: ApplicationFiled: April 24, 2025Publication date: March 12, 2026Inventors: David A. BLAIR, Nicole K. GARAFFA, Pankaj GUPTA, Priyanka GUPTA, Fei HAN, Aaron Timothy KARLAK, Dongmei LIU, Mouhamadou Lamine MBOW, Joseph A. MOZDZIERZ, Kerry L.M. RALPH, Abdulsalam SHAABAN, Helen Haixia WU, Guangwei YANG
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Patent number: 12569147Abstract: A liquid reactivity detection device and method. The liquid reactivity detection device includes: a breathing signal acquisition module, a hemodynamic signal acquisition module and a liquid reactivity detection module. The breathing signal acquisition module and the hemodynamic signal acquisition module work in cases where the subject is in any one of the following breathing modes: a spontaneous breathing mode, a spontaneous breathing combined with mechanical ventilation mode, and a mechanical ventilation mode. The hemodynamic signal acquisition module is configured to acquire at least one hemodynamic signal of the subject. The breathing signal acquisition module is configured to acquire at least one breathing signal of the subject. The liquid reactivity detection module is configured to determine the liquid reactivity of the subject according to the breathing signal and the hemodynamic signal.Type: GrantFiled: September 30, 2021Date of Patent: March 10, 2026Assignee: SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Bailei Sun, Fei Han, Fei Zhang, Chunliu Xie
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Patent number: 12540187Abstract: Disclosed are antibodies and fragments thereof that target the A-domain of Neuropilin-1 (Nrp1A). Also disclosed are methods of using the anti-Nrp1A antibodies for the treatment of various diseases or disorders.Type: GrantFiled: April 7, 2023Date of Patent: February 3, 2026Assignee: Boehringer Ingelheim International GmbHInventors: Nina Zippel, Pankaj Gupta, Fei Han, Yining Huang, Sarah Low, Juergen Prestle, Leo Thomas
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Publication number: 20250354515Abstract: A gas turbine engine having a compressor section for compressing air flowing therethrough to provide a compressed air flow, a combustor including a combustion chamber, the combustion chamber configured to combust a mixture of a fuel flow and the compressed air flow to generate combustion products, a turbine section having at least one turbine driven by the combustion products, and a damper in fluid communication with the combustion chamber to dampen an instability generated in the combustion chamber by the combustion products. The damper defined by nds?nƒp, ap?dpn, and ab?dp?*dp?ea, where nds is a number of damper cavities in series, nƒp is a number of discrete frequencies to be damped, ap is an acoustic damping potential, dpn is a neck open area ratio, ab is an acoustic damping broadness, dp? is a damper volume, and dp?ea is a damper volume expansion angle.Type: ApplicationFiled: May 15, 2024Publication date: November 20, 2025Inventors: Fei HAN, Nicholas Arthur MAGINA
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Publication number: 20250354516Abstract: A gas turbine engine includes a compressor section for compressing air flowing therethrough to provide a compressed air flow, a combustor including a combustion chamber, the combustion chamber configured to combust a mixture of a fuel flow and the compressed air flow to generate combustion products, and a turbine section having at least one turbine driven by the combustion products. The gas turbine engine includes a multicavity damper in fluid communication with the combustion chamber to dampen an instability generated in the combustion chamber by the combustion products. The multicavity damper has a plurality of cavity volumes and the length of each cavity volume is different.Type: ApplicationFiled: July 18, 2025Publication date: November 20, 2025Inventors: Nicholas Arthur Magina, Fei Han
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Publication number: 20250341310Abstract: A combustor for a turbine engine includes a wall defining a combustion chamber, and an acoustic damper. The acoustic damper includes a housing in fluid communication with the combustion chamber through an opening provided in the wall, the housing defining a cavity and having one or more neck holes in fluid communication with the combustion chamber, and a mechanism configured to vary a damping acoustic frequency of the acoustic damper so as to vary the damping acoustic frequency of the acoustic damper to align with an acoustic frequency of acoustic vibrations generated in the combustion chamber to attenuate an acoustic instability within the combustion chamber.Type: ApplicationFiled: May 2, 2024Publication date: November 6, 2025Inventors: Nicholas Arthur Magina, Fei Han, Bassam Sabry Mohammad Abdelnabi, Ramal Janith Samarasinghe, Sibtosh Pal
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Patent number: 12442573Abstract: An air conditioning system includes an outdoor unit and an indoor unit. The outdoor unit includes a compressor, an outdoor heat exchanger, a first expansion valve, a third expansion valve, and a subcooling heat exchanger. The indoor unit includes an indoor heat exchanger and a second expansion valve. In a cooling mode, the outdoor unit is configured to adjust an opening degree of the first expansion valve according to a relationship between a first difference and a first preset value; adjust an opening degree of the second expansion valve according to a relationship between a second difference and a second preset value; and adjust an opening degree of the third expansion valve according to a relationship between a third difference and a third preset value.Type: GrantFiled: January 5, 2024Date of Patent: October 14, 2025Assignee: QINGDAO HISENSE HITACHI AIR-CONDITIONING SYSTEMS CO., LTD.Inventors: Peng Yan, Min Zhou, Yang Sun, Fei Han
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Patent number: 12366203Abstract: A gas turbine engine includes a compressor section for compressing air flowing therethrough to provide a compressed air flow, a combustor including a combustion chamber, the combustion chamber configured to combust a mixture of a fuel flow and the compressed air flow to generate combustion products, and a turbine section having at least one turbine driven by the combustion products. The gas turbine engine includes a multicavity damper in fluid communication with the combustion chamber to dampen an instability generated in the combustion chamber by the combustion products. The multicavity damper has a plurality of cavity volumes and the length of each cavity volume is different.Type: GrantFiled: May 15, 2024Date of Patent: July 22, 2025Assignee: GENERAL ELECTRIC COMPANYInventors: Nicholas Arthur Magina, Fei Han
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Patent number: 12312405Abstract: The present invention relates to new anti-PD-1 (Programmed cell death 1) antibodies and antigen-binding fragments thereof for therapeutic and diagnostic methods and compositions using them.Type: GrantFiled: May 24, 2021Date of Patent: May 27, 2025Inventors: David A. Blair, Nicole K. Garaffa, Pankaj Gupta, Priyanka Gupta, Fei Han, Aaron Timothy Karlak, Dongmei Liu, Mouhamadou Lamine Mbow, Joseph A. Mozdzierz, Kerry L. M. Ralph, Abdulsalam Shaaban, Helen Haixia Wu, Guangwei Yang
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Patent number: 12296931Abstract: The present disclosure discloses a bionic cuttlefish-typed underwater detection robot, including a bionic “cuttlefish”-typed body structure, a piezoelectric energy capture device, a circuit rectification and storage assembly and a power control assembly. The bionic “cuttlefish”-typed body structure includes a head and a main body; the piezoelectric energy capture device includes piezoelectric ceramic elements arranged around the main body and PVDF floating belts, and an end of each piezoelectric ceramic element is connected to a spherical spoiler component, the PVDF floating belts are evenly distributed at a tail end of the main body. The present disclosure adopts piezoelectric ceramic elements with spoiler components and PVDF floating belts to generate electricity, converts wave energy and ocean current energy into electric energy, powers the power control assembly of the detection robot.Type: GrantFiled: November 20, 2024Date of Patent: May 13, 2025Inventors: Baoqi Li, Yuzhu Jiang, Xianshun Guo, Fei Han, Haiqing Zheng, Tonghao Zhang, Fu Shi, Pengyu Zhu, Jiahui Tang, Angyue Lv
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Patent number: 12293437Abstract: Systems and methods include segmentation of a first image of a subject to identify locations of anatomical structures of the subject, determination of a region of interest of the subject based on the locations of anatomical structures, determination of a coil-mixing matrix based on the region of interest, control of an MR scanner to acquire radial trajectory k-space data of the subject from each of a plurality of RF coils of the MR scanner, application of the coil-mixing matrix to the radial trajectory k-space data of the subject acquired from each of the plurality of RF coils to generate first radial trajectory k-space data, reconstruction of a second image of the subject based on the first radial trajectory k-space data, and display of the second image.Type: GrantFiled: February 8, 2023Date of Patent: May 6, 2025Assignees: Siemens Healthineers AG, The General Hospital CorporationInventors: Fei Han, Stephen Farman Cauley, Vibhas S. Deshpande
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Publication number: 20250074563Abstract: The present disclosure discloses a bionic cuttlefish-typed underwater detection robot, including a bionic “cuttlefish”-typed body structure, a piezoelectric energy capture device, a circuit rectification and storage assembly and a power control assembly. The bionic “cuttlefish”-typed body structure includes a head and a main body; the piezoelectric energy capture device includes piezoelectric ceramic elements arranged around the main body and PVDF floating belts, and an end of each piezoelectric ceramic element is connected to a spherical spoiler component, the PVDF floating belts are evenly distributed at a tail end of the main body. The present disclosure adopts piezoelectric ceramic elements with spoiler components and PVDF floating belts to generate electricity, converts wave energy and ocean current energy into electric energy, powers the power control assembly of the detection robot.Type: ApplicationFiled: November 20, 2024Publication date: March 6, 2025Applicant: Shijiazhuang Tiedao UniversityInventors: Baoqi Li, Yuzhu Jiang, Xianshun Guo, Fei Han, Haiqing Zheng, Tonghao Zhang, Fu Shi, Pengyu Zhu, Jiahui Tang, Angyue Lv
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Patent number: 12233019Abstract: This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.Type: GrantFiled: May 22, 2019Date of Patent: February 25, 2025Assignees: PEKING UNION MEDICAL COLLEGE HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES, SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.Inventors: Jun Xu, Xuezhong Yu, Fei Han, Liangliang Zheng, Cheng Wang, Xiaocui Zhang, Chen Li, Jingming Yang, Xingliang Jin, Yangyang Fu, Dongqi Yao
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Patent number: 12228714Abstract: An optical system includes an objective lens module, an image inverting module, and an eyepiece module. The objective lens module includes a first lens group, a second lens group, a third lens group, a fourth lens group, and a fifth lens group. The optical system satisfies at least one of the following conditions: 0.45?LG4D/LG1D?0.8; 0.015 mm?1?1/fG3?0.045 mm?1; 0.045 mm?1?|1/fG4|?0.07 mm?1; 0.35?|fG4/fG3|?0.75; 0.15?fG1/f?1.6; wherein LG4D is an effective optical diameter of the fourth lens group, LG1D is an effective optical diameter of the first lens group, fG1 is an effective focal length of the first lens group, fG3 is an effective focal length of the third lens group, fG4 is an effective focal length of the fourth lens group, and f is an effective focal length of the objective lens module.Type: GrantFiled: December 22, 2022Date of Patent: February 18, 2025Assignees: SINTAI OPTICAL (SHENZHEN) CO., LTD., ASIA OPTICAL CO., INC.Inventors: Fang-Li Ma, Bin Liu, Fei Han, Ling-Wei Zhao, Yue-Ye Chen, Hua-Tang Liu
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Publication number: 20250051460Abstract: This invention relates to binding molecules that bind specifically Vascular Endothelial Growth Factor (VEGF) and Tropomyosin receptor kinase B (TrkB) and their use in medicine, pharmaceutical compositions comprising the same, and methods of using the same as agents for treatment and/or prevention of diseases of the eye.Type: ApplicationFiled: August 19, 2024Publication date: February 13, 2025Inventors: Peter Michael BENZ, Remko Alexander BAKKER, Holger FUCHS, Fei HAN, Sandeep KUMAR, Sarah LOW, Justin M. SCHEER, Leo THOMAS
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Patent number: 12158981Abstract: Systems and techniques for persistent calibration of an electronic device configured to implement an extended reality (XR) system involve estimating and validating visual-inertial odometry (VIO) calibration parameters during an active XR session of the electronic device. Validating the estimated VIO calibration parameters involves performing a strict calibration qualification of the estimated VIO calibration parameters using a thresholding module, machine learning module, or both. An initial calibration qualification is performed concurrently with the strict calibration qualification based on VIO performance. If the estimated VIO calibration parameters pass the strict calibration qualification and initial calibration qualification, they are stored for use to calibrate the device in future XR sessions. Persistent calibration of time alignment between the inertial management unit and the image sensor of the electronic device is also performed during active XR sessions upon detection of time alignment issues.Type: GrantFiled: September 8, 2021Date of Patent: December 3, 2024Assignee: GOOGLE LLCInventors: Chao X. Guo, Fei Han, Sazzadur Rahman, Luca Ballan, Junyang Lu