Abstract: The present invention relates to antibodies and fragments thereof that target semaphorin 3A (Sema3A). More specifically, anti-Sema3A antibodies and methods of use for the treatment of various diseases or disorders are disclosed.

Abstract: An imaging system includes determination of a first gradient-modulated offset-independent adiabaticity pulse associated with a first bandwidth and a first gradient strength, determination of a second gradient-modulated offset-independent adiabaticity pulse associated with a second bandwidth less than the first bandwidth and a second gradient strength less than the first gradient strength, determination of a third asymmetric adiabatic pulse based on the first gradient-modulated offset-independent adiabaticity pulse and the second gradient-modulated offset-independent adiabaticity pulse, and control of a radio frequency system and gradient system to apply the third asymmetric adiabatic pulse to patient tissue.

Abstract: An imaging system includes determination of a first gradient-modulated offset-independent adiabaticity pulse associated with a first bandwidth and a first gradient strength, determination of a second gradient-modulated offset-independent adiabaticity pulse associated with a second bandwidth less than the first bandwidth and a second gradient strength less than the first gradient strength, determination of a third asymmetric adiabatic pulse based on the first gradient-modulated offset-independent adiabaticity pulse and the second gradient-modulated offset-independent adiabaticity pulse, and control of a radio frequency system and gradient system to apply the third asymmetric adiabatic pulse to patient tissue.

Abstract: An inline fluid damper device comprises a flow-through conduit configured to be placed inside a larger exterior conduit through which a fluid flows. The flow-through conduit is elongated and extending around a center axis. The damper device also comprising an indirect flow conduit coupled with the flow-through conduit. The indirect flow conduit is also configured to be placed inside the larger exterior conduit. The flow-through conduit and the indirect flow conduit are configured to dampen one or more flow fluctuations or pressure fluctuations in the fluid flowing in the larger exterior conduit by dividing the fluid into a first portion that flows along the center axis through the flow-through conduit and a second portion that concurrently flows outside of the flow-through conduit along the center axis and along a different direction.

Abstract: A system for performing magnetic resonance imaging (MRI) of a subject has a pulse sequence system that generates a pulse sequence and has a gradient system, a plurality of gradient coils, a radio-frequency system, and a plurality of RF coils. The pulse sequence system causes the subject to emit MR signals which are captured as k-space data. The system also has a k-space ordering processor that collects first k-space data and second k-space data, an MR signal modeler that generates a signal variation model, and a compensation module that applies the signal variation model to the second k-space data collected to produce compensated k-space data. A display processor reconstructs the compensated k-space data into an image of the subject. The compensated data accounts for variation in magnetization during the pulse sequence and k-space data collection to reduce artifacts in the images.

Abstract: A shift register including an input circuit, an output circuit, a first output control circuit, a second output control circuit, a reset circuit, a first reset control circuit, a second reset control circuit, and an energy-storing circuit. The first output control circuit is configured to transfer a clock signal present at a third clock signal terminal to a first node in response to the clock signal at the third clock signal terminal being active. The second output control circuit is configured to transfer a voltage present at a first voltage terminal to the first node in response to a clock signal at a fourth clock signal terminal being active.

Abstract: A shift register including an input circuit, an output circuit, a first output control circuit, a second output control circuit, a reset circuit, a first reset control circuit, a second reset control circuit, and an energy-storing circuit. The first output control circuit is configured to transfer a clock signal present at a third clock signal terminal to a first node in response to the clock signal at the third clock signal terminal being active. The second output control circuit is configured to transfer a voltage present at a first voltage terminal to the first node in response to a clock signal at a fourth clock signal terminal being active.

Abstract: This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: 3D cine MR angiography systems and methods are disclosed for use during the steady state intravascular distribution phase of ferumoxytol. The 3D cine MRA technique enables improved delineation of cardiac anatomy in pediatric patients undergoing cardiovascular MRI.

Abstract: In one aspect the present subject matter is directed to a system for suppressing acoustic noise within a combustion section of a gas turbine. The system includes at least one static structure disposed forward of a combustion chamber defined within the combustion section. The static structure at least partially defines a diffuser cavity upstream of the combustion chamber. A baffle plate is coupled to the static structure. The baffle plate and the static structure at least partially define an air plenum within the combustion section forward of the combustion chamber. The baffle plate includes an aperture that provides for fluid communication between the diffuser cavity and the air plenum. The at least one static structure and the baffle plate define a Helmholtz resonator within the combustion section.

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: The present disclosure is directed to a fuel manifold assembly for a gas turbine engine. The fuel manifold assembly defines a walled conduit through which a fuel flows in a fuel passage. The walled conduit defines a first end and a second end opposite of the first end along a length of the walled conduit. The fuel manifold assembly includes an exit manifold to which a fuel nozzle attaches. The fuel manifold assembly includes a damper assembly coupled to the walled conduit of the fuel manifold assembly. The damper assembly includes a walled tube extended from the walled conduit. The damper assembly further includes a walled enclosure defining a damper cavity therein. The damper cavity is in fluid communication with a damper passage defined within the walled tube, and the damper passage is in fluid communication with the fuel passage.

Abstract: A clickable control pad, comprising a top part (101), a frame (103), and a mechanical structure (101a, 103b) for guiding a movement of the top part (101) with regard to the frame (103) in a direction perpendicular to the frame (103).

Abstract: This disclosure relates to methods, devices and systems for real-time recognition of restoration of spontaneous circulation (ROSC) in the cardio-pulmonary resuscitation (CPR) process. Recognition mechanisms in both time domain and frequency domain are provided for the ROSC recognition, where the time-domain recognition logic may detect the ROSC by recognizing envelope features of sampled signals in the time domain, and the frequency-domain recognition logic may detect the ROSC by recognizing spectral peaks at different frequency points continuously or significant variations of amplitude of spectral peaks in the frequency spectrum.

Abstract: An inline fluid damper device comprises a flow-through conduit configured to be placed inside a larger exterior conduit through which a fluid flows. The flow-through conduit is elongated and extending around a center axis. The damper device also comprising an indirect flow conduit coupled with the flow-through conduit. The indirect flow conduit is also configured to be placed inside the larger exterior conduit. The flow-through conduit and the indirect flow conduit are configured to dampen one or more flow fluctuations or pressure fluctuations in the fluid flowing in the larger exterior conduit by dividing the fluid into a first portion that flows along the center axis through the flow-through conduit and a second portion that concurrently flows outside of the flow-through conduit along the center axis and along a different direction.

Abstract: Apparatus and method are provided for reducing acoustical noise when cooling a device, such as a lamp system. The apparatus includes at least a set of a first synthetic jet and a second synthetic jet. The first and second synthetic jets are responsive to respective actuating signals having a phase difference (e.g., 180°) between one another chosen to reduce acoustic noise produced by the first and second synthetic jets when cooling the device.

Abstract: A method for calculating physiological parameters includes: selecting a section of time domain signal corresponding to at least one signal of red light and infrared light obtained by sampling, and performing a conversion from time domain to frequency domain to obtain a corresponding frequency domain signal; selecting all rational frequency spectrum peak information, calculating energy information of selected reasonable frequency spectrum peaks, and forming a frequency spectrum peak energy ratio sequence; constructing a stability coefficient according to the frequency spectrum peak energy ratio sequence, and if the stability coefficient is low, constructing a compensation coefficient by using the frequency spectrum peak energy ratio sequence; and compensating for at least one of the time domain signal and the frequency domain signal by using the compensation coefficient, and calculating based on at least one of the compensated time domain signal and the frequency domain signal to obtain the physiological param