Abstract: The disclosure relates to technology for secure compute. One aspect includes a network device, comprising a non-transitory memory comprising instructions; and one or more processors in communication with the non-transitory memory storage. The one or more processors execute the instructions to receive and process routing requests in a network; send an indication into the network that the network device is able to perform secure computes; perform a secure compute based on an input received via the network from an input device; ensure that a result of the secure compute is trusted as a correct result of the secure compute; and provide the trusted result of the secure compute to a result device connected to the network.

Abstract: A device (“the ExoTIC device”) for the isolation of extracellular vesicles from an extracellular vesicle-containing sample in which the sample is flowed through a membrane in a flow chamber to capture and purify the extracellular vesicles on the membrane. The extracellular vesicles may be washed and collected and utilized in any one of a number of ways including, but not limited to, identifying biomarkers of a disease, identifying the presence of a biomarker in a patient to determine whether a patient has a disease, and therapeutically treating existing diseases by re-introducing the extracellular vesicles, potentially modified, back into a body.

Abstract: A brush motor includes a stator and a rotor. The rotor includes a rotary shaft with a rotor core and commutator fixed thereto. The commutator includes an insulating base and commutator segments fixed to the insulating base. The stator includes 2P stator poles, where P is an integer greater than 1. The rotor comprises m teeth, where 4P>m>2P, and 2m is an integral multiple of P. The rotor includes a rotor winding, which is a concentrated winding having m first elements and m second elements. Each tooth is wound with one of the first elements and one of the second elements. the m first elements form a plurality of element groups, each having n first elements connected in series, and being connected only to corresponding commutator segments at both ends thereof, where P?n?2. Both ends of each second element are connected to corresponding commutator segments.

Abstract: An isolation chip for separating and isolating target particles from a bioliquid sample includes a reagent reservoir, a first filtration membrane, a second filtration membrane, a first chamber, and a second chamber. The reagent reservoir includes a first sidewall and a second sidewall opposite to the first sidewall. The first filtration membrane is disposed at an upper portion of the first sidewall. The reagent reservoir defines a first window at a lower portion of the first sidewall. The second filtration membrane is disposed at the second sidewall. The first chamber is connected to the reagent reservoir through the first filtration membrane. The second chamber is connected to the reagent reservoir through the second filtration membrane. A device and a method for detecting the target particles are further provided.

Abstract: The present invention discloses a multilevel pattern monitoring method for a process industry process and belongs to the fields of industrial production and processing. The multilevel pattern monitoring method comprises the steps: dividing an industry process into a plurality of levels from the view of patterns, selecting a different key performance index for each level, acquiring operating data relevant to the key performance index, identifying the pattern of each level, and proposing a pattern monitoring method for each level based on a data driven method to realize pattern monitoring in the industry process.

Abstract: A system for transmission data protection includes user equipment (UE) and an access point. The access point sends a broadcast message that carries a public key for encryption. The UE receives and stores the public key for encryption. The UE obtains a global public key or a private key corresponding to the UE, and protects transmission data using the public key for encryption and the global public key or the private key corresponding to the UE.

Abstract: Disclosed are a sustained-release injection preparation containing a donepezil derivative in the form of a suspension, and the use of the preparation in the preparation of a medicament for treating diseases caused by abnormal acetylcholinesterase activity.

Abstract: Packaging methods and structures for lateral high voltage gallium nitride (GaN) devices achieve electrical isolation while also maintaining thermal dissipation. The electrical isolation reduces or eliminates vertical leakage current, improving high voltage performance. The packages may use or be compatible standards such as JEDEC, which reduces packaging cost and facilitates implementation of the packaged devices in conventional circuit design approaches.

Abstract: In an AC-DC converter having a primary side control circuit, auxiliary power for the control circuit is derived from the converter secondary side through an isolated DC-DC converter. The circuits and methods solve the problem of supplying primary side auxiliary power during light load or no load operation of the AC-DC power converter. Since the output voltage of the AC-DC converter is normally regulated at a fixed level, the auxiliary voltage that is generated by the isolated DC converter is regulated. In some cases the isolated DC-DC converter may not need to be regulated, which simplifies the design and reduces overall cost.

Abstract: The present application relates to a macrocycle containing aminopyrazole and pyrimidine, which is represented by formula (I), a pharmaceutical composition thereof, and a use thereof in inhibiting tropomyosin receptor kinase (Trk) activity and in treating diseases in mammals that are mediated by Trk.

Abstract: Described are systems and methods that solve localization problems using Machine Learning models to compute country vectors for each linked content item and present content items in response to requests based on the country vectors. For example, a request from a user in Country A may be processed to determine candidate content items responsive to the request and to determine Country A as the country corresponding to the request. The candidate content items may then be processed to determine, for each candidate content item, a country vector corresponding to Country A as indicative of the relevance of the content item to Country A. Content items that are more likely than not to be relevant to the country of the request (e.g., Country A), as indicated by the respective country vector, may be considered as responsive and all other candidate content items discarded.

Abstract: The invention discloses a crystal of 4-(tert-butoxyamino)-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine compound, a mesylate salt and crystal thereof, a preparation method thereof, a composition containing thereof, and a use thereof for inhibiting activity of mutant IDH2 and treating cancer.

Abstract: A field effect transistor includes an exposed channel region disposed between a source region and a drain region. A gate electrode is disposed over the exposed channel region. An electrolyte gel is disposed between the gate electrode and the exposed channel region, wherein ions are immobilized in the electrolyte gel below a transition temperature and mobilized above the transition temperature to increase device resistance.

Abstract: A device (“the ExoTIC device”) for the isolation of extracellular vesicles from an extracellular vesicle-containing sample in which the sample is flowed through a membrane in a flow chamber to capture and purify the extracellular vesicles on the membrane. The extracellular vesicles may be washed and collected and utilized in any one of a number of ways including, but not limited to, identifying biomarkers of a disease, identifying the presence of a biomarker in a patient to determine whether a patient has a disease, and therapeutically treating existing diseases by re-introducing the extracellular vesicles, potentially modified, back into a body.

Abstract: After forming a laterally contacting pair of a semiconductor fin and a conductive strap structure overlying a deep trench capacitor embedded in a substrate and forming a gate stack straddling a body region of the semiconductor fin, source/drain regions are formed in portions the semiconductor fin located on opposite sides of the gate stack by ion implantation. Next, a metal layer is applied over the source/drain region and subsequent annealing consumes entire source/drain regions to provide fully alloyed source/drain regions. A post alloyzation ion implantation is then performed to introduce dopants into the fully alloyed source/drain regions followed by an anneal to segregate the implanted dopants at interfaces between the fully alloyed source/drain regions and the body region of the semiconductor fin.

Abstract: The invention relates to a method and device for predicting a volume median diameter (VIVID) in an overlapped spray area of twin nozzles. Placing a single nozzle at different heights to determine a spray area; measuring all VMDs in the spray area to obtain first true measured values; dividing the first true measured values to construct a first calibration set and a first prediction set; establishing a polynomial fitting formula by a REGRESS function; placing twin nozzles at different heights and different nozzle spacing, and measuring VMDs in the overlapped spray area to obtain second true measured values; determining simulated values of the VMDs of first and second nozzles; dividing the simulated values of the VMDs and the second true measured values to construct a second calibration set and a second prediction set; quantitatively calibrating by using a radial basis function neural network (RBFNN) to obtain a prediction model; determining a VIVID in the overlapped spray area of twin nozzles.

Abstract: A converter includes input voltage terminals, a series circuit connected to the input voltage terminals and including first and second switches connected in series, a transformer including a primary winding and a secondary winding, a resonant tank connected to the series circuit and including the primary winding, an auxiliary switch connected to the series circuit and the resonant tank, output voltage terminals connected to the secondary winding, and a controller that, based on a single control loop and a single control parameter, controls the auxiliary switch with pulse-width modulation and controls the first and second switches with pulse-frequency modulation.

Abstract: A metal-oxide-semiconductor field-effect transistor (MOSFET) device is provided. The device comprising: a substrate; an oxide layer on the substrate; a gate on the oxide layer; a source and a drain on the substrate, wherein the source and the drain are doped with a dopant of a first type; and a cold source coupled to the source, wherein the cold source comprises a junction between a semiconductor doped with a dopant of a second type, and a material selected from the group consisting of metal and semimetal.

Abstract: A casting device of a large non-ferrous metal thin-walled structural component. A liquid outlet of the casting device is communicated with a casting sand box. The casting device comprises an L-shaped liquid storage cylinder, a pressure supplying cylinder, and a crystallization treater. Protective gas with the first gas pressure can be inflated into the top of the L-shaped liquid storage cylinder. The pressure supplying cylinder and the L-shaped liquid storage cylinder are integrally connected to form a U-shaped tube connector. Protective gas with the second gas pressure can be inflated into the top of the pressure supplying cylinder. A liquid inlet of the crystallization treater is communicated with the pressure supplying cylinder while a liquid outlet is communicated with the pouring system and the mold cavity. The crystallization treater is provided with a grain refining mechanism.

Abstract: A multi-stage, multi-level DC-DC step-down converter includes a first stage and a second stage having two identical cells connected in parallel. The first stage includes an input capacitor, four switches, and one flying capacitor. The two cells of the second stage each include four switches and one flying capacitor, and an output filter. The cells of the second stage are driven at half the switching frequency of the input stage, and provides a step-down ratio of 4:1. A third stage having four cells may be added to achieve a step-down ratio of 8:1, a fourth stage having eight cells may be added to achieve a step-down ration of 16:1, etc., each additional stage including a doubling of the number of cells connected in parallel, with all cells being substantially identical, and each stage operating at a further reduced fraction of the switching frequency. Embodiments are particularly suitable for applications such as a 48V intermediate bus architecture for servers and datacenters.