Abstract: A method and an apparatus for controlling a shutoff device, and a shutoff device. The shutoff device includes N main switching transistors and N bypass switching transistors. The method includes: controlling the N main switching transistors to be turned on after receiving a heartbeat signal; determining whether a power supply voltage of a processor is less than a first under-voltage protection voltage; and if so, controlling the N main switching transistors to be turned off, and controlling the N bypass switching transistors to be turned on. Thus, N photovoltaic modules and N main switching transistors corresponding to a shutoff device are separated from multiple photovoltaic module groups, so that the photovoltaic module groups corresponding to other shutoff devices can normally output DC voltage to an inverter, and the inverter can normally output AC power for integration into a power grid, thereby ensuring the normal operation of the photovoltaic system.

Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.

Abstract: The disclosure provides compounds of Formula (I) having the structure: Compounds of Formula (I) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis.

Abstract: A method of performing advertising analytics is provided. The method includes (i) receiving as an input advertising campaign data for a completed advertising campaign, (ii) inputting the received advertising campaign data into a first data processing module which produces extracted root cause dimension combinations, (iii) inputting the output data set into a second data processing module that extracts explainability metrics of the extracted root cause dimension combinations, (iv) inputting the output data set into a third data processing module which creates an output filtered data set, (v) inputting the output filtered data set into a fourth data processing module which maps the root cause dimension combinations to natural language labels, and (vi) embedding the output filtered data set, the explainability metrics of the extracted root cause dimension combinations, and the natural language labels into a natural language template.

Abstract: The disclosure provides a marine plastic floor, which includes a UV layer, a PETG flame-retardant and wear-resistant layer, a PETG color film layer, a PVC middle layer and a PVC bottom layer from top to bottom. According to the technical scheme provided in the disclosure, by optimizing formulations of materials of the middle layer and the bottom layer in the PVC floor, and changing the wear-resistant layer and the color film, after combining them, the PVC floor has sufficient flame retardancy, low smoke and low toxicity after burning, and can meet requirements of MED certification, so that the PVC floor can be used on marine vessels, and vacancy in the current market that there is no PVC floor as the marine floor is filled.

Abstract: Embodiments of the present application relate to substrate comprising a surface-bound azido functionalized organosilane wherein the substrate is free or substantially free of a hydrogel or a hydrophilic polymer. Methods of preparing such substrate surface for sequencing applications are also disclosed.

Abstract: Provided herein are novel anti-CD28 x anti-PSMA antibodies and methods of using such antibodies for the treatment of PSMA-associated cancers. Subject anti-CD28 x anti-PSMA antibodies are capable of agonistically binding to CD28 costimulatory molecules on T cells and PSMA on tumor cells. Thus, such antibodies selectively enhance anti-tumor activity at tumor sites while minimizing peripheral toxicity. The subject antibodies provided herein are particularly useful in combination with other anti-cancer therapies (e.g., anti-CD3 x anti-PSMA antibodies) for the treatment of prostate cancers.

Abstract: The present application discloses a millimeter wave radar detection. An apparatus such as a lavatory or a urinal includes a vitreous body, a water outlet, a sensor, and a control unit. The vitreous body includes a user-facing side opposite to a fixture-facing side. The water outlet is coupled to the user-facing side of the vitreous body. The sensor is coupled to the fixture-facing side of the vitreous body. The control unit is configured to receive sensor data from the microwave radar sensor and generate a command to provide water to the water outlet in response to the sensor data from the microwave radar sensor.

Abstract: Provided herein are immunoconjugates, such as radioimmunoconjugates, comprising a therapeutic moiety conjugated to an antibody or antigen binding domain with binding specificity for hK2. In certain embodiments, the hK2-specific immunoconjugate demonstrates a short half-life. Also provided herein are methods of using the immunoconjugates for selectively targeting cancer cells and for treating diseases such as prostate cancer.

Abstract: A method and an apparatus for controlling a shutoff device, and a shutoff device. The method is applied to a processor of the shutoff device. The method includes: determining whether a heartbeat signal is received continuously during a first preset period; if so, controlling the N main switching transistors to be turned on, and determining whether the heartbeat signal is not received continuously during a second preset period; and if so, controlling the N main switching transistors to be turned off, and controlling the release circuit to be turned on to release a voltage on the bus. A release circuit is controlled to release voltage on the bus to the ground, thereby rapidly reducing the voltage on the bus, avoiding person danger and safety accidents caused by the long-term presence of the direct current high voltage on the bus, and improving the safety and reliability of a photovoltaic system.

Abstract: Provided herein are novel anti-CD28×anti-PSMA antibodies and methods of using such antibodies for the treatment of PSMA-associated cancers. Subject anti-CD28×anti-PSMA antibodies are capable of agonistically binding to CD28 costimulatory molecules on T cells and PSMA on tumor cells. Thus, such antibodies selectively enhance anti-tumor activity at tumor sites while minimizing peripheral toxicity. The subject antibodies provided herein are particularly useful in combination with other anti-cancer therapies (e.g., anti-CD3×anti-PSMA antibodies) for the treatment of prostate cancers.

Abstract: Provided herein are novel anti-CD28× anti-PSMA antibodies and methods of using such antibodies for the treatment of PSMA-associated cancers. Subject anti-CD28× anti-PSMA antibodies are capable of agonistically binding to CD28 costimulatory molecules on T cells and PSMA on tumor cells. Thus, such antibodies selectively enhance anti-tumor activity at tumor sites while minimizing peripheral toxicity. The subject antibodies provided herein are particularly useful in combination with other anti-cancer therapies (e.g., anti-CD3× anti-PSMA antibodies) for the treatment of prostate cancers.

Abstract: A liquid dispenser sensing distance self-learning method includes in response to a self-learning request, entering a self-learning mode. The method also includes, in the self-learning mode, determining a shortest distance between a reference object and a sensing component; determining and storing a sensing distance based on the shortest distance; and identifying, by a first indication device, a state of the self-learning mode. The method also includes, in response to a sensing request, entering a sensing mode; obtaining a detected distance between the reference object and the sensing component; comparing the detected distance with the sensing distance; and identifying, by a second indication device, a comparison result of the detected distance and the sensing distance.

Abstract: An RNA sequencing library preparation process that that utilized transposition with or with a template switch oligonucleotide to generate the libraries having UMIs and spatial barcode information, and methods for improving RNA library preparation from tissue samples using template switching and thermal amplification to improve RNA library quality.

Abstract: A multi-compartment mortar increment container (MIC) enables burning of two propellants to broaden the pressure-time curve providing additional energy and force behind a mortar shell while maintaining allowable pressures. During the ballistic cycle, the mortar increment container burns allowing the faster propellant to mix with the slower propellant. The slower propellant will burn later in the ballistic cycle generating higher pressure behind the projectile leading to higher velocity.

Abstract: In some examples, a hybrid particle for use in capturing a polynucleotide may include a scaffold molecule including a seeding primer and a plurality of first moieties, and a nanoparticle including a plurality of second moieties. The scaffold molecule is coupled to the nanoparticle via interactions between the plurality of first moieties and the plurality of second moieties.

Abstract: Provided herein are immunoconjugates, such as radioimmunoconjugates, comprising a therapeutic moiety conjugated to an antibody or antigen binding domain with binding specificity for hK2. In certain embodiments, the hK2-specific immunoconjugate demonstrates a short half-life. Also provided herein are methods of using the immunoconjugates for selectively targeting cancer cells and for treating diseases such as prostate cancer.

Abstract: A liquid dispenser sensing distance self-learning method includes in response to a self-learning request, entering a self-learning mode. The method also includes, in the self-learning mode, determining a shortest distance between a reference object and a sensing component; determining and storing a sensing distance based on the shortest distance; and identifying, by a first indication device, a state of the self-learning mode. The method also includes, in response to a sensing request, entering a sensing mode; obtaining a detected distance between the reference object and the sensing component; comparing the detected distance with the sensing distance; and identifying, by a second indication device, a comparison result of the detected distance and the sensing distance.

Abstract: In some examples, a method for capturing and amplifying a polynucleotide includes capturing the polynucleotide at a particle comprising a first region and a second region. The first region may include a first moiety that captures the polynucleotide. The second region may include a plurality of amplification primers and have a surface area which is substantially larger than the surface area of the first portion. The method includes using the plurality of amplification primers to amplify the captured polynucleotide.

Abstract: The present disclosure relates to the field of display technology, and provides a display device and a driving method therefor. The driving method includes: providing a display device including a plurality of sub-pixels, each sub-pixel including an OLED light-emitting element, a light-emitting control transistor configured to transmit a driving current to the OLED light-emitting element, and a reset transistor coupled to an anode of the OLED light-emitting element; inputting a periodic cut-off signal to the light-emitting control transistor; determining the effective light-emitting phase of each frame period for the sub-pixel; and during the effective light-emitting phase of each frame period for the sub-pixel, inputting a reset signal to the reset transistor corresponding to one or more cut-off signal.