Abstract: A multi-compartment mortar increment container (MIC) enables burning of two propellants to broaden the pressure-time curve providing additional energy and force behind a mortar shell while maintaining allowable pressures. During the ballistic cycle, the mortar increment container burns allowing the faster propellant to mix with the slower propellant. The slower propellant will burn later in the ballistic cycle generating higher pressure behind the projectile leading to higher velocity.

Abstract: In some examples, a hybrid particle for use in capturing a polynucleotide may include a scaffold molecule including a seeding primer and a plurality of first moieties, and a nanoparticle including a plurality of second moieties. The scaffold molecule is coupled to the nanoparticle via interactions between the plurality of first moieties and the plurality of second moieties.

Abstract: Provided herein are immunoconjugates, such as radioimmunoconjugates, comprising a therapeutic moiety conjugated to an antibody or antigen binding domain with binding specificity for hK2. In certain embodiments, the hK2-specific immunoconjugate demonstrates a short half-life. Also provided herein are methods of using the immunoconjugates for selectively targeting cancer cells and for treating diseases such as prostate cancer.

Abstract: A liquid dispenser sensing distance self-learning method includes in response to a self-learning request, entering a self-learning mode. The method also includes, in the self-learning mode, determining a shortest distance between a reference object and a sensing component; determining and storing a sensing distance based on the shortest distance; and identifying, by a first indication device, a state of the self-learning mode. The method also includes, in response to a sensing request, entering a sensing mode; obtaining a detected distance between the reference object and the sensing component; comparing the detected distance with the sensing distance; and identifying, by a second indication device, a comparison result of the detected distance and the sensing distance.

Abstract: In some examples, a method for capturing and amplifying a polynucleotide includes capturing the polynucleotide at a particle comprising a first region and a second region. The first region may include a first moiety that captures the polynucleotide. The second region may include a plurality of amplification primers and have a surface area which is substantially larger than the surface area of the first portion. The method includes using the plurality of amplification primers to amplify the captured polynucleotide.

Abstract: The present disclosure provides a power adapter including a body and a plug removably connected to the body. In one example, the plug has a second base defining a groove, a housing, and a prong rotatably mounted to the housing. In another example, the body has a tongue extending from a first base, which slides within the groove of the plug to prevent movement of the plug in a first direction. In one example, rotation of the prong actuates a pin held within the plug. For example, the pin recedes into the second base when the prong is in a first position and protrudes from the second base when the prong is in a second position. In one example, the pin prevents movement of the plug in a second direction, different from the first direction, when the prong is in the second position.

Abstract: The present disclosure relates to the field of display technology, and provides a display device and a driving method therefor. The driving method includes: providing a display device including a plurality of sub-pixels, each sub-pixel including an OLED light-emitting element, a light-emitting control transistor configured to transmit a driving current to the OLED light-emitting element, and a reset transistor coupled to an anode of the OLED light-emitting element; inputting a periodic cut-off signal to the light-emitting control transistor; determining the effective light-emitting phase of each frame period for the sub-pixel; and during the effective light-emitting phase of each frame period for the sub-pixel, inputting a reset signal to the reset transistor corresponding to one or more cut-off signal.

Abstract: An interchangeable touchless faucet system for use with interchangeable spouts and related methods of replacing interchangeable faucets. The interchangeable faucet design generally includes coupling variations of a spout, which may be readily attached and detached to a sensor puck. Fluid is delivered through the sensor puck and through one of the interchangeable spouts from a mixer valve coupled to hot and cold waterlines, where the fluid is dispensed into a basin, sink, tub, etc. when a sensor integrated with the sensor puck is activated by a user, such as by waving one's hand near the sensor.

Abstract: The disclosure provides compounds of formula (II) having the structure: Compounds of formula (II) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis.

Abstract: The disclosure provides compounds of formula (II) having the structure: Compounds of formula (II) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis.

Abstract: An automated machining system comprising a CNC machine and a processor configured to automatically identify one or more features to be machined into a workpiece to form a part; determine a set of tools suitable for performing a removal operation associated with machining each feature; identify those tools necessary for performing roughing and finishing removal operations for each feature; generate various sequences of removal operations suitable for machining all of the one or more features; calculate a cost of performing each removal operation sequence; determine which of the removal operations sequences is optimal; generate corresponding toolpaths for machining the features into the workpiece; and provide instructions to the CNC machine for automatically implementing the optimal removal operation sequence and corresponding toolpaths to machine the features into the workpiece to form the part. A system for automatic generation and optimization of machining strategies.

Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a human Kallikrein-2 (hK2), and immunoresponsive cells comprising such CARs, for the treatment of cancer.

Abstract: The present disclosure is directed to decoupling library capture (template seeding) from cluster generation to optimise both processes. This is achieved by introducing orthogonality between the seeding and clustering primer.

Abstract: A method and an apparatus for controlling a shutoff device, and a shutoff device. The shutoff device includes N main switching transistors and N bypass switching transistors. The method includes: controlling the N main switching transistors to be turned on after receiving a heartbeat signal; determining whether a power supply voltage of a processor is less than a first under-voltage protection voltage; and if so, controlling the N main switching transistors to be turned off, and controlling the N bypass switching transistors to be turned on. Thus, N photovoltaic modules and N main switching transistors corresponding to a shutoff device are separated from multiple photovoltaic module groups, so that the photovoltaic module groups corresponding to other shutoff devices can normally output DC voltage to an inverter, and the inverter can normally output AC power for integration into a power grid, thereby ensuring the normal operation of the photovoltaic system.

Abstract: A method and an apparatus for controlling a shutoff device, and a shutoff device. The method is applied to a processor of the shutoff device. The method includes: determining whether a heartbeat signal is received continuously during a first preset period; if so, controlling the N main switching transistors to be turned on, and determining whether the heartbeat signal is not received continuously during a second preset period; and if so, controlling the N main switching transistors to be turned off, and controlling the release circuit to be turned on to release a voltage on the bus. A release circuit is controlled to release voltage on the bus to the ground, thereby rapidly reducing the voltage on the bus, avoiding person danger and safety accidents caused by the long-term presence of the direct current high voltage on the bus, and improving the safety and reliability of a photovoltaic system.

Abstract: Provided herein are novel anti-CD28 x anti-PSMA antibodies and methods of using such antibodies for the treatment of PSMA-associated cancers. Subject anti-CD28 x anti-PSMA antibodies are capable of agonistically binding to CD28 costimulatory molecules on T cells and PSMA on tumor cells. Thus, such antibodies selectively enhance anti-tumor activity at tumor sites while minimizing peripheral toxicity. The subject antibodies provided herein are particularly useful in combination with other anti-cancer therapies (e.g., anti-CD3 x anti-PSMA antibodies) for the treatment of prostate cancers.

Abstract: Methods for on-flow cell selective capture and enrichment of clustered beads, general capture strategies on bead mobility on flow cell surfaces, sorting clustered and unclustered beads, and flow cell reusability for bead immobilization onto flow cells.

Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.

Abstract: A PCIe controller and a loopback path using the PCIe controller. The PCIe controller includes: a transport layer transmission module, a transport layer reception module, a memory access module, and a memory, wherein the transport layer transmission module includes a first loopback control module, the transport layer reception module includes a second loopback control module, and the first loopback control module is coupled to the second loopback control module; the memory access module is coupled to the transport layer transmission module and the transport layer reception module, and the memory access module is also coupled to the memory.