Abstract: Provided herein are immunoconjugates, such as radioimmunoconjugates, comprising a therapeutic moiety conjugated to an antibody or antigen binding domain with binding specificity for hK2. In certain embodiments, the hK2-specific immunoconjugate demonstrates a short half-life. Also provided herein are methods of using the immunoconjugates for selectively targeting cancer cells and for treating diseases such as prostate cancer.

Abstract: A liquid dispenser sensing distance self-learning method includes in response to a self-learning request, entering a self-learning mode. The method also includes, in the self-learning mode, determining a shortest distance between a reference object and a sensing component; determining and storing a sensing distance based on the shortest distance; and identifying, by a first indication device, a state of the self-learning mode. The method also includes, in response to a sensing request, entering a sensing mode; obtaining a detected distance between the reference object and the sensing component; comparing the detected distance with the sensing distance; and identifying, by a second indication device, a comparison result of the detected distance and the sensing distance.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for speech synthesis. The methods, systems, and apparatus include actions of obtaining an audio representation of speech of a target speaker, obtaining input text for which speech is to be synthesized in a voice of the target speaker, generating a speaker vector by providing the audio representation to a speaker encoder engine that is trained to distinguish speakers from one another, generating an audio representation of the input text spoken in the voice of the target speaker by providing the input text and the speaker vector to a spectrogram generation engine that is trained using voices of reference speakers to generate audio representations, and providing the audio representation of the input text spoken in the voice of the target speaker for output.

Abstract: The present disclosure provides a comic image generation method and apparatus, a computer device, and a storage medium, and the method includes: acquiring pose text information corresponding to a comic storyboard, the pose text information being used for describing target action poses of at least one target object; determining a pose assistance image corresponding to the comic storyboard according to the pose text information, reference action poses of a reference object in the pose assistance image matching the target action poses; and generating comic images corresponding to the comic storyboard using an artificial intelligence model according to the pose text information and the pose assistance image, target objects in the comic images having the target action poses.

Abstract: Provided are a vehicle control method and apparatus, a device, and a storage medium. The vehicle control method includes: acquiring positioning data output by a GNSS module and IMU data output by an IMU module, and acquiring attitude angle data based on the positioning data and the IMU data; acquiring rotation angle information of a vehicle front wheel based on the IMU data, motor position encoder data of an electric steering wheel, and vehicle size data; acquiring target rotation angle information of the vehicle front wheel based on the positioning data, the attitude angle data, the vehicle size data, the rotation angle information of the vehicle front wheel, and planned path data; generating target control information based on the target rotation angle information, and sending the target control information to the electric steering wheel so that the electric steering wheel rotates based on the target control information.

Abstract: Disclosed in the present application is a hybrid automatic repeat request feedback method, which comprises the steps that: an HARQ-ACK codebook includes HARQ-ACK information of M PDSCHs, the M PDSCHs are all scheduled by first-type PDCCHs, and the first-type PDCCHs are used for activating an SPS configuration; the order of the HARQ-ACK information of the M PDSCHs in the HARQ-ACK codebook is arranged according to at least one parameter value among cell indexes, BWP indexes, SPS configuration indexes and PDSCH transmission moments of the M PDSCHs. The embodiments of the present application also provide a hybrid automatic repeat request feedback method with the participation of second-type PDCCHs for releasing SPS and dynamically configured third-type PDCCHs. The present application also provides a terminal device and a network device to which the method is applied. The present application solves the problem of how to generate an HARQ-ACK codebook when there are multiple PDSCHs in an SPS configuration condition.

Abstract: A fin field-effect transistor device with hybrid conduction mechanism, including a fin field-effect transistor, a second source region, and a second drain region; the fin field-effect transistor includes a substrate, a fin channel region, a first source region, and a first drain region; the height of the second source region is not lower than the height of the substrate between the first source region and the first drain region; the first source region, the first drain region and the second drain region are doped with first ions; the second source region is formed between the substrate and the first source region, the second drain region is formed between the substrate and the first drain region, the second source region is doped with second ions. This scheme can realize hybrid conduction of fin channel diffusion drift current and bottom channel band-to-band tunneling current, thus obtaining better ultra-steep switching characteristics.

Abstract: A method for aligning a laser point cloud and an image based on deep learning includes: collecting data by using a laser ladar and a camera, to obtain laser point cloud data and a two-dimensional (2D) image respectively; dividing preprocessed point cloud data into triangular meshes to obtain a three-dimensional (3D) mesh model of the point cloud data; determining a relative location relationship between a laser radar and the multi-function camera, and constructing a virtual camera in the 3D mesh model to capture a simulated 2D image at a same location and angle as those of the camera; and aligning, by using a convolution neural network (CNN), the 2D image captured by the camera and the simulated 2D image captured by the virtual camera to generate aligned images that map onto each other.

Abstract: A method for processing fused “underground+ground” data in deep formation exploration includes: collecting underground multi-source data by an underground intelligent probing rod, preprocessing the multi-source data to obtain an original digital signal, storing the original digital signal in an underground memory, obtaining continuous depth data by a ground device; performing high-bitrate and low-bitrate compression on the original digital signal, and modulating compressed signals; driving modulated signals by power, so the modulated signal is transmitted in a drilling stem with cable in a form of a power line carrier and then output, or first transmitted in a first section of the drilling stem with cable, re-collected in a short drill pipe with repeater, re-emitted to a second section of the drilling stem with cable, and then output; when a transmission line is disconnected, synchronizing and fusing data; and finally using fused data and the data output by the transmission line as final output data.

Abstract: In some examples, a method for capturing and amplifying a polynucleotide includes capturing the polynucleotide at a particle comprising a first region and a second region. The first region may include a first moiety that captures the polynucleotide. The second region may include a plurality of amplification primers and have a surface area which is substantially larger than the surface area of the first portion. The method includes using the plurality of amplification primers to amplify the captured polynucleotide.

Abstract: The present disclosure provides a power adapter including a body and a plug removably connected to the body. In one example, the plug has a second base defining a groove, a housing, and a prong rotatably mounted to the housing. In another example, the body has a tongue extending from a first base, which slides within the groove of the plug to prevent movement of the plug in a first direction. In one example, rotation of the prong actuates a pin held within the plug. For example, the pin recedes into the second base when the prong is in a first position and protrudes from the second base when the prong is in a second position. In one example, the pin prevents movement of the plug in a second direction, different from the first direction, when the prong is in the second position.

Abstract: The present disclosure relates to the field of display technology, and provides a display device and a driving method therefor. The driving method includes: providing a display device including a plurality of sub-pixels, each sub-pixel including an OLED light-emitting element, a light-emitting control transistor configured to transmit a driving current to the OLED light-emitting element, and a reset transistor coupled to an anode of the OLED light-emitting element; inputting a periodic cut-off signal to the light-emitting control transistor; determining the effective light-emitting phase of each frame period for the sub-pixel; and during the effective light-emitting phase of each frame period for the sub-pixel, inputting a reset signal to the reset transistor corresponding to one or more cut-off signal.

Abstract: An interchangeable touchless faucet system for use with interchangeable spouts and related methods of replacing interchangeable faucets. The interchangeable faucet design generally includes coupling variations of a spout, which may be readily attached and detached to a sensor puck. Fluid is delivered through the sensor puck and through one of the interchangeable spouts from a mixer valve coupled to hot and cold waterlines, where the fluid is dispensed into a basin, sink, tub, etc. when a sensor integrated with the sensor puck is activated by a user, such as by waving one's hand near the sensor.

Abstract: The disclosure provides compounds of formula (II) having the structure: Compounds of formula (II) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis.

Abstract: The disclosure provides compounds of formula (II) having the structure: Compounds of formula (II) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis.

Abstract: An automated machining system comprising a CNC machine and a processor configured to automatically identify one or more features to be machined into a workpiece to form a part; determine a set of tools suitable for performing a removal operation associated with machining each feature; identify those tools necessary for performing roughing and finishing removal operations for each feature; generate various sequences of removal operations suitable for machining all of the one or more features; calculate a cost of performing each removal operation sequence; determine which of the removal operations sequences is optimal; generate corresponding toolpaths for machining the features into the workpiece; and provide instructions to the CNC machine for automatically implementing the optimal removal operation sequence and corresponding toolpaths to machine the features into the workpiece to form the part. A system for automatic generation and optimization of machining strategies.

Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.

Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a human Kallikrein-2 (hK2), and immunoresponsive cells comprising such CARs, for the treatment of cancer.

Abstract: The present disclosure is directed to decoupling library capture (template seeding) from cluster generation to optimise both processes. This is achieved by introducing orthogonality between the seeding and clustering primer.

Abstract: A method and an apparatus for controlling a shutoff device, and a shutoff device. The method is applied to a processor of the shutoff device. The method includes: determining whether a heartbeat signal is received continuously during a first preset period; if so, controlling the N main switching transistors to be turned on, and determining whether the heartbeat signal is not received continuously during a second preset period; and if so, controlling the N main switching transistors to be turned off, and controlling the release circuit to be turned on to release a voltage on the bus. A release circuit is controlled to release voltage on the bus to the ground, thereby rapidly reducing the voltage on the bus, avoiding person danger and safety accidents caused by the long-term presence of the direct current high voltage on the bus, and improving the safety and reliability of a photovoltaic system.