Abstract: An optical encoder. The encoder includes a coding element, an emitter, and a detector. The coding element has a track with a track pattern. The track pattern includes a plurality of optically distinguishable sections, which include a plurality of position sections and an index section. The emitter generates a light signal incident on the track of the coding element. The detector includes a combined position and index photodetector array. The combined position and index photodetector array includes a plurality of position photodetectors and an index photodetector. Embodiments of this type of optical encoder implement position and index sections in a single track on the coding element.

Abstract: A user navigational apparatus. The user navigational apparatus includes a dial, a coding element, and an encoder. The coding element is coupled to a dial. The coding element includes a track of alternating reflective and non-reflective sections, each having a substantially oblique leading edge relative to a direction of movement of the coding element. The encoder includes an emitter and a detector. The emitter generates a light signal incident on the track of the coding element. The detector detects a reflected light signal which corresponds to a portion of the incident light signal that is reflected off of the reflective sections of the track. The detector also generates a channel signal corresponding to the reflected light signal.

Abstract: A user navigational apparatus. The user navigational apparatus includes a code wheel and an encoder. The code wheel is coupled to a dial. The code wheel includes a track of alternating reflective and non-reflective sections. The optical reflective encoder includes an emitter and a detector. The emitter generates a light signal incident on the track of the code wheel. The detector detects a reflected light signal. The reflected light signal corresponds to a portion of the incident light signal that is reflected off of the reflective sections of the track. The detector also generates a channel signal corresponding to the reflected light signal. Embodiments of this type of user navigational apparatus achieve reduced thickness compared to conventional implementations of jog wheels.

Abstract: A system includes a well tool for deployment in a well, a controller, and a link coupled between the controller and the well tool. The well tool comprises plural control units, each of the plural control units having a microprocessor and an initiator coupled to the microprocessor. Each microprocessor is adapted to communicate bi-directionally with the controller. The controller is adapted to send a plurality of activation commands to respective microprocessors to activate the respective control units. Each activation command containing a unique identifier corresponding to a respective control unit.

Abstract: An optical encoder includes an emitter, a first lens, a detector, a second lens, and a protrusion. The emitter emits light which is directed by the first lens to a code scale for reflection. The reflected light is directed by the second lens to the detector. The detector detects the reflected light from the code scale. The protrusion is between the first lens and the second lens. The protrusion defines at least one surface that refracts stray light from the emitter away from the detector. Accordingly, the stray light does not reach the detector; thus the detector can operate more effectively.

Abstract: An hemoglobin (Hb)-Dextran (Dx) conjugate having a molecular weight between 50 kd and 500 kD provides a blood substitute that results in acceptable erythrocyte sedimentation rate (ESR) and excretion rate (EXC) values. DxHb conjugates of the invention can be used for a variety of purposes as an alternative to blood.

Abstract: A lead frame (10) for a semiconductor device includes a first row of terminals (12) surrounding a die receiving area (14) and a second row of terminals (16) spaced from and surrounding the first row of terminals (12). The first and second rows of terminals (12, 16) have a first height (H1). The terminals (12) of the first row include a step (26) that has a greater height (H2). Bond wires (36) connecting die pads (34) to the first row terminals (12) extend over the second height H2 part of the terminal (12) and are attached to the first height H1 part of the terminal (12). The step (26) insures that the bond wires (36) attached to the stepped terminals (12) have a high wire kink profile so that they are less susceptible to damage in later process steps.

Abstract: An optical encoder includes a code strip having a first side, a second side, a first track comprising indicia thereon, and a second track comprising indicia thereon. The code strip is moveable along a displacement path with respect to the optical encoder. A light source positioned on the first side of the code strip directs light toward the code strip. A first detector element is positioned on the second side of the code strip and is generally aligned with the first track of the code strip. A second detector element is positioned on the second side of the code strip and is generally aligned with the second track of the code strip. The second detector element is also positioned so that the second detector element is located a spaced distance along the displacement path from the first detector element.

Abstract: An Enhanced Reflective Optical Encoder (“EROE”) having an emitter module for transmitting emitted optical radiation to an encoded media and a detector module for receiving reflected optical radiation from the encoded media. The EROE may include a transmissive layer covering both the emitter module and the detector module, and an optical isolation element located within the transmissive layer and located between the emitter module and the detector module. The optical isolation element reduces undesired optical radiation transmitted from the emitter module to the detector module, where the undesired optical radiation is a portion of the emitted optical radiation.

Abstract: An electronic device (60) including a first integrated circuit (IC) die (62) electrically connected to a first lead frame (64) and a second IC die (66) electrically connected to a second lead frame (68). The first lead frame (64) is electrically connected to the second lead frame (68) by at least one stud bump (72), which is selectively formed where an electrical connection between the first lead frame (64) and the second lead frame (68) is required. The first and second lead frames (64) and (68), the first and second IC dies (62) and (66), and the at least one stud bump (72) are encapsulated by a mold compound (74) to form a 3D package.

Abstract: A lead frame panel (40) includes a body (42) having an array of die support areas (44) for receiving respective semiconductor dies. The die support areas (44) are surrounded by leads (46). Adjacent rows of leads are coupled by half-etched connection bars (48), such that each half-etched portion of the connection bars (48) forms a channel into which a mold compound (54) is injected.

Abstract: An isolation apparatus is provided between an electrical conductor and an electrically-activated well tool. The isolation apparatus has a blocking element to enable a signal having a first electrical polarity to pass through the element. The blocking element blocks a signal having a second electrical polarity.

Abstract: The invention provides compositions containing an effective amount of a therapeutic agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-?1. This invention further provides methods for the targeted delivery of a therapeutic agent to a tissue expressing asialoglycoprotein receptors by delivery to the tissue an effective amount of a composition containing an effective amount of the agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-?1. Also provided by this invention is a method for inhibiting the proliferation of liver cancer by administering to a subject in need of such therapy an effective amount of a composition containing doxorubicin encapsulated in desialyated glycoprotein-?1 coupled to a liposome.

Abstract: A method of genotyping single nucleotide polymorphisms (“SNP”) and point mutations in nucleic acid based on chain extension by polymerase. This invention is based on the fact that the nucleoside immediately 5? adjacent to any SNP/point mutation site is known, and the neighboring sequence immediately 3? adjacent to the site is also known. A primer complementary to the sequence directly adjacent to the SNP on the 3? side in a target polynucleotide is used for chain elongation. The polymerase reaction mixture contains one chain-terminating nucleotide having a base complementary to the nucleotide directly adjacent to the SNP on the 5? side in the target polynucleotide. An additional dNTP may be added to produce a primer with the maximum of a two-base extension. The resultant elongation/termination reaction products are analyzed for the length of chain extension of the primer, or for the amount of label incorporation from a labeled form of the terminator nucleotide.

Abstract: An isolation apparatus is provided between an electrical conductor and an electrically-activated well tool. The isolation apparatus has a blocking element to enable a signal having a first electrical polarity to pass through the element. The blocking element blocks a signal having a second electrical polarity.

Abstract: An hemoglobin (Hb)-Dextran (Dx) conjugate having a molecular weight between 50 kD and 500 kD provides a blood substitute that results in acceptable erythrocyte sedimentation rate (ESR) and excretion rate (EXC) values. DxHb conjugates of the invention can be used for a variety of purposes as an alternative to blood.

Abstract: A method of genotyping single nucleotide polymorphisms (“SNP”) and point mutations in nucleic acid based on chain extension by polymerase. This invention is based on the fact that the nucleoside immediately 5′ adjacent to any SNP/point mutation site is known, and the neighboring sequence immediately 3′ adjacent to the site is also known. A primer complementary to the sequence directly adjacent to the SNP on the 3′ side in a target polynucleotide is used for chain elongation. The polymerase reaction mixture contains one chain-terminating nucleotide having a base complementary to the nucleotide directly adjacent to the SNP on the 5′ side in the target polynucleotide. An additional dNTP may be added to produce a primer with the maximum of a two-base extension. The resultant elongation/termination reaction products are analyzed for the length of chain extension of the primer, or for the amount of label incorporation from a labeled form of the terminator nucleotide.

Abstract: The invention provides compositions containing an effective amount of a therapeutic agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-&agr;1. This invention further provides methods for the targeted delivery of a therapeutic agent to a tissue expressing asialoglycoprotein receptors by delivery to the tissue an effective amount of a composition containing an effective amount of the agent encapsulated in a liposome coupled to a desialyated glycoprotein, e.g., desialyated glycoprotein-&agr;1. Also provided by this invention is a method for inhibiting the proliferation of liver cancer by administering to a subject in need of such therapy an effective amount of a composition containing doxorubicin encapsulated in desialyated glycoprotein-&agr;1 coupled to a liposome.

Abstract: A blood substitute or blood extender is prepared by chemically coupling hemoglobin with a polysaccharide material selected from dextran and hydroxyethyl starch, and having a molecular weight of from about 5,000 to about 2,000,000, to form a covalently bonded chemical complex. The complex has similar oxygen transporting abilities to hemoglobin, and has a much lower rate of renal excretion.