Abstract: The present disclosure provides a thin film transistor, a method for manufacturing the thin film transistor, an array substrate and a display panel. The thin film transistor includes: a substrate; and a gate electrode, a gate insulating layer, an active layer, a source electrode and a drain electrode on the substrate, wherein the active layer includes a first semiconductor layer and a second semiconductor layer sequentially arranged in a direction perpendicular to the substrate, the second semiconductor layer is arranged on a side of the first semiconductor layer away from the gate electrode; an absolute value of a difference between conduction band minimums of a first oxide material and a second oxide material is greater than 0.2 eV.

Abstract: Provided are a thin film transistor, a display substrate and a display device, the thin film transistor includes: a gate on a base substrate; an active layer between the gate and the base substrate, the active layer includes a source contact portion, a drain contact portion and a middle portion therebetween, orthographic projections of the middle portion and the gate on the base substrate overlaps to form a first overlapping region, a material of the middle portion includes a metal oxide containing a doped element, a dissociation energy of the doped element from an oxygen element is greater than 500 Kj/mol; a source connected to the source contact portion and a drain connected to the drain contact portion, a ratio of an area of the orthographic projection of the gate on the base substrate to an area of the first overlapping region is less than or equal to 3.

Abstract: Provided is a micro-nano fluidic substrate, a chip, a preparation method, and a system. The micro-nano fluidic substrate includes: a base; an electrode layer located on the base, the electrode layer includes a first electrode, a second electrode, and a control electrode; and a film layer located on the electrode layer and far away from the base, the film layer includes a groove layer, a nano-channel and a micro-channel, the groove layer includes a first groove, the nano-channel is located in the first groove, an orthographic projection of the nano-channel on the base at least partially coincides with an orthographic projection of the control electrode on the base, and the micro-channel is in communication with the nano-channel, the micro-channel includes a first micro-channel and a second micro-channel, and the first micro-channel is in communication with the first electrode, the second micro-channel is in communication with the second electrode.

Abstract: Embodiments of this application provide a database task processing method, a hot and cold data processing method, a storage engine, a device, and a storage medium. In the embodiments of this application, a database storage engine is integrated with a machine learning model, involved data samples and used resources in training of the machine learning model are dynamically adjusted by sensing a load pressure of the database storage engine, and through data collection at a storage engine level and a design of a lightweight model, online updating is performed on a model based on a background task. In this way, effectiveness and availability that the database storage engine is integrated with the machine learning model are ensured, and an accuracy rate and a recall rate of a task execution result are improved.

Abstract: A wiring board includes a base substrate and first connection pads disposed on the base substrate. The first connection pads each include electrical connection layer(s); each electrical connection layer includes a main material layer and protective layer(s) disposed on a side of the main material layer away from the base substrate; the protective layer(s) include a first reference protective layer, which is a protective layer farthest away from the base substrate in the protective layer(s); and a material of the main material layer includes copper. The electrical connection layer(s) includes a first electrical connection layer, which is an electrical connection layer farthest away from the base substrate in the electrical connection layer(s); and in protective layer(s) in the first electrical connection layer, at least a material of the first reference protective layer is capable of forming a first intermetallic compound with a first solder.

Abstract: The present disclosure provides a TFT, a manufacturing method and a display substrate, and it relates to the field of TFT technology. The TFT includes: a base substrate; a gate electrode arranged on the base substrate; an active layer arranged at a side of the gate electrode away from the base substrate, an orthogonal projection of the active layer onto the base substrate overlapping with an orthogonal projection of the gate electrode onto the base substrate; and a source electrode and a drain electrode arranged at a side of the active layer away from the base substrate and coupled to the active layer. A resistance between the gate electrode and the drain electrode is greater than a resistance between the gate electrode and the source electrode. According to the present disclosure, it is able to increase a withstand voltage range of the TFT.

Abstract: A wiring board includes a substrate, conductive pads and at least one protective layer group. The conductive pads are disposed on the substrate. The at least one protective layer group is disposed on a side of the conductive pads away from the substrate; a protective layer group includes an oxidation protective layer and a palladium alloy layer that are stacked, and the oxidation protective layer is closer to the substrate than the palladium alloy layer. A material of the oxidation protective layer includes a nickel-based alloy.

Abstract: Provided are a thin-film transistor and a manufacturing method thereof, and a display substrate, belonging to the technical field of thin-film transistors. The thin-film transistor includes: a base substrate; a gate electrode on the base substrate; an active layer on a side of the gate electrode away from the base substrate, an orthographic projection of the active layer onto the base substrate overlapping with an orthographic projection of the gate electrode onto the base substrate; and a first electrode and a second electrode on a side of the active layer away from the base substrate, the first electrode being one of a source electrode and a drain electrode, and the second electrode being the other of the source electrode and the drain electrode.

Abstract: Provided is a display substrate including a substrate and a plurality of light emitting units and a plurality of light detection units located on the substrate, At least one light emitting unit includes a light emitting element and a pixel circuit connected to the light emitting element, and at least one light detection unit includes an optical sensing element and a light emitting detecting circuit connected to the optical sensing element. At least one inorganic hydrogen barrier layer is arranged on one side of the optical sensing element close to the substrate. The light emitting element has a first light emitting region and a second light emitting region, the first light emitting region of the light emitting element emits light from a side away from the substrate, and the second light emitting region of the light emitting element emits light from a side close to the substrate.

Abstract: Embodiments of the present disclosure provide an array substrate and a display apparatus. The array substrate includes: a base substrate; a conductive layer located on the base substrate, where a material of the conductive layer includes copper; and an oxidization protective layer, located on a side, facing away from the base substrate, of the conductive layer, where a material of the oxidization protective layer includes tungsten.

Abstract: Disclosed are a derivative of a 2,5-diketopiperazine compound, and a preparation method therefor, a pharmaceutical composition thereof and the use thereof. Specifically, disclosed are a compound as represented by formula (I), a stereoisomer thereof, a tautomer thereof or a pharmaceutically acceptable salt thereof, or a solvate of any one of the aforementioned. The compound is new in terms of structure, and has good anti-tumor activity and water solubility.

Abstract: The present invention relates to a nanoparticulate composition comprising nanoparticles formed from an amphipathic block copolymer comprising a hydrophilic block and a hydrophobic block, where the nanoparticles are provided in the form of micelles, cylindrical worm structures or vesicles and the size of the nanoparticles is from 25 to 500 nm, wherein: the composition is substantially free of heavy metals and compounds comprising sulfur. Also disclosed herein is a method of forming said nanoparticulate composition by polymerization induced self-assembly (PISA) via non-transition-metal catalysed controlled radical polymerization (NTMC-CRP).

Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.

Abstract: The present invention provides a class of novel NAMPT enzyme agonist and preparation and use thereof, which has a structural formula as shown in formula I or formula II. The present invention screens the NAMPT agonist NAT from the chemical small molecule library, and the NAT exhibits a good cytoprotective effect and a good anti-neurodegeneration effect in animal models of neurodegeneration. We studied the binding of NAT to enzymes, and then carried out multiple rounds of structure optimization based on the chemical structure characteristics of NAT and its enzyme activity properties, and obtained a relatively defined structure-activity relationship. The present patent not only lays the foundation for developing innovative drugs for anti-aging and neurodegenerative diseases, but also theoretically provides a proof-of-concept that enhancing NAMPT enzyme activity plays an important role in neuroprotection.

Abstract: Provided are a method for maintaining Walker constellation formation and a terminal device. The method comprises: determining a first offset amount of each satellite within a simulation time period according to parameters of a Walker constellation; performing first offset on each satellite according to the first offset amount to obtain a Walker constellation after the first offset; determining a second offset amount of each satellite within the simulation time period according to parameters of the Walker constellation after the first offset; and superimposing the first offset amount and the second offset amount, and performing second offset on each satellite so as to maintain the formation of the Walker constellation.

Abstract: A data migration method and apparatus, a device, a distributed system and a storage medium are provided. Said method is applied to each data node in a distributed system comprising a plurality of data nodes. Said method comprises: determining, in a current data migration task, a table to be migrated of a current node, and a target data node (S101); and writing incremental data in the table to be migrated into the table to be migrated, and a target data table of the target data node, the incremental data being data obtained by performing, after the data migration task is started, a change operation on data in the table to be migrated (S102).

Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.

Abstract: A twistable and stackable shelf includes storage members, an elastic member, a first supporting pipe, a second supporting pipe, a first connecting member, and a second connecting member. Each of the first and second connecting member includes an end portion defining an inserting hole and an inserting portion defining a bottom groove and fluidly connected to the inserting hole. Two ends of the elastic member are inserted into the inserting holes and extend to the bottom grooves; two hooking members are arranged in the bottom grooves. The first and second supporting pipes form a vertical arrangement through the first and second connecting members and support the plurality of the storage members in a vertical direction. Or, the first and second supporting pipes form a horizontal arrangement through the first and second connecting members, and the storage members are twisted and stacked in the vertical direction.

Abstract: Embodiments in the present description provide an operation request processing method and apparatus, and a device, and a readable storage medium, and a system. In the present embodiment, after obtaining an operation request for a data table, a read-write node can return a request processing completion message to a requester in time without waiting for all read-only nodes; a locking operation is performed on the data table, a log of locking the data table is written into a redo log file; and after status information of the log of locking is written into a status record, a monitoring processing process can achieve log playback monitoring of all the read-only nodes by using the status record and the log of locking. Thus, an asynchronous processing mechanism is achieved, and the stability and efficiency of operation request execution are improved.