Abstract: Disclosed is a pyridazinone compound represented by Formula (I), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, stereoisomer, or isotopic variant thereof. The compound can be used for preparation of medicinal products for treatment and/or prophylaxis of a disease or condition associated with thyroid hormone abnormalities. The compound has higher selectivity to TH?, better pharmacokinetic parameters, desired stability, and higher agonistic activity toward TH?.

Abstract: Disclosed are a temporary plugging agent and a preparation method thereof, and a method for temporary plugging and fracturing of a high-temperature reservoir. The temporary plugging agent includes the following components in mass fractions: acrylamide 5%, composite crosslinking agent 1%, laponite 1%, ammonium persulfate 0.1% and water 92.9%.

Abstract: An adaptive characteristic spectral line screening method and system based on atomic emission spectrum are provided, the method includes: using a set characteristic screening optimization method to perform a plurality of optimization rounds of characteristic screening, obtaining an initialized spectral dataset of each round of the characteristic screening and initialized characteristic population genes; obtaining an optimal characteristic population gene of each round by a set analysis method, a fitness function, and an iteration of a genetic algorithm; obtaining an optimized characteristic spectral information set when the plurality of optimization rounds reach set optimization rounds; performing combination statistics and discriminant analyses on the optimized characteristic spectral information set to complete an adaptive characteristic spectral line screening.

Abstract: Multifunctional coatings and chemical additives, comprising of lubricant, micro/nano-textured particles, emulsifiers, hydrogel polymers, cross-linking agent to modify the hydrogel polymers, antimicrobial to preserve the bio-based materials, and water solvent, are useful in hydraulic fracturing operation either directly applied on the surface of proppants, or/and mixed with other friction reducer additives to totally or partially substitute the regular friction reducer chemicals, alternatively, as additive components blended or mixed into regular fracturing fluid for easily pumping proppants downhole and stabilizing the pumping pressure; beneficial to the well productivity, effectively suppress and mitigate the risk of respirable microcrystalline dust as the coated materials are transported and handled in the manufacturing plant, terminal, and oil application fields without a need for drying operation on the coating products.

Abstract: An elastic object rendering method and apparatus, a device, and a storage medium are provided. The method comprises: constructing a grid model of an elastic object in response to a deformation trigger operation for the elastic object, first determining the deformation position and speed of an acted point in the grid model of the elastic object under the deformation trigger operation; determining the motion trajectory of each grid point in the grid model of the elastic object according to the deformation position and speed of the acted point, and the elastic constraint of each grid point in the grid model of the elastic object; and finally, according to the motion trajectory of each grid point in the grid model of the elastic object, invoking the grid model of the elastic object to perform elastic motion.

Abstract: Bioinspired chemical additives, coating, and chemical solution useful for enhancing the strength of self-healing hydraulic-cement concrete, comprising of micro/nano/textured dual phobic dot domains, hydrogel polymer, water, mineral oil, and surfactants assembled into micelle emulsion, mixed with cement, water, sand, and aggregates by weight percentage at a mix ratio of from 0.00001/99.9999 to 10.0/90, of which the ratio of water to cement from 0.10 to 0.80 (W/C), the volume fraction of cement for total volume of concrete from 5 to 50%, sand 40% to 90%, and aggregate 40% to 90%, a replacement of cement with cementitious materials from 0.

Abstract: Bioinspired chemical additives, coating, or/and solution, in mimicking biomineralization processes of bone, useful for enhancing the strength of hydraulic-cement concrete and mitigating the risk of its cracking failure, comprising of micro/nano/textured dual phobic dot domains as core layer, hydrogel polymer as shell, prepared by water and mineral oil as solvent via surfactant/emulsifier as intermediate layer encapsulated in an emulsion, were mixed with cement, fine sand, and aggregates by weight percentage at a mix ratio of from 0.00001/99.99999 to 10.0/90, of which the ratio of water to cement is ranged from 0.2 to 0.80 (W/C), the volume fraction of cement accounted for total volume fraction of solid from 5 to 50%, the fine sand from 40% to 90%, and aggregate from 40% to 90% as water dried, a replacement of cement with cementitious materials such as microcrystalline silica sand, micro gel, and swollen clays ranged from 0.

Abstract: Chemical additives useful for hydraulic fracturing operation are comprising of lubricant/nonpolar solvents; hydro-dual-phobic domains as core encapsulated by emulsifiers as shell, suspended in water by hydrogel polymers as hydrophilic domains; soy protein isolate (SPI) and sweet rice flour were modified with crosslinking polymers of isocyanate as hydrophobic domains, which is incorporated into the frac fluid as a standard alone friction reducer solution or as an enhancer of frac fluid viscosity of the final frac fluid products in high salinity brines having a concentration as high as 25.0% at an ambient temperature at a downhole well temperature from 30 to 180° F.

Abstract: Multifunctional coatings and chemical additives, comprising of lubricant, micro/nano-textured particles, emulsifiers, hydrogel polymers, cross-linking agent to modify the hydrogel polymers, antimicrobial to preserve the bio-based materials, and water solvent, are useful in hydraulic fracturing operation either directly applied on the surface of proppants, or/and mixed with other friction reducer additives to totally or partially substitute the regular friction reducer chemicals, alternatively, as additive components blended or mixed into regular fracturing fluid for easily pumping proppants downhole and stabilizing the pumping pressure; beneficial to the well productivity, effectively suppress and mitigate the risk of respirable microcrystalline dust as the coated materials are transported and handled in the manufacturing plant, terminal, and oil application fields without a need for drying operation on the coating products.

Abstract: Multifunctional coatings and chemical additives, comprising of lubricant, micro/nano-textured particles, emulsifiers, hydrogel polymers, cross-linking agent to modify the hydrogel polymers, antimicrobial to preserve the bio-based materials, and water solvent, are useful in hydraulic fracturing operation either directly applied on the surface of proppants, or/and mixed with other friction reducer additives to totally or partially substitute the regular friction reducer chemicals, alternatively, as additive components blended or mixed into regular fracturing fluid for easily pumping proppants downhole and stabilizing the pumping pressure; beneficial to the well productivity, effectively suppress and mitigate the risk of respirable microcrystalline dust as the coated materials are transported and handled in the manufacturing plant, terminal, and oil application fields without a need for drying operation on the coating products.

Abstract: Chemical additives useful for hydraulic fracturing operation are comprising of lubricant/nonpolar solvents; hydro-dual-phobic domains as core encapsulated by emulsifiers as shell, suspended in water by hydrogel polymers as hydrophilic domains; soy protein isolate (SPI) and sweet rice flour were modified with crosslinking polymers of isocyanate as hydrophobic domains, which is incorporated into the frac fluid as a standard alone friction reducer solution or as an enhancer of frac fluid viscosity of the final frac fluid products in high salinity brines having a concentration as high as 25.0% at an ambient temperature at a downhole well temperature from 30 to 180° F.

Abstract: A composite wood panel having a first and a second longitudinal edge comprising an essentially parallel first surface and second surface, a core, a spacer integrally formed in or attached in the core on at least the longitudinal edges wherein the spacer extends from an edge a pre-determined distance whereby upon placing one panel adjacent to a second panel a spacer of the first panel will abut a spacer of or an edge of a second panel thereby forming at least a first aperture between the adjacent panels wherein an aperture is located between adjacent edges of the panels. A spacer can push into its panel upon linear expansion of a panel. The spacer can be, e.g., a tongue, edge profile, or separate spacing material. Methods for making and using panels are disclosed.

Abstract: A composite wood panel having a first and a second longitudinal edge comprising an essentially parallel first surface and second surface, a core, a spacer integrally formed in or attached in the core on at least the longitudinal edges wherein the spacer extends from an edge a pre-determined distance whereby upon placing one panel adjacent to a second panel a spacer of the first panel will abut a spacer of or an edge of a second panel thereby forming at least a first aperture between the adjacent panels wherein an aperture is located between adjacent edges of the panels. A spacer can push into its panel upon linear expansion of a panel. The spacer can be, e.g., a tongue, edge profile, or separate spacing material. Methods for making and using panels are disclosed.

Abstract: A method for the production of a wood composite board is provided that comprises the steps of: providing a quantity of wood in the form of strands; coating the wood strands with a binder composition to from coated strands; forming a mat from the coated strands; exposing said mat to steam; ventilating steam; and pressing the mat, at a high temperature, to form the wood composite board having a final thickness.

Abstract: An overall method of making engineered strand wood products in relation to a number of different possible criteria is provided. Such a method may involve any combination of different screening procedures to determine the best wood sources from which individual strands may be prepared. Such screening procedures may include initial determinations of certain physical characteristics of individual logs, further or initial determinations of certain physical characteristics of portions of sawn logs, further or initial determinations of certain physical characteristics of individual strands, and any combinations thereof. Additionally, after the initial physical characteristic sorting is completed, optionally the wood may be cut into uniformly sized and shaped strands for incorporation within a target strand product.

Abstract: The present disclosure is directed toward a process for the simultaneous production of two different types of engineered wood products, or oriented strand wood products, each product having different predetermined properties. The present disclosure provides a process which has enhanced utilization of wood resources and can simultaneously produce engineered wood product of various grades and properties from the same log source.

Abstract: The present teachings are directed toward a process for the production of engineered wood products, or oriented strand wood products, having certain desired or predetermined properties by selection of the strands used in the products. The present teachings provide a process which has enhanced utilization of wood resources, reduced product variability, and can produce engineered wood product of various grades and properties on the same production line.

Abstract: Lighweight lignocellulosic board materials, such as oriented strand board and others, having reduced densities while maintaining suitable mechanical properties, and methods for their manufacture.

Abstract: A method for the production of a wood composite board is provided that comprises the steps of: providing a quantity of wood in the form of strands; coating the wood strands with a binder composition to from coated strands; forming a mat from the coated strands; exposing said mat to steam; ventilating steam; and pressing the mat, at a high temperature, to form the wood composite board having a final thickness.

Abstract: Lighweight lignocellulosic board materials, such as oriented strand board and others, having reduced densities while maintaining suitable mechanical properties, and methods for their manufacture.