Patents by Inventor Feng-Huei Lin

Feng-Huei Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220226672
    Abstract: A focused ultrasound device and method for dermatological treatment. The focused ultrasound device includes a focused ultrasound applicator, an automatic motion mechanism, a driver, a computer, a software operation interface. In addition, the focused ultrasound method for dermatological treatment utilizes the same focused ultrasound applicator, to achieve coaxial deep layer and shallow layer ablation treatment of the skin.
    Type: Application
    Filed: June 10, 2019
    Publication date: July 21, 2022
    Applicant: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: GIN-SHIN CHEN, FENG-HUEI LIN, JIUN-JUNG CHEN, CHIA-CHING PAN
  • Publication number: 20220118441
    Abstract: Provided herein is a kit for isolation of platelet-rich plasma, comprising a first isolation tube and a second isolation tube. The first isolation tube comprises a first opening and a second opening, and the second isolation tube comprises a first portion, a second portion, and a filter; wherein the first portion has a third opening, the filter is disposed between the first portion and the second portion, the second opening has a diameter in a range of 1 to 5 mm and the filter has a pore size in a range of 1.5 to 4 ?m.
    Type: Application
    Filed: October 15, 2020
    Publication date: April 21, 2022
    Applicant: KARTIGEN BIOMEDICAL INC.
    Inventors: Hwa-Chang Liu, Feng-Huei Lin, Chun-Che Yen
  • Publication number: 20200330114
    Abstract: The present invention discloses an therapeutic ultrasonic device consisting of at least one arc ultrasonic transducer that can be assembled. The arc ultrasonic transducer comprises a protruding part, a concave part and a plurality of piezoelectric vibrating parts. The protruding part and the concave part are disposed at two ends of the arc ultrasonic transducer respectively, and the piezoelectric vibrating parts are disposed at the inner arc face of the arc ultrasonic transducer. Various numbers of arc ultrasonic transducers can be used in assembled structure or non-assembled structure according to different body size and focal zones of various target tissue. Thus the therapeutic ultrasonic device of the present invention is widely used in treatment of various indications.
    Type: Application
    Filed: January 8, 2018
    Publication date: October 22, 2020
    Inventors: Gin-Shin CHEN, Li-Chen CHIU, Jiun-Jung CHEN, Feng-Huei LIN
  • Publication number: 20200308525
    Abstract: A cell culture device comprises a top layer, a diffusion layer, and a suspension layer. The diffusion layer comprises at least one diffusion channel. The suspension layer comprises multiple suspension units. The multiple suspension units are connected to the diffusion channel. A fluid is conducted through the diffusion channel and flow into the suspension units for drop suspended. Cells are cultivated in the fluid suspended in the suspension unit. The cell culture device can be used in an electromagnetic cell culturing system. The electromagnetic cell culturing system is a combination of hanging drop method, microfluidic technology and electromagnetic stimulation. The electromagnetic cell culturing system can improve the growth of cells and also is capable of continuously providing culture medium into the cell culture device. The cell culture device can be used to cultivate large quantity of cells with high productivity and stable quality.
    Type: Application
    Filed: March 12, 2020
    Publication date: October 1, 2020
    Inventors: FENG-HUEI LIN, SHU-WEI HUANG, SHIAN-CHIUAN TZENG, KUO-HSUN TSENG
  • Publication number: 20200197572
    Abstract: The present invention relates to a three-dimensional (3D) tissue-like implant for transplanting to a subject in need comprising a cell cluster comprising mesenchymal stem cells (MSCs) and specific cells differentiated therefrom. The present invention also relate to a method of preparing a 3D-tissue-like implant from MSCs, particularly by seeding MSCs in alginate scaffolds and culturing the alginate scaffolds with MSCs in a 3-D perfusion condition. Further, the present invention provides a method for treating a defect in a recipient patient in need by administering a 3D tissue-like implant as described herein to the patient at a defective site e.g. a bone defective site.
    Type: Application
    Filed: December 24, 2018
    Publication date: June 25, 2020
    Applicant: National Health Research Institutes
    Inventors: Feng-Huei LIN, Jui-Sheng SUN, Ching-Yun CHEN, Chih-Ying CHI
  • Patent number: 10111814
    Abstract: The present invention discloses a desensitizing toothpaste. Based on the total weight of the desensitizing toothpaste, the desensitizing toothpaste includes: from 5% to 40% by weight of DP-bioglass; from 1% to 5% by weight of thickening agents; from 25% to 35% by weight of humectant; and from 1% to 5% by weight of surfactant, wherein the DP-bioglass includes: 8.4% of Na2O, 40.6% of CaO, 39% of SiO2, and 12% of P2O5 based on the total weight of the DP-bioglass. With the implementation of the present invention, the indication of dentin hypersensitivity can be greatly relieved.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: October 30, 2018
    Assignee: NATIONAL TAIPEI UNIVERSITY OF TECHNOLOGY
    Inventors: Feng-Huei Lin, Chun-Pin Lin, Chia-Ming Chang, Tzu-Piao Tang, Chung-King Hsu, Hsu-Wei Fang, Hsuan-Yu Chen
  • Patent number: 10066208
    Abstract: The present invention is related to a kit comprising: (a) a mesenchymal stem cell; (b) a gelatin-hyaluronan-chondroitin tri-copolymer scaffold; (c) a kartogenin; and (d) a bioreactor. The present invention is also related to a method for promoting differentiation of a mesenchymal stem cell into cartilage tissue, comprising: (a) culturing the mesenchymal stem cell on a gelatin- hyaluronan-chondroitin tri-copolymer scaffold in the presence of a kartogenin; and (b) culturing the mesenchymal stem cell and the gelatin-hyaluronan-chondroitin tri-copolymer scaffold in a bioreactor.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: September 4, 2018
    Assignee: NATIONAL TAIWAN UNIVERSITY
    Inventors: Feng-Huei Lin, Jui-Sheng Sun, Chunching Li, Ching-Yun Chen, Cherng-Jyh Ke
  • Patent number: 9782385
    Abstract: An artificial tears solution combination is composed mainly of an anti-inflammation and anti-oxidation material, a liquid viscosity-enhancing agent, and an artificial tears solution. The artificial tears solution combination is capable keeping moisture, and meanwhile having anti-inflammation and anti-oxidation capabilities. As such, it can prolong the liquid retention on ocular surfaces, to effective reduce the repeated dosing, and shorten the schedule for the dry eye syndrome.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: October 10, 2017
    Assignee: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: Feng-Huei Lin, Hsu-Wei Fang, Ching-Li Tseng, Ya-Jung Hung
  • Patent number: 9662350
    Abstract: A pharmaceutical composition for inhibiting inflammation is provided. The pharmaceutical composition comprises (a) hyaluronic acid, (b) a vitamin and (c) a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: May 30, 2017
    Assignee: CHINA MEDICAL UNIVERSITY
    Inventors: Feng-Huei Lin, Teng-Le Huang, Horng-Chaung Hsu, Chun-Hsu Yao, Yueh-Sheng Chen, Wen-Yu Su
  • Publication number: 20160317491
    Abstract: An artificial tears solution combination is composed mainly of an anti-inflammation and anti-oxidation material, a liquid viscosity-enhancing agent, and an artificial tears solution. The artificial tears solution combination is capable keeping moisture, and meanwhile having anti-inflammation and anti-oxidation capabilities. As such, it can prolong the liquid retention on ocular surfaces, to effective reduce the repeated dosing, and shorten the schedule for the dry eye syndrome.
    Type: Application
    Filed: April 29, 2016
    Publication date: November 3, 2016
    Inventors: Feng-Huei Lin, Hsu-Wei Fang, Ching-Li Tseng, Ya-Jung Hung
  • Patent number: 9457000
    Abstract: Ophthalmic irrigating solutions are disclosed. The ophthalmic irrigating solution comprises: a) ?-polyglutamic acid (?-PGA) and/or salt thereof in an amount effective to increase the viscosity of the irrigating solution, and b) an ophthalmically acceptable aqueous vehicle for the ?-PGA and/or salt thereof. Also disclosed is a method of irrigating ocular tissues of a patient, in which the method comprises introducing to the ocular tissues of the patient an ophthalmic irrigating solution comprising ?-PGA) and/or salt thereof in an amount sufficient to irrigate the ocular tissues of the patient.
    Type: Grant
    Filed: June 16, 2013
    Date of Patent: October 4, 2016
    Assignee: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: Yu-Chun Chen, Wen-Yu Su, Yen-Hsien Lee, Ko-Hua Chen, Feng-Huei Lin
  • Publication number: 20160145574
    Abstract: The present invention is related to a kit comprising: (a) a mesenchymal stem cell; (b) a gelatin-hyaluronan-chondroitin tri-copolymer scaffold; (c) a kartogenin; and (d) a bioreactor. The present invention is also related to a method for promoting differentiation of a mesenchymal stem cell into cartilage tissue, comprising: (a) culturing the mesenchymal stem cell on a gelatin- hyaluronan-chondroitin tri-copolymer scaffold in the presence of a kartogenin; and (b) culturing the mesenchymal stem cell and the gelatin-hyaluronan-chondroitin tri-copolymer scaffold in a bioreactor.
    Type: Application
    Filed: April 30, 2015
    Publication date: May 26, 2016
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Feng-Huei Lin, Jui-Sheng Sun, Chunching Li, Ching-Yun Chen, Cherng-Jyh Ke
  • Publication number: 20150094279
    Abstract: A pharmaceutical composition for inhibiting inflammation is provided. The pharmaceutical composition comprises (a) hyaluronic acid, (b) a vitamin and (c) a pharmaceutically acceptable carrier.
    Type: Application
    Filed: August 6, 2014
    Publication date: April 2, 2015
    Inventors: Feng-Huei LIN, Teng-Le HUANG, Horng-Chaung HSU, Chun-Hsu YAO, Yueh-Sheng CHEN, Wen-Yu SU
  • Patent number: 8916207
    Abstract: A corneal cover or corneal implant to be placed within or onto the surface of the cornea is made of bony fish scales and a contact lens is made of bony fish scales.
    Type: Grant
    Filed: March 3, 2010
    Date of Patent: December 23, 2014
    Assignee: Body Organ Biomedical Corp.
    Inventors: Chien-Cheng Lin, Horng-Ji Lai, Shang-Ming Lin, Feng-Huei Lin
  • Patent number: 8889106
    Abstract: A non-alcohol mouthwash composition without chemical antibacterial medicament is disclosed. The non-alcohol mouthwash composition includes from 0.03% to 1.5% of ?-polyglutamic acid (?-PGA) and from 0.5% to 4% of surfactant, all percentages based on the total weight of the mouthwash composition. The non-alcohol mouthwash composition preferably includes from 0.4% to 1.5% by weight, or more preferably from 0.8% to 1.3% by weight, of ?-PGA. Containing no chemical antibacterial medicament, the non-alcohol mouthwash composition can effectively inhibit bacterial growth in the oral cavity without irritating the oral mucosa.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: November 18, 2014
    Inventors: Feng-Huei Lin, Chun-Pin Lin, Hsuan-Yu Chen, Tzu-Piao Tang, Hsu-Wei Fang, Chung-King Hsu, Chia-Ming Chang
  • Patent number: 8889626
    Abstract: The present invention relates to a method for manufacturing a triple cross-linked collagen, which comprises the following steps: providing a soluble collagen sample; mixing the collagen sample with a first cross-linking agent to form a one cross-linked collagen; mixing the first cross-linked collagen with a second cross-linking agent to form a second cross-linked collagen; and mixing the second cross-linked collagen with a third cross-linking agent to form a triple cross-linked collagen, wherein each of the first cross-linking agent, the second cross-linking agent, and the third cross-linking agent is selected from the group consisting of an aldehyde cross-linking agent, an imine cross-linking agent, and an epoxide cross-linking agent. In addition, the first cross-linking agent is different form the second cross-linking agent, and the third cross-linking agent is different form the first cross-linking agent and the second cross-linking agent.
    Type: Grant
    Filed: April 10, 2012
    Date of Patent: November 18, 2014
    Assignee: Sunmax Biotechnology Co., Ltd.
    Inventors: Yu Te Lin, Chien Hsin Lin, Hsiang Yin Lu, Feng Huei Lin
  • Publication number: 20140314687
    Abstract: A non-alcohol mouthwash composition without chemical antibacterial medicament is disclosed. The non-alcohol mouthwash composition includes from 0.03% to 1.5% of ?-polyglutamic acid (?-PGA) and from 0.5% to 4% of surfactant, all percentages based on the total weight of the mouthwash composition. The non-alcohol mouthwash composition preferably includes from 0.4% to 1.5% by weight, or more preferably from 0.8% to 1.3% by weight, of ?-PGA. Containing no chemical antibacterial medicament, the non-alcohol mouthwash composition can effectively inhibit bacterial growth in the oral cavity without irritating the oral mucosa.
    Type: Application
    Filed: June 28, 2013
    Publication date: October 23, 2014
    Inventors: Feng-Huei Lin, Chun-Pin Lin, Hsuan-Yu Chen, Tzu-Piao Tang, Hsu-Wei Fang, Chung-King Hsu, Chia-Ming Chang
  • Publication number: 20140314694
    Abstract: The present invention discloses a desensitizing toothpaste. Based on the total weight of the desensitizing toothpaste, the desensitizing toothpaste includes: from 5% to 40% by weight of DP-bioglass; from 1% to 5% by weight of thickening agents; from 25% to 35% by weight of humectant; and from 1% to 5% by weight of surfactant, wherein the DP-bioglass includes: 8.4% of Na2O, 40.6% of CaO, 39% of SiO2, and 12% of P2O5 based on the total weight of the DP-bioglass. With the implementation of the present invention, the indication of dentin hypersensitivity can be greatly relieved.
    Type: Application
    Filed: June 20, 2013
    Publication date: October 23, 2014
    Inventors: Feng-Huei LIN, Chun-Pin LIN, Chia-Ming CHANG, Tzu-Piao TANG, Chung-King HSU, Hsu-Wei FANG, Hsuan-Yu CHEN
  • Publication number: 20140295574
    Abstract: A method is provided for modifying a radioactive carbon nanotube (CNT) carrier. Magnetic molecules are used. The modified CNT is highly specified to disease. Surface of the CNT has functional grafts for catching antigen/antibody. Antigen/antibody thus caught on the surface is increased in number. Thus, the present invention improves sensitivity and accuracy of disease detection and greatly saves cost. The present invention can be applied for sample purification or massive disease detection.
    Type: Application
    Filed: August 5, 2013
    Publication date: October 2, 2014
    Applicant: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Kuan-Yin Chen, Chun-Ying Chen, Meng-Jun Fu, Feng-Huei Lin, Chia-Ching Liu
  • Publication number: 20140295433
    Abstract: A detection method for cancer is provided. Magnetic carbon beads are used. The carbon beads are highly specified to a cancer. Surface area of grafted antigen are broadened by grafting functional molecules. Number of antigen is increased on the surface. Thus, the present invention improves sensitivity and accuracy of disease detection and greatly saves cost. The present invention can be applied for sample purification or massive disease detection.
    Type: Application
    Filed: August 5, 2013
    Publication date: October 2, 2014
    Applicant: Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C.
    Inventors: Chun-Ying Chen, Kuan-Yin Chen, Meng-Jun Fu, Chin-Yan Tsai, Feng-Huei Lin, Chia-Ching Liu