Abstract: This disclosure provides myostatin and activin A peptide immunogen constructs, compositions and methods for their use in, for example, maintaining and improving muscle physiology and/or performance (e.g., increasing muscle mass, strength, function, tone or endurance), preventing and/or treating muscular or musculoskeletal injury, preventing and/or treating disorders associated with muscle loss, lack of muscle strength, insufficient muscle growth, muscle wasting, sarcopenia, or cachexia.

Abstract: A method and a device for improving performance of a data processing model, a storage medium and an electronic device are provided. A piece of data in a determined test data read currently is determined as target data. Outlier detection parameters in a detection module are acquired. Detection of concept drift is performed on the data processing model based on the target data and the outlier detection parameters. A detection module is triggered to update each of the outlier detection parameters and the data processing model is retrained when concept drift is successfully detected. After the data processing model is already trained, a piece of data to be read next is determined as the target data, the updated outlier detection parameters in the detection module are acquired, and the detection is resumed until all the pieces of data in the test data stream are read.

Abstract: Provided herein are human Cluster of Differentiation 6 (CD6) binding molecules and nucleic acid sequences encoding such molecules. In particular embodiments, provided herein are human CD6 binding molecules (e.g., nanobodies) having a first, and optionally a second, single monomeric variable antibody domain (SMVAD) that comprises certain CDRs, and methods for using such molecules to treat T-cell related diseases (e.g., cancer, such as T-cell lymphoma). In certain embodiments, the SMVAD comprises camelid, human, or humanized framework regions.

Abstract: A method for performing a transcapacitance absolute sensing (TABS) scheme is provided. The method comprises: obtaining a first absolute capacitance sensing (ABS) profile associated with the first subset of the plurality of electrodes and a second ABS profile associated with the second subset of the plurality of electrodes; obtaining a first TABS profile associated with the first subset of the plurality of electrodes and a second TABS profile associated with the second subset of the plurality of electrodes; determining a first combined sensing profile and a second combined sensing profile based on the first ABS profile, the second ABS profile, the first TABS profile, and the second TABS profile; and performing object detection based on the first combined sensing profile and the second combined sensing profile.

Abstract: A delay-enhanced inverter circuit (DE-inverter) includes: a first non-delay-enhanced inverter circuit (NE-inverter) having an output at a first node and an input at a second node; and a capacitive device feedback-coupled between the first node and the second node, the capacitive device including: a first positive-channel metal-oxide (PMOS) field-effect transistor (FET) (PFET) feedback-coupled between the first node and the second node, the first PFET having a capacitor-configuration; and a first negative-channel metal-oxide (NMOS) FET (NFET) feedback-coupled between the first node and the second node, the first NFET having a capacitor-configuration.

Abstract: Disclosed in the present invention are a drug intermediate and a preparation method therefor, and specifically disclosed are a compound as represented by formula (I) and a preparation method therefor.

Abstract: A website performance optimization method includes creating performance baseline data, performing performance optimization for each website core scenario related to performance data, and outputting a performance test report and runtime information data, determining a performance change condition of the website based on the performance baseline data, the performance test report and the runtime information data, and determining whether to end a performance optimization cycle based on the performance change condition.

Abstract: A bearing (20) is provided for a machine (26), such as a hot leveler, in which at least part of the bearing will be subjected to a temperature of at least 150° C. during use of the machine. The bearing has a sealed space containing rolling elements (13) and a high temperature-resistant lubricating grease (22) that is an admixture of a thickener and a synthetic base oil. The high temperature-resistant lubricating grease has a dropping point of at least 250° C. and an NLGI consistency grade of 1.0 to 1.5. At least one high temperature resistant seal (24) serves to seal the sealed space.

Abstract: A data receiving circuit, data receiving system and storage apparatus are provided. The data receiving circuit includes: a first amplification circuit configured to receive a data signal, first and second reference signals, perform first comparison on the data signal and first reference signal to output a first signal pair and perform second comparison on the data signal and second reference signal to output a second signal pair; a decision equalization enable circuit configured to receive an enable signal and feedback signal and output a control signal where the enable signal has a first level value period, a level value of the control signal varies with that of the feedback signal; and a second amplification circuit configured to receive the first or second signal pair based on the control signal and output first and second output signals.

Abstract: The present invention relates to use of a nitroxoline compound in enhancing the effect of an antibacterial agent. In particular, the present invention relates to use of a compound represented by formula (I) or a pharmaceutically acceptable salt thereof in enhancing the antibacterial effect of the antibacterial agent. When the compound represented by formula (I) of the present invention is used in combination with the antibacterial agent, a synergistic or additive effect can be produced on the antibacterial agent, thereby enhancing the antibacterial effect, particularly for the antibacterial effect of a multi-medicament medicament-resistant strain.

Abstract: A solid-phase method for the manufacture of a cathode active material includes combining a metallic feedstock with an alkali metal source to form a reaction mixture. The metallic feedstock includes elemental transition metals. The method further includes heating the reaction mixture to induce oxidation of the metallic feedstock and provide a calcined mixture, and forming the cathode active material from the calcined mixture. The method simplifies the typical process by which cathode active materials are made, directly using metal or alloy starting materials to provide cathode active material with improved electrochemical properties. Electrochemical cells including the cathode active materials described herein are also described.

Abstract: A method for the manufacture of a cathode active material includes contacting a transition metal oxyhydroxide with an alkali metal source to form an oxyhydroxide intermediate having alkali metal cations inserted therein, and heat treating the oxyhydroxide intermediate to form the cathode active material. Cathode active materials and oxyhydroxide metal precursor compositions are also described herein.

Abstract: A nanoparticle complex comprises a bifunctional binder capable of non-covalently binding to the lipid nanoparticle in the nanoparticle complex.

Abstract: A data processing method includes: displaying a document source control in a target application; displaying a to-be-authorized-document list in response to a trigger operation on the document source control, the to-be-authorized-document list including one or more document titles, the one or more document titles including a title that is in a document application and that corresponds to document data associated with a first object, and the first object being logged in to the document application through the target application; and displaying a first authorized-document list including a first title in response to a trigger operation on the to-be-authorized-document list (S103), the first title being a triggered document title, and the target application having a permission to perform service processing on document data corresponding to the first title.

Abstract: Disclosed herein are molecular ionic composite (MIC) polymer electrolytes. The MIC electrolytes described may be formulated to provide enhanced mechanical properties, improved ionic transport, and stable electrochemical performance across a broad temperature range. The compositions and methods presented are adaptable and may be tailored for various battery applications, including but not limited to solid-state lithium batteries or high-voltage lithium batteries.

Abstract: A delay-enhanced inverter circuit (DE-inverter) includes: a non-delay-enhanced inverter circuit (NE-inverter) having an output at a first node and an input at a second node; and a capacitive device feedback-coupled between the first node and the second node. The capacitive device includes: a first positive-channel metal-oxide (PMOS) field-effect transistor (FET) (PFET) feedback-coupled between the first node and the second node, the first PFET having a capacitor-configuration; and a first negative-channel metal-oxide (NMOS) FET (NFET) feedback-coupled between the first node and the first reference voltage, the first NFET having a capacitor-configuration.

Abstract: The present disclosure relates to a trench-type DMOS device and manufacturing method therefor. The trench-type DMOS device includes an expansion gate layer disposed on an inner surface of a gate insulation layer, and the expansion gate layer includes a first expansion gate region with a second conduction type, a second expansion gate region with a first conduction type, and a third expansion gate region, which improves a contradiction relationship between voltage resistance and specific on-resistance of the trench-type DMOS device. Therefore, the trench-type DMOS device has both high voltage resistance and low specific on-resistance. The trench-type DMOS device has a longitudinal voltage resistance structure, which reduces device area and further decreases device on-resistance. At the same time, a source region and a drain region in the trench-type DMOS device may be led out on its front surface, which is compatible with CMOS.

Abstract: Provided herein are human C6 binding molecules and nucleic acid sequences encoding such molecules. In particular embodiments, provided herein are human C6 binding molecules (e.g., monoclonal antibodies or antigen binding fragments thereof) with particular light and/or heavy chains variable regions, or light chain and/or heavy chain CDRs, and methods for using such molecules to treat a disease, such as a complement-mediated disease.

Abstract: The present disclosure provides a DMOS device with a junction field plate and its manufacturing method. A drain region is located on a surface of a semiconductor substrate. A source region is located in the semiconductor substrate at a bottom of a first trench. A gate electrode is located at the bottom of the first trench. The junction field plate improves an effect on reducing surface resistance. At the same time, a depth of trenches in the DMOS device may be reduced, and thereby a depth-to-width ratio of the device is reduced, improving the feasibility of increasing a voltage resistance level. Both the source region and the drain region in the DMOS device are led out on a same surface. A second doped polycrystalline silicon layer includes a first doped sublayer and a second doped sublayer with different conduction types.

Abstract: A double-row conveyor belt feeding apparatus includes a charging conveyor belt; a box body limiting baffle configured to block box bodies from entering a first conveyor belt and a second conveyor belt; box body limiting push rods configured to limit and fix a third row of box bodies; and a box body moving push rod configured to transfer a first row of box bodies and a second row of box bodies and to be driven to push the first row of box bodies to move by pushing the second row of box bodies, so as to make the first row of box bodies move onto the first conveyor belt. After the first row of box bodies move onto the first conveyor belt, the box body moving push rods are configured to be driven to cause the second row of box bodies to move backwards onto the second conveyor belt.