Abstract: A hardfacing process includes depositing a clad layer having a thickness greater than about 1 mm (0.04 in) on a surface of the component by arc welding, and creating a heat affected zone directly below the clad layer due to the depositing. The heat affected zone may be a region of the component where a lowest hardness is more than 40% lower than a base hardness of the component below the heat affected zone. The method may also include heat treating the component after the deposition such that the lowest hardness in the heat affected zone is restored to within about 15% of the base hardness of the component.

Abstract: A system for automated assembly and welding is disclosed. The system includes a pallet for receiving incoming workpieces; a workpiece holder having a plurality of electromagnets; a handling robot configured to transport incoming workpieces from the pallet to the workpiece holder; and a controller in communication with the workpiece holder and the handling robot. The controller is configured to determine an orientation of a workpiece positioned on the workpiece holder, and to selectively adjust an activation state of one or more electromagnets of the workpiece holder based upon the orientation of the workpiece. A method of assembling and welding workpieces is also disclosed.

Abstract: The invention relates to a system for the automatic manufacture of wind turbine blades using die halves (2,3) wherein by applying dry fiber mats, two complementary shells are molded whereby the attachment thereof will result in the blade to be obtained, head-bearing means (5,6) being arranged with respect to the die halves (2,3), said means being susceptible to selectively having demolding agent, paint, adhesive application accessories or a machining accessory, and head-bearing means (13) having a functional assembly capable of applying the dry fiber mats in the die halves (2,3).

Abstract: An apparatus for the heat-treating of a heat-hardenable steel cruciform article having a weld seam includes a heating element to heat the weld seam to a point that an austenitic transformation occurs, and a quenching chamber to cool the weld seam, causing the formation of Martensite and an associated expansion. The quenching is rapid since slow quenching may allow a crystalline phase other than martensite to form. The apparatus may comprise rollers operable to convey the welded cruciform article through the apparatus at a speed such that the weld seam is subjected to heating for a predetermined heat time sufficient to cause a formation of martensite there within, and such that the heated portion reaches the quenching chamber and is quenched to create a substantial amount of martensite, e.g., an amount sufficient to cause expansion of the part.

Abstract: A system for automated assembly and welding is disclosed. The system includes a pallet for receiving incoming workpieces; a workpiece holder having a plurality of electromagnets; a handling robot configured to transport incoming workpieces from the pallet to the workpiece holder; and a controller in communication with the workpiece holder and the handling robot. The controller is configured to determine an orientation of a workpiece positioned on the workpiece holder, and to selectively adjust an activation state of one or more electromagnets of the workpiece holder based upon the orientation of the workpiece. A method of assembling and welding workpieces is also disclosed.

Abstract: An apparatus for the heat-treating of a heat-hardenable steel cruciform article having a weld seam includes a heating element to heat the weld seam to a point that an austenitic transformation occurs, and a quenching chamber to cool the weld seam, causing the formation of Martensite and an associated expansion. The quenching is rapid since slow quenching may allow a crystalline phase other than martensite to form. The apparatus may comprise rollers operable to convey the welded cruciform article through the apparatus at a speed such that the weld seam is subjected to heating for a predetermined heat time sufficient to cause a formation of martensite there within, and such that the heated portion reaches the quenching chamber and is quenched to create a substantial amount of martensite, e.g., an amount sufficient to cause expansion of the part.

Abstract: The present invention relates to a complex comprising a TGF-?1 inhibitor peptide and a cyclodextrin or a derivative thereof. A TGF-?1 inhibitor peptide emulsion comprising cetyl PEG/PPG-10/1 dimethicone is also provided. Processes for the preparation of said complex and said TGF-?1 inhibitor peptide emulsion are also described, as well as its use for the manufacture of a medicament for the treatment of a disease or condition mediated by a TGF-?1.

Abstract: A system and method for monitoring the operating parameters of an electric arc furnace having a primary electrical circuit comprising a primary current transformer. The method includes monitoring the furnace's primary current transformer; collecting data therefrom; transmitting the collected data to a server having an operatively connected monitor; and displaying the collected data on the monitor in substantially real-time. The server also collects information about the performance of the furnace from a programmable logic computer and information entered manually by an operator at a furnace monitoring viewer system, which may also be displayed in substantially real-time on the monitor.

Abstract: A welding method is disclosed. The welding method includes making a weld via laser-arc hybrid welding. The welding method also includes using a fiber laser source in the laser-arc hybrid welding.

Abstract: A system for automated assembly and welding is disclosed. The system includes a pallet for receiving incoming workpieces; a workpiece holder having a plurality of electromagnets; a handling robot configured to transport incoming workpieces from the pallet to the workpiece holder; and a controller in communication with the workpiece holder and the handling robot. The controller is configured to determine an orientation of a workpiece positioned on the workpiece holder, and to selectively adjust an activation state of one or more electromagnets of the workpiece holder based upon the orientation of the workpiece. A method of assembling and welding workpieces is also disclosed.

Abstract: The present disclosure is directed to a work holding system. The work holding system may include a plurality of electromagnets connected to a support structure and configured to fix a magnetic workpiece to the support structure. Further the work holding system may include a controller configured to selectively adjust an activation state of one or more electromagnets based upon a proximity of work being done on the magnetic workpiece.

Abstract: A Method for the treatment of skin fibrosis with a peptide that inhibits TGF-?, and suitable compositions for its administration. The method includes in particular, the use of peptide P144, a compound that is a known inhibitor of TGF-?, for the treatment of skin fibrosis by topical application. The method is shown effective in an animal model of bleomycin-induced skin sclerosis, to a reduction both of the skin fibrosis and of the content of soluble collagen, without any signs of systemic toxicity being detected. This shows that P144 is effective for topical application in mammals for treating fibrotic skin diseases and pathological scarring of the skin. For the administration of this peptide, stable compositions are also supplied, with pleasant appearance without being greasy, with good spreading characteristics and with a viscosity that permits it to be processed easily in industrial plant, and which are suitable for administering the peptide to humans.

Abstract: An apparatus for the heat-treating of a heat-hardenable steel cruciform article having a weld seam includes a heating element to heat the weld seam to a point that an austenitic transformation occurs, and a quenching chamber to cool the weld seam, causing the formation of Martensite and an associated expansion. The quenching is rapid since slow quenching may allow a crystalline phase other than martensite to form. The apparatus may comprise rollers operable to convey the welded cruciform article through the apparatus at a speed such that the weld seam is subjected to heating for a predetermined heat time sufficient to cause a formation of martensite there within, and such that the heated portion reaches the quenching chamber and is quenched to create a substantial amount of martensite, e.g., an amount sufficient to cause expansion of the part.

Abstract: The present invention is a chemical composition including: Use of the compound with the chemical formula can be applied in pharmaceutical compositions for the treatment of psoriasis.

Abstract: A welding torch includes a nozzle with a first welding wire guide configured to orient a first welding wire in a first welding wire orientation, and a second welding wire guide configured to orient a second welding wire in a second welding wire orientation that is non-coplanar and divergent with respect to the first welding wire orientation. A method of welding includes moving a welding torch with respect to a workpiece joint to be welded. During moving the welding torch, a first welding wire is fed through a first welding wire guide defining a first welding wire orientation and a second welding wire is fed through a second welding wire guide defining a second welding wire orientation that is divergent and non-coplanar with respect to the first welding wire orientation.

Abstract: The present invention relates to large surface distributed pressure sensors comprising at least two flexible substrates, at least of one of these being entirely or partially coated by a layer of polythiophene containing repetitive structural units with formula (I), wherein R1 and R2 are independently a C1-C12 alkyl group or they form a C1-C12 1,n-alkylene group, with n=1-12, optionally substituted by a C1-C12 alkyl group, C2-C12 alkene, vinylene, benzyl, phenyl group, a halogen atom, or by an ester, amine, amide or ether functional group, optionally substituted by a C1-C12 alkyl group; and one or more insulating spacers. Said sensors are flexible and easy to manufacture and they may present different symmetric, simple or multilayer configurations, as desired.

Abstract: A welding torch includes a nozzle with a first welding wire guide configured to orient a first welding wire in a first welding wire orientation, and a second welding wire guide configured to orient a second welding wire in a second welding wire orientation that is non-coplanar and divergent with respect to the first welding wire orientation. A method of welding includes moving a welding torch with respect to a workpiece joint to be welded. During moving the welding torch, a first welding wire is fed through a first welding wire guide defining a first welding wire orientation and a second welding wire is fed through a second welding wire guide defining a second welding wire orientation that is divergent and non-coplanar with respect to the first welding wire orientation.

Abstract: Deionisation and clarification process of the aqueous medium used in an electroerosion machine and product for this process, where the electroerosion machines are comprised of a purification circuit for this aqueous medium, which includes an ion exchange phase between some cationic and anionic resins with the aqueous dielectric medium, which has a conductivity of less than 40 ?S/cm, and to which a solution of oxalic acid and phosphoric acid in distilled/deionised water is added in the approximate proportion of oxalic acid between 0.18 and 0.035 moles and phosphoric acid between 1.28 and 2.5 moles per liter of solution.

Abstract: A Method for the treatment of skin fibrosis with a peptide that inhibits TGF-?, and suitable compositions for its administration. The method includes in particular, the use of peptide P144, a compound that is a known inhibitor of TGF-?, for the treatment of skin fibrosis by topical application. The method is shown effective in an animal model of bleomycin-induced skin sclerosis, to a reduction both of the skin fibrosis and of the content of soluble collagen, without any signs of systemic toxicity being detected. This shows that P144 is effective for topical application in mammals for treating fibrotic skin diseases and pathological scarring of the skin. For the administration of this peptide, stable compositions are also supplied, with pleasant appearance without being greasy, with good spreading characteristics and with a viscosity that permits it to be processed easily in industrial plant, and which are suitable for administering the peptide to humans.

Abstract: The present invention relates to methods for determining and predicting the efficacy of therapeutics for the treatment of an individual with asthma based on that individual's ?2-adrenergic receptor. The invention finds particular applicability to the treatment of an individual with asthma with an inhaled corticosteroid or a leukotriene receptor antagonist who is homozygous for arginine at position 16 of the ?2-adrenergic receptor.