Abstract: A system and method for estimating random noise in an image frame or a sequence of image frames are presented. In some embodiments, the method includes performing Global Noise Estimation by comparing current and past filtered frames; converting global noise estimates into local noise estimates using estimated noise parameters based on current input image's local mean intensity; and providing local noise estimates to an adapted generic spatio-temporal filter. A parameter-based noise model is applied in the noise calculation.

Abstract: This invention is directed to methods for treating and preventing influenza infection by inhibiting influenza virus HA maturation processes employing compounds of formula I. It is also directed to combinations for treating and preventing influenza infection comprising compounds of formula I and other agents.

Abstract: A new class of haloalkyl heteroaryl benzamides is described. These compounds show strong activity against hepatitis viruses.

Abstract: Solid dosage formulations of nitazoxanide or a nitazoxanide analogue are provided that comprise a controlled release portion and an immediate release portion. The pharmaceutical composition is typically in the form of a bilayer solid oral dosage form comprising (a) a first layer comprising a first quantity of nitazoxanide or analogue thereof in a controlled release formulation; and (b) a second layer comprising a second quantity of nitazoxanide or analogue thereof in an immediate release formulation. Method of using the formulations in the treatment of hepatitis C are also provided.

Abstract: The invention relates to an injector for injecting fuel into combustion chambers. According to the invention, a valve piston of a control valve is provided with low pressure on both faces thereof. The valve piston is arranged in a valve chamber hydraulically connected to a control chamber and is guided inside a sleeve received in the valve chamber. The valve chamber contains a spring supported on one end against the sleeve and on the other end on the valve piston such that the spring presses the valve piston onto a valve seat and the sleeve onto an opposing bottom surface. The valve piston diameter inside the sleeve corresponds to the effective valve piston diameter at the valve seat.

Abstract: A new approach to objective quality assessment of DCT-coded video sequences, with or without a reference is proposed. The system is comprised of a proprietary segmentation algorithm, a feature extraction process and a nonlinear feed-forward-type neural network for feature analysis. The methods mimic function of the human visual system (HVS): A neural network training algorithm is used for determining the optimal network weights and biases for both system modes of operation. The proposed method allows for assessment of DCT-coded video sequences without the original source being available (pseudo-reference mode). The pseudo-reference mode is also comprised of a proprietary DCT-coded video (MPEG) noise reducer (MNR), co-pending patent application No. 60/592,143.

Abstract: A method of treating viral infections by the administration of a halogenated benzamide derivative according to formula (III): in which R1 is a halogen atom, and R2-R6 are independently hydrogen, hydroxyl, C1-C4 alkyl, —C1-C4 alkoxy, acyloxy, nitro, halogen, —C(O)R7 where R7 is —C1-C4 alkyl, or, aromatic including salts and hydrates of these compounds.

Abstract: The fuel injection system has at least two electrically actuated control valves for controlling the fuel injection; the control valves are each connected via electric lines to an electric control unit. In the fuel injection system, terminal elements for connection of the electric lines are provided. For a first of the control valves, a structural element is provided, on which the terminal elements for all the control valves are disposed, and which can be secured to a housing part of the fuel injection system. At least one electric connecting line from the terminal elements to the second control valve disposed inside a housing part of the fuel injection system is integrated with the structural element.

Abstract: The fuel injection system has at least two electrically actuated control valves for controlling the fuel injection; the control valves are each connected via electric lines to an electric control unit. In the fuel injection system, terminal elements for connection of the electric lines are provided. For a first of the control valves, a structural element is provided, on which the terminal elements for all the control valves are disposed, and which can be secured to a housing part of the fuel injection system. At least one electric connecting line from the terminal elements to the second control valve disposed inside a housing part of the fuel injection system is integrated with the structural element.

Abstract: A method and apparatus for estimating motion of a pixel block in a first frame, the method including searching a first area in a second frame to identify a first matching block that corresponds to the pixel block, the first matching block including a first error value that is a minimum of at least one error criteria between the pixel block and the first matching block, calculating a first motion vector associated with the first matching block. The method further including searching a second area in the second frame to identify a second matching block that corresponds to the pixel block, the second matching block including a second error value that is a minimum of the at least one error criteria between the pixel block and the second matching block, calculating a second motion vector associated with the second matching block and selecting a final motion vector between the first and second motion vectors based on the first and second error value.

Abstract: A halogenated benzamide derivative characterized by greater specificity for viral pathogens and less disruptive to beneficial gut microflora, according to formula (III): in which R1 is a halogen atom, and R2-R6 are independently hydrogen, hydroxyl, C1-C4 alkyl, —C1-C4 alkoxy, acyloxy, nitro, halogen, —C(O)R7 where R7 is —C1-C4 alkyl, or, aromatic including salts and hydrates of these compounds and where at least two of R2-R6 are not hydrogen and where at least one of R2-R6 are hydroxy or acyloxy.

Abstract: A new class of alkylsulfonyl-substituted thiazolide compounds is described. These compounds show strong activity against hepatitis virus.

Abstract: A halogenated benzamide derivative characterized by greater specificity for viral pathogens and less disruptive to beneficial gut microflora, according to formula (III): in which R1 is a halogen atom, and R2-R6 are independently hydrogen, hydroxyl, C1-C4 alkyl, —C1-C4 alkoxy, acyloxy, nitro, halogen, —C(O)R7 where R7 is —C1-C4 alkyl, or, aromatic including salts and hydrates of these compounds.

Abstract: The present disclosure relates to methods for treating viral hepatitis, compounds useful in the treatment of viral hepatitis, and pharmaceutical compositions comprising such compounds. In one embodiment, pharmaceutical compositions comprising nitazoxanide, tizoxanide, or derivatives and/or mixtures thereof are provided, as well as methods of treating hepatitis C using such compositions.

Abstract: A method of treating an infectious disease caused by a pathogen comprising administering to a subject in need thereof an effective amount of one or more compounds that inhibit the function of a molecular chaperone, wherein said compound is other than tizoxanide or nitazoxanide.

Abstract: A new approach to objective quality assessment of DCT-coded video sequences, with or without a reference is proposed. The system is comprised of a proprietary segmentation algorithm, a feature extraction process and a nonlinear feed-forward-type neural network for feature analysis. The methods mimic function of the human visual system (HVS): A neural network training algorithm is used for determining the optimal network weights and biases for both system modes of operation. The proposed method allows for assessment of DCT-coded video sequences without the original source being available (pseudo-reference mode). The pseudo-reference mode is also comprised of a proprietary DCT-coded video (MPEG) noise reducer (MNR), co-pending patent application no. 60/592,143.

Abstract: The invention relates to a quantity control valve for a fuel injection system, used in internal combustion engines, which includes a longitudinal slide that is movable in a valve housing between a first and a second control chamber and that allocates the fuel, flowing in from at least one low-pressure pump, to at least one high-pressure pump. For driving the longitudinal slide, the inflowing fuel is delivered into the first control chamber via a throttle or baffle valve, past the longitudinal slide. In the second control chamber, there is either a restoring spring that urges the longitudinal slide in the direction of its closing position, or the longitudinal slide there has an effective face-end surface area upstream of which a control line containing a throttle valve ends; this end face is smaller in surface area than the effective surface area of the face end in the first control chamber.

Abstract: The present invention relates to a pharmaceutical composition containing a compound of formula I ##STR1## with one of the symbols R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 representing OH, whereas the remaining symbols represent H as antiviral agent.

Abstract: The present invention relates to a pharmaceutical composition containing a compound of formula I ##STR1## with one of the symbols R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 representing OH, whereas the remaining symbols represent H as antiviral agent.

Abstract: Methods for treatment of a parasitic infection of a trematode selected from the group consisting of Schistosoma such as Schistosoma mansoni, Schistosoma haematobium, Schistosoma mekongi, Schistosoma japonicum, and Schistosoma intercalatum, Fasciola such as Fasciola hepatica and Fasciola gigantica, Fasciolopsis buski, Dicrocoelium dendriticun, Heterophyes heterophyes, and Metagonimus yokogawa, the methods comprising administration of a pharmaceutical composition containing as active agent at least one compound selected the group consisting of a compound of formula I: ##STR1## and a compound of formula II: ##STR2##