Abstract: The present invention relates to a non-viral method for the production of modified mesenchymal stem/stromal cells comprising the use of an additive rich in human-derived platelet growth factors, derived from platelet concentrates, aimed to promote the expansion of said cells. The method further comprises the phase of submitting the cells to electroporation and suspending said mixture in the growth-medium enriched in human-derived platelet growth factors and keeping in incubation. In this way, it is possible to achieve a chemical-physical, non-viral method in compliance with the Good Manufacturing Practice Guidelines (GMP) for advanced cell therapy products, allowing transiently or stably transfect/deliver gene constructs based on electric pulses administration to cells. Said production method is particularly simple and advantageous in terms of productivity and cost-effectiveness, when compared to methods involving viral vectors.

Abstract: An arc chamber for a low voltage switching device including an insulating casing, having a first and a second lateral walls, a rear and a front wall, that defines an internal space housing a number or arc-breaking plates, a top wall of the casing having a discharge opening for venting off the gases from the internal space, the discharge opening being covered by a top cover. The arc chamber for a low voltage switching device includes a filter made of an open cell metal foam that is positioned at the discharge opening.

Abstract: A condenser includes a fluid inlet in an upper manifold and a fluid outlet in a lower manifold. The condenser includes multiport tubes provided with a plurality of separate flow channels which are delimited by outer opposite side walls and internal intermediate walls extending between the outer opposite side walls of the tubes. The multiport tubes define a channel space between them. A plurality of cooling plates extend between the upper manifold and the lower manifold. The cooling plates are in thermal contact with the multiport tubes to receive a heat load from fluid in the flow channels. The cooling plates have outer edges which protrude out from the channel space and are directed away from the channel space.

Abstract: Provided is a spring drive cam for a spring drive of a circuit breaker including a disc-like shape configured for rotating around a rotation axis in the spring drive, whereby the disc-like shape comprises a radius (R) that changes depending on an angle (?) of the radius (R) relative to a base angle (?0), and whereby a rate (dR/d?) defined by a change of the radius (R) per change of the angle (?) is ?0.3 mm/°.

Abstract: An air treatment system is described, for a closable room of a vehicle, comprising: an air conditioning device provided with a fan and connectable to the room; an inlet opening for outside air, connected to the air conditioning device; a filtration device for filtering the outside air entering from the inlet opening; a recirculation port; a valve assembly provided with a shutter member, interposed between the inlet opening, the recirculation port and the air conditioning device and movable between a plurality of operating positions, in which it varies the shares of air coming from the inlet opening and the recirculation port; and a control unit to adjust the operating position of the shutter member so as to control the shares of air being drawn from the inlet opening and from the recirculation port and to maintain a predetermined value of overpressure in the room with respect to the outside.

Abstract: An evaporator includes an inlet in a lower manifold, an outlet in an upper manifold, and a multiport tube extending between the lower manifold and the upper manifold. The multiport tube provides a flow path between the lower manifold and the upper manifold. One of the outer side walls of the multiport tube is provided with a first evaporator section with a first heat receiving surface and a second evaporator section with a second heat receiving surface, the first and second evaporator sections passing a heat load received via the respective first and second heat receiving surfaces to a fluid in said multiport tube. The first and second heat receiving surfaces form an angle with each other to align with and contact different surfaces of an object to be cooled.

Abstract: Provided is a spring drive cam for a spring drive of a circuit breaker including a disc-like shape configured for rotating around a rotation axis in the spring drive, whereby the disc-like shape comprises a radius (R) that changes depending on an angle (?) of the radius (R) relative to a base angle (?0), and whereby a rate (dR/d?) defined by a change of the radius (R) per change of the angle (?) is ?0.3 mm/°.

Abstract: An arc chamber 10, 20, 30, 40, 50 for a low voltage switching device comprising an insulating casing 1, having a first and a second lateral walls 2,3, a rear and a front wall 4,5, that defines an internal space housing a number of arc-breaking plates, a top wall 6 of said casing having a discharge opening 101 for venting off the gases from said internal space, said discharge opening 101 being covered by a top cover 7, 37, 47, 57. The arc chamber for a low voltage switching device comprises a filter 11, 21, 31, 41, 51 made of an open cell metal foam is positioned at said discharge opening 101.

Abstract: A method for producing an electrical power device from subsequently manufactured parts by an additive manufacturing technique includes determining a target spatial distribution of a physical property of the electrical power device, the physical property being an electrical property and/or a mechanical property; forming a part of the electrical power device; selecting a physical property of a subsequent part of the electrical power device corresponding to the determined spatial distribution of the physical property such as to be different from a corresponding physical property of the part; and by means of the additive manufacturing technique, forming the subsequent part such that it is at least partially in contact with the part. An electrical power device is obtainable by the method, and the electrical power device may be used as an AC or DC insulator in an HVAC or HVDC apparatus.

Abstract: A surge arrester system includes a surge arrester, and an active cooling system having a cooling interface in contact with the surge arrester and operative to transfer heat from the surge arrester. The active cooling system includes a forced convection apparatus operative to provide forced convection cooling. A circuit breaker system includes a power semiconductor switch and an active cooling system constructed to cool the power semiconductor switch. The active cooling system includes a forced convection apparatus configured to provide forced convection cooling. The power semiconductor switch is in contact with the active cooling system. A surge arrester is disposed adjacent to and in contact with the active cooling system. The active cooling system includes a cooling interface constructed for contact with the surge arrester and operative to provide cooling to the surge arrester. The power semiconductor switch and the surge arrester dissipate power alternatively.

Abstract: An evaporator includes an inlet in a lower manifold, an outlet in an upper manifold, and a multiport tube extending between the lower manifold and the upper manifold. The multiport tube provides a flow path between the lower manifold and the upper manifold. One of the outer side walls of the multiport tube is provided with a first evaporator section with a first heat receiving surface and a second evaporator section with a second heat receiving surface, the first and second evaporator sections passing a heat load received via the respective first and second heat receiving surfaces to a fluid in said multiport tube. The first and second heat receiving surfaces form an angle with each other to align with and contact different surfaces of an object to be cooled.

Abstract: A condenser includes a fluid inlet in an upper manifold and a fluid outlet in a lower manifold. The condenser includes multiport tubes provided with a plurality of separate flow channels which are delimited by outer opposite side walls and internal intermediate walls extending between the outer opposite side walls of the tubes. The multiport tubes define a channel space between them. A plurality of cooling plates extend between the upper manifold and the lower manifold. The cooling plates are in thermal contact with the multiport tubes to receive a heat load from fluid in the flow channels. The cooling plates have outer edges which protrude out from the channel space and are directed away from the channel space.

Abstract: Cooling arrangements are disclosed for solid state circuit breakers. In one arrangement, a MOV is disposed between two pulsating heat pipes. An IGCT is disposed on the other side of each pulsating heat pipe away from the MOV. In another arrangement, a bus bar is integral with a heat spreader disposed between a pulsating heat pipe and an IGCT.

Abstract: A heat exchange device may be based on a pulsating heat pipe and a cooling arrangement. The heat exchange device may include a plurality of pipes to provide fluid paths between a first fluid distribution element and a second fluid distribution element. Each pipe of the plurality of pipes may include a group of channels. Each of the first and second fluid distribution elements may include a plate of a first type. Each plate of the first type may include openings for providing alignment functionality for the plurality of pipes. The first fluid distribution element may include a plate of a second type that may include openings for providing fluid paths between the pipes. The plate of the second type may be positioned on a side of the plate of the first type of plates of the first fluid distribution element that is opposite to the second fluid distribution element.

Abstract: A heat exchanger assembly is disclosed.

Abstract: This invention relates to a cooling apparatus comprising a base plate, an evaporator and a condenser. In order to obtain a simple and efficient cooling apparatus the evaporator is a porous aluminum evaporator having a capillary structure with pores and a plurality of larger sized evaporator channels extending through the evaporator between a second end and the first end of the evaporator. A compensation chamber extending along a second surface of the evaporator receives first fluid from the condenser such that pores opening up into the second surface of the evaporator are provided with first fluid.

Abstract: A surge arrester system includes a surge arrester, and an active cooling system having a cooling interface in contact with the surge arrester and operative to transfer heat from the surge arrester. The active cooling system includes a forced convection apparatus operative to provide forced convection cooling. A circuit breaker system includes a power semiconductor switch and an active cooling system constructed to cool the power semiconductor switch. The active cooling system includes a forced convection apparatus configured to provide forced convection cooling. The power semiconductor switch is in contact with the active cooling system. A surge arrester is disposed adjacent to and in contact with the active cooling system. The active cooling system includes a cooling interface constructed for contact with the surge arrester and operative to provide cooling to the surge arrester. The power semiconductor switch and the surge arrester dissipate power alternatively.

Abstract: A heat exchanger assembly (1) is disclosed.

Abstract: A power device comprises at least one power semiconductor module comprising a wide bandgap semiconductor element; and a cooling system for actively cooling the wide bandgap semiconductor element with a cooling medium, wherein the cooling system comprises a refrigeration device for lowering a temperature of the cooling medium below an ambient temperature of the power device; wherein the cooling system is adapted for lowering the temperature of the cooling medium in such a way that a temperature of the wide bandgap semiconductor element is below 100° C.

Abstract: A cooling device for cooling at least two power electronic devices by a working fluid. The cooling device has a heat receiver portion of the Pulsating Heat Pipe circuit system and a pair of thermo-conducting walls provided on mutually opposite sides of the heat receiver arrangement and sandwiching the heat receiver portion between them. These walls are adapted for being thermally connected to a respective one of the power electronic devices. The cooling device further has a heat dissipator arrangement with a heat dissipator portion of the Pulsating Heat Pipe circuit system and a plurality of fins thermally coupled to the heat dissipator portion for transferring heat from the heat dissipator portion to an external cooling fluid for cooling the working fluid in the heat dissipator portion.