Patents by Inventor Francis Nguyen

Francis Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Variants of vascular endothelial cell growth factor, their uses, and processes for their production
    Publication number: 20060024785
    Abstract: The present invention involves the preparation of vascular endothelial growth factor (VEGF) variants which provide materials that are selective in respect of binding characteristics to the kinase domain region and the FMS-like tyrosine-kinase region, respectively KDR and FLT-1. The respective KDR and FLT-1 receptors are bound by corresponding domains within the VEGF compound domains. The variants hereof define those two binding regions and modify them so as to introduce changes that interrupt the binding to the respective domain. In this fashion the final biological characteristics of the VEGF molecule are selectively modified.
    Type: Application
    Filed: June 3, 2005
    Publication date: February 2, 2006
    Applicant: GENENTECH, INC.
    Inventors: Bruce Keyt, Francis Nguyen, Napoleone Ferrara