Patents by Inventor Francis P. Miller

Francis P. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants
    Patent number: 4870083
    Abstract: The present invention relates to 1,4-disubstituted-piperidinyl compounds and their use as analgesic agents and as muscle relaxants.
    Type: Grant
    Filed: October 11, 1988
    Date of Patent: September 26, 1989
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Albert A. Carr, Thaddeus R. Nieduzak, Francis P. Miller, Stephen M. Sorensen
  • 5-(naphthyl)-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants
    Patent number: 4775689
    Abstract: This invention relates to novel 5-(naphthyl)-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and to their use as antidepressants.
    Type: Grant
    Filed: July 28, 1987
    Date of Patent: October 4, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: John M. Kane, Francis P. Miller
  • 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones and their use as antidepressants
    Patent number: 4775688
    Abstract: This invention relates to novel 5-aryl-2,4-dialkyl-3H-1,2,4-triazole-3-thiones, to the intermediates and processes for their preparation, and to their use as antidepressants.
    Type: Grant
    Filed: May 15, 1987
    Date of Patent: October 4, 1988
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: John M. Kane, Francis P. Miller
  • Tetrahydro-7a-(optionally substituted phenyl)-1H-pyrrolo[1,2-b][1,2,4]-triazole-2(3H)-thiones
    Patent number: 4358457
    Abstract: Compounds of the formula ##STR1## wherein R is H or C.sub.1-5 straight or branched chain alkyl; R.sub.1 is H, C.sub.1-10 straight or branched chain alkyl, allyl or phenyl; and R.sub.2 is phenyl or phenyl substituted with F, Cl, C.sub.1-5 straight or branched chain alkyl, di-F, di-Cl or di-Br; and the pharmaceutically acceptable acid addition salts thereof; are useful as muscle relaxants, anticonvulsants and analgesics.
    Type: Grant
    Filed: July 27, 1981
    Date of Patent: November 9, 1982
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Winton D. Jones, John M. Kane, Francis P. Miller
  • Muscle-relaxant 1,3,4-thiadiazin-2-amines
    Patent number: 4309426
    Abstract: A method of achieving a muscle-relaxing effect in a patient comprises administering to a patient in which a muscle relaxing effect is desired an amount effective to achieve a muscle-relaxing effect of a compound of the formula ##STR1## wherein R is H, or C.sub.1-7 straight or branched chain alkyl;R.sub.1 is H, C.sub.1-7 straight or branched chain alkyl, allyl or phenyl;R.sub.2 is phenyl, phenyl monosubstituted with F, Cl, C.sub.1-4 straight or branched chain alkyl or phenyl disubstituted in the 2- and 4-positions with Cl or C.sub.1-4 straight or branched chain alkyl; andR.sub.3 is H or C.sub.1-4 straight or branched chain alkyl, with the proviso that when R.sub.3 is straight or branched chain alkyl, R.sub.2 is unsubstituted phenyl;or a pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: November 20, 1980
    Date of Patent: January 5, 1982
    Assignee: Richardson-Merrell Inc.
    Inventors: Winton D. Jones, Jr., Francis P. Miller
  • 5-(Chlorophenyl)-6H-1,3,4-thiadiazine-2-amines
    Patent number: 4289767
    Abstract: Compounds of the formula ##STR1## wherein R is H, C.sub.1-5 or 7 -straight or branched chain alkyl or allyl and R.sub.1 is H or Cl andthe pharmacologically acceptable acid addition salts thereof are pharmacologically active as anticonvulsant and anxiolytic agents.
    Type: Grant
    Filed: September 4, 1979
    Date of Patent: September 15, 1981
    Assignee: Richardson-Merrell Inc.
    Inventors: Winton D. Jones, Francis P. Miller
  • 5-(Optionally substituted phenyl)-6H-1,3,4-thiadiazine-2-amines
    Patent number: 4272532
    Abstract: A method of inducing sedation in a patient comprises administering to a patient in which sedation is desired an amount effective for inducing sedation of a compound of the formula ##STR1## wherein R is H, or C.sub.1-5 or 7 -straight or branched chain alkyl:R.sub.1 is H, C.sub.1-5 or 7 -straight or branched chain alkyl or allyl;R.sub.2 is phenyl or phenyl substituted with F, Cl, Br, NO.sub.2, C.sub.1-5 straight or branched chain alkyl, C.sub.1-5 straight or branched chain alkoxy, 2,4-di-Cl, 2,4-di-F or 2,4-di-Br, with the proviso that when the phenyl group is monosubstituted with F, the F atom is not in the o-position; andR.sub.3 is H or C-1-5 straight or branched chain alkyl, with the proviso that when R.sub.3 is straight or branched chain alkyl, R.sub.2 is unsubstituted phenyl; ora pharmaceutically acceptable acid addition salt thereof.
    Type: Grant
    Filed: September 4, 1979
    Date of Patent: June 9, 1981
    Assignee: Richardson-Merrell Inc.
    Inventors: Winton D. Jones, Francis P. Miller