Abstract: A method of increasing production of one or more lipoxins in a subject in need thereof comprising administering to the subject an amount of a compound having the structure: or a pharmaceutically acceptable salt or ester thereof, so as to thereby increase production of the one or more lipoxins in the subject.

Abstract: Apparatus can include an input aperture configured to provide an input beam, primary optics configured to collimate the input beam, a grism situated to receive the collimated input beam and to produce a wavelength dispersed beam, and secondary optics configured to receive and direct the wavelength dispersed beam to a detector. Primary optics can include a primary reflector including an off-axis parabolic mirror, wherein the off-axis parabolic mirror is configured to produce the collimated input beam. Secondary optics can include a first secondary reflector and a second secondary reflector, wherein the first secondary reflector is situated to receive and reflect the wavelength dispersed beam to the second secondary reflector and the second secondary reflector is situated to receive and direct the wavelength dispersed beam to the detector.

Abstract: The present disclosure provides methods for treating hematological malignancies and Ewing's sarcoma using menin inhibitors. Compositions for use in these methods are also provided.

Abstract: A method for forming a surface-relief grating with a desired spatial variation of duty cycle in a layer of photoresist includes: providing a first mask bearing a high-resolution grating of linear features, arranging the first mask at a first distance from a substrate, providing a second mask bearing a variable-transmission grating of opaque and transparent linear features that has a designed spatial variation of duty cycle, arranging the second mask at a distance before the first mask such that the linear features of the variable-transmission grating are orthogonal to the linear features of the high-resolution grating, illuminating the second mask while varying the first distance according to displacement Talbot lithography and also displacing the second mask at an angle to its linear features such that there is substantially no component of modulation with the period of the variable-transmission grating in the energy density distribution that exposes the photoresist.

Abstract: A fit detection system for a respiratory protection device is presented that includes an infrared camera that captures an image sequence of a user wearing the respiratory protection device. The system also includes a temperature change detector that analyzes images in the image sequence and detects a temperature change profile of the respiratory protection device. The system also includes a communication component that communicates a fit indication based on the detected temperature change profile.

Abstract: Composite anode materials and methods of making same, the anode materials including capsules including graphene, reduced graphene oxide, graphene oxide, or a combination thereof, and particles of an active material disposed inside of the capsules. The particles may each include a core and a buffer layer surrounding the core. The core may include crystalline silicon, and the buffer layer may include a silicon oxide, a lithium silicate, carbon, or a combination thereof.

Abstract: Composite anode materials and methods of making same, the anode materials including capsules including graphene, reduced graphene oxide, graphene oxide, or a combination thereof, and particles of an active material disposed inside of the capsules. The particles may each include a core and a buffer layer surrounding the core. The core may include crystalline silicon, and the buffer layer may include a silicon oxide, a lithium silicate, carbon, or a combination thereof.

Abstract: A system for updating a hypercube includes an interface and a processor. The interface is configured to receive an indication to update a cell of the hypercube. The processor is configured to determine a primary dimension value associated with the cell; determine a group of dependencies based at least in part on the primary dimension value, wherein a dependency of the group of dependencies comprises one or more primary dimension values and a pattern; for the dependency of the group of dependencies, determine a set of source locations based at least in part on the one or more primary dimension values and the pattern; and mark the set of source locations as invalid.

Abstract: A system for updating a hypercube includes an interface and a processor. The interface is configured to receive an indication to update a cell of the hypercube. The processor is configured to determine a primary dimension value associated with the cell; determine a group of dependencies based at least in part on the primary dimension value, wherein a dependency of the group of dependencies comprises one or more primary dimension values and a pattern; for the dependency of the group of dependencies, determine a set of source locations based at least in part on the one or more primary dimension values and the pattern; and mark the set of source locations as invalid.

Abstract: A system for determining access for a hypercube includes an interface configured to receive a request for access from a user to data in a location in a hypercube; receive a tree structure with subcubes of the hypercube arranged in a hierarchical structure; and receive a user permission list, wherein an element of the user permission list comprises a permission, a root node, and a set of pruned nodes. The system also includes a processor configured to determine a user permission associated with the data in the location of the hypercube using the user permission list; and provide an indication of the user permission.

Abstract: A system for updating a hypercube includes an interface and a processor. The interface is configured to receive an indication to update a cell of the hypercube. The processor is configured to determine a primary dimension value associated with the cell; determine a group of dependencies based at least in part on the primary dimension value, wherein a dependency of the group of dependencies comprises one or more primary dimension values and a pattern; for the dependency of the group of dependencies, determine a set of source locations based at least in part on the one or more primary dimension values and the pattern; and mark the set of source locations as invalid.

Abstract: A system for updating a hypercube includes an interface and a processor. The interface is configured to receive an indication to update a cell of the hypercube. The processor is configured to determine a primary dimension value associated with the cell; determine a group of dependencies based at least in part on the primary dimension value, wherein a dependency of the group of dependencies comprises one or more primary dimension values and a pattern; for the dependency of the group of dependencies, determine a set of source locations based at least in part on the one or more primary dimension values and the pattern; and mark the set of source locations as invalid.

Abstract: An electrochemically active material including composite particles that each include a graphene-based material shell surrounding nanoparticles of a core material. The composite particles may include a BET surface area of less than about 75 m2/g. The electrochemically active material may be formed into an electrode incorporated within a lithium ion electrochemical cell.

Abstract: A negative electrode of a lithium ion electrochemical cell, the negative electrode including an active electrode material that includes a first component and a second component. The first component may include graphene, silicon, or a combination thereof. The second component may include silicon. The active electrode material may include particles in which the second component is encapsulated by the first component. The negative electrode may have an internal porosity of between 40 to 60 percent.

Abstract: A system for caching includes an interface to receive a portion of a hypercube to evaluate. The hypercube includes cells with a set of the cells having a formula. The system includes a processor to determine term(s) in the formula for each cell of the set of cells; remove from consideration a time dimension and/or a primary dimension for the term(s) in the formula for each cell of the set of cells; determine a set of distinct terms using the term(s); determine whether a total number of terms in the set of cells is larger than a number of distinct terms in the set of distinct terms; and in response to determining that the total number of terms in the set of cells is larger than the number of distinct terms in the set of distinct terms, indicate to cache the set of distinct terms during evaluation.

Abstract: Composite anode materials and methods of making same, the anode materials including capsules including graphene, reduced graphene oxide, graphene oxide, or a combination thereof, and particles of an active material disposed inside of the capsules. The particles may each include a core and a buffer layer surrounding the core. The core may include crystalline silicon, and the buffer layer may include a silicon oxide, a lithium silicate, carbon, or a combination thereof.

Abstract: A composite anode material including an active material including a core of silicon, silicon oxide, or combination thereof encased within a buffer layer including a polymeric material, and a shell encapsulating the active material. The shell may include graphene, graphene oxide, partially reduced graphene oxide, or combinations thereof.

Abstract: Composite anode materials and methods of making same, the anode materials including capsules including graphene, reduced graphene oxide, graphene oxide, or a combination thereof, and particles of an active material disposed inside of the capsules. The particles may each include a core and a buffer layer surrounding the core. The core may include crystalline silicon, and the buffer layer may include a silicon oxide, a lithium silicate, carbon, or a combination thereof.

Abstract: The present application relates to composite particles for a negative electrode of an electrochemical cell, an anode including the composite particles, methods of forming the same. The composite particles each include: a capsule including crumpled sheets of a graphene material; a core encapsulated in the capsule, the core including an electrochemically active material; and carbon nanotubes (CNTs) disposed in capsule, the core, or both the capsule and the core.

Abstract: A composite anode material including an active material including a core of silicon, silicon oxide, or combination thereof encased within a buffer layer including a polymeric material, and a shell encapsulating the active material. The shell may include graphene, graphene oxide, partially reduced graphene oxide, or combinations thereof.