Patents by Inventor Francois Rousseau

Francois Rousseau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240141050
    Abstract: Described herein are treatments and preventions for prurigo nodularis (PN), antibodies and pharmaceutical compositions for use in the treatment or prevention of PN, and uses of an anti-IL-31RA antibody (e.g., nemolizumab) in the manufacture of a medicament for the treatment or prevention of PN. Also described herein are biomarkers of PN and methods of altering or improving these biomarkers via treatments with an antibody that binds to IL-31RA (e.g., nemolizumab).
    Type: Application
    Filed: August 25, 2023
    Publication date: May 2, 2024
    Inventors: Valerie JULIA, Jayendra Kumar KRISHNASWAMY, Christophe PIKETTY, Francois ROUSSEAU
  • Publication number: 20240140367
    Abstract: The invention relates to a liquid recovery system for a motor vehicle where such a recovery system includes at least one liquid intake that communicates with a tank, which is designed to store liquid from the liquid intake, and is designed with an arrangement below the motor vehicle's beltline.
    Type: Application
    Filed: January 9, 2024
    Publication date: May 2, 2024
    Applicant: Valeo Systemes d'Essuyage
    Inventors: Laurent ANDRE-MASSE, Philippe CARRARO, Julien CARRION, Pierre-Francois DUPRAT, Jean-Francois ROUSSEAU, Grégory VILLEMIN
  • Patent number: 11904816
    Abstract: The invention relates to a liquid recovery system for a motor vehicle and to a vehicle including such a recovery system that that includes at least one liquid intake that communicates with a tank and is referred to as the first tank, which is designed to store liquid from the liquid intake and where the liquid intake is arrangeably designed below the vehicle's beltline.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: February 20, 2024
    Assignee: VALEO SYSTEMES D'ESSUYAGE
    Inventors: Laurent Andre-Masse, Philippe Carraro, Julien Carrion, Pierre-Francois Duprat, Jean-Francois Rousseau, Grégory Villemin
  • Patent number: 11840553
    Abstract: The invention relates to monoclonal and/or monovalent antibodies that bind CD47. The invention relates to monoclonal and/or monovalent antibodies that bind CD19. The invention also relates to novel bispecific monoclonal antibodies carrying a different specificity for each binding site of the immunoglobulin molecule, where one of the binding sites is specific for CD47. The invention also relates to novel bispecific monoclonal antibodies carrying a different specificity for each binding site of the immunoglobulin molecule, where one of the binding sites is specific for CD19.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: December 12, 2023
    Assignee: Novimmune SA
    Inventors: Krzysztof Masternak, Nicolas Fischer, Francois Rousseau, Elie Dheilly, Marie Kosco-Vilbois
  • Publication number: 20220411518
    Abstract: Described herein are treatments and preventions for prurigo nodularis (PN), antibodies and pharmaceutical compositions for use in the treatment or prevention of PN, and uses of an anti-IL-31RA antibody (e.g., nemolizumab) in the manufacture of a medicament for the treatment or prevention of PN. Also described herein are biomarkers of PN and methods of altering or improving these biomarkers via treatments with an antibody that binds to IL-31RA (e.g., nemolizumab).
    Type: Application
    Filed: April 6, 2022
    Publication date: December 29, 2022
    Inventors: Valerie JULIA, Jayendra Kumar KRISHNASWAMY, Christophe PIKETTY, Francois ROUSSEAU
  • Publication number: 20220324994
    Abstract: Disclosed are antibodies that specifically bind Toll-like Receptor 4 (TLR-4), and to methods of using the anti-TLR4 antibodies as therapeutics and diagnostic agents.
    Type: Application
    Filed: November 15, 2021
    Publication date: October 13, 2022
    Inventors: Francois ROUSSEAU, Jeremy LOYAU, Nicolas FISCHER, Greg ELSON, Marie KOSCO-VILBOIS
  • Patent number: 11261262
    Abstract: The invention provides heterodimer bispecific antigen-binding molecules that include a first polypeptide that does not include an IgG CH1 domain and a second polypeptide where there is at least one mutation in the IgG CH3 domain that abolishes the ability of the second polypeptide to bind CH3-specific affinity media such that the first and second polypeptides have different affinities with respect to CH1 and CH3 specific affinity reagents that allows rapid isolation by differential binding. The invention also provides bispecific antibodies that have CH1 and CH3 regions with different affinities with respect to affinity reagents that allows rapid isolation by differential binding. The invention also concerns bispecific antibodies which are heterodimers of two IgG heavy chains that differ by at least two amino acids that allow for rapid isolation based on a differential affinity of one mutated heavy chain and a second mutated heavy chain toward two different affinity reagents.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: March 1, 2022
    Assignee: NovImmune SA
    Inventors: Nicolas Fischer, Giovanni Magistrelli, Francois Rousseau, Krzysztof Masternak, Pauline Malinge
  • Publication number: 20210253068
    Abstract: The invention relates to a telescopic cleaning device intended to spray at least a first fluid and at least a second fluid toward an exterior surface of a motor vehicle's sensor/emitter, the telescopic cleaning device including at least a first distribution orifice for a first fluid and at least a second distribution orifice for a second fluid, the telescopic cleaning device being configured to deploy along a deployment (D) axis where the first distribution orifice and the second distribution orifice are offset from one another along the cleaning device's axis of deployment (D).
    Type: Application
    Filed: June 12, 2019
    Publication date: August 19, 2021
    Applicant: Valeo Systemes d'Essuyage
    Inventors: Maxime BAUDOUIN, Jordan VIEILLE, Jean-Francois ROUSSEAU, Philippe PICOT
  • Patent number: 11059910
    Abstract: The invention relates to monoclonal and/or monovalent antibodies that bind CD47. The invention relates to monoclonal and/or monovalent antibodies that bind CD19. The invention also relates to novel bispecific monoclonal antibodies carrying a different specificity for each binding site of the immunoglobulin molecule, where one of the binding sites is specific for CD47. The invention also relates to novel bispecific monoclonal antibodies carrying a different specificity for each binding site of the immunoglobulin molecule, where one of the binding sites is specific for CD19.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: July 13, 2021
    Assignee: NovImmune SA
    Inventors: Krzysztof Masternak, Nicolas Fischer, Francois Rousseau, Elie Dheilly, Marie Kosco-Vilbois
  • Patent number: 10982004
    Abstract: Disclosed are antibodies that specifically bind Toll-like Receptor 4 (TLR-4), and to methods of using the anti-TLR4 antibodies as therapeutics and diagnostic agents.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: April 20, 2021
    Assignee: NovImmune SA
    Inventors: Francois Rousseau, Jeremy Loyau, Nicolas Fischer, Greg Elson, Marie Kosco-Vilbois
  • Publication number: 20210107435
    Abstract: The invention relates to a liquid recovery system for a motor vehicle and to a vehicle including such a recovery system that that includes at least one liquid intake that communicates with a tank and is referred to as the first tank, which is designed to store liquid from the liquid intake and where the liquid intake is arrangeably designed below the vehicle's beltline.
    Type: Application
    Filed: May 22, 2019
    Publication date: April 15, 2021
    Applicant: Valeo Systemes d'Essuyage
    Inventors: Laurent ANDRE-MASSE, Philippe CARRARO, Julien CARRION, Pierre-Francois DUPRAT, Jean-Francois ROUSSEAU, Grégory VILLEMIN
  • Patent number: 10919502
    Abstract: The invention concerns a rear view system (1) of a motor vehicle comprising:—an optical image capturing sensor (3),—a protective support (5) comprising a transparent and flat protective screen (7), the optical sensor (3) being installed on the protective support (5) in such a way as to point through said protective screen (7), and—a scraper blade (9) for cleaning the protective screen (7) disposed on the face of the protective screen (7) opposite that of the optical sensor (3) side, characterised in that it further comprises an electromagnetic actuation device (11) for actuating said scraper blade (9) in translation on the protective screen (7).
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: February 16, 2021
    Assignee: Valeo Systèmes d'Essuyage
    Inventor: Jean-François Rousseau
  • Publication number: 20200347143
    Abstract: The present invention relates to a new class of TNFR agonist comprising multiple binding portions to two different parts of the same TNFR. The present invention also relates to methods of activating components of the immune system in a patient via the administration of a TNFR agonist according to the present invention as well as the use of such materials for further therapeutic and other purposes.
    Type: Application
    Filed: December 19, 2017
    Publication date: November 5, 2020
    Applicant: Glenmark Pharmaceuticals S.A.
    Inventors: Stanislas BLEIN, Francois ROUSSEAU, Rami LISSILAA, Jonathan BACK, Julie MACOIN
  • Publication number: 20200231707
    Abstract: The invention relates to antigen-binding proteins or antibodies having heterodimers of heavy chains, i.e., two immunoglobulin heavy chains that differ by at least one or two amino acid(s) that allows for isolation of the antigen-binding protein based on a differential affinity of an immunoglobulin heavy chain and a modified/mutated immunoglobulin heavy chain toward an affinity reagent. The invention also relates antigen-binding proteins, including bispecific antibodies, having IgG CH1 regions with different affinities with respect to affinity reagent(s) that allows rapid isolation by differential binding of the IgG regions to the affinity reagent(s).
    Type: Application
    Filed: November 27, 2019
    Publication date: July 23, 2020
    Applicant: NovImmune SA
    Inventors: Nicolas FISCHER, Giovanni MAGISTRELLI, Francois ROUSSEAU, Krzysztof MASTERNAK, Pauline MALINGE
  • Publication number: 20200207866
    Abstract: Disclosed are antibodies that specifically bind Toll-like Receptor 4 (TLR-4), and to methods of using the anti-TLR4 antibodies as therapeutics and diagnostic agents.
    Type: Application
    Filed: July 19, 2019
    Publication date: July 2, 2020
    Inventors: Francois Rousseau, Jeremy Loyau, Nicolas Fischer, Greg Elson, Marie Kosco-Vilbois
  • Publication number: 20190381975
    Abstract: The subject matter of the present invention is a module (5) for cleaning an optical element protection device (3) intended to equip a motor vehicle, said protection device (3) having a surface of revolution configured to be arranged around the optical element. The cleaning module (5) includes at least one ring (51) configured to surround the protection device (3) and includes at least one wiping structure. The ring (51) is configured to be mobile in relative movement in translation along an axis of revolution (A2) of the ring (51) relative to the protection device (3) such that said at least one wiping structure (53) of the ring (51) is configured to wipe the surface of revolution of the protection device (3).
    Type: Application
    Filed: June 19, 2019
    Publication date: December 19, 2019
    Applicant: Valeo Systèmes d'Essuyage
    Inventors: Gérald Caillot, Giuseppe Grasso, Jean-François Rousseau, Marcel Trebouet, Frédéric Bretagnol, Jean-Michel Jarasson, Frédéric Giraud, Mehdi Belhaj, Jose Luis Herrada
  • Patent number: 10494446
    Abstract: The invention relates to antigen-binding proteins or antibodies having heterodimers of heavy chains, i.e., two immunoglobulin heavy chains that differ by at least one or two amino acid(s) that allows for isolation of the antigen-binding protein based on a differential affinity of an immunoglobulin heavy chain and a modified/mutated immunoglobulin heavy chain toward an affinity reagent. The invention also relates antigen-binding proteins, including bispecific antibodies, having IgG CH1 regions with different affinities with respect to affinity reagent(s) that allows rapid isolation by differential binding of the IgG regions to the affinity reagent(s).
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: December 3, 2019
    Assignee: NovImmune SA
    Inventors: Nicolas Fischer, Giovanni Magistrelli, Francois Rousseau, Krzysztof Masternak, Pauline Malinge
  • Patent number: 10464531
    Abstract: The invention relates to an actuation device for a driving arm (2) of a wiper (3), in particular for a motor vehicle, said device comprising: a body (10) hinged to rotate about a pivot axis and capable of receiving the arm (2), and a means (14) for locking the arm (2) on the body (10), said locking means (14) being hinged with the body (10). The invention also relates to a system for wiping a window of a vehicle, comprising said device.
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: November 5, 2019
    Assignee: Valeo Systèmes d'Essuyage
    Inventor: Jean-François Rousseau
  • Patent number: 10400044
    Abstract: Disclosed are antibodies that specifically bind Toll-like Receptor 4 (TLR-4), and to methods of using the anti-TLR4 antibodies as therapeutics and diagnostic agents.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: September 3, 2019
    Assignee: NovImmune SA
    Inventors: Francois Rousseau, Jeremy Loyau, Nicolas Fischer, Greg Elson, Marie Kosco-Vilbois
  • Publication number: 20180355065
    Abstract: The invention relates to monoclonal and/or monovalent antibodies that bind CD47. The invention relates to monoclonal and/or monovalent antibodies that bind CD19. The invention also relates to novel bispecific monoclonal antibodies carrying a different specificity for each binding site of the immunoglobulin molecule, where one of the binding sites is specific for CD47. The invention also relates to novel bispecific monoclonal antibodies carrying a different specificity for each binding site of the immunoglobulin molecule, where one of the binding sites is specific for CD19.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 13, 2018
    Applicant: NovImmune S.A.
    Inventors: Krzysztof MASTERNAK, Nicolas FISCHER, Francois ROUSSEAU, Elie DHEILLY, Marie KOSCO-VILBOIS