Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a liquid emission mechanism for an inhalation device, as well as a method of emitting a liquid from an inhalation device.

Abstract: The invention relates to the field of inhalation devices for liquids.

Abstract: A micropump and its use, the micropump including a vibration unit with piezo actuator, which is arranged on an vibration diaphragm, a vibration plate arranged opposite the vibration diaphragm and having a blower opening, as well as a wall arranged between the vibration diaphragm and the vibration plate, so that a blower chamber is formed, and a housing, in which the vibration unit is mounted, with an suction opening, as well as an output opening, which lies opposite the blower opening. The housing forms a closed space and has at least one suction opening arranged radially, or on an underside opposite the vibration unit, with a suction channel leading into a pump chamber located between the vibration plate and the inside of the housing.

Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an improved seal construction for an inhalation device having a nebulizing nozzle and a piston which moves relative to a pumping chamber in order to generate pumping pressure and to an inhalation device comprising such seal.

Abstract: The invention relates to the field of inhalation methods and inhalation devices for liquids. In particular, the invention relates to an inhalation method using an inhalation device having a nebulizing nozzle, and to a method for the generation of an aerosol of an aqueous formulation comprising pirfenidone by means of such inhalation device.

Abstract: The invention relates to the field of nozzles for inhalation devices for liquids. In particular, the invention relates to a nebulizing nozzle for an inhalation device, suitable for the generation of an aerosol of a medically active liquid, and to inhalation devices comprising such nozzle. Such nozzle (1) for an inhalation device for medically active liquids (F, F1, F2) for generation of an aerosol has a main axis (Z) and at least three ejection channels (1A, 1B, 1C, 1D) adapted to eject liquid (F, F1, F2) along respective ejection trajectories, wherein at least two collision points (X1, X2) are provided at which at least two of said ejection trajectories intersect with one another, and/or wherein further, all ejection angles (A, A1, A2) at which the individual trajectories leave the nozzle (1) are identical, or at least one of said ejection angles (A, A1, A2) differs from the other ejection angles (A, A1, A2).

Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an inhalation device having a nebulizing nozzle, and to a method for the generation of an aerosol of a medically active liquid by means of such inhalation device.

Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a pumping chamber for such an inhalation device.

Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a nebulizing nozzle to be used in such an inhalation device, as well as a method for fabrication of such a nozzle. A nozzle for an inhalation device for nebulizing a liquid into a respirable aerosol has a nozzle body (1) which has a front end (1B) and which comprises at least two ejection channels (2, 2?), each channel (2, 2?) having an channel exit (2A, 2A?), wherein the ejection channels (2, 2?) are arranged such as to eject liquid along respective ejection trajectories which intersect with one another at a collision point. The nozzle is characterized in that at least one recess (3) is provided at the front end (1B) in which the channel exits (2A, 2A?) are positioned.

Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a fixture for a nebulizing nozzle to be used in such an inhalation device. A nozzle fixing assembly (1) for an inhalation device, comprising an elastically deformable seal element (2), having a continuous opening (3) capable of receiving a nozzle body (4), said seal element (2) and said nozzle body (4) each having a high pressure side (2A, 4A) and an outlet side (2B, 4B); and a pressure element (5) with a high pressure side (5A), said side being arranged to face the high pressure side (2A) of the seal element (2); wherein (i) the high pressure side (2A) of the seal element (2) is substantially flat, and (ii) the high pressure side (5A) of the pressure element (5) is chamfered in a way that, in the assembled state, the distance between these high pressure sides (2A, 5A) is higher in a central region (C) than in a peripheral region (P).

Abstract: The invention relates to a nozzle arrangement for atomizing a fluid flow, which is supplied under pressure, into fine particles, which has: a conical element with an upper surface, a lower surface and an outer surface which is adjacent to the upper and the lower surface, wherein the outer surface has a multiplicity of grooves which are formed therein and extend between the lower surface and the upper surface; and a counter element which is provided with a recess and is designed to receive the conical element and which has an inner surface such that the grooves are at least partially covered by the inner surface in order to form a multiplicity of channels; wherein the channels define outputs in order to let out a respective fluid jet which strikes against at least one other fluid jet in a region spaced apart from the upper surface of the conical element in order thus to atomize the fluid flow, and wherein the conical element is movable along the axis in order to increase or to reduce the effective cross sectio

Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

Abstract: The inhalation device for medically active liquids (F) for generation of an aerosol comprises a housing (1), a reservoir (2), a pumping device with a pumping chamber (3), and a nozzle (6), wherein the interior volume of the pumping chamber (3) is changeable by means of linear relative motion of the pumping chamber to the riser pipe (5). Said linear relative motion can be effected by a relative rotation of a rotatable part (1A) which is part of, or connected to, the housing (1) with respect to a second part (1B) of said housing (1), in that said relative rotation can be transferred by means of a gear mechanism into said relative translational motion. A means for the storage of potential energy (7) is provided which is chargeable by means of said relative rotation, and wherein said energy is releasable to said pumping device when released by activation of a release means.

Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

Abstract: The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an inhalation device having improved flow characteristics.

Abstract: A whole blood filtration device is provided with a filter membrane separating a feeding volume and a clean side of the filter membrane from each other. The feeding volume communicates with a first feeding side opening and with a second feeding side opening. The filter membrane has pores with a pore size that ensures permeability of the filter membrane to blood plasma/serum and that retains blood cells. The first feeding side opening can be coupled to a first blood pump for feeding blood from the first feeding side opening into the feeding volume so that blood plasma/serum permeates the filter membrane and blood cells, retained by the filter membrane, exit from the feeding volume through the second feeding side opening.

Abstract: A blood filtering device has a filtration section with filter medium separating raw side and clean side. A first communication path connects raw side and a first variable blood reservoir volume; a second communication path connects raw side and a second variable blood reservoir volume coupled to a receptacle. When varying the first variable blood reservoir volume, blood contained therein flows through first communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through second communication path into the second variable blood reservoir volume. When varying the second variable blood reservoir volume, blood contained therein flows through second communication path to raw side, plasma/serum passes through the filter medium from raw side to clean side, and residual blood flows from raw side through first communication path into first variable blood reservoir volume.

Abstract: The invention relates to an atomiser, in particular an inhaler, for atomising a liquid active agent to form an aerosol, having an active agent reservoir (1), an atomiser nozzle (2) and a pump arrangement (3), wherein a suction side (4) of the pump arrangement (3) leads into the active agent reservoir (1) and a pressure side (5) of the pump arrangement (3) leads into the atomiser nozzle (2), and wherein the pump arrangement (3) has a plunger (7) that can be adjusted in a cylinder (6) in the axial direction (x) of the cylinder (6), characterised in that the plunger (7) is supported in portions along its outer circumference (8) in a form-fitting manner on an inner wall (9) of the cylinder (6) and a gap (10) is formed in portions between the inner wall (9) of the cylinder (6) and the plunger (7), wherein the plunger (7) is rotatably mounted around its longitudinal axis (x) in the cylinder (6) and can be adjusted between a suction position, in which a pump chamber (11) of the pump arrangement (3) is connected to t

Abstract: The invention relates to a valve, in particular for a device for administering a liquid medicament, with a valve body (1) which has an interior (2) for receiving a liquid (20), wherein the valve body (1) has a liquid inlet (3) and an opposite liquid outlet (4) which both open into the interior (2), wherein the interior (2) accommodates a large number of micro channels (5) which extend in connection direction (x) between the liquid inlet (3) and the liquid outlet (4). A corresponding device for administering a liquid medicament is also described.

Abstract: A filter element for filtering liquids has a folded filter medium with outer fold edges and inner fold edges, wherein the inner and outer fold edges extend along a longitudinal axis of the filter element. A support body is provided with a first support body section and a second support body section, wherein the first support body section is facing the inner fold edges and hugs closely an envelope of the inner fold edges. An envelope of the outer fold edges and the second support body section hug closely at least sectionwise an outer circumferential surface of the filter element.